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Mymensingh Med J ; 30(4): 1079-1085, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34605480


Complete assessment of obstructive jaundice requires the use of various imaging modalities that are required to detect the cause and level of obstruction thus helping in treatment planning. Magnetic Resonance Cholangio Pancreatography (MRCP) is a current available technology which is a non-invasive technique that visualizes the gallbladder, biliary tree and pancreatic duct and also provides information about surrounding structures. This study was done to correlate the MRCP findings with post-operative result and thereby demonstrate the specificity, sensitivity and efficacy of MRCP as an accurate investigatory tool for biliary obstruction. Total of fifty (50) patients of clinically diagnosed obstructive jaundice were studied from March 2017 to August 2017 in the Department of Radiology and Imaging, Combined Military Hospital, Dhaka, Bangladesh. In all these cases, USG was the initial screening investigation followed by MRCP. Cause and level of obstruction were evaluated using MRCP findings. MRCP results were correlated with surgical findings and few cases also with direct ERCP findings. Statistical analysis was done to see the sensitivity, specificity, accuracy, positive and negative predictive values of MRCP in diagnosis of biliary obstruction. In this study, USG detected level of obstruction in 56% (28 out of 50) cases. USG could detect causes of obstruction in 100% (02 out of 02) cases of choledocal cyst and 66.67% (02 out of 03) benign stricture, 60% (03 out of 05) cases of periampullary carcinoma, 57.70% (06 out of 14) cases of choledocholithiasis, and 42.86% (15 out of 26) cases of cholangiocarcinoma. On the other hand, MRCP detected level of obstruction in 98% (49 out of 50) cases. MRCP could detect causes of obstruction in 100% cases of cholangiocarcinoma, choledocholithiasis, benign stricture and choledocal cyst and 80% (04 out of 05) cases of periampullary carcinoma. In this study, ERCP could detect causes of obstruction in 32 cases of choledocholithiasis and benign stricture, but in case of cholangiocarcinoma ERCP was failed in 3 cases. In this study, for detection of cause of obstruction, ERCP had the highest sensitivity (97.79%); followed by MRCP (96.65%) and USG (60.25%). The overall diagnostic accuracy for detection of cause of obstruction was the highest for ERCP (95.50%); followed by MRCP (94.50%) and USG (64.50%). MRCP can be done in a short duration and is a noninvasive diagnostic modality compared to ERCP. MRCP needs to be advocated as a viable and non-invasive alternative with compararable sensitivity and specificity to ERCP.

Neoplasias dos Ductos Biliares , Colangiocarcinoma , Colestase , Bangladesh , Ductos Biliares Intra-Hepáticos , Colangiopancreatografia por Ressonância Magnética , Colestase/diagnóstico por imagem , Colestase/etiologia , Humanos
Histopathology ; 4(2): 147-54, 1980 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-7358344


Two cases of sex cord tumour of the ovary with annular tubules were diagnosed in African females of 23 and 57 years. In one case it was associated with the Peutz-Jeghers syndrome and with Stein-Leventhal ovaries whilst in the other case, pigmentation of the oral mucosa was present but without demonstrable polyposis of the intestine. The patient with the Peutz-Jeghers syndrome presented with primary sterility whilst the other patient had a normal menstrual and obstetric history. Signs of virilization were not found in either case. The previously reported literature is reviewed and discussed.

Neoplasias Ovarianas/patologia , Ovário/patologia , Adulto , Núcleo Celular/patologia , Citoplasma/patologia , Endométrio/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Folículo Ovariano/patologia , Neoplasias Ovarianas/complicações , Síndrome de Peutz-Jeghers/complicações , Útero/patologia