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1.
Pediatr Cardiol ; 41(3): 561-575, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32107586

RESUMO

Aortic coarctation is a common congenital heart defect that often requires correction at a young age. Currently, success is defined by the achievement of a durable repair with low morbidity and mortality. We sought to systematically review the literature on risk factors for recoarctation and mortality in infants submitted to aortic arch coarctation repair under 1 year of age. PubMed and Scopus were searched for studies reporting risk factors for recoarctation and mortality from January 1989 to August 2019. Among the 1038 retrieved articles, 18 met the inclusion criteria, with a total of 2891 patients. The extracted risk factors for recoarctation were comprehensively summarized in the following categories: demographic variables, associated anomalies, clinical and repair variables, and morphometric variables. Younger age and lower weight were weak determinants of need for reintervention, while smaller aortic arch was a strong predictor of recoarctation. While balloon angioplasty is a clear risk factor for arch restenosis, the chosen surgical technique is not a strong risk factor. Associated minor cardiac anomalies and lower weight at surgery were important risk factors for death. Younger and smaller infants are at increased risk for adverse outcomes when submitted to aortic arch coarctation repair. This is particularly important when associated with smaller arch morphology. Strategies to improve the management of these patients may play a key role in improving their outcomes. Notably, surgical technique was not a strong predictor of recoarctation and mortality, suggesting that the choice of one over the other should be tailored.

2.
Sci Rep ; 10(1): 401, 2020 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-31942013

RESUMO

Horse flies (Diptera: Tabanidae) cause direct and indirect losses in livestock production and are important vectors of pathogens. The aim of this study was to determine the diversity and seasonality of horse fly species at an experimental farm in Tacuarembó and the diversity of species in different departments of Uruguay. For 20 months, systematic collections were performed in two different environments at the experimental farm using Nzi and Malaise traps. In addition, nonsystematic collections were performed at farms located in the departments of Paysandú, Tacuarembó and Colonia. A total of 3,666 horse flies were collected, and 16 species were identified. These species included three species that had not been previously recorded in Uruguay, namely, Dasybasis ornatissima (Brèthes), Dasybasis missionum (Macquart), and Tabanus aff. platensis Brèthes, and a species that had not been previously taxonomically described (Tabanus sp.1). Among the systematically captured samples, the most abundant species were Tabanus campestris Brèthes, T. aff. platensis and D. missionum, representing 77.6% of the collected specimens. The horse fly season in Tacuarembó started in September and ended in May. No horse flies were caught during winter. Variations in the prevalences of species in the different departments were observed, which indicates the need for new sampling efforts.

3.
Clin Res Cardiol ; 109(2): 194-204, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31250134

RESUMO

INTRODUCTION: After myocardial infarction complicated by heart failure or diabetes, eplerenone (compared to placebo) significantly decreases amino-terminal propeptide of type III procollagen (PIIINP). Determining the subset of patients who are more prone to have a decrease in PIIINP and those who may respond better to the anti-fibrotic effects of mineralocorticoid receptor antagonists (MRA) therapy may be relevant for a personalized treatment approach. The aim of this study is to identify predictors of a PIIINP decrease and assess potential subgroups of "responders" to eplerenone. METHODS: Clinical factors and biomarkers were evaluated as predictors of a PIIINP decrease from randomization to month 9 in 323 patients from the biomarker substudy of Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS). Additionally, the association between PIIINP decrease and the composite of cardiovascular (CV) death or CV hospitalization were also explored. External validation was performed in the REMINDER trial. RESULTS: Female sex, eplerenone, reperfusion therapy, potassium < 4 mmol/L, circulating levels of PIIINP ≥ 3.6 ng/mL and PINP ≥ 27 ng/mL predicted a PIIINP decrease (AUC = 0.75). Randomization PIIINP showed a significant interaction with the treatment allocation: patients with PIIINP ≥ 3.6 ng/mL had a better response (decrease in PIIINP) to eplerenone (OR for PIIINP ≥ 3.6 = 2.9, 95% CI 1.46-5.89, p = 0.003) and OR for PIIINP < 3.6 = 1.09, 95% CI 0.55-2.2, p = 0.8; interactionp = 0.026). These findings were internally robust using another statistical approach (LOESS). External validation showed good discrimination (AUC = 0.70). There was a tendency toward a lower rate of CV death/CV hospitalizations in patients with decreased PIIINP (adjusted HR = 0.52, 95% CI 0.26-1.02, p = 0.058). CONCLUSION: In patients who had a myocardial infarction, clinical factors used in combination and treatment with eplerenone were associated with a PIIINP decrease. Interestingly, higher randomization PIIINP levels might help in identifying patients more prone to have an "anti-fibrotic response" when treated with MRAs. Predictors of an antifibrotic response after MI complicated by HF. Several clinical factors and biomarkers predicted a PIIINP decrease after an MI complicated by HF. There was a significant interaction between baseline PIIINP levels and eplerenone treatment: patients with baseline PIIINP ≥ 3.6 mmol/L treated with eplerenone had the best response (PIIINP decrease).

