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1.
Int. j. pediatr. otorhinolaryngol ; 131: 1-29, Apr., 2020. ilus.
Artigo em Inglês | Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1052848

RESUMO

OBJECTIVE: To characterize the eating behavior, orofacial, speech myofunctional conditions, and facial temperature of children with congenital heart disease. METHOD: This is a cross-sectional and analytical study. The sample consisted of 30 children with heart disease (cyanotic or acyanotic; mean of 5.48 ± 0.84 years old) and 28 healthy children (4.98 ± 0.64 years old). Parents were given a questionnaire to assess eating behaviors (Montreal Children's Hospital Feeding Scale). The orofacial myofunctional assessment protocol (OMES-E), the Child Language Test (ABFW), and thermography infrared of facial temperature were used. Data analysis was conducted by student's t-tests, Chi-square, logistic regression, and correlation analysis. RESULTS: Eating behavior in Parents did not perceive eating behavior differences between the heart disease and control groups. However, the percentage of children with some feeding difficulty was higher in the heart disease group. There was a difference between groups regarding the appearance and posture of structures, the mobility of the mandibular and cheek, swallowing function, and the total function score. Thermographic variables did not differ between the groups, but better performance in orofacial functions correlated with the temperature of the labial commissure and lower lip points. CONCLUSIONS: The frequency of children with eating difficulties was higher among those with congenital heart disease, as was the increased facial temperature at the medial eyelid commission point when submitted to interventional procedures. The orofacial myofunctional aspects showed changes in posture and position, mobility, and orofacial functions among children with heart disease as compared to the control group. There was a correlation between the temperature of the thermo-anatomical points of the labial commissure and the lower lip as well as the OMES-E function score. (AU)


Assuntos
Fonoterapia , Sistema Estomatognático , Termografia , Comportamento Alimentar
2.
Arch Microbiol ; 2020 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-32034425

RESUMO

The current study aimed at the determination of the impact of obesity on the salivary microbiome in adolescents. Sixty subjects ranging 14-17 years old were enrolled (obese: n = 30-50% females, and normal weight: n = 30-50% females). Stimulated saliva was collected for denaturing gradient gel electrophoresis (DGGE) band patterns and massive 16S rRNA gene sequencing using the Ion Torrent platform. Overall, data analysis revealed that male subjects harbored a higher diverse salivary microbiome, defined by a significant higher richness (32.48 versus 26.74) and diversity (3.36 versus 3.20), higher Simpson values (0.96 versus 0.95) and distinct bacterial community structure considering either sex or condition (p < 0.05). Bacterial community fingerprinting analysis in human saliva showed a positive correlation with increased body mass index (BMI) in adolescents. Veillonella, Haemophilus and Prevotella occurrence was found to be affected by BMI, whereas Neisseria and Rothia occurrence was significantly impacted by sex in obese subjects. Our findings suggest that male and female adolescents may harbor a naturally distinct salivary microbiota and that obesity may specifically have an impact on their oral bacterial community. The potential dysbiotic oral microbiome in obese adolescents raises new insights on the etiology and prevention of future conditions in these populations.

3.
Int J Pediatr Otorhinolaryngol ; 131: 109883, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31968274

RESUMO

OBJECTIVE: To characterize the eating behavior, orofacial, speech myofunctional conditions, and facial temperature of children with congenital heart disease. METHOD: This is a cross-sectional and analytical study. The sample consisted of 30 children with heart disease (cyanotic or acyanotic; mean of 5.48 ± 0.84 years old) and 28 healthy children (4.98 ± 0.64 years old). Parents were given a questionnaire to assess eating behaviors (Montreal Children's Hospital Feeding Scale). The orofacial myofunctional assessment protocol (OMES-E), the Child Language Test (ABFW), and thermography infrared of facial temperature were used. Data analysis was conducted by student's t-tests, Chi-square, logistic regression, and correlation analysis. RESULTS: Eating behavior in Parents did not perceive eating behavior differences between the heart disease and control groups. However, the percentage of children with some feeding difficulty was higher in the heart disease group. There was a difference between groups regarding the appearance and posture of structures, the mobility of the mandibular and cheek, swallowing function, and the total function score. Thermographic variables did not differ between the groups, but better performance in orofacial functions correlated with the temperature of the labial commissure and lower lip points. CONCLUSIONS: The frequency of children with eating difficulties was higher among those with congenital heart disease, as was the increased facial temperature at the medial eyelid commissions point when submitted to interventional procedures. The orofacial myofunctional aspects showed changes in posture and position, mobility, and orofacial functions among children with heart disease as compared to the control group. There was a correlation between the temperature of the thermo-anatomical points of the labial commissure and the lower lip as well as the OMES-E function score.

