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1.
Cytokine ; 134: 155196, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32683106

RESUMO

OBJECTIVES: There is some evidence for beneficial effects of exercise on cytokines in people with multiple sclerosis (MS), but it is unclear if such effects differ by disability status (i.e., stage of the disease). This study investigated the effect of combined exercise training on pentraxins and pro- inflammatory cytokines in people with multiple sclerosis as a function of disability status. METHODS: This randomized control trial included 94 women with MS who were randomly assigned into exercise or control conditions with randomization stratified by Expanded Disability Status Scale (EDSS) scores of low (EDSS < 4.5), moderate (4.5 ≤ EDSS ≤ 6), or high (EDSS ≥ 6.5) disability. The exercise program lasted 12 weeks and comprised resistance, endurance, Pilates, balance and stretch exercises performed? days/week; the control condition involved a waitlist control. We measured resting levels of inflammatory factors, functional capacity, and lipid profile before and after the 12-week intervention period. RESULTS: Combined exercise training significantly decreased hs-CRP (p = 0.029) and IL-6 (p = 0.001) and increased PTX-3 (p = 0.001) and IFN-Æ´ (p = 0.001), but there was no significant change in Fibrin D-dimer (FDD) (p = 0.876) compared with control, and those effects were independent of disability status. 1RM for lat pull-down, knee extension, and seated row and 6MWT (i.e., walking further) significantly increased and TUG performance significantly decreased (i.e., faster performance) (all, p < 0.001) after combined exercise compared with control, and this too was independent of disability status. CONCLUSIONS: Exercise may stimulate anti-inflammatory effects in MS, and this is generally not influenced by disability status. Exercise training may be an adjuvant for disease-modifying therapy among people with MS, and such effects might not be moderated by disability status.

2.
Mult Scler Relat Disord ; 43: 102143, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32473563

RESUMO

BACKGROUND: To date, studies examining the effect of exercise on neurotrophic factors in MS are contradictory, and this may be explained, in part, by moderators such as disability status. To investigating the effect of a 12-week (3sessions/week) supervised multimodal exercise program on neurotrophic factors levels. METHODS: Ninety four women with MS were randomly assigned into exercise or control conditions with randomization stratified by Expanded Disability Status Scale (EDSS) scores of low (EDSS< 4.5), moderate (4.5 ≤EDSS≤ 6), or high (EDSS≥ 6.5) disability. The exercise program comprised resistance, endurance, Pilates, balance and stretch exercises. Resting level of neurotrophic factors, aerobic capacity, one-repetition maximum, and physiological cost index (PCI) were evaluated before and after the intervention period. RESULTS: Exercise training improved brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-3, and NT-4/5 levels. The effect of exercise on NT-3 was dependent on disability status such that exercise groups with low and high disability had more pronounced changes compared with other condition. There were no exercise effects on ciliary neurotrophic factor (CNTF) and glial cell-derived neurotrophic factor (GDNF). Aerobic capacity and one-repetition maximum, but not PCI, were improved with exercise independent of disability status. CONCLUSIONS: Exercise can stimulate neurotrophic production and secretion, and this is generally not influenced by disability status. Exercise training may be an adjuvant for disease-modifying therapy among people with MS, and its effect may not be moderated by disability status.