4.
J Environ Manage ; 255: 109850, 2020 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-31760299

RESUMO

This work investigated the effect of Ca2+ (100 mg L-1) addition on the formation and maintenance of aerobic granular sludge in a simultaneous fill/draw mode sequencing batch reactor (SBR), operated with a low liquid upflow velocity (0.92 m h-1), in order to verify if Ca2+ presence compensates the low selection pressure imposed. Additionally, carbon and nutrients removals, granules characteristics and microbial community were evaluated. For this, two SBRs (R1, control, and R2, Ca2+-supplemented) were operated (6-h cycle). In general, Ca2+ supplementation affected positively the sludge settleability, although a larger fraction of inert solids was found in the granules. The total extracellular polymeric substances were the same for both reactors, and no remarkable differences were observed between their polysaccharides and proteins contents. Overall, Ca2+ addition in a simultaneous fill/draw mode SBR neither accelerated the granule formation nor improved the operational performance. The microbial community structure, especially in terms of bioactivity, was not affected as well. Therefore, the effect of divalent cations might be more pronounced in conventional SBRs, in which the selection pressure is higher.


Assuntos
Esgotos , Eliminação de Resíduos Líquidos , Aerobiose , Reatores Biológicos , Cálcio
5.
Atherosclerosis ; 292: 75-83, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31783201

RESUMO

BACKGROUND & AIMS: The role of epicardial adipose tissue (EAT) in the pathophysiology of late stage-coronary artery disease (CAD) has not been investigated. We explored the association of EAT volume and its proteome with advanced coronary atherosclerosis. METHODS: The EPICHEART Study prospectively enrolled 574 severe aortic stenosis patients referred to cardiac surgery. Before surgery, EAT volume was quantified by computed tomography (CT). During surgery, epicardial, mediastinal (MAT) and subcutaneous (SAT) adipose tissue samples were collected to explore fat phenotype by analyzing the proteomic profile using SWATH-mass spectrometry; pericardial fluid and peripheral venous blood were also collected. CAD presence was defined as coronary artery stenosis ≥50% in invasive angiography and by CT-derived Agatston coronary calcium score (CCS). RESULTS: EAT volume adjusted for body fat was associated with higher CCS, but not with the presence of coronary stenosis. In comparison with mediastinal and subcutaneous fat depots, EAT exhibited a pro-calcifying proteomic profile in patients with CAD characterized by upregulation of annexin-A2 and downregulation of fetuin-A; annexin-A2 protein levels in EAT samples were also positively correlated with CCS. We confirmed that the annexin-A2 gene was overexpressed in EAT samples of CAD patients and positively correlated with CCS. Fetuin-A gene was not detected in EAT samples, but systemic fetuin-A was higher in CAD than in non-CAD patients, suggesting that fetuin-A was locally downregulated. CONCLUSIONS: In an elderly cohort of stable patients, CCS was associated with EAT volume and annexin-A2/fetuin-A signaling, suggesting that EAT might orchestrate pro-calcifying conditions in the late phases of CAD.

6.
Rev. bras. parasitol. vet ; 28(4): 548-562, Oct.-Dec. 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1057986

RESUMO

Abstract Cochliomyia hominivorax (Coquerel, 1858), the New World screwworm, causes primary myiasis in wild and domestic animals in tropical and subtropical regions of Brazil. Although this species is considered to occur throughout the country, organized information about its recorded distribution has not been available until now. This article aimed to provide a comprehensive review of the historical and current data published on both immature (myiasis) and adult stages of C. hominivorax in Brazil. A total of 174 articles were found; of these, 141 articles reported myiasis cases in cattle (146 records), humans (68 records), and other mammalian hosts (40 records), and captures of adult flies were reported in 33 articles. C. hominivorax is widespread in Brazil, having been recorded in 208 municipalities in all major biomes of the country.


