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1.
Arch. Clin. Psychiatry (Impr.) ; 46(3): 72-79, May.-June 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1011151

RESUMO

Abstract Background Mild Cognitive Impairment (MCI) is a disorder in which the patient presents a cognitive decline, but without negative impact on the activities of daily living. Objective To carry out a systematic review of published studies that analyzed the prevalence of Mild Cognitive Impairment (MCI) in older adults living in the community, and the criteria used for the diagnosis of this disorder. Methods A search was carried out in May 2017 using the descriptors: "epidemiology" or "prevalence", "mild cognitive impairment", and "community" in the PubMed, PsycInfo, SciELO, Web of Science, and Scopus databases. Two independent researchers extracted and documented the data. We used a random effect model to calculate pooled prevalence of MCI for overall studies and for each subgroup divided by diagnostic criteria. Results We found initially 1996 articles, and we selected 35 studies. The prevalence of MCI in the selected studies ranged from 0.5% to 41.8%. The overall pooled prevalence of MCI was 17.3% (CI 95%, 13.8-20.8), with significant heterogeneity between estimates (I2 = 99.6%). Discussion The standardization of the diagnostic criteria for MCI, as well as the tests used in the cognitive evaluation, could allow the comparison between the studies and would be an important step in the researches of this area.

3.
Front Psychiatry ; 9: 5, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29472873

RESUMO

Introduction: Music performance anxiety (MPA) can be defined as a lasting and intense apprehension connected with musical performance in public. Studies suggest that MPA can be regarded as a subtype of social anxiety. Since individuals with social anxiety have deficits in the recognition of facial emotion, we hypothesized that musicians with high levels of MPA would share similar impairments. Objective: The aim of this study was to compare parameters of facial emotion recognition (FER) between musicians with high and low MPA. Methods: 150 amateur and professional musicians with different musical backgrounds were assessed in respect to their level of MPA and completed a dynamic FER task. The outcomes investigated were accuracy, response time, emotional intensity, and response bias. Results: Musicians with high MPA were less accurate in the recognition of happiness (p = 0.04; d = 0.34), had increased response bias toward fear (p = 0.03), and increased response time to facial emotions as a whole (p = 0.02; d = 0.39). Conclusion: Musicians with high MPA displayed FER deficits that were independent of general anxiety levels and possibly of general cognitive capacity. These deficits may favor the maintenance and exacerbation of experiences of anxiety during public performance, since cues of approval, satisfaction, and encouragement are not adequately recognized.

4.
Arch Gerontol Geriatr ; 74: 83-87, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29040889

RESUMO

OBJECTIVE: The aim of the present study was to evaluate factors associated with happiness in a sample of Brazilian older adults. METHODS: A study was conducted with 263 elderly people in the area of coverage of a family health unit located in the state of São Paulo, Brazil. The Subjective Happiness Scale was used to measure happiness, the final score of which determined one of three outcomes: not happy, intermediate, and happy. Disability, sociodemographic characteristics, and psychological, cognitive, and physical factors were considered for the multinomial logistic regression analysis. RESULTS: Statistically significant differences were found among the three groups regarding satisfaction with life, disability, social phobia, anxiety, depression, and frailty (p≤0.05). In the multinomial regression analysis, being "not happy" was significantly associated with satisfaction with life (RRR: 0.53), depression (RRR: 1.46), social phobia (RRR: 1.24), and age (RRR: 1.06). CONCLUSION: The present findings indicate that psychological factors and age influence the levels of happiness in older adults living in the community. Furthermore, better screening, diagnosis, and treatment of mental health disorders could increase the feeling of happiness among older adults.


Assuntos
Felicidade , Idoso , Idoso de 80 Anos ou mais , Depressão/psicologia , Feminino , Humanos , Vida Independente , Modelos Logísticos , Masculino , Satisfação Pessoal
5.
Rev. psiquiatr. clín. (São Paulo) ; 44(4): 85-88, July-Aug. 2017. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-903033