3.
Exp Gerontol ; 135: 110884, 2020 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-32092502

RESUMO

The main purpose of present study was to investigate the effects of elastic band resistance training (EBRT) on muscle quality (MQ), serum osteosarcopenic obesity (OSO) biomarkers, bone density and functional profile in women living with OSO syndrome. The eligible participants, aged 65 to 80 years, were selected by a physician. Accordingly, a total number of 63 women with OSO syndrome were recruited and assessed using a dual energy X-ray absorptiometry (DXA) instrument, body mass index (BMI) > 30 kg/m2, -2.5 ≤ T-score ≤ -1.0 of L1-L4, and/or total femur or femoral neck, and gait speed (10-meter walk test (10MWT)) ≤ 1 (m/s2). The 12-week supervised EBRT was designed to train all major muscle groups for 3 times per week. In the first two sessions, the participants became familiar with targeted number of repetitions (TNRs) and OMNI-resistance exercise scale (OMNI-RES) to control exercise intensity. Following an adaptation phase of 4 weeks (1 set of 12 rep) using low resistance (yellow Thera-Band), exercise intensity progressively increased by adapting the resistance of the elastic band (based on the Thera-Band® force-elongation table) from yellow to red and further to black. The participants in the control group also received telephone contacts or face-to-face interviews on a weekly basis to maintain their typical diet and activity habits. A two-way repeated measures ANOVA was employed to determine the main changes (2 times×2 groups) after 12 weeks of training. Partial eta-squared (ηp2) was additionally used to determine ES in ANOVA tests. At all the stages of data analysis in this RCT, intention-to-treat (ITT) analysis was performed. The results of two-way ANOVA showed significant elevations in E2 (F = 7.881, p = 0.006, ES = 0.079), MQ (F = 4.225, p = 0.043, ES = 0.044), OSO Z-score (F = 7.091, p = 0.030, ES = 0.069), 30-s chair stand test (F = 4.599, p = 0.036, ES = 0.063) and hand grip strength (F = 6.411, p = 0.013, ES = 0.065) in the experimental group compared with those in the controls. Besides, there were no significant differences in CAF (F = 0.456, p = 0.501, ES = 0.005), CTX-I (F = 3.427, p = 0.067, ES = 0.036), adiponectin (F = 2.733, p = 0.102, ES = 0.029), sTnT (F = 3.245, p = 0.075, ES = 0.034), sclerostin (F = 2.927, p = 0.091, ES = 0.034), gait speed (10MWT) (F = 1.524, p = 0.220, ES = 0.016), 6MWT (F = 1.169, p = 0.284, ES = 0.017) and TUG (F = 1.502, p = 0.225, ES = 0.022), BMI (F = 0.354, p = 0.553, ES = 0.004), BFP (F = 2.888, p = 0.093, ES = 0.030), body mass content (BMC) (F = 0.030, p = 0.862, ES = 0.001) and BMD (F = 0.335, p = 0.564, ES = 0.004) between study groups. Taken together, the results of this study illustrated significant differences only in some OSO markers between groups after 48 h of chronic EBRT in women affected with OSO syndrome. Further research is thus recommended to design machine-based and elastic band-based training regimes at different intensities and volumes.

4.
Res Pharm Sci ; 14(5): 414-423, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31798658

RESUMO

The main purpose of this study was to investigate the effects of elastic resistance band training (ERBT) and green coffee bean extract (GCBE) supplement on novel cardiometabolic indices in obese women. To this end, a total number of 60 obese women aged 30-50 years with a body mass index of > 30 kg/m2 were selected for inclusion in this study and then they were randomly assigned to one of the following four groups: placebo (n = 15), GCBE supplement (n = 15), GCBE supplement + ERBT (n = 15), and placebo + ERBT (n = 15). Each commercially prepared GCBE supplement capsule used in this study contained 500 mg of GCBE supplement and it was also claimed by the manufacturer to have 50% chlorogenic acid (CGA) (250 mg). The participants in the placebo + ERBT and GCBE supplement + ERBT groups attended an 8-week ERBT program, 3 sessions / week, and 60 min each session. In the GCBE supplement + ERBT group, Framingham risk score (P = 0.018), atherogenic index of plasma (P = 0.003), and metabolic syndrome severity score (P = 0.001) significantly decreased. Taken together, the results of the present study supported the importance of supplemental and resistance-type training in improving obesity and novel cardiometabolic risk scores, despite the fact that longer nutritional and exercise interventions could enhance some cardiometabolic risk scores in obese women.

5.
Invest Educ Enferm ; 37(2)2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31487442

RESUMO

OBJECTIVES: This work sought to determine the effectiveness of an aerobic exercise program on the occupational stress of nurses. METHODS: Prevention-type controlled clinical trial carried out with the participation of 60 nurses working in hospitals affiliated to Shahrekord University of Medical Sciences in Iran. Randomly, the nurses were assigned to the experimental group or to the control group. The intervention consisted in an aerobic exercise program lasting three months with three weekly sessions one hour each. The Health and Safety Executive (HSE) questionnaire measured occupational stress with 35 questions, each with five Likert-type response options, which can have a maximum score of 175 points; higher scores meant lower levels of occupational stress. The HSE was evaluated during three moments: upon registering, after finishing the exercise program (week 8), and two months after terminating the intervention (week 16). RESULTS: The level of occupational stress was the same in the experimental and control groups during registration (86.2 vs. 86.3). Upon finishing the aerobic exercise program (week 8), the experimental group showed a higher score than the control group (119.7 vs. 86.2, p<0.01), with this score diminishing after two months of having ended the intervention (91.4 vs. 85.8, p=0.061). CONCLUSIONS: The aerobic exercise program was associated to decreased work stress of nurses in the experimental group compared to the control group at eight weeks, but this difference did not persist when the experimental group did not continue with the program.


