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1.
BMC Public Health ; 19(1): 581, 2019 May 16.
Artigo em Inglês | MEDLINE | ID: mdl-31096940

RESUMO

BACKGROUND: The inadequate management of solid waste impacts populations' health and quality of life, and disproportionately affects developing countries. This study aims to describe a protocol for epidemiological diagnosis, the purpose being to estimate the prevalence of chronic and communicable and non communicable diseases in waste pickers, and the occupational and environmental risk factors to which these are exposed. METHODS: This is a cross-sectional study, based on survey design in an area of extreme social vulnerability - the largest garbage dump in Latin America. Using a multidimensional research protocol, divided in three stages: 1- The identification of the subjects, and the scheduling of tests; 2- Situational diagnosis through interviews, anthropometric evaluation, measuring blood pressure, collecting hair and nail samples to detect exposure to heavy metals and undertaking laboratory tests; 3- The return of the waste pickers to receive the test results, followed by referral to the health team and to report occupational accidents. RESULTS: One thousand twenty-five waste pickers undertook tests and interviews. The majority were women (67.0%), with 36-45 years old (45.7%), and 96.0% had children. In total, 27.3% of the participants did not attend to any school and 47.7% were educated only up to primary level. The majority of waste pickers (68.70%) reported accidents and most of them (89.69%) were related to sharp objects. The mean time working in this open dump was 15 years. According the anthropometric measure, 32.6% were overweight and 21.1% were obese. The most common reported diseases were: osteomuscular disorders (78.7%); arboviruses (28.6%); episodic diarrhea (24.9%); hypertension (24.2%); bronchitis (14.3%); intestinal worms (12.6%) and diabetes (10.1%). According to the blood tests, the values outside the reference limits were: Uric acid (23.89%); creatinine (54.06%); GGT range (16.04%); SGOT - Serum Glutamic Oxaloacetic Transaminase (5.29%); SGPT - serum Glutamic-Pyruvic Transaminase (35.52%). CONCLUSIONS: This study is the first to evaluate multiple risks and diseases in the majority of waste pickers working in the largest garbage dump of a continent. These findings highlight the importance to address urgently the environmental, social and health impacts related to the management of solid waste in developmental countries to protect these workers and their families.


Assuntos
Acidentes de Trabalho/estatística & dados numéricos , Resíduos de Alimentos , Doenças Profissionais/epidemiologia , Resíduos Sólidos , Adulto , Pré-Escolar , Estudos Transversais , Países em Desenvolvimento , Projetos de Pesquisa Epidemiológica , Feminino , Humanos , América Latina/epidemiologia , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/etiologia , Qualidade de Vida , Medição de Risco
2.
Texto & contexto enferm ; 28: e20170279, 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1004807

RESUMO

ABSTRACT Objective: to describe some methodological considerations on the Systematic Review of Mixed Methods developed by the Joanna Briggs Institute, seeking to disseminate the use of this methodology, exemplifying its use and demonstrating the benefits for nursing research. Method: it is an article of reflection. Result: it can be seen that the Systematic Review of Mixed Methods demonstrates that it is a research method that aligns with the characteristics of nursing care, making it possible to make a broader analysis of the different aspects of care such as: the viability of an activity or intervention, its adequacy to a specific context, the significance of the intervention for the patient and their effectiveness. Conclusion: the possibility of incorporating scientific evidence into the clinical practice by the decision making, increasing the focus of care and bringing benefits to the patients as well as the public policies is envisaged. This method values the context of care, cost-effectiveness and the preferences of patients, caregivers and health care providers.


RESUMEN Objetivo: describir algunas consideraciones metodológicas sobre la Revisión Sistemática de Métodos Mixtos desarrollada por el Instituto Joanna Briggs, buscando divulgar el uso de esta metodología, ejemplificando su utilización y demostrando los beneficios para la investigación en enfermería. Método: se trata de un artículo de reflexión. Resultados: se observa que la Revisión Sistemática de Métodos Mixtos demuestra ser un método de investigación que se alinea a las características del cuidado en enfermería, posibilitando hacer un análisis más amplio de los diferentes aspectos del cuidado como: la viabilidad de una evaluación actividad o intervención, su adecuación a un determinado contexto, la significancia de la intervención para el paciente y su eficacia. Conclusión: se vislumbra la posibilidad de incorporar evidencias científicas a la práctica clínica por la toma de decisión, ampliando el foco de cuidado y aportando beneficios a los pacientes y a las políticas públicas. Este método valora el contexto de la atención, la relación costo-eficacia, así como las preferencias de los pacientes, cuidadores y proveedores de atención de salud.