RESUMO

Abstract Background Among non-motor symptoms of Parkinson's disease (PD), anxiety occurs in up to 67% of patients. Clinically, PD patients report worsening of tremors in anxiogenic situations. Objective The aim of this study was to evaluate the association between motor symptoms and anxiety in PD patients and compare their performances with those of healthy volunteers. Methods Fifteen volunteers with PD and 15 healthy volunteers without clinically significant psychiatric disorders were evaluated. Both groups were subjected to a simulated public speaking test (SPST). The following parameters were measured: visual analog mood scale (VAMS), items related to tremors of UPDRS, bradykinesia tests, blood pressure, and heart rate. Results Results of repeated measures ANOVA indicated a significant effect on group × phase interaction (F3.7,105.6 = 2.56; p = 0.046) for VAMS anxiety factor. Regarding tremors, ANOVA indicated significant differences in group × phase interaction (F4.5,121 = 2.88; p = 0.021) and between the groups (F1,27 = 45.88, p < 0.001), with differences in the anticipatory phase, performance, and post-speech, compared with those in the baseline. There were no significant differences between the groups with regard to other factors of VAMS, physiological measurements, and bradykinesia. Discussion Worsening of tremors occurred during SPST, particularly in phases with higher anxiety scores.

7.
J Psychiatr Res ; 90: 40-45, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28222355

RESUMO

Depression is the most common psychiatric disorder in Parkinson's disease (PD). The aim of this study was to compare PD patients with current Major Depressive Disorder (MDD), lifetime MDD, and no MDD using three neuroimaging techniques. A total of 43 PD patients were selected and divided into three groups: (i) current MDD (n = 15), (ii) previous MDD without current MDD (n = 10); and (iii) control group (no current or lifetime MDD; n = 18). All participants underwent magnetic resonance imaging to evaluate cortical thickness, cortical and subcortical volume, and spectroscopy in the bilateral putamen and cingulate cortex. Volumetric analysis showed volume decreases in frontal and temporal areas, bilateral amygdala, and left cerebellar white matter in the lifetime MDD group compared to the control group. Furthermore, the volumes of the anterior cingulate cortex, right amygdala, and left cerebellar white matter were smaller in the group with current MDD compared to the control group. Regarding cortical thickness, the left rostral anterior cingulate gyrus of the group with previous MDD was thinner compared to the control group. There was a weak negative correlation between the NAA/Cre ratio in the right putamen and depressive symptoms. The results suggested current and lifetime MDD have a negative impact on the neurodegenerative process of PD, with decreased volume and/or reduction of cortical thickness in temporal and frontal areas, anterior cingulate cortex, amygdala, and cerebellar white matter.


Assuntos
Encéfalo/diagnóstico por imagem , Transtorno Depressivo Maior/diagnóstico por imagem , Transtorno Depressivo Maior/etiologia , Doença de Parkinson/complicações , Espectroscopia de Prótons por Ressonância Magnética , Adulto , Idoso , Encéfalo/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Substância Branca/diagnóstico por imagem
8.
Rev. psiquiatr. clín. (São Paulo) ; 44(1): 23-29, Jan.-Feb. 2017. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-845828

RESUMO

Abstract Background Secondary interventions are implemented within a short interval following the occurrence of traumatic events with the purpose of preventing the onset of PTSD. Objective Analyze the results of studies that assessed post-trauma interventions in adults aimed at preventing the onset of PTSD or symptoms related to PTSD. Methods We performed literature searches using the search expression [(Early intervention OR secondary prevention) AND (Post traumatic stress disorder OR PTSD)] for articles published until October 2016. Among the references found, 29 fulfilled the selection criteria established for the review. Data were divided and analyzed according to the type of intervention: pharmacological or psychological. Results Psychological measures used in the studies lack homogeneity regarding the type of intervention and the assessment of intervention outcomes. Pharmacological interventions were less frequent and findings require replication, together with an expansion in the types of substances investigated. In general, many of the studies reviewed suggest that both pharmacological and psychological interventions are effective in the prevention of PTSD. Discussion Future trials should be focused on determining the best interventions for the secondary prevention of PTSD. The combination of psychological and pharmacological interventions for post-trauma patients poses opportunities and challenges that remain unexplored.