Resumo Cochliomyia hominivorax (Coquerel, 1858), a mosca-da-bicheira, causa miíase primária em animais silvestres e domésticos em regiões tropicais e subtropicais do Brasil. Embora esta espécie seja considerada de ocorrência em todo o país, informações organizadas sobre sua distribuição com base em registros não estavam disponíveis até o momento. Este artigo teve como objetivo fornecer uma revisão abrangente dos dados históricos e atuais publicados sobre o registro de estágios imaturos (miíase) e adultos de C. hominivorax, no Brasil. De 174 artigos encontrados, 141 relataram casos de miíase em bovinos (146 relatos), humanos (68 relatos) e outros mamíferos hospedeiros (40 relatos) e capturas de adultos de C. hominivorax foram registradas em 33 artigos. C. hominivorax encontra-se amplamente distribuída no Brasil, tendo sido registrada em 208 municípios brasileiros em todos os principais biomas do país.

7.
Rev. bras. parasitol. vet ; 28(4): 802-806, Oct.-Dec. 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1057988

RESUMO

Abstract Population explosions of the stable fly (Stomoxys calcitrans) have become a serious concern for livestock producers near sugarcane mills in some regions of Brazil due to the insect's massive reproduction on sugarcane byproducts and waste. Despite the limited efficiency of insecticides for controlling stable fly outbreaks, producers still rely on chemical control to mitigate the alarming infestations in affected areas. This study evaluated the susceptibility of S. calcitrans populations to cypermethrin in the state of Mato Grosso do Sul, Brazil. Stable flies were tested from three field populations and two colonies, established from flies previously collected at sugarcane mills. Wild flies were collected with Nzi traps in areas of sugarcane plantations. Both wild and colonized flies were exposed to eleven concentrations of cypermethrin in impregnated filter paper bioassays. All the populations proved to be resistant to cypermethrin, with resistance factors among field populations ranging from 6.8 to 38.6. The intensive use of insecticides has led to the development of pyrethroid resistance in stable fly populations in the proximities of sugarcane mills in the state of Mato Grosso do Sul.


Resumo Explosões populacionais da mosca-dos-estábulos (Stomoxys calcitrans) tornaram-se uma séria preocupação para a pecuária próxima a usinas de cana-de-açúcar em algumas regiões do Brasil, devido à massiva reprodução da mosca em resíduos e subprodutos do processamento da cana. Apesar da limitada eficiência dos inseticidas no controle dos surtos desta mosca, produtores dependem do controle químico para mitigar as alarmantes infestações nas áreas afetadas. Este estudo objetivou avaliar a suscetibilidade de populações de S. calcitrans a piretroides no estado de Mato Grosso do Sul, Brasil. Moscas-dos-estábulos de três populações de campo e duas colônias, estabelecidas a partir de moscas previamente coletadas em usinas de cana-de-açúcar, foram testadas. Moscas selvagens foram coletadas com armadilhas Nzi em áreas de cana. Moscas coletadas foram expostas a onze concentrações de cipermetrina em bioensaios com papel de filtro impregnado. Todas as populações testadas mostraram-se resistentes ao piretroide, com fatores de resistência variando de 6,8 a 38,6 nas populações de campo. O uso intensivo de inseticidas tem levado ao desenvolvimento de resistência da mosca-dos-estábulos a piretroides em populações próximas a usinas de cana-de-açúcar no estado do Mato Grosso do Sul.

8.
Rev Bras Parasitol Vet ; 28(4): 802-806, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31691737

RESUMO

Population explosions of the stable fly (Stomoxys calcitrans) have become a serious concern for livestock producers near sugarcane mills in some regions of Brazil due to the insect's massive reproduction on sugarcane byproducts and waste. Despite the limited efficiency of insecticides for controlling stable fly outbreaks, producers still rely on chemical control to mitigate the alarming infestations in affected areas. This study evaluated the susceptibility of S. calcitrans populations to cypermethrin in the state of Mato Grosso do Sul, Brazil. Stable flies were tested from three field populations and two colonies, established from flies previously collected at sugarcane mills. Wild flies were collected with Nzi traps in areas of sugarcane plantations. Both wild and colonized flies were exposed to eleven concentrations of cypermethrin in impregnated filter paper bioassays. All the populations proved to be resistant to cypermethrin, with resistance factors among field populations ranging from 6.8 to 38.6. The intensive use of insecticides has led to the development of pyrethroid resistance in stable fly populations in the proximities of sugarcane mills in the state of Mato Grosso do Sul.


