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Clin Exp Dent Res ; 6(4): 428-432, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32246747


OBJECTIVES: Serum level of vitamin D has been used as a predictor for cancer development. We intend to measure the baseline vitamin D level in patients with oral squamous cell carcinoma (OSCC) and to compare same with non-cancer controls to determine any association. MATERIALS AND METHODS: Patients with OSCC presenting to our clinics were included in this study. Their baseline serum vitamin D levels were measured prior to cancer treatment after obtaining their consents. These patients were then matched with at least 2 cancer-free subjects to serve as controls and whose serum vitamin D levels were also measured. The serum vitamin D levels obtained for the two groups were then categorized into normal (>35 ng/ml), mild deficiency (25-35 ng/ml), moderate deficiency (12.5-25 ng/ml), and severe deficiency (<12.5 ng/ml). The data were analyzed statistically and the two groups compared. RESULTS: A total of 51 patients with OSCC (Male 22 [43%] and female 29 [57%]) and 113 cancer-free controls (Male 36 [31.86%] and female 77 [68.14%]) were included in the study. The commonest site for OSCC was the tongue, accounting for 45% of the cancer cases. Mean age for cancer patients was 59.33 years ±12.54 and 49.24 years ±15.79 for the control. Among the OSCC patients, 74.51% had moderate to severe vitamin D deficiencies, whereas only 20.35% had a moderate deficiency in the control group with no severe deficiency. CONCLUSION: Logistic regression analysis shows a positive association between vitamin D deficiency and OSCC risk especially in levels below 25 ng/ml. This further corroborates the assertion that vitamin D deficiency may be a useful indicator of OSCC. It may, therefore, be necessary to routinely prescribe vitamin D supplements to subjects with moderate to severe deficiencies in order to decrease the chances of OSCC development.

Carcinoma de Células Escamosas/sangue , Suplementos Nutricionais , Neoplasias Bucais/sangue , Deficiência de Vitamina D/fisiopatologia , Vitamina D/análogos & derivados , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma de Células Escamosas/tratamento farmacológico , Carcinoma de Células Escamosas/epidemiologia , Estudos de Casos e Controles , Quimioprevenção , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/tratamento farmacológico , Neoplasias Bucais/epidemiologia , Prognóstico , Vitamina D/administração & dosagem , Vitamina D/sangue , Deficiência de Vitamina D/tratamento farmacológico
Mater Sociomed ; 30(1): 58-61, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29670479


Objectives: To assess the prevalence of periodontal disease among patients undergoing renal dialysis. Methods: Sixty hemodialysis patients (30 males, 30 females) with a mean age of 44.4±9.5 years comprised the study group. Periodontal parameters such as plaque index (PI), bleeding on probing (BOP), probing pocket depth (PPD) and clinical attachment level (CAL) were measured in these patients and 60 age and sex-matched control subjects. The data was tabulated and analyzed. Results: The mean duration of dialysis was 5.50±3.02 years. The plaque index (PI) bleeding on probing (BOP), Periodontal probing depth (PPD) and clinical attachment level (CAL) were significantly higher in patients undergoing hemodialysis than in control subjects. The mean clinical attachment level was significantly higher among the dialysis patients (2.78±0.83 mm) than the control subjects (1.97±0.53 mm). The plaque index and bleeding on probing also showed a similar pattern in patients undergoing hemodialysis compared to control patients. The prevalence and severity of periodontal disease seems to be higher in patients undergoing dialysis. Conclusion: From the observations of this study, it can be concluded that patients undergoing hemodialysis are more prone to periodontal diseases. Further studies with a larger population and a comparison with the duration of dialysis may further substantiate the current findings.

