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1.
Cien Saude Colet ; 24(7): 2543-2555, 2019 Jul 22.
Artigo em Português, Inglês | MEDLINE | ID: mdl-31340272

RESUMO

AIDS is an advanced clinical manifestation of HIV infection. It generates severe immunodeficiency and associated infections that may lead to death. The antiretroviral therapy (ART) has reduced the morbimortality of HIV/AIDS, but its benefits depend on ART adherence. This integrative review followed the PICO method to identify factors associated with adult adherence to ART. Empirical papers published between January 2010 and December 2016 in the Medline, SciELO, Lilacs and PePSIC databases were included. We analyzed 125 papers regarding the characteristics of studies, adherence measures and associated factors. Results showed a wide variety in the definition of adherence and the use of measures for its monitoring, as well as several adherence-associated factors. These were categorized as follows: 1- Individual variables; 2- Treatment characteristics; 3- HIV/aids infection characteristics; 4- Relationship with the health services; 5- Social support. Health services should characterize the users' profiles, systematize adherence measures and regionally assess adherence-associated factors for the early detection of non-adherence to ART and implementation of effective intervention plans.

2.
Ciênc. Saúde Colet ; 24(7): 2543-2555, jul. 2019. tab, graf
Artigo em Português | LILACS-Express | ID: biblio-1011852

RESUMO

Resumo A AIDS é uma manifestação clínica avançada da infecção pelo HIV. Gera imunodeficiência grave e inúmeras infecções associadas, podendo levar à morte. A disponibilidade da Terapia Antirretroviral (TARV) diminuiu a morbi-mortalidade do HIV/AIDS, mas seus benefícios dependem da adesão ao tratamento. Esta revisão integrativa da literatura seguiu a estratégia PICO para identificar os fatores associados à adesão à TARV em adultos. Foram consultadas as bases Medline, SciELO, Lilacs e PePSIC e incluídos artigos publicados entre janeiro de 2010 e dezembro de 2016. Foram analisados 125 artigos, quanto às características dos estudos, medidas de adesão e fatores associados. Os resultados mostraram grande variação na definição da adesão e no uso das medidas para seu monitoramento, além de inúmeros fatores associados à adesão. Os quais foram agrupados nas categorias: 1. variáveis individuais; 2. características do tratamento; 3. características da infecção pelo HIV/AIDS; 4. relação com o serviço de saúde e 5. apoio social. É importante que os serviços caracterizem o perfil dos usuários, sistematizem as medidas de adesão e avaliem regionalmente fatores associados à adesão, para a detecção precoce da não adesão à TARV e estabelecimento de planos efetivos de intervenção.


Abstract AIDS is an advanced clinical manifestation of HIV infection. It generates severe immunodeficiency and associated infections that may lead to death. The antiretroviral therapy (ART) has reduced the morbimortality of HIV/AIDS, but its benefits depend on ART adherence. This integrative review followed the PICO method to identify factors associated with adult adherence to ART. Empirical papers published between January 2010 and December 2016 in the Medline, SciELO, Lilacs and PePSIC databases were included. We analyzed 125 papers regarding the characteristics of studies, adherence measures and associated factors. Results showed a wide variety in the definition of adherence and the use of measures for its monitoring, as well as several adherence-associated factors. These were categorized as follows: 1- Individual variables; 2- Treatment characteristics; 3- HIV/aids infection characteristics; 4- Relationship with the health services; 5- Social support. Health services should characterize the users' profiles, systematize adherence measures and regionally assess adherence-associated factors for the early detection of non-adherence to ART and implementation of effective intervention plans.

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