Assuntos
Inseticidas/farmacologia , Muscidae/efeitos dos fármacos , Piretrinas/farmacologia , Animais , Bioensaio , Brasil , Resistência a Inseticidas , Dose Letal Mediana
9.
Biosci. j. (Online) ; 35(5): 1390-1398, sept./oct. 2019. graf, tab
Artigo em Inglês | LILACS | ID: biblio-1048946

RESUMO

Tabanid (Diptera) species are associated with the mechanical transmission of several pathogens to both domestic and wild animals around the world. The aim of this study was to evaluate the diversity, abundance, and seasonal dynamic of tabanids in the Cerrado-Pantanal ecotone in Miranda, state of Mato Grosso do Sul, Brazil. Tabanids were collected once a month, from June 2001 to May 2003, for seven consecutive days per collection, using canopy and nzi type traps baited with a chemical attractant (1-octen-3-ol). A total of 6,492 individuals from 39 species and 18 genera was collected, which increases from 25 to 34 the number of tabanid species reported for the studied region. Tabanus occidentalis Linnaeus, 1758 (62.21%) was the most abundant species throughout the collection period, followed by Lepiselaga crassipes (Fabricius, 1805) (7.19%) and Tabanus sorbillans Wiedemann, 1828 (5.68%). The peak of the tabanid population was reached during the rainy season, which is the period of the highest potential risk of mechanical transmission of pathogens by these insects in the studied region.


Tabanídeos (Diptera) são importantes vetores de patógenos a animais domésticos e silvestres no mundo. O objetivo foi estudar a diversidade, abundância e dinâmica sazonal de Tabanidae no ecótono Cerrado-Pantanal em Miranda, Mato Grosso do Sul, Brasil. Uma captura foi realizada por mês cada por sete dias consecutivos de junho 2001 a maio 2003 utilizando armadilhas modelo canopy e nzi. As armadilhas foram iscadas com o atrativo químico "1-octen-3-ol". Um total de 6.491 tabanídeos, de 39 espécies e 18 gêneros, foi capturado, ampliando a lista de espécies de tabanídeos relatados para o Mato Grosso do Sul de 25 para 34. Tabanus occidentalis Linnaeus, 1758 (62,21%) foi o mais abundante durante o período de coleta, seguido por Lepiselaga crassipes (Fabricius, 1805) (7,19%) e Tabanus sorbillans Wiedemann, 1828 (5,68%). A maioria das espécies de tabanídeos teve pico populacional durante o período chuvoso, considerado o de maior risco potencial de transmissão mecânica de patógenos por estes vetores na região estudada.


Assuntos
Dípteros , Áreas Alagadas
10.
Rev Bras Parasitol Vet ; 28(4): 548-562, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31483031

RESUMO

Cochliomyia hominivorax (Coquerel, 1858), the New World screwworm, causes primary myiasis in wild and domestic animals in tropical and subtropical regions of Brazil. Although this species is considered to occur throughout the country, organized information about its recorded distribution has not been available until now. This article aimed to provide a comprehensive review of the historical and current data published on both immature (myiasis) and adult stages of C. hominivorax in Brazil. A total of 174 articles were found; of these, 141 articles reported myiasis cases in cattle (146 records), humans (68 records), and other mammalian hosts (40 records), and captures of adult flies were reported in 33 articles. C. hominivorax is widespread in Brazil, having been recorded in 208 municipalities in all major biomes of the country.


Assuntos
Dípteros/classificação , Infecção por Mosca da Bicheira/epidemiologia , Animais , Brasil/epidemiologia , Bovinos , Geografia , Humanos , Prevalência , Infecção por Mosca da Bicheira/veterinária
11.
Rev Bras Parasitol Vet ; 28(3): 465-472, 2019 Aug 29.
Artigo em Inglês | MEDLINE | ID: mdl-31483037

RESUMO

To identify susceptible and resistant Haematobia irritans cows, horn flies were counted biweekly for 3 years in a herd of 25 Sindhi cows. Repeated measures linear mixed models were created including cow as a random factor. The results were analyzed by: 1) observing horn fly counts, considering fly-susceptible cows with infestations appearing in the upper quartile more than 50% of the weeks and in the lower quartile less than 20% of the weeks, and fly-resistant cows those that the number of flies was in the lower quartile more than 50% of the weeks and in the upper quartile less than 20%; 2) by the best linear unbiased predictions (BLUPs), to evaluate the cow effect on fly counts. Fly-susceptible cows were those in which the infestation appeared in the 90th percentile of the BLUPs, whereas fly-resistant cows appeared in the 10th percentile. For the observational method the individuals identified as resistant varied between 8% and 20% and 8% to 12% were susceptible. For the BLUP method, the rates of susceptible and resistant cows were 12%. The agreement among methods suggests that susceptible cows can be identified by observations of fly counts, allowing for selective breeding, culling or treatment.