Assuntos
Exercício Físico/fisiologia , Recursos Humanos de Enfermagem no Hospital/psicologia , Estresse Ocupacional/prevenção & controle , Adulto , Feminino , Humanos , Irã (Geográfico) , Inquéritos e Questionários , Fatores de Tempo
6.
Invest. educ. enferm ; 37(2): [E05], 15-06-2019. Diag 1, Tab 1, Tab 2
Artigo em Inglês | LILACS, BDENF - Enfermagem, COLNAL | ID: biblio-1007512

RESUMO

Abstract Objective. This work sought to determine the effectiveness of an aerobic exercise program on the occupational stress of nurses. Methods. Prevention-type controlled clinical trial carried out with the participation of 60 nurses working in hospitals affiliated to Shahrekord University of Medical Sciences in Iran. Randomly, the nurses were assigned to the experimental group or to the control group. The intervention consisted in an aerobic exercise program lasting three months with three weekly sessions one hour each. The Health and Safety Executive (HSE) questionnaire measured occupational stress with 35 questions, each with five Likert-type response options, which can have a maximum score of 175 points; higher scores meant lower levels of occupational stress. The HSE was evaluated during three moments: upon registering, after finishing the exercise program (week 8), and two months after terminating the intervention (week 16). Results. The level of occupational stress was the same in the experimental and control groups during registration (86.2 vs. 86.3). Upon finishing the aerobic exercise program(week 8), the experimental group showed a higher score than the control group (119.7 vs. 86.2, p<0.01), with this score diminishing after two months of having ended the intervention (91.4 vs. 85.8, p=0.061). Conclusion. The aerobic exercise program was associated to decreased work stress of nurses in the experimental group compared to the control group at eight weeks, but this difference did not persist when the experimental group did not continue with the program.


Resumen Objetivo. Determinar la efectividad de un programa de ejercicio aeróbico en el estrés ocupacional de las enfermeras. Métodos. Ensayo clínico controlado de tipo preventivo que se llevó a cabo con la participación de 60 enfermeras que trabajaban en hospitales afiliados a Shahrekord University of Medical Sciences en Irán. Las enfermeras se asignaron aleatoriamente al grupo experimental o al grupo control. La intervención consistió en un programa de ejercicio aeróbico realizado durante dos meses con tres sesiones semanales de una hora de duración. El estrés ocupacional se midió con el cuestionario Health and Safety Executive (HSE) de 35 preguntas, con opciones de respuesta tipo Likert que van de 1 a 5; puede llegar a puntuar en 175 como máximo: a mayor puntaje, menor el nivel de estrés ocupacional. Se evaluó el HSE en tres momentos: en la inscripción, después de finalizar el programa de ejercicio (semana 8) y también dos meses después de terminada la intervención (semana 16). Resultados. Fue igual el nivel de estrés ocupacional en los grupos de intervención y de control en la inscripción (86.2 vs. 86.3), pero al finalizar el programa de ejercicios aeróbicos (semana 8) el grupo experimental mostró un puntaje mayor que el del grupo control (119.7 vs. 86.2, p<0.01), para luego disminuir este puntaje a los dos meses de haber finalizado la intervención, (91.4 vs. 85.8, p=0.061). Conclusión. El programa de ejercicio aeróbico se asoció a la disminución del estrés laboral de las enfermeras en el grupo de intervención en comparación con el grupo control a las ocho semanas, pero esta diferencia no se mantuvo cuando el grupo experimental no continuó con el programa.