4.
Nutr Res ; 74: 62-70, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31954275

RESUMO

As saliva showed to be a noninvasive source of markers useful to monitor clinical status, the hypothesis tested was that saliva may provide reliable markers able to predict the body fat accumulation in young subjects. The salivary characteristics of 248 adolescent scholars (119 girls; 14-17 years) of flow rate, pH, phosphorus, urea, and calcium concentrations were assessed in stimulated saliva (colorimetric automated technique). The concentrations of cholesterol, 7-ketocholesterol, 25-hydroxyvitamin D2 and D3, and uric acid (UA) were measured with high-performance liquid chromatography in saliva collected at home (12-hour fast). Physical examination included height, weight, and body fat percentage (%BF) measured using bioelectric impedance to classify groups in below/above the %BF cutoff. Data were evaluated using 2-way analysis of variance and multiple linear regression. No significant difference was found in the levels of 25-hydroxyvitamin D2 and D3, cholesterol, 7-ketocholesterol, phosphorus, calcium, and urea between groups above and below %BF cutoff, and the variation in salivary flow was small. Significant sex and group effects were observed for salivary UA, which was increased in adolecents with higher %BF and in males (compared to females), without sex group interaction (power = 99.8%). Sex showed a significant effect on salivary urea, with lower levels in females. A predictive model was obtained, with salivary UA and sex explaining the variation of %BF (P < .001; power = 84%). Salivary UA showed to be an important marker of body fat accumulation in adolescents, demonstrating the clinical relevance of saliva to detect early changes and to monitor the nutritional status using a noninvasive and accurate method.

5.
Acta Odontol Scand ; : 1-9, 2019 Nov 27.
Artigo em Inglês | MEDLINE | ID: mdl-31775545

RESUMO

Objective: The aim was to examine oral mechanical and gustatory sensitivities in adult smokers and to estimate salivary levels of cotinine by tobacco consumption. A total of 54 adults (20-45 years old; 28 males/26 females) were divided into two sex-paired groups: smoker group (n = 27), tobacco consumers with no other chronic disease/use of chronic medication, and a control non-smoker non-exposed group with similar age (n = 27).Materials and Methods: 24 h-Recall was used to gather information about tobacco consumption, date of onset and duration of the habit. Oral mechanical evaluation comprised touch detection threshold (MDT) of upper and lower lips and tongue tip and two-point discrimination (TPD) assessments. Taste sensitivities for sweet, salty, sour and bitter were evaluated in four concentrations. Salivary cotinine was determined by high performance liquid chromatography. Statistical analysis comprised Mann-Whitney, Two-way ANOVA test and regression analysis.Results: The mean smoking time was 13.6 years (mean 8.4 mg/day; 13 cigarettes/day). A sex-effect was observed on MDT of tongue tip (higher sensitivity in females), while group-effect was observed on TPD of lower lip, showing a smaller sensitivity among smokers (p < .05; moderate effect: Eta partial2 = 0.076). Although the total score of gustatory sensitivity did not differ between groups, smokers exhibited an irregular pattern of correctly identified tastants among the different concentrations of salty, sour and bitter. The predictive model showed that salivary cotinine was dependent on "nicotine consumption on the day before" (R2 = 49%).Conclusion: A difference in tactile sensitivity of the lower lip and qualitative changes in taste sensitivity were observed in smokers.

6.
Medicine (Baltimore) ; 98(38): e17193, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31567965

RESUMO

BACKGROUND: Sleep bruxism is a masticatory muscle activity characterized as rhythmic (phasic) or nonrhythmic (tonic). In children and adolescents, etiological factors, such as breathing pattern and sleep quality, have recently been addressed in studies investigating sleep bruxism. New therapies for adults, such as botulinum toxin, have been investigated, but such techniques are not applicable for individuals in the growth and development phase. METHODS: The participants will be 76 children, which will be randomly allocated to a control group, that is group 1, absence of bruxism; group 2, children with bruxism treated with infrared light-emitting diode (LED); and group 3, bruxism treated with occlusal splint. All participants will be submitted to a clinical evaluation to evaluate muscle activity and salivary biomarkers, before and after treatments. Muscle activity will be verified by electromyography of muscles mastication, masseter and temporal, and salivary biomarkers observed will be cortisol and dopamine levels. DISCUSSION: Photobiomodulation therapy has piqued the interest of researchers, as this noninvasive method has demonstrated positive results in problems related to muscle tissues. This document describes the protocol for a proposed study to evaluate morphological and psychosocial aspects in children and adolescents with awake bruxism and their responses to photobiomodulation therapy with infrared LED. CLINICAL TRIALS:.