Assuntos
Doenças dos Bovinos/parasitologia , Suscetibilidade a Doenças , Ectoparasitoses/veterinária , Muscidae , Animais , Bovinos , Estações do Ano
12.
Rev Bras Ortop (Sao Paulo) ; 54(2): 214-218, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31363271

RESUMO

Primary pyomyositis is a deep bacterial infection of the skeletal muscle. If left undiagnosed and untreated, the infection spreads, leading to sepsis, septic shock, and even death. The authors report a 23-year-old female presenting with piriformis pyomyositis during a treatment for Kikuchi-Fujimoto disease. Pyomyositis is a rare but potentially severe infection, which can lead to septic shock. The present case shows the need for a high degree of clinical suspicion for patients with compromised immune systems to begin treatment at an early stage. The literature demonstrates that outcomes of the treatment of piriformis pyomyositis are good.

13.
Radiol Bras ; 52(4): 237-241, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31435084

RESUMO

Objective: To determine the size of the ischiofemoral space (IFS) and quadratus femoris space (QFS) in patients with and without ischiofemoral impingement (IFI). Materials and Methods: Case-control study including consecutive patients submitted to magnetic resonance imaging (MRI) of the hip joint during a three-month period. Patients with deep gluteal pain who tested positive for IFI on at least one clinical test and showed signal changes in the quadratus femoris muscle on MRI were categorized as having a confirmed diagnosis of IFI. Results: Final sample comprised 50 patients submitted to unilateral MRI of the hip joint. The mean age was 47.3 ± 14.0 years (range, 22-76 years), and 33 (66%) of the patients were women. A diagnosis of IFI was made in 6 patients (12%), all of whom were female. On average, IFS and QFS were significantly smaller in IFI group than in control group (11.1 ± 2.7 mm versus 27.5 ± 6.5 mm and 5.3 ± 1.8 mm versus 18.8 ± 4.8 mm, respectively; p < 0.001 for both). Conclusion: Results of specific clinical tests and MRI findings indicate that the IFS and QFS are significantly reduced in patients with IFI.

14.
Rev Bras Ortop (Sao Paulo) ; 54(4): 440-446, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31435112

RESUMO

Objective To evaluate the inter- and intraobserver reliability of the Outerbridge, Beck, and Haddad classifications for acetabular joint cartilage lesions through the arthroscopic procedure. Methods A total of 60 hip arthroscopy videos were evaluated twice by 4 surgeons at 2 different times to assess the inter- and intraobserver reproducibility of the classifications, and the data was analyzed by means of the weighted Cohen Kappa index. Results The mean weighted Kappa values in the interobserver assessment of the Outerbridge, Beck, and Haddad classifications were, respectively, 0.72, 0.78, and 0.68. The three classifications were considered as presenting good interobserver agreement. Regarding the intraobserver assessment of the Outerbridge, Beck, and Haddad classifications, the weighted Kappa values were, respectively, 0.9, 0.9, and 0.93. The three classifications were considered as presenting excellent intraobserver agreement. Conclusion In the present series, the Outerbridge, Beck, and Haddad classifications presented good interobserver reproducibility and excellent intraobserver reproducibility when evaluating acetabular chondral lesions by the arthroscopic approach.