Resumo Objetivo. Determinar a efetividade de um programa de exercício aeróbico sobre o estresse ocupacional das enfermeiras. Métodos. Ensaio clínico controlado de tipo preventivo que se levou a cabo com a participação de 60 enfermeiras que trabalhavam em hospitais afiliados a Shahrekord University of Medical Sciences no Irã. Em forma aleatorizada, as enfermeiras foram designadas ao grupo experimental ou ao grupo controle. A intervenção consistiu num programa de exercício aeróbico realizado durante dois meses com três sessões semanais de uma hora de duração. O estresse ocupacional se mediu com o questionário Health and Safety Executive (HSE) de 35 perguntas, que tem opções de resposta tipo Likert que vão de 1 a 5, pode chegar a pontuação de 175 como máximo; a maior pontuação, é menor o nível de estresse ocupacional. Se avaliou o HSE em três momentos: a inscrição, depois de finalizar o programa de exercício (semana 8) e também dois meses depois de terminada a intervenção (semana 16). Resultados. Foi igual o nível de estresse ocupacional nos grupos de intervenção e de controle na inscrição (86.2 vs. 86.3), mas ao finalizar o programa de exercícios aeróbicos (semana 8) o grupo experimental mostrou uma pontuação maior que o do grupo controle (119.7 vs. 86.2, p<0.01), para depois diminuir esta pontuação aos dois meses de haver finalizado a intervenção, (91.4 vs. 85.8, p=0.061). Conclusão. O programa de exercício aeróbico se associou à diminuição do estresse profissional das enfermeiras no grupo de intervenção em comparação com o grupo de controle às oito semanas, mas esta diferença não se manteve quando o grupo experimental não continuou com o programa.


Assuntos
Humanos , Grupos Controle , Esforço Físico , Estresse Ocupacional , Enfermeiros
7.
Clin Mol Hepatol ; 25(3): 294-304, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31142104

RESUMO

BACKGROUND/AIMS: Fatty liver is a clinical and pathologic condition in individuals with type 2 diabetes (T2D). The purpose of this study is to examine the effects of different exercise modalities on non-alcoholic fatty liver indices (fatty liver index [FLI], lipid accumulation product [LAP], hepatic steatosis index [HSI], and Framingham Steatosis Index [FSI]) in women with T2D. METHODS: Fifty-two women with T2D and a mean age of 55.07±5.92 yrs, body mass index (BMI) 28.94±4.09 kg/m2 , and hemoglobin A1c (HbA1c) 9.41±0.82% were randomized to a sprint interval training (SIT) (n=17), combined aerobic and resistance (A+R) training (n=17), or control group (n=18) for 10 weeks. Two-way repeated analysis of variance (ANOVA) was used to find differences between groups and the effects of time and Time×Group interactions after 10 weeks on non-alcoholic fatty liver indices. After this, ANOVA models were constructed to determine the effects of group allocation and change in non-alcoholic fatty liver indices. RESULTS: There were significant time interactions for FLI (P<0.001), HSI (P<0.001), and LAP (P<0.001). Also, there were significant Time×Group interactions for fasting blood glucose (P=0.034), and HbA1c (P=0.006). CONCLUSION: Results highlight that exercise training, independent of mode of training, is an effective strategy to improve some indices related to hepatic steatosis and blood glucose profiles in women with T2D.

8.
Horm Mol Biol Clin Investig ; 38(2)2019 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-31063458

RESUMO

Background Skeletal muscle is very sensitive to extracellular and intracellular signaling evoked by contractions from endurance and resistance exercise. The aim of this study was to compare the effects of moderate- and high-intensity endurance and resistance training on the serum myostatin (MSTN) and insulin-like growth factor (IGF-1) levels in older rats. Materials and methods Fifty old Wistar male rats (23 months old) were randomly divided into four experimental and one control groups, including moderate-endurance training (MET) (n = 10), high-intensity endurance training (EHT) (n = 10), moderate-intensity resistance training (MRT) (n = 10), high-intensity resistance training (HRT) (n = 10), and control group (C) (n = 10). Seventy-two hours after the last exercise session, euthanasia of the rats were rendered unconscious and direct blood samples were collected. Serum IGF-1 and MSTN concentration were measured using the enzyme-linked immuno sorbent assay (ELISA) method. The statistical analysis was performed using one-way analysis of variance (ANOVA) test with a significance level of p ≤ 0.05. Results There was a significant reduction in MSTN and an increase in IGF-1 concentrations was observed between IGF-I levels in high and moderate resistance and endurance training. However, no significant difference was observed in MSTN levels between groups. Discussion Therefore, it appears that resistance training, especially HRT, is effective to increase growth mediators among older rats.