Assuntos
Terapia com Luz de Baixa Intensidade/métodos , Bruxismo do Sono/radioterapia , Criança , Protocolos Clínicos , Humanos , Raios Infravermelhos/uso terapêutico , Músculos da Mastigação/fisiopatologia , Músculos da Mastigação/efeitos da radiação , Placas Oclusais , Bruxismo do Sono/fisiopatologia , Bruxismo do Sono/terapia
7.
J Texture Stud ; 50(3): 248-256, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30834535

RESUMO

As sucking habits and eating behavior may be interrelated and also associated with taste, body composition, and sociodemographic factors, the objective was to perform an exploratory analysis to identify groups of children with a high degree of association between intragroup subjects, providing explanation and interpretation of the data. The study initially included 352 prepubertal children (197 girls; 7- to 11-year-old), from whom information about sociodemographic characteristics, duration of breastfeeding, past bottle-feeding and non-nutritive sucking habits, taste sensitivity, body mass index (BMI), and consistency of food ingested were collected. Salivary concentrations of amylase and total protein were also determined. Data were submitted to cluster analysis (hierarchical analysis, K-means, and silhouette plot), one-way ANOVA and correlation tests. Cluster analysis included 159 children, generating three reliable and meaningful clusters: Cluster 1 (labeled "good tasters"), was characterized by older children and higher taste sensitivity; Cluster 2 ("softer food consistency") by longer bottle-feeding duration and children who eat food with lower consistency, and Cluster 3 ("breastfed") by longer breastfeeding duration (silhouette coefficient = 0.61). Cluster 3 also showed the higher percentage of normal-weight children, normal delivery, maternal schooling, and lower rate of past non-nutritional sucking habit. No correlation was found between salivary amylase and total protein concentrations, taste sensitivity and BMI, although taste sensitivity showed to be higher among girls (p = 0.002; power = 88%). The study identified three clusters, highlighting the relationship between nutritional sucking habits, consistency of food ingested, and sociodemographic characteristics. Most importantly, a close relation between bottle-feeding and consumption of soft food consistency was observed.

8.
J Oral Rehabil ; 46(7): 640-646, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30868605

RESUMO

BACKGROUND: Spherical shape and connecting bypass screw of the OT Equator abutment (Rhein83, Italy) provides several retentive possibilities, even in non-parallel implants. OBJECTIVE: This study assessed the long-term survival of standard-length and short implants receiving this multifunctional abutment. METHODS: Partially, edentulous patients (44 males and 64 females) (mean age 58.2 ± 10.5 years) rehabilitated with a fixed implant-supported prosthesis where the OT Equator abutments (Rhein83) were applied. Follow-up evaluations were performed up to 5 years following prosthesis delivery. Kaplan-Meier survival analysis and Cox regression analysis were used to determine whether the distribution of time to failure differed based on implant characteristics (length and region), adjusting for sex (α = 0.05). RESULTS: In total, 216 implants (5 × 8 mm, n = 126; 5 × 6 mm, n = 90) (Betwice, Mech & Human, Italy) were installed. The average follow-up period was 25.3 months (±19.3 months). Eight failures occurred, with most observed before loading (n = 6). Cumulative survival rates (CSR) at implant and abutment levels were 94.3% and 97.1%, respectively. Regarding implant length, CSRs were 97.8% and 90.6% for short and standard-length implants, respectively, with no difference between subgroups (logrank: χ2  = 1.34, df = 1, P = 0.25). No significant difference was also found between implants of maxilla (CSR = 92.2%) and mandible (CSR = 95.5%; logrank: χ2  = 0.08, df = 1, P = 0.78). CONCLUSION: The OT Equator abutment (Rhein83) showed a stable clinical performance, with continuous and predictable survival.


Assuntos
Implantes Dentários , Prótese Dentária Fixada por Implante , Idoso , Dente Suporte , Planejamento de Prótese Dentária , Falha de Restauração Dentária , Feminino , Seguimentos , Humanos , Itália , Masculino , Pessoa de Meia-Idade , Análise de Sobrevida , Resultado do Tratamento
9.
Physiol Behav ; 204: 93-99, 2019 05 15.
Artigo em Inglês | MEDLINE | ID: mdl-30776379

