BEHACOM - a dataset modelling users' behaviour in computers.

This paper details the methodology and approach conducted to monitor the behaviour of twelve users interacting with their computers for fifty-five consecutive days without preestablished indications or restrictions. The generated dataset, called BEHACOM, contains for each user a set of features that models, in one-minute time windows, the usage of computer resources such as CPU or memory, as well as the activities registered by applications, mouse and keyboard. It has to be stated that the collected data have been treated in a privacy-preserving way during each phase of the collection and analysis. Together with the features and their explanation, we also detail the software used to gather and process the data. Finally, this article describes the data distribution of the BEHACOM dataset.

Evaluating Quantitative Trait Locus Resistance in Tomato to Multiple Xanthomonas spp.

Bacterial spot of tomato is a foliar disease caused by four Xanthomonas species. Identifying genetic resistance in wild tomatoes and subsequent breeding of varieties has been a strategy to reduce the loss from this disease because control using pesticides has been ineffective. Three independent sources of resistance have been identified with quantitative trait loci (QTL) mapping to the centromeric region on chromosome 11. These sources are derived from Hawaii 7998 (QTL-11A), PI 114490 (QTL-11B), and LA2533 (QTL-11C). To determine which QTL introgression from chromosome 11 provides the greatest resistance to multiple species, we developed near-isogenic lines (NILs) using marker-assisted backcrossing. In parallel, we developed an NIL that contains Rx-4/Xv3, which provides major gene resistance to Xanthomonas perforans. Additionally, we combined Rx-4/Xv3 resistance with QTL-11A. These sources of resistance were independently introduced into the susceptible parent, OH88119. During a 3-year period from 2016 to 2018, we evaluated backcross-derived families and NILs from each source in independent field trials inoculated with X. perforans, X. euvesicatoria, or X. gardneri. Our results suggest that both QTL-11C and QTL-11A combined with Rx-4/Xv3 provide effective genetic resistance against multiple Xanthomonas species. In addition, we provide evidence for additive to dominant genetic action for the QTL introgressions.

Prolactinoma: tratamiento medico / Prolactinoma: medical treatment

La terapia de los llamados prolactinomas ha sido el tema de muchas controversias. La microcirugia casi nunca logra restablecer una funcion endocrinologica normal. Por el contrario, la terapia mediante sustancias agonistas de la dopamina, en este caso bromocriptina, no solo disminuye el tamano de la glandula, sino restaura la funcion hormonal. Presentamos 9 casos de los llamados micro o macroadenomas, uno de ellos con alteraciones visuales, manejados con gran exito con bromocriptina. Consideramos que este enfoque terapeutico debe ser siempre el primero en frente a un cuadro clinico y de laboratorio consistente con la presencia de hiperprolactinemia con o sin trastornos visuales