RESUMO Objetivo: descrever algumas considerações metodológicas sobre a Revisão Sistemática de Métodos Mistos desenvolvida pelo Instituto Joanna Briggs, buscando divulgar o uso desta metodologia, exemplificando sua utilização e demonstrando os benefícios para a pesquisa em enfermagem. Método: trata-se de um artigo de reflexão. Resultado: percebe-se que a Revisão Sistemática de Métodos Mistos demonstra ser um método de pesquisa que se alinha às características do cuidado em enfermagem, possibilitando fazer uma análise mais ampla dos diferentes aspectos do cuidado como: a viabilidade de uma atividade ou intervenção, sua adequação a um determinado contexto, a significância da intervenção para o paciente e a sua eficácia. Conclusão: vislumbra-se a possibilidade de incorporar evidências científicas à prática clínica pela tomada de decisão, ampliando o foco de cuidado e trazendo benefícios aos pacientes bem como às políticas públicas. Este método valoriza o contexto da prestação de cuidados, a relação custo-eficácia e as preferências dos pacientes, cuidadores e provedores de cuidados de saúde.

3.
Codas ; 30(5): e20170225, 2018 Oct 22.
Artigo em Português, Inglês | MEDLINE | ID: mdl-30365649

RESUMO

PURPOSE: Characterize voices of adult individuals without vocal complaints and verify the effect of gender and age with the use of acoustic measures. METHODS: One-hundred and seventy-six voice recordings belonging to adults between 19 and 59 years old, divided into four age groups, for decade, recorded in a database were analyzed. All voices analyzed were classified with no deviation in vocal quality. Acoustic analysis of the parameters was performed: Fundamental Frequency (sustained vowel and connected speech), Jitter, Shimmer and Noise-to-Harmonic Ratio through Multi Dimension Voice Program (KayPentax) software. The effect of gender, age and possible interactions were verified through the Factorial Anova test. When necessary, post hoc was performed with the Least Significant Difference test. RESULTS: There were changes in the voice as a function of age, with a decrease in the Fundamental Frequency in the vowel and connected speech modalities in women and in the Fundamental Frequency of the speech in men. In men, an increase in shimmer measure was observed with the advancing age. Differences between genders were found in the measures of Fundamental Frequency, Jitter and Noise to Harmonic Ratio. CONCLUSION: Vocal changes due to advancing age can be identified acoustically at the end of adulthood, and in women, these changes can be marked previously to the menopausal period.

4.
Folia Phoniatr Logop ; 70(2): 82-89, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30041244

RESUMO

OBJECTIVES: This study establishes normative nasalance values for middle-aged and elderly Brazilian Portuguese-speakers and investigates age and gender effects across the life span. METHODS: Nasalance scores were obtained from 62 middle-aged (45-59 years) and 60 elderly (60-79 years) participants with normal speech for 3 nonnasal, 1 phonetically balanced, and 2 nasal-loaded test sentences using the Nasometer II 6400. The data were combined with a published data set of 237 speakers in 4 groups: children (5-9 years), adolescents (10-19 years), young adults (20-24 years), and mature adults (25-35 years). A repeated-measures analysis of variance was used to investigate differences between the stimuli by gender and age groups. RESULTS: There were statistically significant effects of stimulus, gender, and age group, as well as a stimulus-age group interaction effect and a gender-age group interaction effect. The females' mean nasalance scores were higher than those of the males. The mean nasalance scores for the child, adolescent, and young and mature adult speakers were significantly lower than those for the elderly speakers, and the children's scores were significantly lower than those of the middle-aged speakers. CONCLUSION: Higher nasalance scores among middle-aged and elderly speakers may indicate physiological changes affecting oral-nasal balance in speech across the life span.

5.
BMC Nephrol ; 19(1): 179, 2018 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-30005635

RESUMO

BACKGROUND: Angiotensin II (Ang II) contributes to the progression of renal diseases associated with proteinuria and glomerulosclerosis mainly by inducing podocyte apoptosis. In the present study, we investigated whether the chronic effects of Ang II via AT1 receptor (AT1R) would result in endoplasmic reticulum (ER) stress/PKC-delta/p38 MAPK stimulation, and consequently podocyte apoptosis. METHODS: Wistar rats were treated with Ang II (200 ng·kg-1·min-1, 42 days) and or losartan (10 mg·kg-1·day-1, 14 days). Immortalized mouse podocyte were treated with 1 µM Ang II and/or losartan (1 µM) or SB203580 (0.1 µM) (AT1 receptor antagonist and p38 MAPK inhibitor) for 24 h. Kidney sections and cultured podocytes were used to evaluate protein expression by immunofluorescence and immunoblotting. Apoptosis was evaluated by flow cytometry and intracellular pH (pHi) was analyzed using microscopy combined with the fluorescent probe BCECF/AM. RESULTS: Compared with controls, Ang II via AT1R increased chaperone GRP 78/Bip protein expression in rat glomeruli (p < 0.001) as well as in podocyte culture (p < 0.01); increased phosphorylated eIf2-α (p < 0.05), PKC-delta (p < 0.01) and p38 MAPK (p < 0.001) protein expression. Furthermore, Ang II induced p38 MAPK-mediated late apoptosis and increased the Bax/Bcl-2 ratio (p < 0.001). Simultaneously, Ang II via AT1R induced p38 MAPK-NHE1-mediated increase of pHi recovery rate after acid loading. CONCLUSION: Together, our results indicate that Ang II-induced podocyte apoptosis is associated with AT1R/ER stress/PKC-delta/p38 MAPK axis and enhanced NHE1-mediated pHi recovery rate.