9.
Rev. psiquiatr. clín. (São Paulo) ; 44(1): 10-19, Jan.-Feb. 2017. tab
Artigo em Inglês | LILACS-Express | ID: biblio-845829

RESUMO

Abstract Background DSM-5 introduced some modifications on Posttraumatic Stress Disorder (PTSD) criteria. The instruments developed for the assessment of aspects related to PTSD needed a reformulation, as was the case of the Posttraumatic Stress Disorder Checklist (PCL). Objectives To present the process of transcultural adaptation of the three forms of the PCL-5 to Brazilian Portuguese, as well as its face validity. Methods The procedure involved independent translations, a synthesis version, back translation by an independent translator, evaluation by the original author, analysis by an expert committee, and a pretesting study (10 subjects with/without experience of a traumatic situation). The last two steps formed the face validity procedure. Results The synthesis version was approved by the original author and the agreement percentage by the expert committee was excellent, with only two items showing < 90%. The pretesting study showed that the Brazilian version was well understood and linguistically and culturally accepted by the participants, which did not make significant suggestions for changes. Discussion Transcultural adaptation of the PCL-5 for Brazilian Portuguese followed a rigid and standardized procedure. Therefore, after having its face validity assessed by an expert committee and by the target population, it is apt to be used.

10.
Rev. psiquiatr. clín. (São Paulo) ; 43(6): 139-142, Nov.-Dec. 2016. tab
Artigo em Inglês | LILACS | ID: biblio-830766

RESUMO

Abstract Background: Studies found inconsistent frequencies of social anxiety disorder (SAD) in Parkinson's disease (PD) (9.7%-50%). Previous reports did not test the impact of applying DSM-IV restrictive criteria that recommends the exclusion of secondary cases when diagnosing SAD in PD. Objective: Our aim is to estimate the frequency of social anxiety according to DSM-IV criteria and according to an inclusive broader approach. Methods: One hundred and ten PD patients were assessed for the presence of SAD using SCID-I, diagnosis of social anxiety were determined according to two different criteria: following and not following DSM-IV recommendation for exclusion of cases though to be secondary to a general medical condition. Results: SAD was present in 34 (31%) of patients, but 17 (15.5%) were secondary to a general medical condition. Patients with SAD were significantly younger, had earlier disease onset, had more severe PD symptoms, and were more frequently depressed. There was no difference in demographic and clinical features between primary and secondary SAD. Discussion: We conclude that the use of different diagnostic criteria may have a massive impact in the estimation of frequency of SAD in PD.


Assuntos
Humanos , Masculino , Doença de Parkinson/diagnóstico , Fobia Social
11.
Neurosci Biobehav Rev ; 71: 802-809, 2016 12.
Artigo em Inglês | MEDLINE | ID: mdl-27810346

RESUMO

Deficits in recognition of facial expressions of emotion (RFEE) play a central role in the manifestation of anxiety disorders (AD). We systematically reviewed the literature to determine effects of drugs used in AD treatment on RFEE, based on outcomes of accuracy rate, reaction time, and intensity. Electronic databases, including Pubmed, PsycINFO, and Scielo, were used without time constraints. Twenty-six clinical/experimental studies on healthy subjects, focusing on 11 drugs, published in English, Portuguese, and Spanish, were selected. We found that increased recognition of happiness was associated with acute use of citalopram, fluoxetine, duloxetine, and reboxetine. Increased and decreased recognition of negative emotions were associated with the use of selective serotonin and/or norepinephrine reuptake inhibitors, respectively. Benzodiazepine favored recognition of negative emotions. Differences in reaction time were rarely observed. Stimuli with distinct emotion intensities produced similar effects. Specific changes occurred in RFEE depending on the drug, its administration route and dose, and emotion valence. Evidences indicate significant effects on emotional processing relevant to clinical practice, particularly in treating patients with emotional disorders.


Assuntos
Transtornos de Ansiedade , Emoções , Expressão Facial , Humanos , Psicotrópicos , Recognição (Psicologia)
12.
J. bras. psiquiatr ; 65(3): 209-214, jul.-set. 2016. tab
Artigo em Português | LILACS-Express | ID: biblio-829093