15.
Rev Bras Ortop (Sao Paulo) ; 54(4): 471-476, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31435117

RESUMO

Objective The objective of the present study is to evaluate the restoration capacity of the hip anatomic rotation center with the use of acetabular tantalum cups, associated or not with addition wedges. Methods Retrospective analysis of patients undergoing hip arthroplasty revision using tantalum between June 2013 and April 2017. The abduction angle of the acetabular component and the horizontal and vertical distances of the component to the center of anatomical rotation of the hip were evaluated. The measurements were made through baseline radiographs performed in the preoperative period and at the last follow-up visit. Results A sample of 21 patients was obtained, 11 (52%) men and 10 (48%) women, with a mean age of 62 ± 13 years old. The mean abduction angle of the acetabular cup decreased from 48.76° ± 13.88 ° in the preoperative period to 38.52° ± 10.08 ° in the postoperative period, and this difference was statistically significant ( p = 0.001). The distances from the center of rotation of the prosthesis relative to the center of anatomical rotation of the hip were also lower after revision surgery with tantalum. The mean horizontal distance of 12.74 ± 10.59 mm was reduced to 7.11 ± 4.84 mm, and the mean vertical distance was reduced from 14.79 ± 10.05 mm to 4.89 ± 6.21 mm, and these reductions were statistically significant ( p < 0.001). Conclusion Hip arthroplasty revision with tantalum cups, associated or not with addition wedges, significantly recovered the anatomical rotation center of the hip.

16.
Radiol. bras ; 52(4): 237-241, July-Aug. 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1020312

RESUMO

Abstract Objective: To determine the size of the ischiofemoral space (IFS) and quadratus femoris space (QFS) in patients with and without ischiofemoral impingement (IFI). Materials and Methods: Case-control study including consecutive patients submitted to magnetic resonance imaging (MRI) of the hip joint during a three-month period. Patients with deep gluteal pain who tested positive for IFI on at least one clinical test and showed signal changes in the quadratus femoris muscle on MRI were categorized as having a confirmed diagnosis of IFI. Results: Final sample comprised 50 patients submitted to unilateral MRI of the hip joint. The mean age was 47.3 ± 14.0 years (range, 22-76 years), and 33 (66%) of the patients were women. A diagnosis of IFI was made in 6 patients (12%), all of whom were female. On average, IFS and QFS were significantly smaller in IFI group than in control group (11.1 ± 2.7 mm versus 27.5 ± 6.5 mm and 5.3 ± 1.8 mm versus 18.8 ± 4.8 mm, respectively; p < 0.001 for both). Conclusion: Results of specific clinical tests and MRI findings indicate that the IFS and QFS are significantly reduced in patients with IFI.


Resumo Objetivo: Avaliar, prospectivamente, os valores médios dos espaços isquiofemoral e quadrado femoral em pacientes com impacto isquiofemoral e em um grupo controle. Materiais e Métodos: Estudo prospectivo incluindo pacientes submetidos a ressonância magnética da articulação do quadril em um intervalo de três meses. Os pacientes com dor glútea profunda, com pelo menos um teste clínico positivo para impacto isquiofemoral e alterações de sinal no músculo quadrado femoral na ressonância magnética, foram diagnosticados com impacto isquiofemoral. Resultados: A amostra final consistiu de 50 pacientes submetidos a ressonância magnética unilateral da articulação do quadril. A idade média foi 47,3 ± 14,0 anos (intervalo de 22 a 76 anos) e 33 (66%) eram mulheres. O diagnóstico de impacto isquiofemoral foi observado em 6 (12%) pacientes, todas mulheres. Os pacientes com impacto isquiofemoral mostraram redução significativa nos espaços isquiofemoral e quadrado femoral quando comparados ao grupo controle: 11,1 ± 2,7 mm versus 27,5 ± 6,5 mm e 5,3 ± 1,8 mm versus 18,8 ± 4,8 mm, respectivamente (p < 0,001 para ambos os grupos). Conclusão: Os pacientes com diagnóstico de impacto isquiofemoral apresentaram redução significativa dos espaços isquiofemoral e quadrado femoral após análise prospectiva baseada em testes clínicos específicos e ressonância magnética.

17.
Rev. bras. ortop ; 54(4): 440-446, July-Aug. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1042416

RESUMO

Abstract Objective To evaluate the inter- and intraobserver reliability of the Outerbridge, Beck, and Haddad classifications for acetabular joint cartilage lesions through the arthroscopic procedure. Methods A total of 60 hip arthroscopy videos were evaluated twice by 4 surgeons at 2 different times to assess the inter- and intraobserver reproducibility of the classifications, and the data was analyzed by means of the weighted Cohen Kappa index. Results The mean weighted Kappa values in the interobserver assessment of the Outerbridge, Beck, and Haddad classifications were, respectively, 0.72, 0.78, and 0.68. The three classifications were considered as presenting good interobserver agreement. Regarding the intraobserver assessment of the Outerbridge, Beck, and Haddad classifications, the weighted Kappa values were, respectively, 0.9, 0.9, and 0.93. The three classifications were considered as presenting excellent intraobserver agreement. Conclusion In the present series, the Outerbridge, Beck, and Haddad classifications presented good interobserver reproducibility and excellent intraobserver reproducibility when evaluating acetabular chondral lesions by the arthroscopic approach.