6.
Rev. pesqui. cuid. fundam. (Online) ; 10(3): 856-862, jul.-set. 2018.
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-906762

RESUMO

Objective: The study's goal has been to analyze how the pregnant woman perceives the partner's involvement in the prenatal routine. Methods: It is a descriptive-exploratory study with a qualitative approach. Data collection was performed from March to June 2016, through a semi-structured interview. The research participants were 11 pregnant women, starting at the 28th week of gestation, who were submitted to content analysis in the thematic modality. Results: Data analysis shows that only one participant had complete follow-up by the partner, another five reported the partner's presence only during the obstetrical ultrasonography procedure. Regarding the women that reported partner's absence, the work was highlighted as the main factor; it was also observed that gender issues influence this absence, since the pregnancy is seen as a woman exclusive moment. Conclusion: It is essential that health services can become sensitive to the insertion of the partner in this routine. Furthermore, an intersectoral partnership between the health, the legal and the educational sectors must become a reality in order to stimulate this change


Objetivo: Analisar como a gestante percebe a participação do parceiro na rotina pré-natal. Método: Estudo descritivo exploratório de abordagem qualitativa. Coleta de dados entre março e junho de 2016, por meio de entrevista semiestruturada, com 11 gestantes, a partir da 28ª semana de gestação, sendo estes submetidos à análise de conteúdo na modalidade temática. Resultados: Das participantes do estudo, apenas uma teve acompanhamento integral do parceiro, outras cinco relataram a presença apenas na realização da ultrassonografia obstétrica. Daquelas que relataram ausência, o trabalho foi apontado como principal fator, também se observou que questões de gênero influenciam nesta ausência, pois a gestação é vista como momento exclusivo da mulher. Conclusão: É imprescindível que os serviços de saúde estejam sensíveis à inserção do parceiro nesta rotina, e que haja parcerias intersetoriais entre a saúde, o setor jurídico e a educação que possam estimular esta mudança


Objetivo: Analizar cómo la madre percibe la participación del socio en la rutina prenatal. Método: Estudio exploratorio descriptivo de enfoque cualitativo. Recolección se llevó a cabo entre marzo y junio el año 2016, através de entrevistas semiestructuradas con 11 mujeres embarazadas desde la semana 28 de embarazo, que están sometidas a análisis de contenido en la modalidad temática. Resultados: De las participantes en el estudio, sólo uno tenía pareja de supervisión, otras cinco personas informaron de la presencia sólo en la realización de ultrasonido obstétrico. De los que reportaron ausencia, el trabajo fue considerado como el principal factor, también observaron que las cuestiones de género influyen en esta ausencia porque el embarazo es visto como un momento único de la mujer. Conclusión: Es esencial que los servicios de salud son sensibles a la inclusión del socio en esta rutina, y que tienen alianzas intersectoriales entre la salud, el sector jurídico y la educación que pueden estimular este cambio


Assuntos
Humanos , Masculino , Feminino , Gravidez , Adulto , Gestantes , Cuidado Pré-Natal , Cônjuges , Paternidade , Saúde da Mulher
7.
Nat Protoc ; 13(4): 681-704, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29543796

RESUMO

Poly(vinylidene fluoride) (PVDF) and its copolymers are the polymers with the highest dielectric constants and electroactive responses, including piezoelectric, pyroelectric and ferroelectric effects. This semicrystalline polymer can crystallize in five different forms, each related to a different chain conformation. Of these different phases, the ß phase is the one with the highest dipolar moment and the highest piezoelectric response; therefore, it is the most interesting for a diverse range of applications. Thus, a variety of processing methods have been developed to induce the formation of the polymer ß phase. In addition, PVDF has the advantage of being easily processable, flexible and low-cost. In this protocol, we present a number of reproducible and effective methods to produce ß-PVDF-based morphologies/structures in the form of dense films, porous films, 3D scaffolds, patterned structures, fibers and spheres. These structures can be fabricated by different processing techniques, including doctor blade, spin coating, printing technologies, non-solvent-induced phase separation (NIPS), temperature-induced phase separation (TIPS), solvent-casting particulate leaching, solvent-casting using a 3D nylon template, freeze extraction with a 3D poly(vinyl alcohol) (PVA) template, replica molding, and electrospinning or electrospray, with the fabrication method depending on the desired characteristics of the structure. The developed electroactive structures have shown potential to be used in a wide range of applications, including the formation of sensors and actuators, in biomedicine, for energy generation and storage, and as filtration membranes.