Assuntos
Fator de Crescimento Insulin-Like I/metabolismo , Miostatina/sangue , Condicionamento Físico Animal , Animais , Masculino , Contração Muscular , Ratos , Ratos Wistar
9.
Mol Biol Rep ; 46(2): 2513-2521, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30915688

RESUMO

Bone tissue is known as a living dynamic and complex organ in response to physical activity and mechanical loading such as exercise training; thus, the purpose of this study was to determine the effect of different intensities of strength and endurance training on expression of some osteometabolic miRNAs and runt-related transcription factor 2 (Runx2) and peroxisome proliferator-activated receptor γ (PPARγ) in bone marrow of old male Wistar rats. To this end, a total number of 50 male Wistar rats (aged 23 months, 438.27 g) were obtained from Pasteur Institute of Iran. The rats were randomized into five groups (10 rats/per group) including moderate endurance training (MET), high-intensity endurance training (HET), moderate-intensity resistance training (MRT), high-intensity resistance training (HRT), and control (CON). The four training groups completed 8 weeks of a training program, 5 days a week, according to the study protocol. To evaluate miR-133a, miR-103a, miR-204, and other adipogenic and osteogenic genes such as RUNX2 and PPARγ via real-time PCR, total RNA including mRNA and miRNA was isolated from the bone marrow. The statistical analysis was then performed using two-way analysis of variance (ANOVA). No significant differences in miR-133a (p = 0.197), miR-103a (p = 0.302), miR-204 (p = 0.539), RUNX2 (p = 0.960), and PPARγ (P = 0.872) were observed between the intervention groups and the control one. Furthermore, there were no significant differences in bone force (p = 0.641), fracture energy (p = 0.982), stress (p = 0.753), module (p = 0.147), and elongation (p = 0.292) variables between the intervention groups and the control group. Investigating molecular and cellular changes in the bone after such exercises in longer time could provide clearer results about the beneficial or harmful effects of these types of exercises in healthy and passive elderly people.


Assuntos
Medula Óssea/fisiologia , Condicionamento Físico Animal/métodos , Condicionamento Físico Animal/fisiologia , Adipogenia , Fatores Etários , Animais , Osso e Ossos/metabolismo , Diferenciação Celular/efeitos dos fármacos , Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo , Treino Aeróbico/métodos , Irã (Geográfico) , Masculino , Células-Tronco Mesenquimais/efeitos dos fármacos , MicroRNAs/genética , Osteogênese/genética , Osteogênese/fisiologia , PPAR gama/metabolismo , RNA Mensageiro , Ratos , Ratos Wistar , Treinamento de Resistência/métodos
10.
Life Sci ; 217: 101-109, 2019 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-30508516

RESUMO

Our primary aim was to assess the effects of two different training modalities: sprint interval training (SIT) or combined aerobic and resistance training (A + R) on circulating myokines related to metabolic profile and adiposity in type 2 diabetes (T2D). Fifty-two overweight women with T2D [55 ±â€¯6 yrs., BMI 28.9 ±â€¯4.1 kg/m2, HbA1c 9.4 ±â€¯0.82% (79 mmol/mol)] were randomized to SIT (n = 17), A + R training (n = 17) or control (n = 18) for 10 weeks. Myokines, metabolic outcomes, body composition and cardiorespiratory fitness were assessed at baseline and 48 hours after the last training session/control period. Relationships between myokines and other variables were investigated via linear regression models. Completion rate was 81%. There was no effect of either exercise modality on any myokine. Interlukin-15 decreased over time irrespective of group assignment (p = 0.02). Aerobic capacity (p = 0.01), fasting glucose (p = 0.03) and HbA1c (p = 0.006) improved significantly and similarly in both exercise groups compared to controls. Insulin (p = 0.02), weight (p = 0.020, body max index (BMI) (p = 0.01) decreased significantly over time irrespective of group. Changes in myokines were unrelated to changes in body composition or metabolic profile. Neither SIT or A + R training altered myokines measured 48 h after exercise in T2D, despite improving aerobic capacity and glucose homeostasis relative to controls. Future studies are needed to elucidate the time course and clinical relevance of putative myokine responses to exercise in this and other cohorts.


Assuntos
Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/terapia , Terapia por Exercício/métodos , Treinamento Intervalado de Alta Intensidade/métodos , Sobrepeso/sangue , Sobrepeso/terapia , Treinamento de Resistência/métodos , Proteína 4 Semelhante a Angiopoietina/sangue , Composição Corporal , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/metabolismo , Exercício Físico , Tolerância ao Exercício , Feminino , Fatores de Crescimento de Fibroblastos/sangue , Fibronectinas/sangue , Humanos , Interleucina-15/sangue , Interleucina-6/sangue , Metaboloma , Pessoa de Meia-Idade , Osteonectina/sangue , Sobrepeso/complicações , Sobrepeso/metabolismo
11.
Horm Mol Biol Clin Investig ; 35(3)2018 Sep 08.
Artigo em Inglês | MEDLINE | ID: mdl-30205658