Resumo Objetivo Avaliar a confiabilidade inter- e intraobservador das classificações de Outerbridge, Beck e Haddad para lesões da cartilagem articular acetabular com o uso da via artroscópica. Métodos Foram avaliados 60 vídeos de artroscopias do quadril por 4 cirurgiões em 2 momentos para avaliar a reprodutibilidade inter- e intraobservador das classificações. Os dados foram analisados a partir do cálculo do índice Kappa de Cohen ponderado. Resultados Os valores do Kappa ponderado médio na avaliação interobservador das classificações de Outerbridge, Beck e Haddad foram, respectivamente, 0,72, 0,78 e 0,68. As três classificações foram consideradas como de boa concordância interobservador. Comrelação à avaliação intraobservador das classificações de Outerbridge, Beck e Haddad, os valores Kappa foram, respectivamente, 0,9, 0,9 e 0,93. As três classificações foram consideradas excelentes na comparação intraobservador. Conclusão Na presente série, as classificações de Outerbridge, Beck e Haddad apresentaram boa reprodutibilidade interobservador e excelente reprodutibilidade intraobservador ao avaliar lesões condrais acetabulares por via artroscópica.


Assuntos
Artroscopia , Doenças das Cartilagens/classificação , Reprodutibilidade dos Testes , Quadril
18.
Rev. bras. ortop ; 54(4): 471-476, July-Aug. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1042434

RESUMO

Abstract Objective The objective of the present study is to evaluate the restoration capacity of the hip anatomic rotation center with the use of acetabular tantalum cups, associated or not with addition wedges. Methods Retrospective analysis of patients undergoing hip arthroplasty revision using tantalum between June 2013 and April 2017. The abduction angle of the acetabular component and the horizontal and vertical distances of the component to the center of anatomical rotation of the hipwere evaluated. The measurements were made through baseline radiographs performed in the preoperative period and at the last follow-up visit. Results A sample of 21 patients was obtained, 11 (52%) men and 10 (48%) women, with amean age of 62 ± 13 years old. The mean abduction angle of the acetabular cup decreased from 48.76° ± 13.88 ° in the preoperative period to 38.52° ± 10.08 ° in the postoperative period, and this difference was statistically significant (p = 0.001). The distances from the center of rotation of the prosthesis relative to the center of anatomical rotation of the hip were also lower after revision surgery with tantalum. The mean horizontal distance of 12.74 ± 10.59 mm was reduced to 7.11 ± 4.84 mm, and the mean vertical distance was reduced from 14.79 ± 10.05 mm to 4.89 ± 6.21 mm, and these reductions were statistically significant (p < 0.001). Conclusion Hip arthroplasty revision with tantalum cups, associated or not with addition wedges, significantly recovered the anatomical rotation center of the hip.


Resumo Objetivo O objetivo do presente estudo é avaliar a capacidade de restauração do centro de rotação anatômico do quadril com uso de copas acetabulares de tântalo associado ou não a cunhas de adição. Métodos Análise retrospectiva dos pacientes submetidos a revisão de artroplastia do quadril comuso de tântalo entre o período de junho de 2013 e abril de 2017. Foramavaliados o ângulo de abdução do componente acetabular e as distâncias horizontal e vertical do componenteao centro de rotação anatômicodoquadril.Asmedidas foramrealizadas através de radiografias da bacia realizadas no pré-operatório e na última visita de seguimento. Resultados Obteve-se uma amostra de 21 pacientes, 11 (52%) homens e 10 (48%) mulheres, com média de idade de 62 ± 13 anos. O ângulo médio de abdução da copa acetabular reduziu de 48,76° ± 13,88° no pré-operatório para 38,52° ± 10,08° no pósoperatório, sendo esta diferença estatisticamente significativa (p = 0,001). As distâncias do centro de rotação da prótese em relação ao centro de rotação anatômico do quadril também foram menores após a cirurgia de revisão com o tântalo. A distância média horizontal de 12,74 ± 10,59 mm foi reduzida para 7,11 ± 4,84 mm, e a distância média vertical foi reduzida de 14,79 ± 10,05 mm para 4,89 ± 6,21 mm, sendo essas reduções estatisticamente significativas (p < 0,001). Conclusão As revisões de artroplastia do quadril comcopas de tântalo, associadas ou não a cunhas de adição, recuperaram de forma significativa o centro de rotação anatômico do quadril.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Tantálio , Artroplastia de Quadril , Acetábulo
19.
Rev. bras. parasitol. vet ; 28(3): 465-472, July-Sept. 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1042523