8.
Adv Healthc Mater ; 7(5)2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29280314

RESUMO

Magnetic nanoparticles (NPs) are emerging as an important class of biomedical functional nanomaterials in areas such as hyperthermia, drug release, tissue engineering, theranostic, and lab-on-a-chip, due to their exclusive chemical and physical properties. Although some works can be found reviewing the main application of magnetic NPs in the area of biomedical engineering, recent and intense progress on magnetic nanoparticle research, from synthesis to surface functionalization strategies, demands for a work that includes, summarizes, and debates current directions and ongoing advancements in this research field. Thus, the present work addresses the structure, synthesis, properties, and the incorporation of magnetic NPs in nanocomposites, highlighting the most relevant effects of the synthesis on the magnetic and structural properties of the magnetic NPs and how these effects limit their utilization in the biomedical area. Furthermore, this review next focuses on the application of magnetic NPs on the biomedical field. Finally, a discussion of the main challenges and an outlook of the future developments in the use of magnetic NPs for advanced biomedical applications are critically provided.

9.
CoDAS ; 30(5): e20170225, 2018. tab
Artigo em Português | LILACS-Express | ID: biblio-984220

RESUMO

RESUMO Objetivo Caracterizar as vozes de indivíduos adultos sem queixas vocais e verificar o efeito de gênero e idade a partir de um conjunto de medidas acústicas. Método Foram analisadas 176 gravações de vozes pertencentes a adultos com idades entre 19 e 59 anos, divididas em quatro grupos etários, por década, armazenadas em uma base de dados. Todas as vozes analisadas foram classificadas com ausência de desvio na qualidade vocal. Realizou-se análise acústica dos parâmetros: Frequência Fundamental (vogal sustentada e fala encadeada), Jitter , Shimmer e Noise-to-Harmonic Ratio por meio software Multi Dimension Voice Program (KayPentax). O efeito de gênero, idade e possíveis interações foram verificados por meio do teste Anova Fatorial. Quando necessário, realizou-se post hoc com o teste Least Significant Difference. Resultados Houve mudanças na voz em função da idade, com diminuição da Frequência Fundamental nas modalidades vogal e fala encadeada em mulheres e na Frequência Fundamental da fala em homens. Em homens, foi observado aumento da medida de shimmer com o avanço da idade. Foram verificadas diferenças entre os gêneros nas medidas de Frequência Fundamental, Jitte r e Noise to Harmonic Ratio. Conclusão Mudanças vocais decorrentes do avanço da idade podem ser identificadas acusticamente, no final da fase adulta e, em mulheres, essas mudanças podem ser marcadas previamente ao período da menopausa.


ABSTRACT Purpose Characterize voices of adult individuals without vocal complaints and verify the effect of gender and age with the use of acoustic measures. Methods One-hundred and seventy-six voice recordings belonging to adults between 19 and 59 years old, divided into four age groups, for decade, recorded in a database were analyzed. All voices analyzed were classified with no deviation in vocal quality. Acoustic analysis of the parameters was performed: Fundamental Frequency (sustained vowel and connected speech), Jitter, Shimmer and Noise-to-Harmonic Ratio through Multi Dimension Voice Program (KayPentax) software. The effect of gender, age and possible interactions were verified through the Factorial Anova test. When necessary, post hoc was performed with the Least Significant Difference test. Results There were changes in the voice as a function of age, with a decrease in the Fundamental Frequency in the vowel and connected speech modalities in women and in the Fundamental Frequency of the speech in men. In men, an increase in shimmer measure was observed with the advancing age. Differences between genders were found in the measures of Fundamental Frequency, Jitter and Noise to Harmonic Ratio. Conclusion Vocal changes due to advancing age can be identified acoustically at the end of adulthood, and in women, these changes can be marked previously to the menopausal period.

10.
Kidney Blood Press Res ; 42(6): 1277-1289, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29262407

RESUMO

BACKGROUND/AIMS: To assess the possible contribution of the ß-adrenergic overstimulation in early stages of renal injury, the present study evaluated, in rats, the effects of the ß-adrenoceptor agonist isoproterenol (ISO) on renal function and morphology, as well as the renal mRNA and protein expression of the NADPH oxidase isoform 4 (Nox 4) and subunit p22phox, endoplasmic reticulum (ER) stress, pro-inflammatory, pro-apoptotic and renin-angiotensin system (RAS) components. METHODS: Wistar rats received ISO (0.3 mg.kg-1.day-1 s.c.) or vehicle (control) for eight days. At the end of the treatment, food and water intake, urine output and body weight gain were evaluated and renal function studies were performed. Renal tissue was used for the morphological, quantitative PCR and immunohistochemical studies. RESULTS: ISO did not change metabolic parameters or urine output. However it induced a decrease in renal blood flow and an increase in the filtration fraction. These changes were accompanied by increased cortical mRNA and protein expression for the renal oxidative stress components including Nox 4 and p22phox; ER stress, pro-inflamatory, pro-apoptotic as well as RAS components. ISO also induced a significant increase in medullar renin protein expression. CONCLUSION: These findings support relevant information regarding the contribution of specific ß-adrenergic hyperactivity in early stage of renal injury, indicating the reactive oxygen species, ER stress and intrarenal RAS as important factors in this process.


