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1.
Int Urol Nephrol ; 51(10): 1709-1713, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31309391

RESUMO

PURPOSE: In view of the differences in early and late management experiences based on Huang and Tseng CT classification of emphysematous pyelonephritis (EP), our study included 34 patients aimed to re-correlate the current management plans with CT classification. METHODS: A retrospective review from January 2009 to December 2018, in patients with primary or final diagnosis of EP. Data included; patients' demographics, routine laboratory and imaging work-up. CT was performed for all, and images were classified based on Huang and Tseng classification. The CT classification was correlated to the laboratory parameters and the final treatment plans. Data were collected and analyzed using SPSS®. RESULTS: Complete data for 34 patients were analyzed. The majority (70%) had positive urine culture, and Carbapenems and Ureidopenicillin were the most commonly used antibiotics. Based on CT classification, 75% (26/34) of the patients were in class I and II, 6 cases with class IIIa, and only two with class IIIb, with no cases of class IV. All patients in class I and II responded well to the medical therapy, and eight required PCN/DJ. Four required nephrectomy in class III, with zero mortality. CONCLUSION: Patients in class I and II comprise the majority of EP patients, and respond well to medical treatment with excellent outcome. Insertion of PCN and DJ are not required routinely, but with urinary obstruction requiring drainage, and a few cases who required nephrectomy-all with class III. Our data show improvement in the overall survival in patients for EP.

4.
Urology ; 81(4): 723-6, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23465152

RESUMO

OBJECTIVE: To assess the clinical relevance of small, asymptomatic, noninfection residual stone fragments (≤5 mm) after percutaneous nephrolithotomy (PNL), evaluated using spiral noncontrast-enhanced computed tomography (NCCT). MATERIALS AND METHODS: The present retrospective study included 75 patients who underwent PNL and were proved to have a single residual caliceal stone ≤5 mm as evaluated postoperatively by NCCT. All patients were free of urinary tract infections. The outcome of these residual fragments (RFs) were reassessed ≥12 months later using NCCT. RESULTS: The mean follow-up period was 36.2 ± 20.1 months (range 12-96). Of the 75 evaluated patients, 25 (33.3%) passed the stones spontaneously during the follow-up period, 22 (29.35%) had stable asymptomatic RFs, 25 (33.3%) showed regrowth of the RFs, and 3 patients (4%) presented with slippage of the stones into the ureter. Asymptomatic patients with stable RFs elected to continue follow-up. For the remaining patients, 14 (18.7%) and 9 (12%) were referred to shock wave lithotripsy and PNL, respectively. The 3 patients with ureteral stones were treated with ureteroscopy. Only the RF size (>3 mm) correlated significantly with RF growth or ureteral obstruction (odds ratio 1.882, 95% confidence interval 0.919-3.854; P = .05). CONCLUSION: Small RFs (≤5 mm) after PNL, as assessed by NCCT, should be expected to require active intervention in one third of the patients at intermediate follow-up. A small, single, RF (≤3 mm), as assessed by NCCT, can be considered clinically insignificant.


Assuntos
Cálculos Renais/diagnóstico por imagem , Adolescente , Adulto , Idoso , Feminino , Humanos , Cálculos Renais/cirurgia , Masculino , Pessoa de Meia-Idade , Nefrostomia Percutânea , Estudos Retrospectivos , Tomografia Computadorizada Espiral , Adulto Jovem
5.
Urology ; 81(4): 880-4, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23395121

RESUMO

OBJECTIVE: To define the preoperative kidney and stones characteristics on noncontrast-enhanced computed tomography that affect the success of extracorporeal shockwave lithotripsy (SWL) for treatment of renal calculi in pediatric patients. MATERIALS AND METHODS: From 2005 to 2011, 57 children (age <16 years) with documented preoperative noncontrast-enhanced computed tomography scans underwent SWL for treatment of renal stones and were included in the present study. Stone size, site, multiplicity, average skin-to-stone distance, stone attenuation value, and kidney morphology were determined from the preoperative noncontrast-enhanced computed tomography scans. Success was defined as radiographically stone-free status at the 3-month follow-up examination after a single lithotripsy session without the need for additional sessions or ancillary procedures. RESULTS: After a single session of SWL, 24 children (42.1%) were stone free on the 3-month follow-up imaging study without the need for additional SWL sessions. Treatment failed in 33 patients (57.9), with residual fragments in 30 children, of whom 29 required repeat SWL, and 3 with stones that were considered unchanged and were finally treated with percutaneous nephrolithotomy. Logistic regression analysis revealed that stone attenuation in Hounsfield units (HU) and stone length were the only significant predictors of success. When the HU were stratified into 2 groups of ≤600 and >600 HU, the SWL success rate was 82.1% and 20%, respectively (P = .023). When length was stratified as ≤12 mm and >12 mm, the stone-free rate was 58.6% and 25.1%, respectively (P = .016). CONCLUSION: Stone attenuation ≤600 HU and stone length ≤12 mm were significant independent predictors of SWL success in children.


