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1.
Artigo em Inglês | MEDLINE | ID: mdl-30873290

RESUMO

Background: Periodontitis is a common oral inflammation, which is a risk factor for adverse pregnancy outcomes. Intakes of vitamin D and calcium are inversely associated with occurrence and progression of periodontitis. This study aims to assess the feasibility of a multi-component intervention, including provision of milk powder supplemented with calcium and vitamin D and periodontal therapy (PT), for improving maternal periodontal health and metabolic and inflammatory profiles of low-income Brazilian pregnant women with periodontitis. Methods: The IMPROVE trial is a feasibility randomised controlled trial (RCT) with a 2 × 2 factorial design with a parallel process evaluation. Pregnant women with periodontitis, aged 18-40 years and with < 20 gestational weeks (n = 120) were recruited and randomly allocated into four groups: (1) fortified sachet (vitamin D and calcium) and powdered milk plus PT during pregnancy, (2) placebo sachet and powdered milk plus PT during pregnancy, (3) fortified sachet (vitamin D and calcium) and powdered milk plus PT after delivery and (4) placebo sachet and powdered milk plus PT after delivery. Dentists and participants are blinded to fortification. Acceptability of study design, recruitment strategy, random allocation, data collection procedures, recruitment rate, adherence and attrition rate will be evaluated. Data on serum levels of vitamin D, calcium and inflammatory biomarkers; clinical periodontal measurements; anthropometric measurements; and socio-demographic questionnaires are collected at baseline, third trimester and 6-8 weeks postpartum. Qualitative data are collected using focus group, for analysis of favourable factors and barriers related to study adherence. Discussion: Oral health and mineral/vitamin supplementation are much overlooked in the public prenatal assistance in Brazil and of scarcity of clinical trials addressing these issues in low and middle-income countries,. To fill this gap the present study was designed to assess the feasibility of a RCT on acceptability of a multi-component intervention combining conventional periodontal treatment and consumption of milk fortified with calcium-vitamin D for improving periodontal conditions and maternal metabolic and inflammation status, among Brazilian low-income pregnant women with periodontitis. Thus, we hope that this relatively low-cost and safe multicomponent intervention can help reduce inflammation, improve maternal periodontal health and metabolic profile and consequently prevent negative gestational outcomes. Trial registration: NCT, NCT03148483. Registered on May 11, 2017.

2.
Rev. bras. odontol ; 58(3): 164-8, maio-jun. 2001.
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-296746

RESUMO

Os repositores hidroeletrolíticos foram lançados no mercado nacional com a proposta inicial de funcionarem como um repositor de líquidos e sais minerais para os praticantes de esportes. Entretanto, em razäo do seu sabor agradável e da sensasäo de "saciar a sede", estas bebidas têm se tornado muito populares, sendo consumidas indiscriminadamente por crianças e adultos. O objetivo do presente estudo foi analisar, através de uma revisäo da Literatura, o potencial erosivo que estas bebidas possam ter sobre o esmalte dentário. Para isso, foram utilizados estudos experimentais publicados na forma de artigos científicos, a partir de 1984


Assuntos
Humanos , Animais , Bovinos , Ácido Cítrico/efeitos adversos , Bebidas/efeitos adversos , Esmalte Dentário/efeitos dos fármacos , Desmineralização do Dente/induzido quimicamente , Técnicas In Vitro , Soluções para Reidratação/efeitos adversos , Erosão Dentária/induzido quimicamente , Fatores de Risco
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