Assuntos
Agonistas Adrenérgicos beta/farmacologia , Rim/lesões , Animais , Estresse do Retículo Endoplasmático , Isoproterenol/farmacologia , Testes de Função Renal , Ratos , Ratos Wistar , Espécies Reativas de Oxigênio , Sistema Renina-Angiotensina
11.
Codas ; 29(3): e20150311, 2017 Jun 08.
Artigo em Português, Inglês | MEDLINE | ID: mdl-28614457

RESUMO

Purpose: To investigate vocal quality variability after applying tongue trills associated with transcutaneous electrical nerve stimulation (TENS) on the larynx of women with normal laryngeal function. Additionally, to verify the effect of this technique over time on voice quality. Methods: Participants were 40 women (average 23.4 years) without vocal complaints. The procedure involved tongue trills with or without TENS for 3 minutes, rest and repeating the technique for another 2 minutes. The participants' voices were recorded before (Pre), after three minutes (Post 3min) and after two additional minutes (Post 5min) applying the technique. TENS with two electrodes was used on the thyroid cartilage. Self-assessment, acoustic and perceptual analysis were performed. Results: When comparing tongue trills in isolation and associated with TENS, a greater sense of stability in phonation (self-assessment) and improvement in voice quality (perceptual evaluation) was observed in the combination technique. There was no statistical difference in acoustics findings between tongue trills in isolation and associated with TENS. When comparing the time effect of tongue trills with TENS in self-assessment there was a perception of less muscle tension (3min) and greater comfort during phonation (5 min); in the acoustic analysis, there was an increase of F0 (3 and 5 min) and intensity (5 min) when compared to Pre-moment; in the perceptual evaluation, better voice quality (3min). Conclusion: Comparing tongue trills in isolation and associated with TENS, there were changes in the comfort and muscle tension perception, as well as in vocal quality. On the other hand, tongue trills associated with TENS performed in 3 or 5 minutes resulted in beneficial effects on the voice identified in the assessments.


Assuntos
Língua/fisiologia , Estimulação Elétrica Nervosa Transcutânea , Treinamento da Voz , Voz/fisiologia , Adolescente , Adulto , Feminino , Humanos , Fonação/fisiologia , Medida da Produção da Fala , Fatores de Tempo , Qualidade da Voz , Adulto Jovem
12.
Colloids Surf B Biointerfaces ; 157: 48-55, 2017 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-28575740

RESUMO

Zinc-decorated magnetic silica spheres were developed, optimized and tested for the capture and separation of l-histidine. The magnetic silica spheres were prepared using a simple sol-gel method and show excellent magnetic characteristics, adsorption capacity toward metal ions, and stability in aqueous solution in a wide pH range. The binding capacity of zinc-decorated magnetic silica spheres to histidine proved to be strongly influenced by the morphology, composition and concentration of metal at the surface of the magnetic silica spheres and therefore these parameters should be carefully controlled in order to maximize the performance for protein purification purposes. Optimized zinc-decorated magnetic silica spheres demonstrate a binding capacity to l-histidine of approximately 44mgg-1 at the optimum binding pH buffer.


Assuntos
Magnetismo , Proteínas/química , Dióxido de Silício/química , Zinco/química , Adsorção , Biotecnologia , Histidina/química , Concentração de Íons de Hidrogênio
13.
Rev. pesqui. cuid. fundam. (Online) ; 9(2): 340-346, abr.-jun. 2017.
Artigo em Inglês, Português | LILACS | ID: biblio-836348

RESUMO

Objective: To analyze the perception of adolescents about the life activity “express sexuality”. Method: This is an action-research developed at a school in the periphery of Fortaleza, Ceará, Brazil. We selected 25 adolescents to participate in an educational workshop on sexuality. Results: We observed vulnerability of adolescents to early pregnancy and STDs. Despite having prior knowledge about safe sex practices, we verified they expose themselves to risky situations. Conclusion: We concluded that the inclusion of school activities that promote not only the acquisition of knowledge, but, above all, activities of reflection in search of awareness of body protection, prevention of unwanted pregnancy and STDs is needed.


Objetivo: Analisar a percepção de adolescentes acerca da atividade de vida “exprimir sexualidade”. Método: Trata-se de pesquisa-ação desenvolvida em uma escola localizada na periferia de Fortaleza, Ceará. Foram selecionados 25 adolescentes para participarem de uma oficina educativa sobre sexualidade. Resultados: Observou-se vulnerabilidade dos adolescentes para gravidez precoce e DSTs. Verificou-se que, apesar de possuírem conhecimento prévio sobre práticas sexuais seguras, expõem-se a situações de risco. Conclusões: Conclui-se que há necessidade de inserção de atividades na escola que promovam não apenas aquisição de conhecimento, mas, sobretudo atividades de reflexão em buscada conscientização sobre proteção do corpo, prevenção de gravidez indesejada e DSTs.