RESUMO

RESUMO Objetivo Avaliar a empatia e a capacidade de reconhecimento de emoções básicas e complexas e suas correlações em estudantes de Medicina. Métodos O desenho do estudo foi transversal. Foram avaliados 86 alunos do 3º e 4º ano do curso de Medicina de uma faculdade de Medicina do interior do estado de São Paulo com os seguintes instrumentos: (i) escala Jefferson de empatia, (ii) tarefa de Reconhecimento de Expressões Faciais de emoções básicas (REF) e (iii) Reading the mind in the eyes test (RMEt). Resultados A média geral de acertos no REF foi 15,6 (DP: ±2,3). Houve diferença estatisticamente significante no número de acertos da emoção tristeza no sexo feminino comparado com o masculino (t84 = 2,30; p = 0,02). Em relação ao RMEt, a média geral de acertos foi de 26,5 (DP: ±3,3) com diferença estatisticamente significante entre os gêneros com maior número de acertos entre as estudantes do sexo feminino (t84 = 3,43; p < 0,01). O escore total médio na escala de empatia foi 121,3 (DP: ±9,8). Houve correlação positiva fraca entre o escore total da escala de empatia e o número de acertos para a emoção tristeza (r = 0,29; p < 0,01). Conclusão O número de acertos para a emoção tristeza no REF e o escore total do RMEt foi maior no sexo feminino comparado com sexo masculino. Além disso, a empatia parece estar diretamente relacionada com a capacidade de reconhecer a emoção tristeza. Outros estudos parecem pertinentes para avaliar de forma mais profunda aspectos de empatia e reconhecimento de expressões faciais da emoção em estudantes de medicina.


ABSTRACT Objective The aim was to evaluate empathy and facial expression recognition of basic and complex emotions and their correlations in medical students. Methods A cross-sectional study was performed in a medical school of the state of São Paulo. We evaluated 86 third and fourth year medical students with the following instruments: (i) Jefferson Scale of Empathy, (ii) Facial Expression Recognition of basic emotions task (REF) and (iii) Reading the Mind in the Eyes test (RMEt). Results The overall mean score in the REF was 15.6 (SD: ±2.3). There was a statistical significant difference in the number of correct responses in sadness emotion in female gender compared to male (t84 = 2.30; p = 0.02). Regarding RMEt, the overall mean score was 26.5 (SD: ±3.3) with statistically significant difference between genders with higher number of correct responses among female students (t84 = 3.43; p < 0.01). The mean score on the empathy scale was 121.3 (SD: ±9.8). There was significant weak positive correlation between the total score of empathy scale and the recognition of sadness facial emotion (r = 0.29; p < 0.01). Conclusion The number of correct responses to sadness emotion in the REF and the total score of RMEt was higher in female students compared to male. In addition, empathy seems to be directly related to the ability to recognize sadness. Other studies are needed to provide a deeper understanding of empathy and facial emotion recognition in medical students.

13.
J. bras. psiquiatr ; 65(1): 94-98, jan.-mar. 2016. tab
Artigo em Português | LILACS-Express | ID: lil-777349

RESUMO

RESUMO Objetivo Realizar uma revisão atualizada dos estudos que avaliaram o delirium como fator de risco para o desenvolvimento de demência em idosos. Métodos A revisão foi realizada utilizando-se a base de dados do PubMed, com o seguinte cruzamento de descritores: risk factors and (delirium or acute confusional state) and dementia. Apenas estudos do tipo coorte publicados entre janeiro de 2000 a maio de 2015 foram considerados. Resultados Foram selecionados oito estudos de acordo com os critérios de inclusão e exclusão. Todos os estudos apontaram para um aumento do risco de demência ou declínio cognitivo após a ocorrência de delirium, apesar das diferenças entre os estudos em relação à causa do delirium. Conclusões Os estudos atuais apontam para uma clara associação entre delirium e aumento do risco de demência. Dessa forma, psiquiatras e médicos generalistas precisam ficar atentos aos indícios de declínio cognitivo após a ocorrência do delirium em idosos.


ABSTRACT Objective To perform an update review of the studies that evaluated delirium as a risk factor for developing dementia in older adults. Methods A review was performed using PubMed database, crossing the following descriptors: risk factors and (delirium or acute confusional state) and dementia. Only cohort studies published from January 2000 to May 2015 were considered. Results We selected eight studies according to the inclusion and exclusion criteria. All studies pointed to an increased risk of dementia or cognitive decline after the occurrence of delirium, despite the differences between the studies in relation to the cause of delirium. Conclusions Recent studies indicate a clear association between delirium and increased risk of dementia. Therefore, the psychiatrists and general practitioners need to pay attention to the evidence of cognitive decline after the occurrence of delirium in older adults.