RESUMO

The use of smartphones during meals may possibly influence the number of ingested calories. We evaluated the influence of smartphones' distraction during eating on caloric intake. Physical (masticatory parameters, sex and body mass index - BMI); environmental (with or without distraction) and psychological (stress levels) variables were evaluated as confounding factors. Sixty-two adults were recruited for experimental snack tests performed on four different days. At baseline, we evaluated masticatory performance, swallowing threshold, masticatory frequency and body mass index (BMI). In the following three sessions, volunteers were presented a snack test in which participants ate under three experimental conditions: no distraction, using their smartphones, or reading a printed text. At the end of each session, total and nutritional compound stratified caloric intake was measured. Three-way mixed model ANOVA was used to test the effect of experimental condition on the total, carbohydrate and lipid caloric intakes. Hierarchical multiple linear regression models were used to estimate the influence of confounding factors on the total caloric intake. We found an effect of the condition (no distraction, smartphone or reading) on the total caloric (p = .007) and lipid intake (p = .002). When eating without distraction, the mean caloric intake was 535 (±164) kcal, in comparison to 591 (±203) kcal using smartphone (p = .05) and 622 (±226) kcal (p = .002) reading a text (no significant difference between distracters). Eating with distracters increased approximately 15% caloric ingestion. An interaction condition*sex effect was observed on lipid intake (p = .020). Energy intake was found to be dependent on sex and age, in which older men ingested more calories. Smartphone use during a meal increased caloric and lipid intake, depending on sex and age in young adults with complete dentition.

10.
J Oral Rehabil ; 46(6): 533-540, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30809826

RESUMO

BACKGROUND: Difficulties and limitations on masticatory function are among the main reasons why patients with temporomandibular disorder (TMD) seek care. OBJECTIVE: To evaluate the masticatory behaviour and perception of chewing difficulties in adults with mild TMD of recent onset, considering the presence of malocclusion. METHODS: Eighty-one young adults were divided into groups according to the presence of TMD and malocclusion: Non-TMD Normal Occlusion (n = 18), Non-TMD Malocclusion (n = 22), TMD Normal Occlusion (n = 18) and TMD Malocclusion (n = 23). TMD was assessed using the TMD Research Diagnostic Criteria and volunteers also answered questionnaires regarding their perception about jaw functional limitation and difficulty to chew foods of different textures. Masticatory and swallowing behaviours were assessed using the Orofacial Myofunctional Evaluation with Scores (OMES) protocol. Chewing time and chewing frequency taken to ingest the test-food were also obtained. Two-way-ANOVA was used to analyse the TMD, occlusion and TMD × occlusion interaction effects. RESULTS: Temporomandibular disorder effect was observed on vertical jaw mobility and jaw function limitation total scores, meaning that groups differed in the perception of opening limitation and mandibular limitation according to TMD status with a medium effect size. Also, more changes in chewing function (OMES-chewing score) and higher chewing frequency was observed in the presence of TMD (P < 0.05). Occlusion effect was only observed on OMES-swallowing score and no TMD × occlusion interaction effect was observed. CONCLUSION: Changes in chewing behaviour, frequency and perception of mandibular limitation was observed in the presence of TMD, pointing out the importance of functional evaluation when planning and establishing a treatment plan.


Assuntos
Mastigação , Transtornos da Articulação Temporomandibular , Deglutição , Oclusão Dentária , Humanos , Mandíbula , Adulto Jovem
12.
Arch Oral Biol ; 97: 191-197, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30396037

RESUMO

OBJECTIVE: Although atraumatic restorative treatment (ART) is considered to be a good option for anxious patients, there is a lack of information whether ART associated to oral health educational strategy (OHES) would positively influence the level of anxiety and stress in children. This study aimed to evaluate the impact of OHES on anxiety and stress markers of schoolchildren submitted to ART. DESIGN: A sample of 78 six- to eight-year-old schoolchildren, with carious lesions in dentin, were randomly divided into groups: OHES + ART-group (n = 39) and ART-group (n = 39). OHES consisted of an educational interactive strategy performed once a week for four weeks. ART was performed using a standardized procedure with hand instruments and glass-ionomer cement. Anxiety and stress markers were assessed subjectively by the modified Venham Picture Test (m-VPT), modified Venham Anxiety Scale (m-VAS), while objective measures consisted of heart rate (HR) and salivary cortisol and alpha-amylase levels evaluated before, during and after treatment. RESULTS: The two groups did not differ in the perceived anxiety and in anxious behavior, and the variation along the treatment was not significant in both groups (p > 0.05). Both groups also showed higher HR "Before ART-restoration" than the other time-points as an anticipatory anxiety. ART group showed higher HR than OHES + ART group during the "Explanation of procedure" (p = 0.041) and "Deep excavation" (p = 0.018), and only ART group showed higher amylase levels "Before ART" compared to "After ART" (p = 0.004). CONCLUSIONS: It was concluded that OHES associated with ART showed a positive effect in modulating heart rate and alpha-amylase levels, that is, those markers of stress objectively measured during ART-restoration.