Objetivo: Analizar la percepción de adolescentes acerca de la actividad de vida “expresar la sexualidad”. Método: Investigación-acción desarrollada en escuela de Fortaleza, Ceará, Brasil. Fueron elegidos 25 adolescentes para participar de taller educativo sobre sexualidad. Resultados: Fue observada vulnerabilidad de adolescentes a embarazos precoces y enfermedades de transmisión sexual. A pesar de tener conocimiento previo acerca de las prácticas de sexo seguro, los adolescentes se exponen a situaciones de riesgo. Conclusiones: Hay necesidad de inclusión de actividades escolares que promueven no sólo la adquisición de conocimientos, pero actividades de reflexión en busca de la conciencia acerca de la protección del cuerpo y la prevención de embarazos no deseados y ETS.


Assuntos
Humanos , Adolescente , Educação em Saúde , Promoção da Saúde , Desenvolvimento Psicossexual , Serviços de Saúde Escolar , Sexualidade/psicologia , Brasil , Comportamentos Relacionados com a Saúde
14.
Rev. pesqui. cuid. fundam. (Online) ; 9(2): 340-346, abr.-jun. 2017.
Artigo em Inglês, Português | BDENF - Enfermagem | ID: bde-30362

RESUMO

Objective: To analyze the perception of adolescents about the life activity “express sexuality”. Method: This is an action-research developed at a school in the periphery of Fortaleza, Ceará, Brazil. We selected 25 adolescents to participate in an educational workshop on sexuality. Results: We observed vulnerability of adolescents to early pregnancy and STDs. Despite having prior knowledge about safe sex practices, we verified they expose themselves to risky situations. Conclusion: We concluded that the inclusion of school activities that promote not only the acquisition of knowledge, but, above all, activities of reflection in search of awareness of body protection, prevention of unwanted pregnancy and STDs is needed.(AU)


Objetivo: Analisar a percepção de adolescentes acerca da atividade de vida “exprimir sexualidade”. Método: Trata-se de pesquisa-ação desenvolvida em uma escola localizada na periferia de Fortaleza, Ceará. Foram selecionados 25 adolescentes para participarem de uma oficina educativa sobre sexualidade. Resultados: Observou-se vulnerabilidade dos adolescentes para gravidez precoce e DSTs. Verificou-se que, apesar de possuírem conhecimento prévio sobre práticas sexuais seguras, expõem-se a situações de risco. Conclusões: Conclui-se que há necessidade de inserção de atividades na escola que promovam não apenas aquisição de conhecimento, mas, sobretudo atividades de reflexão em buscada conscientização sobre proteção do corpo, prevenção de gravidez indesejada e DSTs.(AU)


Objetivo: Analizar la percepción de adolescentes acerca de la actividad de vida “expresar la sexualidad”. Método: Investigación-acción desarrollada en escuela de Fortaleza, Ceará, Brasil. Fueron elegidos 25 adolescentes para participar de taller educativo sobre sexualidad. Resultados: Fue observada vulnerabilidad de adolescentes a embarazos precoces y enfermedades de transmisión sexual. A pesar de tener conocimiento previo acerca de las prácticas de sexo seguro, los adolescentes se exponen a situaciones de riesgo. Conclusiones: Hay necesidad de inclusión de actividades escolares que promueven no sólo la adquisición de conocimientos, pero actividades de reflexión en busca de la conciencia acerca de la protección del cuerpo y la prevención de embarazos no deseados y ETS.(AU)


Assuntos
Humanos , Adolescente , Sexualidade/psicologia , Desenvolvimento Psicossexual , Educação em Saúde , Promoção da Saúde , Estilo de Vida Saudável , Brasil
15.
CoDAS ; 29(3): e20150311, 2017. tab
Artigo em Português | LILACS-Express | ID: biblio-840133

RESUMO

RESUMO Objetivo Verificar variação da qualidade vocal após realização da técnica de vibração sonorizada de língua associada à estimulação nervosa elétrica transcutânea (TVSL+TENS) sobre a laringe em mulheres com função laríngea normal. Verificar, ainda, a influência do tempo de realização desta técnica na voz. Método Participaram 40 mulheres (média 23,4 anos) sem queixas ou alterações vocais. Foi realizada TVSL associada ou não à TENS por 3 minutos, descanso e realização da técnica por mais 2 minutos (total 5 min). Foram feitas gravações das vozes antes (Pré), após três minutos (Pós 3 min) e após dois minutos adicionais de técnica (Pós 5 min). Utilizou-se a corrente TENS, com dois eletrodos sobre a cartilagem tireóidea. Realizou-se autoavaliação, avaliação acústica e perceptivoauditiva. Resultados Ao comparar TVSL isolada e TVSL+TENS observou-se que a combinação das técnicas resultou em sensação de maior estabilidade na emissão vocal (autoavaliação) e melhor ganho na qualidade vocal (avaliação perceptivoauditiva). Não houve diferença estatística nos achados acústicos entre TVSL e TVSL+TENS. Ao considerar a TVSL+TENS e comparar seu tempo de realização, observou-se, na autoavaliação, sensação de menor tensão muscular (3 min) e maior conforto da emissão (5 min); na análise acústica, elevação de F0 (3 e 5 min) e intensidade (5 min), em relação ao momento Pré; e na avaliação perceptivoauditiva, melhor qualidade vocal (3 min). Conclusão Comparando TVSL isolada e TVSL+TENS, houve mudanças na sensação de conforto e tensão muscular e também, na qualidade vocal. Por outro lado, a TVSL+TENS realizada em 3 ou 5 mintuos resultou em efeitos benéficos na voz, identificados nas avaliações realizadas.