RESUMO

Abstract To identify susceptible and resistant Haematobia irritans cows, horn flies were counted biweekly for 3 years in a herd of 25 Sindhi cows. Repeated measures linear mixed models were created including cow as a random factor. The results were analyzed by: 1) observing horn fly counts, considering fly-susceptible cows with infestations appearing in the upper quartile more than 50% of the weeks and in the lower quartile less than 20% of the weeks, and fly-resistant cows those that the number of flies was in the lower quartile more than 50% of the weeks and in the upper quartile less than 20%; 2) by the best linear unbiased predictions (BLUPs), to evaluate the cow effect on fly counts. Fly-susceptible cows were those in which the infestation appeared in the 90th percentile of the BLUPs, whereas fly-resistant cows appeared in the 10th percentile. For the observational method the individuals identified as resistant varied between 8% and 20% and 8% to 12% were susceptible. For the BLUP method, the rates of susceptible and resistant cows were 12%. The agreement among methods suggests that susceptible cows can be identified by observations of fly counts, allowing for selective breeding, culling or treatment.


Resumo Para identificar vacas susceptíveis e resistentes à Haematobia irritans, moscas-dos-chifres foram contadas quinzenalmente durante três anos em 25 vacas de um rebanho Sindhi. Modelos lineares de medidas repetidas foram criados, analisando os resultados de duas formas: 1) pela contagem das moscas, considerando susceptíveis as vacas nas quais a infestação aparecia no quartil superior mais de 50% das semanas e no quartil inferior menos de 20% das semanas. Vacas resistentes foram consideradas aquelas nas quais o número de moscas apareceu no quartil inferior mais de 50% das semanas e no quartil superior menos de 20% das semanas; 2) pela melhor predição linear não-viesada (BLUP), para avaliar o efeito das vacas na contagem de moscas. As vacas foram consideradas susceptíveis quando apareciam no percentil 90 dos BLUPs e resistentes quando apareciam no percentil 10. O método observacional identificou 8% a 20% de indivíduos resistentes e 8% a 12% de susceptíveis. O método dos BLUPs identificou igual taxa de 12% de indivíduos susceptíveis e resistentes. A forte concordância entre estes dois métodos sugere que as vacas susceptíveis podem ser identificadas pela contagem das moscas, o que permite estabelecer seleção dos animais resistentes ou tratamento ou eliminação dos mais susceptíveis.

20.
Rev. bras. ortop ; 54(2): 214-218, Mar.-Apr. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1013700

RESUMO

Abstract Primary pyomyositis is a deep bacterial infection of the skeletal muscle. If left undiagnosed and untreated, the infection spreads, leading to sepsis, septic shock, and even death. The authors report a 23-year-old female presenting with piriformis pyomyositis during a treatment for Kikuchi-Fujimoto disease. Pyomyositis is a rare but potentially severe infection, which can lead to septic shock. The present case shows the need for a high degree of clinical suspicion for patients with compromised immune systems to begin treatment at an early stage. The literature demonstrates that outcomes of the treatment of piriformis pyomyositis are good.


Resumo A piomiosite primária é uma infecção bacteriana profunda do músculo esquelético. Quando não diagnosticada ou tratada, a infecção pode evoluir para sepse, choque séptico e até morte. Os autores relatam o caso de uma paciente do sexo feminino, 23 anos, apresentando piomiosite do músculo piriforme durante o tratamento da doença de Kikuchi-Fujimoto. A piomiosite é uma infecção rara, mas potencialmente grave, que pode levar ao choque séptico. Esse caso mostra a necessidade em se elevar o grau de suspeição clínica em pacientes com comprometimento do sistema imunológico, para que o tratamento seja iniciado em estágio precoce. A literatura mostra que os resultados do tratamento da piomiosite do piriforme são bons.


Assuntos
Humanos , Feminino , Adulto , Staphylococcus aureus , Linfadenite Histiocítica Necrosante , Piomiosite
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