Assuntos
Ansiedade ao Tratamento Odontológico/diagnóstico , Tratamento Dentário Restaurador sem Trauma/psicologia , Educação de Pacientes como Assunto , Estresse Psicológico/diagnóstico , Biomarcadores/análise , Criança , Feminino , Frequência Cardíaca/fisiologia , Humanos , Masculino , alfa-Amilases/metabolismo
13.
J Texture Stud ; 50(1): 45-52, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30561102

RESUMO

The aim of this study was to assess the differences in salivary biomarker levels of young adults classified according to body fat accumulation. One hundred and thirty-four volunteers were evaluated (mean age 21 ± 2 years). Body composition was calculated through skinfold thickness: supra-iliac, biceps, and triceps, sub-scapular. Body fat percentage (BF%) was used to classify subjects according to fat tissue accumulation: normal-weight (n = 37, 19 females, 18 males), overweight (n = 42, 30 females, 12 males), and obese (n = 55, 42 females, 13 males). Saliva samples were collected 30 min after awakening to determine salivary levels of 17-beta-estradiol. For salivary cortisol and alpha-amylase activity (sAA) three samples were obtained, just after awakening, 30 min after awakening and at bedtime. Oral contraceptive intake was considered for the female group. The results showed that overweight and obese females using oral contraceptive presented lower levels of 17-ß-estradiol than normal-weight females. In overweight and obese males, sAA levels were higher 30 min post-awakening when compared with the normal-weight group. The comparison of sAA levels within time showed no difference for males; obese females showed significant higher values at bedtime than 30 min post-awakening. The salivary cortisol concentration showed higher values at morning decreasing significantly at bedtime for all groups. Concluding, differences in 17-ß-estradiol and sAA levels were found in females and males, respectively, according to body fat accumulation, showing the usefulness of salivary biomarkers in the study of systemic conditions. PRACTICAL APPLICATIONS: Saliva is an advantageous biological fluid in innovative methods for diagnosis. Besides being a noninvasive method, salivary steroid measurements have the potential to provide a convenient assessment of serum free steroid concentrations.

14.
Child Obes ; 14(8): 501-509, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30183336

RESUMO

BACKGROUND: The aim of the present study was to undertake a systematic review exploring the relationship between childhood obesity and fecal microorganisms, to answer the following question: "Are Firmicutes and Bacteroidetes a significant risk indicator/factor for obesity in children?" The main search terms were "child" and "obesity" together with "gut microbiota" (PubMed: 2005-2017). The minimal requirements for inclusion were the evaluation of gut microbiota composition and BMI in children between 0 and 13 years of age. METHODS: Assessed articles were carefully classified according to a predetermined criterion, and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were considered. Seven articles were critically appraised and used as a basis for conclusions. RESULTS: Three studies showed a positive association between Bacteroides fragilis and obesity. In addition, a high value of evidence indicated that a decrease in the Bacteroidetes phylum and in Bacteroides/Prevotella groups was related to high BMI. For the Firmicutes phylum, one high-quality study highlighted that it was positively correlated with weight gain. With regard to Firmicutes species, Clostridium leptum, Eubacterium hallii, and Lactobacillus spp. indicated adipose tissue storage, while Clostridium difficile and the Staphylococcus genus were correlated with low BMI. Despite the fact that only one study did not perform real-time polymerase chain reaction to quantify the microorganisms, its results corroborated those of the studies that did. CONCLUSIONS: Changes in Firmicutes and Bacteroidetes phyla/species levels might in fact be significant indicators/factors for childhood obesity. However, given the small number of articles appraising these entire phyla and the heterogeneity among the species assessed, further well-designed studies are required to improve the knowledge.


Assuntos
Bacteroidetes , Firmicutes , Microbioma Gastrointestinal , Obesidade Pediátrica/epidemiologia , Obesidade Pediátrica/microbiologia , Criança , Pré-Escolar , Humanos , Lactente
15.
Physiol Behav ; 184: 220-225, 2018 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-29217358