ABSTRACT Purpose To investigate vocal quality variability after applying tongue trills associated with transcutaneous electrical nerve stimulation (TENS) on the larynx of women with normal laryngeal function. Additionally, to verify the effect of this technique over time on voice quality. Methods Participants were 40 women (average 23.4 years) without vocal complaints. The procedure involved tongue trills with or without TENS for 3 minutes, rest and repeating the technique for another 2 minutes. The participants’ voices were recorded before (Pre), after three minutes (Post 3min) and after two additional minutes (Post 5min) applying the technique. TENS with two electrodes was used on the thyroid cartilage. Self-assessment, acoustic and perceptual analysis were performed. Results When comparing tongue trills in isolation and associated with TENS, a greater sense of stability in phonation (self-assessment) and improvement in voice quality (perceptual evaluation) was observed in the combination technique. There was no statistical difference in acoustics findings between tongue trills in isolation and associated with TENS. When comparing the time effect of tongue trills with TENS in self-assessment there was a perception of less muscle tension (3min) and greater comfort during phonation (5 min); in the acoustic analysis, there was an increase of F0 (3 and 5 min) and intensity (5 min) when compared to Pre-moment; in the perceptual evaluation, better voice quality (3min). Conclusion Comparing tongue trills in isolation and associated with TENS, there were changes in the comfort and muscle tension perception, as well as in vocal quality. On the other hand, tongue trills associated with TENS performed in 3 or 5 minutes resulted in beneficial effects on the voice identified in the assessments.

16.
Codas ; 0: 0, 2016 Jul 04.
Artigo em Inglês, Português | MEDLINE | ID: mdl-27383228

RESUMO

PURPOSE: This study aimed to determine nasalance values for syllables produced by Brazilian Portuguese speakers of different ages and gender. METHODS: Nasalance scores were collected for 14 syllables (10 orals and 4 nasals) using Nasometer II 6400. The participants were 245 Brazilian Portuguese speakers (121 males and 124 females), both genders, divided into four age groups: 57 children, 61 adolescents, 65 young adults and 62 adults. RESULTS: Nasalance scores for nasal syllables were higher than for oral syllables. For both, oral and nasal syllables, nasalance scores were higher for vowel /i/ than for /a/. Across all syllables, the females' nasalance scores were higher than males, with most of this difference attributed to the oldest age group where females mean nasalance was three points higher than males. CONCLUSION: Values obtained demonstrated nasalance scores variation according to gender, particularly for the adult group and for the syllables tested.


Assuntos
Acústica da Fala , Medida da Produção da Fala , Fala/fisiologia , Adolescente , Adulto , Fatores Etários , Brasil , Criança , Feminino , Humanos , Masculino , Nariz , Valores de Referência , Fatores Sexuais , Adulto Jovem
17.
CoDAS ; 28(3): 278-283, tab
Artigo em Português | LILACS-Express | ID: lil-788079

RESUMO

RESUMO Objetivo o objetivo do estudo foi estabelecer valores de nasalância para sílabas produzidas por falantes do Português Brasileiro com diferentes idades e sexo. Métodos Participaram deste estudo 245 falantes do Português Brasileiro (121 do sexo masculino e 124 do sexo feminino), de ambos os sexos, divididos em quatro grupos de idade: 57 crianças, 61 adolescentes, 65 adultos jovens e 62 adultos. Valores de nasalância foram obtidos para um conjunto de 14 sílabas (dez orais e quatro nasais), utilizando o Nasômetro II 6400. Resultados Valores de nasalância mais altos foram encontrados para sílabas nasais quando comparadas às orais e para as sílabas constituídas pela vogal /i/ quando comparadas com a vogal /a/. Valores de nasalância mais altos foram obtidos para mulheres quando comparados aos dos homens e, particularmente, para os adultos. Conclusão Valores de nasalância das sílabas produzidas por falantes do Português Brasileiro demonstraram variação quanto às sílabas investigadas e também para variável sexo para falantes adultos.


ABSTRACT Purpose This study aimed to determine nasalance values for syllables produced by Brazilian Portuguese speakers of different ages and gender. Methods Nasalance scores were collected for 14 syllables (10 orals and 4 nasals) using Nasometer II 6400. The participants were 245 Brazilian Portuguese speakers (121 males and 124 females), both genders, divided into four age groups: 57 children, 61 adolescents, 65 young adults and 62 adults. Results Nasalance scores for nasal syllables were higher than for oral syllables. For both, oral and nasal syllables, nasalance scores were higher for vowel /i/ than for /a/. Across all syllables, the females’ nasalance scores were higher than males, with most of this difference attributed to the oldest age group where females mean nasalance was three points higher than males. Conclusion Values obtained demonstrated nasalance scores variation according to gender, particularly for the adult group and for the syllables tested.

