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1.
Med Oral Patol Oral Cir Bucal ; 16(5): e688-93, 2011 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-20711104

RESUMO

OBJECTIVE: To determine the frequency of appearance and the factors most commonly associated with ocular complications following dental local anesthesia, also establishing the location and type of anesthesia used. STUDY DESIGN: An indexed search in the Pubmed and Compludoc databases was carried out with the keywords "oral anesthesia", "ocular", "ophthalmologic", "damage", "complications", "injection". We established a limitation that the literature had to have been published after the year 1970. A total of 19 articles were obtained, forming a total sample of 37 patients. The patient's sex, age, nerve anesthetized, type of anesthetic used, ophthalmological complication present, recovery time, treatment and side effects were analyzed. RESULTS: There is a higher involvement of females (77%). The average age was 34.2 years. There was no preference for an anesthetic technique. Diplopia was the most common complication (65%), which coincides with the data from other authors. Almost all of the complications were of a temporary nature, with an average recovery time of 68 minutes. CONCLUSIONS: This is one of the few studies of its kind in dental literature, it thus being difficult to make precise conclusions. Ophthalmological complications are seldom a problem, diplopia being the most common among them. The authors appear to indicate an intravascular injection of the anesthetic as the cause of the problem, and therefore, it should be avoided in order to prevent accidents at the ocular level.


Assuntos
Anestesia Dentária/efeitos adversos , Anestesia Local/efeitos adversos , Oftalmopatias/etiologia , Adulto , Feminino , Humanos , Masculino
2.
Av. odontoestomatol ; 25(1): 11-18, ene.-feb. 2009. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-85491

RESUMO

El liquen plano oral (LPO) es una enfermedad mucocutánea inflamatoria crónica, con una etiología aún desconocida, de base autoinmune, que suele cursar con manifestaciones orales, con una clínica e histología características y de curso evolutivo benigno, pero susceptible de transformación maligna. En los últimos años se ha investigado la relación entre su patogenia y los mecanismos apoptóticos de destrucción celular. Material y método: Búsqueda bibliográfica en el servidor de la U.S. National Library of Medicine and the National Institutes of Health (Pubmed) con las palabras clave “apoptosis AND oral lichen planus”. Discusión: Existen diferentes estudios que evalúan la relación de los diferentes marcadores apoptóticos (TNF-α, bcl-2, Fas, p53, BMP-4, granzima B, MMP…) con la patogenia, evolución, clínica y malignización del LPO. Para la determinación de estos factores se emplean técnicas de anatomía patológica e inmunohistoquímica(TUNEL, PCR,…).Conclusión: no existe consenso en los resultados y las consiguientes conclusiones obtenidas en los diferentes estudios sobre la influencia de cada uno de los marcadores apoptóticos en el desarrollo de las lesiones de LPO. Es necesaria una mayor y más profunda investigación en búsqueda de un factor siempre asociado a las formas clínicas agresivas con mayor tendencia a la malignización (AU)


Oral lichen planus (OLP) is a mucocutaneous inflammatory chronic disease, with unknown etiology, autoinmune, usually associated with characteristical oral manifestations. Despite it has a benign evolution, is possible to become malign. Lately, relation between the pathogenesis and apoptotic cells destroy has been investigated. Methods: A bibliography survey was carried out with the U.S. National Library of Medicine and the National Institutes of Health (Pubmed) with the keywords “apoptosis AND oral lichen planus”. Discussion: Several trials evaluate the relationship among several apoptotic markers (TNF-α, bcl-2, Fas, p53,BMP-4, granzyme B, MMP…) and OLP pathogenesis, evolution, clinic and malignization. These studies employed histology and immunohistochemistry (TUNEL, PCR)Conclusion: Lack of consensus on results and conclusions about the influence of each apoptotic marker in the OLP development. Further investigation is required to obtain an apoptotic marker strongly associated with aggressive clinic and high-risk of malignancy (AU)


Assuntos
Humanos , Apoptose/fisiologia , Líquen Plano Bucal/fisiopatologia , Fator de Indução de Apoptose/análise , Proteína Supressora de Tumor p53/análise , Queratinócitos , Proteínas Proto-Oncogênicas c-bcl-2/análise , Fatores de Risco
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