RESUMO

The evaluation of mastication is important to understand the masticatory behavior and diagnose feeding difficulties. The objective of this preliminary study was to verify if there is agreement between objective and subjective validated methods of chewing evaluation in a convenience sample which consisted of 32 adolescents (mean 15.5years), complete permanent dentition and free of tooth decay. The Quality of Masticatory Function Questionnaire with the Food-Mastication, Habits, Meat, Fruit and Vegetables domains was used in the subjective evaluation. The objective aspects consisted of maximum bite force (BF) and masticatory performance (MP) by mastication of cubes of test-material and sieving to determine the median particle size (X50) and distribution in the sieves ("b"), and by the colorimetric method using colorchangeable chewing gum. Data were submitted to exploratory analysis, normality test and correlation tests (Pearson/Spearman). The correlation between BF and X50 (r=-0.43; p=0.02) and between BF and MP chewing gum (r=0.53; p=0.002) was significant with large effect size. The MP evaluated by chewing gum correlated with X50 (r=-0.34; p=0.055), but not with "b" (r=-0.06; p=0.73), while "b" correlated only with X50 (r=0.52, p=0.002). No significant correlation was observed between the objective measures and the total score of the subjective evaluation; only a negative correlation was observed between "b" and Meat domain (r=-0.40; p=0.023). The objective methods showed moderate correlation with each other and no agreement between the objective and subjective methods was observed in this sample of healthy adolescents, emphasizing the importance of both aspects in the evaluation of masticatory function.


Assuntos
Força de Mordida , Mastigação/fisiologia , Adolescente , Goma de Mascar , Feminino , Humanos , Masculino , Reprodutibilidade dos Testes , Estatística como Assunto , Inquéritos e Questionários
16.
Rev. bras. ciênc. saúde ; 22(3): 247-254, 2018. tab
Artigo em Português | LILACS | ID: biblio-946570

RESUMO

Objetivo: o objetivo deste estudo foi avaliar a relação entre fatores socioeconômicos e o excesso de peso em escolares da rede pública do município de Carapicuíba (SP, Brasil). Material e Métodos: Foram incluídas 355 crianças (176 de cinco anos e 179 de 12 anos), selecionadas por amostragem aleatória simples, para a coleta das variáveis em estudo: sexo, escolaridade dos pais, renda familiar bruta, número de cômodos da casa e número de pessoas que habitavam o domicílio. O exame físico envolveu as medidas de peso, estatura e cálculo do índice de massa corporal (IMC) para a classificação das crianças em magreza severa, magreza, eutrofia, sobrepeso e obesidade (OMS, 2007). Os dados foram analisados por estatística descritiva, testes Quiquadrado, Kruskal-Wallis e correlação de Spearman. Resultados: Foram observados índices de excesso de peso e obesidade de 26,7% e 10,8% aos cinco anos, e 21,8% e 8,9% aos 12 anos, respectivamente. Os índices observados no grupo de cinco anos foram inferiores, enquanto os observados no grupo de 12 anos foram superiores aos índices nacionais. No grupo de cinco anos, o número de cômodos dos lares de crianças com obesidade foi significativamente maior que o de crianças que apresentavam eutrofia (p=0,016); já no grupo de 12 anos, o IMC correlacionou-se positivamente com a escolaridade materna (r=0,163; p=0,040). Conclusão: Os fatores socioeconômicos relacionaram-se com a presença de excesso de peso em escolares do município de Carapicuíba (SP, Brasil), devendo esta condição ser avaliada e abordada por meio de políticas e estratégias públicas de saúde em suas múltiplas dimensões. (AU)


Objective: To evaluate the relationship between socioeconomic factors and overweight in children attending public schools in Carapicuíba, SP, Brazil. Material and Methods:The sample comprised 355 children (176 subjects 5years old, and 179 subjects 12years old), and the following variables were evaluated: sex, parental education, family income, number of rooms inthe household, and the number of people living in the household. Physical examination involved measurements of weight, height, and determination of the body mass index (BMI) to classify children into groups: severe underweight, underweight, normalweight, overweight and obesity. Data collected were analyzed using descriptive statistics, chi-square test, Kruskal-Wallis and Spearman correlation tests. Results:A prevalence of overweight and obesity of 26.7% and 10.8% in 5-year-old children, and 21.8% and 8.9% in 12-year-old children, respectively, was observed. The prevalence rates observed in 5-year-old children were lower than those of national surveys, whilethe rates observed among 12-year oldswerehigher. In the group of 5-year olds, the number of householdrooms of children with obesity was significantly higher than that of normalweight (p=0.016) subjects. In the group of 12-year olds, BMI was positively correlated with maternal education (r=0.163, p=0.040).Conclusion: It is therefore concluded that socioeconomic factors were related with overweight and obesity in schoolchildren from Carapicuíba, SP, Brazil. This condition should be evaluated and addressed through public health policies and strategies in its multiple dimensions. (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Obesidade Pediátrica , Criança , Fatores Socioeconômicos
17.
Braz Oral Res ; 31: e78, 2017 Sep 28.
Artigo em Inglês | MEDLINE | ID: mdl-29019550