RESUMO

Background Physiological aging can now be considered as a multi-factorial process that is associated with anatomical and signaling changes associated with endocrine function. The purpose of this study was to investigate the comparison of performing 12 weeks' resistance training before, after and/or in between aerobic exercise on the hormonal status of aged women. Materials and methods Forty healthy aged women (age: 67.35 ± 1.40 years) were randomly divided into three training groups and a control group: resistance followed by endurance training (ER, n = 12), endurance training followed by resistance training (RE, n = 12, interval resistance-endurance (RE) training (INT, n = 12) and a control (Con, n = 12) groups. The training program was done over 12 weeks, 3 times per week. Endurance training was performed on a cycle ergometer (intensity: 60-90% maximum heart rate) and resistance training involved selected resistance exercises (intensity: 40-75 one-repetition maximum, 8-18 repeats). All participants were evaluated before and after the training period. Results and conclusion The data showed that performing resistance training before, after and/or in between aerobic exercise did not influence the adaptive response of insulin like growth factor-1 (IGF-1) (p = 0.07), growth hormone (p = 0.35), cortisol (p = 0.20), insulin (p = 0.72), epinephrine (p = 0.83) and norepinephrine (p = 0.86) levels throughout the study. However, when comparing pre and post, no significant differences were shown following combined training within the SE, ES and INT groups for all variables (p < 0.05), except of IGF-1 within ES (p = 0.04) and SE (p = 0.02), and testosterone within ES (p = 0.007). In conclusion, combined training with RE order may be more effective than other orders for increasing anabolic status in aged women.


Assuntos
Exercício Físico , Hormônios/sangue , Treinamento de Resistência/métodos , Idoso , Epinefrina/sangue , Feminino , Hormônio do Crescimento/sangue , Humanos , Hidrocortisona/sangue , Insulina/sangue , Fator de Crescimento Insulin-Like I/análise , Norepinefrina/sangue
12.
J Sports Med Phys Fitness ; 56(4): 476-82, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25651894

RESUMO

BACKGROUND: Omentin, chemerin and vaspin are novel adipokines that are secreted from adipose tissue and improved insulin sensitive. The purpose of this study was to examine the effects of rhythmic aerobic exercise plus core stability training on serum omentin, chemerin and vaspin levels and insulin resistance (IR) of overweight women. METHODS: Forty aged healthy women (age; 25-45 years old, waist circumference [WC]>88 cm; Body Mass Index (BMI)>25 kg/m2) were selected purposely and divided in two control (N.=16) and experimental (N.=19) groups. Five dropped out during the study. The experimental group trained 12 weeks (3 sessions per week, one hr/session). The exercise program consisted of rhythmic aerobic exercise (55-85% maximum heart rate) along with core stability training. Serum chemerin, omentin, vaspin and insulin concentration were assayed by commercially ELISA kit. IR was evaluated according to the Homeostasis Model Assessment of Insulin Resistance Index (HOMA-IR). Data were analyzed by dependent and independent t-test to compare pre-test and post-test in each group and to compare the amount of changes in experimental and control training groups after twelve weeks. RESULTS: The result showed that exercise training had significant effect on BMI (P=0.00), WC (P=0.00), body fat (P=0.05), chemerin (P=0.041) and vaspin (P=0.045). But, this training had non-significant effect on plasma omentin level (P=0.090), plasma glucose level (P=0.670), insulin (P=0.11) and IR (P=0.07). CONCLUSIONS: Despite the fact that this kind of intervention could be an effective treatment to improve some adipokine levels and was accompanied by decreased body fat and waist circumference. However, more intense training is required to significantly change IR and serum omentin level in overweight women.


Assuntos
Índice de Massa Corporal , Quimiocinas/sangue , Citocinas/sangue , Exercício Físico , Resistência à Insulina , Insulina/sangue , Peptídeos e Proteínas de Sinalização Intercelular/sangue , Lectinas/sangue , Sobrepeso/sangue , Serpinas/sangue , Tecido Adiposo , Adulto , Análise de Variância , Estudos de Casos e Controles , Ensaio de Imunoadsorção Enzimática , Feminino , Proteínas Ligadas por GPI/sangue , Humanos , Pessoa de Meia-Idade , Obesidade/sangue
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