18.
Int J Infect Dis ; 33: 205-8, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25722282

RESUMO

OBJECTIVES: The purpose of this study was to compare methods for assessing compliance with hand hygiene in an intensive care unit (ICU), a step-down unit (SDU), and a hematology-oncology unit. METHODS: Over a 20-week period, we compared hand hygiene compliance measurements by three different methods: direct observation, electronic handwash counter for alcohol gel, and measuring the volume of product used (alcohol gel) in an ICU, an SDU, and a hematology-oncology unit of a tertiary care, private hospital. RESULTS: By direct observation we evaluated 1078 opportunities in the ICU, 1075 in the SDU, and 517 in the hematology-oncology unit, with compliance rates of 70.7%, 75.4%, and 73.3%, respectively. A total of 342,299, 235,914, and 248,698 hand hygiene episodes were recorded by the electronic devices in the ICU, SDU, and hematology-oncology unit, respectively. There were also 127.2 ml, 85.3 ml, and 67.6 ml of alcohol gel used per patient-day in these units. We could find no correlation between the three methods. CONCLUSIONS: Hand hygiene compliance was reasonably high in these units, as measured by direct observation. However, a lack of correlation with results obtained by other methodologies brings into question the validity of direct observation results, and suggests that periodic audits using other methods may be needed.


Assuntos
Fidelidade a Diretrizes , Higiene das Mãos/normas , Higiene das Mãos/estatística & dados numéricos , Hematologia , Humanos , Unidades de Terapia Intensiva , Oncologia , Garantia da Qualidade dos Cuidados de Saúde/métodos , Atenção Terciária à Saúde
19.
Folia Phoniatr Logop ; 67(5): 238-44, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26844554

RESUMO

OBJECTIVE: Normative data were established for newly developed speech materials for nasalance assessment in Brazilian Portuguese. MATERIALS AND METHODS: Nasalance scores of preexisting passages (oral ZOO-BR, low-pressure oral ZOO-BR2 and NASAL-BR), new nasalance passages (oral Dudu no zoológico, oral Dudu no bosque, oral-nasal O cãozinho Totó and nasal O nenê) and Brasilcleft articulation screening sentences were collected from 245 speakers of Brazilian Portuguese, including 121 males and 124 females, divided into 4 groups: children (5-9 years), adolescents (10-19 years), young adults (20-24 years) and adults (25-35 years). RESULTS: Across all nasalance passages, adult females scored on average 2 percentage points higher than males. Children scored 2-4 percentage points lower than older groups for the preexisting nasalance passages ZOO-BR and ZOO-BR2. Nasalance scores for the new nasalance passages were not significantly different from the preexisting passages. Scores for high-pressure sentences did not differ significantly from the oral nasalance passage Dudu no bosque. CONCLUSION: The nasalance scores for the new nasalance passages were equivalent to the preexisting materials. The new shortened and simplified nasalance passages will be useful for assessing young children. Normative scores for the Brasilcleft high-pressure sentences were equivalent to the new oral passage Dudu no bosque.


Assuntos
Transtornos da Articulação/diagnóstico , Fissura Palatina/diagnóstico , Linguagem , Fonética , Espectrografia do Som , Acústica da Fala , Distúrbios da Fala/diagnóstico , Medida da Produção da Fala , Adolescente , Adulto , Fatores Etários , Transtornos da Articulação/classificação , Brasil , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Valores de Referência , Fatores Sexuais , Distúrbios da Fala/classificação , Adulto Jovem
20.
World J Biol Chem ; 5(2): 141-60, 2014 May 26.
Artigo em Inglês | MEDLINE | ID: mdl-24921005

RESUMO

Aside from Polo and Aurora, a third but less studied kinase family involved in mitosis regulation is the never in mitosis-gene A (NIMA)-related kinases (Neks). The founding member of this family is the sole member NIMA of Aspergillus nidulans, which is crucial for the initiation of mitosis in that organism. All 11 human Neks have been functionally assigned to one of the three core functions established for this family in mammals: (1) centrioles/mitosis; (2) primary ciliary function/ciliopathies; and (3) DNA damage response (DDR). Recent findings, especially on Nek 1 and 8, showed however, that several Neks participate in parallel in at least two of these contexts: primary ciliary function and DDR. In the core section of this in-depth review, we report the current detailed functional knowledge on each of the 11 Neks. In the discussion, we return to the cross-connections among Neks and point out how our and other groups' functional and interactomics studies revealed that most Neks interact with protein partners associated with two if not all three of the functional contexts. We then raise the hypothesis that Neks may be the connecting regulatory elements that allow the cell to fine tune and synchronize the cellular events associated with these three core functions. The new and exciting findings on the Nek family open new perspectives and should allow the Neks to finally claim the attention they deserve in the field of kinases and cell cycle biology.

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