RESUMO

The etiology of temporomandibular disorders (TMD), which are considered as a heterogeneous group of psychophysiological disturbances, remains a controversial issue in clinical dentistry. This study aimed to evaluate whether the salivary alpha-amylase (sAA), cortisol levels, and anxiety symptoms differ between children with and without TMD. Initially, 316 young subjects were screened in public schools (nonreferred sample); 76 subjects aged 7-14 years were selected and comprised the TMD and control groups with 38 subjects each matched by sex, age, and the presence/absence of sleep bruxism. Four saliva samples were collected: upon waking, 30 min and 1 h after awakening (fasting), and at night (at 8 PM) on 2 alternate days to examine the diurnal profiles of cortisol and sAA. Anxiety symptoms were screened using the Multidimensional Anxiety Scale for Children (MASC-Brazilian version). Shapiro-Wilk test, Student's t-test/Mann-Whitney U test, and correlation tests were used for data analysis. No significant differences were observed in the salivary cortisol area under the curve (AUCG mean ± SD = 90.22 ± 63.36 × 94.21 ± 63.13 µg/dL/min) and sAA AUCG (mean ± SD = 2544.52 ± 2142.00 × 2054.03 ± 1046.89 U/mL/min) between the TMD and control groups, respectively (p > 0.05); however, the clinical groups differed in social anxiety domain (t = 3.759; CI = 2.609, 8.496), separation/panic (t = 2.243; CI = 0.309, 5.217), physical symptoms (U = 433.500), and MASC total score (t = -3.527; CI = -23.062, -6.412), with a power of the test >80% and large effect size (d = 0.80), with no significant correlation between the MASC total score, cortisol, and sAA levels. Although children with TMD scored higher in anxiety symptoms, no difference was observed in the salivary stress biomarkers between children with and without TMD.


Assuntos
Transtornos de Ansiedade/metabolismo , Hidrocortisona/análise , Saliva/química , Transtornos da Articulação Temporomandibular/metabolismo , Transtornos da Articulação Temporomandibular/psicologia , alfa-Amilases/análise , Adolescente , Transtornos de Ansiedade/complicações , Biomarcadores/análise , Estudos de Casos e Controles , Criança , Dor Facial/psicologia , Feminino , Humanos , Masculino , Valores de Referência , Fatores de Risco , Estatísticas não Paramétricas , Estresse Fisiológico , Transtornos da Articulação Temporomandibular/etiologia , Escala de Ansiedade Frente a Teste , Fatores de Tempo
18.
Anticancer Res ; 37(8): 4017-4024, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-28739683

RESUMO

Genotoxicity is the capacity of an agent to produce damage in the DNA molecule. Considering the strong evidence for a relationship between genetic damage and carcinogenesis, evaluation of genotoxicity induced by dental materials is necessary for elucidating the true health risks to patients and professionals. The purpose of this article was to provide a comprehensive review of genotoxicity induced by dental materials. All published data showed some evidence of genotoxicity, especially related to dental bleaching, restorative materials and endodontic compounds. Certainly, such information will be added to that already established for regulatory purposes as a safe way to promote oral healthcare and prevent oral carcinogenesis.


Assuntos
Carcinogênese/genética , Dano ao DNA/efeitos dos fármacos , Materiais Dentários/efeitos adversos , Carcinogênese/efeitos dos fármacos , Dano ao DNA/genética , Materiais Dentários/uso terapêutico , Humanos
19.
Arch Oral Biol ; 82: 62-70, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28601734

RESUMO

OBJECTIVE: The purpose was to evaluate the effect interocclusal appliance therapy on bite force (BF), sleep quality and salivary cortisol levels in adults with SB diagnosed by polysomnography. As a secondary aim, signs and symptoms of temporomandibular dysfunction (TMD) were evaluated. DESIGN: Forty-three adults (19-30 y/o) were divided into two groups: experimental group (GSB), composed of 28 subjects with SB, and control group (GC), without SB and TMD (n=15). GSB was treated with stabilization interocclusal splint and evaluated at time intervals: before (baseline), one month (T1) and two months (T2) after therapy began, to collect data related to BF, sleep quality (Pittsburgh Sleep Quality Index), salivary cortisol levels and TMD. GC was also examined three times and received no therapy. Data were analysed by means of normality tests, t-test/Mann-Whitney and One-way ANOVA repeated measures (Tukey post-test). Two-way ANOVA test for repeated measures was applied to verify the effect time*group interaction on the variance of each dependent variable (α=0.05). RESULTS: GSB showed an increase in BF and a positive effect on muscular symptomatology, range of mandibular movements and sleep quality; in GC these parameters did not differ. Cortisol concentration decreased between baseline and T1 in GSB (F(1,31)=4.46; test power=62%; p=0.017). The variance observed for BF, TMD and sleep quality among time points was dependent on the group (moderate effect size: partial Eta square >0.16; test power >80%). CONCLUSIONS: The results suggested that short-term interocclusal appliance therapy had a positive effect on BF, temporomandibular symptomatology, sleep quality and salivary cortisol levels in adults with SB.