Assuntos
Cálculos Renais/diagnóstico por imagem , Cálculos Renais/cirurgia , Nefrolitíase/diagnóstico por imagem , Nefrolitíase/cirurgia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Cálculos Renais/patologia , Litotripsia , Masculino , Estudos Retrospectivos , Fatores de Risco , Tomografia Computadorizada por Raios X
6.
Int J Urol ; 20(12): 1205-10, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23441845

RESUMO

OBJECTIVES: To define factors affecting the stone-free rate of extracorporeal shockwave lithotripsy in the treatment of pediatric renal calculi, and to establish a regression model for pretreatment prediction of stone-free probability. METHODS: From January 1999 through February 2012, 207 children with mean age 6.4 ± 3.8 years underwent shockwave lithotripsy with Dornier Lithotripter S for treatment of renal stones. The stone-free rate was evaluated 3 months after the last shockwave lithotripsy session with non-contrast computed tomography. Treatment success was defined as complete clearance of the stones with no residual fragments. Multivariate logistic regression analysis was used to identify independent risk factors and to predict the probability of being stone free. RESULTS: The mean length of the stone was 11.6 ± 4 mm. The stone-free rate was 71%. Independent factors that adversely affect stone-free rate were increasing stone length and calyceal site of the stone. Relative risks for not being free of stones were 1.123 for stone length, 2.673 for stones in the upper or middle calyx and 4.208 for lower calyx stones. CONCLUSION: Stone length and location are prognostic factors determining stone-free rate after shockwave lithotripsy for renal calculi in pediatric patients. Based on our analysis, shockwave lithotripsy should be recommended for renal pelvis stones up to 24 mm, upper or middle calyceal stones up to 15 mm and lower calyceal stones up to 11 mm.


Assuntos
Cálculos Renais/epidemiologia , Cálculos Renais/terapia , Litotripsia/estatística & dados numéricos , Complicações Pós-Operatórias/epidemiologia , Criança , Pré-Escolar , Intervalo Livre de Doença , Feminino , Humanos , Litotripsia/efeitos adversos , Modelos Logísticos , Masculino , Análise Multivariada , Prognóstico , Medição de Risco/métodos , Fatores de Risco , Resultado do Tratamento
7.
BJU Int ; 111(4): 666-71, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22924860

RESUMO

UNLABELLED: WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Extracorporeal shockwave lithotripsy is effective for the treatment of paediatric renal stones with favourable short-term safety. Extracorporeal shockwave lithotripsy for treatment of paediatric renal stones is also safe for the kidney and the child on long-term follow-up. OBJECTIVE: To evaluate the long-term effects of extracoporeal shockwave lithotripsy (SWL) for treatment of renal stones in paediatric patients. PATIENTS AND METHODS: A database of paediatric patients who underwent SWL monotherapy for treatment of renal stones from September 1990 through to January 2009 was compiled. This study included only patients with follow-up for more than 2 years. The long-term effects of SWL were evaluated at the last follow-up with measurement of patients' arterial blood pressure, estimation of random blood sugar and urine analysis. The results of diastolic blood pressure were plotted against a standardized age reference curve. The treated kidney was examined by ultrasonography for measurement of renal length and detection of stones. The measured renal lengths were plotted against age-calculated normal renal lengths in healthy individuals. RESULTS: The study included 70 patients (44 boys (63%) and 26 girls) with mean age at the time of SWL 6.5 ± 3.6 years (range 1-14). The mean follow-up period was 5.2 ± 3.6 years (range 2.1-17.5). The mean age at last follow-up was 11.7 ± 5.3 years (range 4.4-27.5). No patients developed hypertension or diabetes. Only one treated kidney was smaller than one standard deviation of the calculated length. The cause of this was obstruction by a stone in the pelvic ureter 3 years after SWL. CONCLUSION: The long-term follow-up after SWL for treatment of renal stones in paediatric patients showed no effect on renal growth and no development of hypertension or diabetes.


