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1.
Oral Oncol ; 108: 104910, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32771332

RESUMO

Lymphoblastic lymphoma (LBL) is a clinically aggressive disease, representing approximately 2% of all non-Hodgkin lymphoma cases. In the oral and maxillofacial (OMF) region, approximately 39 cases, diagnosed as LBL, acute lymphoblastic leukemia (ALL) or ALL/LBL, have been reported to date. Noteworthy, the CD9 expression, which indicates a poor outcome in ALL, has not been reported in LBL and lymphoblastic neoplasms of the OMF region. Herein, we report an additional maxillary intraosseous B-cell LBL, affecting a 14-year-old girl, which also showed positivity for CD9, Bcl-6 and MUM1/IRF4. Aiming at diagnostic and prognostic criteria, further studies focusing CD9 expression in LBL is recommended.


Assuntos
Imuno-Histoquímica/métodos , Hibridização In Situ/métodos , Maxila/patologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicações , Adolescente , Feminino , Humanos
2.
Oral Oncol ; 109: 104857, 2020 Jun 23.
Artigo em Inglês | MEDLINE | ID: mdl-32590299

RESUMO

Besides the Waldeyer's ring, other lymphoid aggregates can also be detected in the soft palate, floor of the mouth and ventral tongue. The lingual tonsil is located at the base of the tongue and related to circumvallate papillae, whereas subepithelial lymphoid tissue at the posterior lateral portion of the tongue and related to foliate papillae constitutes the lateral lingual tonsil. Unilateral tonsillar enlargement is critical, because it can suggest malignancy, notably non-Hodgkin lymphoma or squamous cell carcinoma. Herein, we report an unusual presentation of unilateral enlargement of the lateral lingual tonsil, diagnosed as follicular lymphoid hyperplasia.

3.
Oral Oncol ; 107: 104826, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32505552

RESUMO

Myopericytoma is a rare mesenchymal tumor characterized by a hemangiopericytoma-like vascular pattern with perivascular myoid differentiation. To date, only 11 cases of oral myopericytoma have been reported. To the best of our knowledge, myopericytoma with gingival involvement and associated with calcifications has not been reported, expanding their clinicopathological spectrum. Herein, we report a 12-year-old girl female patient who presented a gingival nodule diagnosed as ossifying myopericytoma, which should be considered in the differential diagnosis when assessing oral soft tissue lesions, especially in pediatric patients.


Assuntos
Imuno-Histoquímica/métodos , Miopericitoma/terapia , Criança , Feminino , Humanos , Miopericitoma/imunologia
4.
Head Neck Pathol ; 12(1): 75-81, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28597210

RESUMO

Cellular neurothekeomas (CNs) are distinctive benign tumors of uncertain histogenesis, with predilection for the skin of the head and neck region. We describe the first case of multiple desmoplastic CNs (DCNs) affecting the oral cavity in a 9-year-old girl. Histopathologic evaluation showed a proliferation of spindle and epithelioid cells, forming nests and bundles, supported by exuberant fibrous stroma, as well as scattered multinucleated floret-like giant cells. The tumor cells were immunopositive for vimentin, CD63, CD56, whereas AE1/AE3, S100, CD34, α-SMA, GFAP, EMA, CD57 and NSE were negative. Ki-67 was <2%. Multiple DCNs should be considered in the differential diagnosis of oral nodular lesions.


