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Oral Health Prev Dent ; 17(6): 547-556, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31825027


PURPOSE: Dentin hypersensitivity (DH) is a prevalent painful condition of the teeth, the management of which lies in the obliteration of patent dentinal tubules. The purpose of this study was to compare the efficacy of 5% potassium nitrate (PN), low-level laser therapy (LLLT), and combination of low-level laser therapy and 5% potassium nitrate (LLLT+PN) in patients with fluorotic and non-fluorotic hypersensitive teeth. MATERIALS AND METHODS: Ninety self reporting patients with DH completed the randomised, double-blind study. Patients were equally divided into fluorosis group (FG), with moderate to moderately severe fluorosis and the non-fluorosis group (NFG) and subdivided into 3 groups to receive PN, LLLT (810 nm, 1 W) alone and LLLT+PN. Each participant had at least one tooth eliciting a response of ≥ 3 on a visual analog scale (VAS) to evaporative, thermal and electric tactile stimulus (digital scratch-o-meter). The teeth were evaluated at baseline, 30 min post treatment, 1 week, 4 weeks and 12 weeks. The magnitude of pressure applied by the scratch-o-meter was also assessed for all three interventions. RESULTS: Statistically, LLLT+PN was more effective in alleviating DH at all time intervals compared to baseline. However, statistically significant results (p ˂ 0.05) were seen with LLLT+PN at 12 weeks in FG. Magnitude of pressure applied showed statistically significant differences with LLLT+PN at 30 min post treatment. CONCLUSION: LLLT+PN alleviated DH at all time intervals, with a greater effect in the fluorotic group. However, LLLT+PN was more efficacious in reducing DH at 12 weeks post treatment in the fluorotic group.

Dessensibilizantes Dentinários , Sensibilidade da Dentina , Fluorose Dentária , Terapia com Luz de Baixa Intensidade , Método Duplo-Cego , Humanos , Resultado do Tratamento
J Int Acad Periodontol ; 19(3): 95-100, 2017 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-31473696


BACKGROUND: This preliminary study assesses the effects of initial periodontal treatment on salivary levels of 8-hydroxy-deoxyguanosine (8-OHdG) as a marker of oxidative stress in patients with chronic periodontitis (CP). METHODS: At baseline, clinical parameters and saliva samples were obtained from 20 patients with CP and 10 patients with clinically healthy periodontium. Saliva samples were collected, and clinical periodontal measurements were repeated at 2, 4, and 8 weeks after initial periodontal therapy in patients with CP. An enzyme-linked immunosorbent assay was used to investigate 8-OHdG levels of saliva samples. RESULTS: Statistically significant higher 8-OHdG levels of saliva and a significant decrease after initial periodontal therapy were determined in the CP group (p < 0.001). A significant positive correlation was found between 8-OHdG levels of saliva and clinical periodontal measurements (p < 0.001). CONCLUSION: Within the limits of this short-term preliminary study it can be concluded that the estimation of 8-OHdG levels in saliva may be used to evaluate the oxidative stress in periodontitis patients. It also appears that oxidative stress, which is reflected by salivary 8-OHdG levels, might reflect the present status of periodontal health.

Gen Dent ; 62(4): 72-7, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24983175


With the increasing demand for advances in diagnosis and treatment modalities, nanotechnology is being considered as a groundbreaking and viable research subject. This technology, which deals with matter in nanodimensions, has widened our views of poorly understood health issues and provided novel means of diagnosis and treatment. Researchers in the field of dentistry have explored the potential of nanoparticles in existing therapeutic modalities with moderate success. The key implementations in the field of dentistry include local drug delivery agents, restorative materials, bone graft materials, and implant surface modifications. This review provides detailed insights about current developments in the field of dentistry, and discusses potential future uses of nanotechnology.

Odontologia , Nanotecnologia , Humanos