Assuntos
Cálculos Renais/terapia , Litotripsia/métodos , Segurança do Paciente , Adolescente , Fatores Etários , Criança , Desenvolvimento Infantil/fisiologia , Pré-Escolar , Estudos de Coortes , Bases de Dados Factuais , Diabetes Mellitus/diagnóstico , Diabetes Mellitus/epidemiologia , Feminino , Humanos , Hipertensão/diagnóstico , Hipertensão/epidemiologia , Cálculos Renais/diagnóstico por imagem , Litotripsia/efeitos adversos , Masculino , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/fisiopatologia , Estudos Retrospectivos , Medição de Risco , Índice de Gravidade de Doença , Tempo , Resultado do Tratamento , Ultrassonografia
8.
World J Urol ; 28(2): 199-204, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19517113

RESUMO

PURPOSE: Presentation of bladder exstrophy epispadias complex (BEEC) during adulthood is rare. A major surgical challenge encountered in adults with BEEC is the closure of the anterior abdominal wall defect. In this case series we report our experience with the abdominal closure without osteotomy. MATERIALS AND METHODS: Five adult male patients with BEEC were managed at our center. None of the patients had any prior attempts of surgical correction. A right renal tumor was incidentally discovered in one patient and a right partial nephrectomy was performed. All patients underwent urinary diversion and abdominal wall closure at the same operative setting except one. Cystectomy was performed in two patients while the vesical plate muscular coat was utilized for providing support to the anterior abdominal wall in the other three patients. One patient underwent an ileal conduit, while the other patients underwent continent cutaneous diversion. None of our patients underwent osteotomy. RESULTS: Follow-up ranged from 6 to 52 months (mean = 31). Patients who underwent continent cutaneous diversion were continent by day and night. One patient had wound infection and partial disruption and secondary sutures were performed. One patient developed stomal stenosis and was managed by stomal dilatation. All patients showed marked satisfaction with their body image following surgery. CONCLUSION: Management of BEEC in adults is challenging. Utilization of the vesical plate muscular coat for supporting the anterior abdominal wall is a reliable method for abdominal reconstruction. Urinary diversion and abdominal wall closure in one surgical procedure without osteotomy is feasible.


Assuntos
Parede Abdominal/cirurgia , Extrofia Vesical/cirurgia , Epispadia/cirurgia , Derivação Urinária/métodos , Procedimentos Cirúrgicos Urológicos Masculinos/métodos , Músculos Abdominais/cirurgia , Adulto , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Osteotomia , Satisfação do Paciente , Ossos Pélvicos , Complicações Pós-Operatórias/prevenção & controle , Qualidade de Vida , Inquéritos e Questionários , Adulto Jovem
9.
J Urol ; 181(6): 2684-7; discussion 2687-8, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19375100

RESUMO

PURPOSE: Vesical stones are common in children in developing countries. Cystolithotomy is the traditional treatment but a percutaneous approach has been advocated. The aim of this study was to evaluate retrospectively our experience with percutaneous cystolithotomy, cystolitholapaxy and open cystolithotomy in children with bladder stones. MATERIALS AND METHODS: A total of 107 children (96 boys and 11 girls) with vesical stones were treated at our center between January 1992 and March 2008. Mean patient age at the time of diagnosis was 5 years (range 2 to 15). The patients were stratified retrospectively into 2 groups according to the procedure of stone removal. Group 1 (53 patients) underwent open cystolithotomy, and group 2 (54) underwent endourological treatment via the transurethral route (27) or the suprapubic approach (27). Stone size ranged from 0.7 to 5 cm (mean 2.8). RESULTS: In all cases the stones were removed successfully. Operative time was comparable in both groups. The hospital stay was significantly shorter after endourological procedures compared to open surgery (2.6 vs 4.8 days, p <0.05). In the open surgery group 1 patient had a small intestinal injury that necessitated repair, while in the endourological group 2 patients had urinary extravasation (1 urethral and 1 vesical). There were no early or late complications in group 1. In comparison, 4 patients (7.4%) in group 2 had early complications in the form of persistent urinary leakage from the suprapubic site and 1 patient had a bulbous urethral stricture 1 year after transurethral stone disintegration. CONCLUSIONS: Open and endourological management of vesical stones in children is efficient, with a low incidence of complications. Endourological management offers a shorter hospital stay compared to open surgery. However, open cystolithotomy seems to be safer.


Assuntos
Cistectomia/métodos , Cistoscopia , Cálculos da Bexiga Urinária/cirurgia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Estudos Retrospectivos
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