Assuntos
Força de Mordida , Hidrocortisona/análise , Placas Oclusais , Saliva/química , Bruxismo do Sono/prevenção & controle , Bruxismo do Sono/fisiopatologia , Transtornos da Articulação Temporomandibular/prevenção & controle , Transtornos da Articulação Temporomandibular/fisiopatologia , Adulto , Feminino , Humanos , Estudos Longitudinais , Masculino , Polissonografia
20.
Braz. dent. sci ; 20(2): 38-46, 2017. ilus, tab
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-837449

RESUMO

Objetivos: Para compreender melhor a relação entre má oclusão e as funções mastigatória e salivar na dentição decídua, objetivou-se avaliar as diferenças na performance mastigatória (PM), morfologia facial (MF), força de mordida (FM) e parâmetros salivares em 65 pré-escolares com oclusão normal (n = 22), mordida cruzada funcional posterior (n = 20) e mordida aberta anterior (n = 23) e explorar a relação entre essas variáveis. Materiais e Métodos: PM, MF e FM foram avaliados pelo método de peneiragem, antropometria e gnatodinamômetro, respectivamente. O fluxo salivar estimulado (SE) e não estimulado (SNE) e composição salivar foram mensurados por técnica colorimétrica automatizada. Os dados foram analisados utilizandose ANOVA/Kruskal-Wallis, teste-t/Wilcoxon e teste de correlação de Pearson/Spearman. A relação entre fluxo salivar e as demais variáveis independentes foi avaliada por regressão linear múltipla. Resultados: A dimensão facial inferior foi menor no grupo com mordida cruzada e observou-se menor FM no lado cruzado do arco dentário. A FM correlacionou-se positivamente com a largura intergoníaca no grupo com mordida aberta. Nos grupos com má oclusão, uma melhor PM relacionou-se com as larguras bizigomática e intergoniana. O fluxo de SNE foi menor no grupo com mordida cruzada e a concentração de proteína total diferiu entre SE e SNE apenas no grupo com mordida cruzada, sendo menor na SNE. A atividade da amilase foi maior na SE em relação à SNE em todos os grupos. O fluxo de SE mostrou relação positiva com a idade e negativa com a presença de maloclusão. Conclusão: Em crianças de pouca idade foram encontradas correlações significativas entre os parâmetros mastigatórios e as dimensões faciais; além disso, parâmetros mastigatórios e salivares importantes diferiram entre crianças com diferentes tipos de oclusão, mostrando a importância da avaliação precoce destes parâmetros.(AU)


Objective: To better understand the relationship between malocclusion and masticatory and salivary functions in the primary dentition, the aim was to evaluate the differences in masticatory performance (MP), facial morphology (FM), maximal bite force (BF) and salivary parameters in 65 preschool children with normal occlusion (n = 22), functional posterior crossbite (n = 20) and anterior open bite (n = 23), and to explore the relationship between these variables. Material and Methods: MP, FM and BF were assessed by sieving method, anthropometry and gnatodynamometer, respectively. Stimulated (SS) and unstimulated (US) saliva flow and composition were measured by automated colorimetric technique. Data were analyzed using ANOVA/Kruskal-Wallis, t-test/Wilcoxon and Pearson/Spearman correlation test. The relationship between SS flow rate and the independent variables were assessed using multiple linear regression. Results: The lower face dimension was smaller in crossbite-group, and a decreased BF in the crossbite-side of the dental arch was observed. BF correlated positively with intergonial width in open bite group. In malocclusion groups, better MP correlated with byzigomatic and intergonial widths. US flow rate was lower in crossbite-group and total protein concentration differed between SS and US saliva only in the crossbite-group, being lower in US. Amylase activity was higher in SS than US in all groups. SS flow rate related positively with age and negatively with the presence of malocclusion. Conclusion: In young subjects, significant correlations were found between masticatory parameters and facial dimensions; in addition, some important masticatory and salivary parameters differed between children with diferent morphological occlusions, hence the importance of the early assessment of these parameters.(AU)


Assuntos
Humanos , Força de Mordida , Oclusão Dentária , Dentição , Sistema Estomatognático
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