J Int Soc Prev Community Dent ; 7(6): 364-369, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29387622


Aims and Objectives: Many situations in the dental office can provoke medical emergencies. Lack of training and inability to overcome the medical emergencies can lead to serious consequences and legal actions. The aim of the study is to investigate and assess the knowledge, attitude, and perceived confidence of dental students and interns in the management of medical emergency. Materials and Methods: A self-administered structured questionnaire was distributed to 153 of the undergraduate dental students and interns in Qassim province. Questionnaire consisted of nineteen questions pertaining to knowledge and awareness regarding syncope, cardiopulmonary resuscitation (CPR), intravenous drugs, measuring vital signs, and handling situation of aspiration of a foreign body, bleeding, and choking. Data were analyzed by Statistical Package for Social Sciences (SPSS) version 21.0. Results: Fifty-seven percent was the response rate received from the questionnaire. Eighty-nine percent and 30% of the participants inquired about the medical history and vital signs before dental treatment, respectively. Only 37% of participants were confident to handle any medical emergency in the dental office. Seventy percent knew the correct location of chest compression and 67% were familiar about the right compression ventilation ratio showing significant difference between academic years and interns (P = 0.003). Females were significantly more aware about the management of bleeding after extraction than the males (65%, and 47%, respectively; P = 0.035). Thirty-five percent and 53% chose the correct management to relieve choking in responsive and unresponsive adult or child, respectively. A total of 28% of the participants reported syncope as the most common emergency situation. Conclusion: Participants were lacking confidence in handling medical emergencies even though the majority of them inquired the medical history. Most of them have a good knowledge regarding CPR, but regarding airway obstruction, the knowledge was not at an acceptable level. Annual basic life support and emergency courses should be mandatory in dental teaching curriculum.

J Contemp Dent Pract ; 16(10): 840-4, 2015 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-26581467


Lymphomas of the oral cavity are rare and typically present as intraosseous lesions that are most commonly diffuse large B-cell type. Diffuse large B-cell lymphoma (DLBCL) is an aggressive B-cell lymphoma histologically characterized by diffuse proliferation of large neoplastic B-lymphoid cells with a nuclear size equal to or exceeding normal histiocytic nuclei. A case of DLBCL of the mandible in an 18 years old male patient is presented. This report discusses this rare malignancy, including clinical presentation, histopathologic features, immunologic profile, treatment and prognosis. Though lymphoma of mandible is rare, it must be considered in differential diagnosis of swellings arising in the region.

Linfoma Difuso de Grandes Células B/diagnóstico , Mandíbula , Neoplasias Mandibulares/diagnóstico , Adolescente , Núcleo Celular , Diagnóstico Diferencial , Humanos , Linfoma Difuso de Grandes Células B/terapia , Masculino , Neoplasias Mandibulares/terapia
J Contemp Dent Pract ; 12(5): 327-32, 2011 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-22269191


UNLABELLED: Learning fine motor skills is a pre-requisite for succeeding in dental practice and it is sometimes challenging for dental students. Most of the methods used in the selection process depend on evaluation of intellectual ability or structured interview while manual competence is not. However, no test on aptitude or manual dexterity is used as criteria. OBJECTIVE: The purpose of the present study intended to evaluate the fine motor skills of beginning dental students which could in turn be used as a method of selection of students for the dental degree admission process. MATERIALS AND METHODS: A study was conducted among 71 second year dental students at College of Dentistry, King Saud University in Riyadh. A test composed of three parts, writing an answer for a question in four lines, drawing a picture of a smile and doing a class 1 amalgam preparation on a plastic molar tooth. The students were evaluated based on their handwriting, basic drawing skills and their skills in performing the tooth preparation by experts in each fields following certain criteria. RESULTS: The results showed a significant correlation between writing and drawing skills and dental skills of the student with p < 0.001. CONCLUSIONS: The results of the current study support the use of the writing or drawing test as one of the test used for the applicants for dental school admission. However, the value given to such test in the selection of students needs further investigations and consensus.

Arte , Escrita Manual , Destreza Motora/fisiologia , Estudantes de Odontologia , Aptidão/classificação , Amálgama Dentário , Preparo da Cavidade Dentária/classificação , Preparo da Cavidade Dentária/instrumentação , Equipamentos Odontológicos de Alta Rotação , Humanos , Masculino , Dente Molar/anatomia & histologia , Arábia Saudita , Critérios de Admissão Escolar , Adulto Jovem