Assuntos
Neoplasias Bucais/patologia , Neoplasias Primárias Múltiplas/patologia , Neurotecoma/patologia , Biomarcadores Tumorais/análise , Criança , Feminino , Humanos
5.
Quintessence Int ; 42(8): 701-9, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21842010

RESUMO

OBJECTIVE: To compare the prevalence of orofacial manifestations between patients with and without sickle cell anemia and to investigate the distribution of such events in patients with sickle cell anemia by sex and age. METHOD AND MATERIAL: A cross-sectional study was conducted in which 330 subjects divided into two groups (a group of individuals with sickle cell anemia and a healthy control group) were examined. RESULTS: It was observed that patients with sickle cell anemia had a significantly higher prevalence of previous mental nerve neuropathy (P = .000) and delayed tooth eruption (P = .006) than patients without the disease. Regarding the distribution of orofacial manifestations in patients with sickle cell anemia by sex and age, the only statistical associations were between the prevalence of previous mental nerve neuropathy and sex (P = .023) and previous mandibular pain and age (P = .019). CONCLUSIONS: This study found that sickle cell anemia is associated with the prevalence of previous mental nerve neuropathy and delayed tooth eruption. Moreover, previous mental nerve neuropathy is more frequent among females with sickle cell anemia, and previous mandibular pain is more frequent among individuals older than 21 years of age with sickle cell anemia. Further studies using a methodology similar to the one in this study are necessary considering the scarcity of studies using this approach.


Assuntos
Anemia Falciforme/complicações , Dor Facial/etiologia , Doenças da Boca/etiologia , Doenças Dentárias/etiologia , Adolescente , Adulto , Distribuição por Idade , Brasil , Estudos de Casos e Controles , Criança , Pré-Escolar , Doenças dos Nervos Cranianos/etiologia , Estudos Transversais , Feminino , Humanos , Lactente , Modelos Logísticos , Masculino , Nervo Mandibular , Pessoa de Meia-Idade , Razão de Chances , Distribuição por Sexo , Erupção Dentária , Adulto Jovem
6.
Arq. odontol ; 47(1): 31-37, Jan.-Mar. 2011. graf, tab
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-725229

RESUMO

Objetivo: O presente estudo objetivou analisar a produção científica odontológica na área de saúde coletiva a partir de periódicos indexados na base de dados Scientific Eletronic Library Online (SciELO), sessão Saúde Pública. Materiais e Métodos: Foram analisados 10 periódicos, sessão Saúde Pública, com 605 números, totalizando 8.494 artigos científicos, indexados no SciELO e publicados entre janeiro de 1998 e dezembro de 2007. Resultados: Verificou-se que em relação à produção científica, das 8.494 publicações, 260 eram da área odontológica, correspondendo a 3% da produção analisada. A maior produção de artigos científicos concentrou-se no periódico Cadernos de Saúde Pública (26,5%) e a menor, na Revista de Salud Pública da Colômbia (2%). A maior parcela da produção científica originou-se de Instituições de Ensino Superior (48%). Dessas, 76,5% foi oriunda de instituições públicas localizadas, principalmente, no Sudeste do Brasil (54%). Conclusão: Foi possível observar, portanto, a crescente produção científica da área de saúde bucal coletiva brasileira, evidenciando-se uma maior concentração na região sudeste e uma grande participação das instituições de ensino superior.(AU)


Aim: This study aimed to analyze the dental scientific production in the area of Public Health, from periodicals indexed in the Scientific Electronic Library Online (SciELO) database. Materials and Methods: The present study analyzed 10 journals, in the area of public health, with 605 editions, totaling 8.494 articles, indexed in SciELO and published between January 1998 and December 2007. Results: Considering the total number of published articles (n=8.494), 260 were associated with dentistry, corresponding to 3% of the analyzed production. The largest scientific article production was concentrated in the Public Health Journals (26.5%), whereas a lesser amount could be found in the Revista de Salud Pública (Public Health Journal, Colombia) (2%). The great majority of scientific production came from institutions of higher education (48%), 76.5% of which came from public institutions, located mainly in the Southeastern regions of Brazil (54%). Conclusion: The results demonstrated the growth of scientific literature on public health in Brazil, but with obvious regional bias and prominent involvement of institutions of higher education.(AU)


Assuntos
Bibliometria , Saúde Bucal , Publicação Periódica , Saúde Pública , Base de Dados , Jornais como Assunto
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