15.
Psychiatry Res ; 229(3): 739-42, 2015 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-26275706

RESUMO

This study evaluated sensitivity/specificity of self-report instruments for the screening of psychiatric disorders/symptoms in cancer outpatients like: current/past major depression, dysthymia, alcohol abuse and dependence, tobacco abuse and dependence, panic disorder, social anxiety disorder, generalized anxiety disorder, obsessive compulsive disorder, posttraumatic stress disorder, phobias, current mania, delusion and hallucination. First, 1384 patients responded to several self-assessment instruments. Then, 400 patients, were then interviewed by telephone to confirm the presence/absence of psychiatric diagnosis. The ROC analyses showed moderate/excellent specificity (Patient Health Questionnaire-4 (PHQ-4)=0.75-0.88, Generalized Anxiety Disorder (GAD-7)=0.77, Fast Alcohol Screening Test (FAST)=0.83-0.86, Fagerström Test for Nicotine Dependence (FTND)=0.72, Brief version of the Patient Health Questionnaire-Panic Disorder Module (Brief-PD)=0.75, and Self Reporting Questionnaire - psychosis items=(0.68-0.91) but low sensitivity (PHQ-4=0.53-0.54, GAD-7=0.52, FAST=0.48-0.58, FTND=0.97, and Brief-PD=0.66)). These results suggest that sensitivity indicators should be used with caution in the cancer clinical setting.


Assuntos
Transtornos Mentais/diagnóstico , Neoplasias/psicologia , Autoavaliação , Inquéritos e Questionários , Adulto , Feminino , Humanos , Masculino , Transtornos Mentais/psicologia , Psicometria , Curva ROC , Sensibilidade e Especificidade
16.
J Psychosom Res ; 78(1): 91-4, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25242741

RESUMO

OBJECTIVE: This study's objective was to promote the transcultural adaptation of the Patient Health Questionnaire-Panic Disorder Module (PHQ-PD) for Brazilian Portuguese and to evaluate the discriminative validity of this scale in detecting PD among cancer patients. METHODS: Adult cancer outpatients (n=400) from a specialized cancer hospital (61.50% female; 68.40% married; 56% incomplete elementary education or elementary school as the highest educational level) were assessed with the Structured Clinical Interview for DSM-IV and PHQ-PD. Using receiver operating characteristic (ROC) analyses, we determined the sensitivity and specificity values for the original PD algorithm and the PD screening. RESULTS: The prevalence of PD in cancer patients (8.75%) was higher than the prevalence of PD for the general population. The original PD algorithm demonstrated an accuracy of 0.66, sensitivity of 0.31 and specificity of 0.94. The PD screening question in the PHQ-PD had a sensitivity of 0.66 and a specificity of 0.75 (accuracy=0.80). CONCLUSION: PD screening questions in the PHQ-PD may be useful for identifying cancer patients with PD because of the high prevalence of PD in this population and because the questionnaire's sensitivity is greater than that of the original PD algorithm. Nevertheless, researchers and clinical practitioners should consider the original PD algorithm (five items) in the PHQ-PD when they investigate PD in patients because of the algorithm's high specificity. Individuals who are found to be positive for PD on screening should be referred for assessment and a thorough psychiatric interview that focuses on the differential diagnosis of an anxiety disorder relating to cancer.


Assuntos
Programas de Rastreamento/métodos , Neoplasias/psicologia , Transtorno de Pânico/diagnóstico , Transtorno de Pânico/etiologia , Inquéritos e Questionários/normas , Adulto , Idoso , Algoritmos , Brasil , Institutos de Câncer , Manual Diagnóstico e Estatístico de Transtornos Mentais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Curva ROC , Sensibilidade e Especificidade
17.
Psychiatry Res ; 220(1-2): 125-8, 2014 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-25190346

RESUMO

The neuropeptide oxytocin improves the performance in facial emotion recognition tests in healthy volunteers and in individuals with schizophrenia. Different paradigms are used in emotion recognition tasks, engaging different neurobiological bases. To date, the effects of oxytocin in facial emotion matching tasks have not been studied. The objective of this study was to evaluate the effects of intranasal oxytocin in a facial emotion matching task in patients with schizophrenia and healthy volunteers. Twenty patients and 20 healthy volunteers received 48 IU intranasal oxytocin and placebo in a double-blind, randomized, placebo-controlled, within subjects design. Fifty minutes after treatment, subjects completed a facial emotion matching task and three control tests. Oxytocin failed to improve facial affect processing, in contrast with previous results. Possible explanations are the fact that we used a facial emotion matching paradigm instead of emotion labeling tasks and a higher dose of oxytocin than the one used in most similar studies.


Assuntos
Emoções/fisiologia , Expressão Facial , Neuropeptídeos/farmacologia , Ocitocina/farmacologia , Esquizofrenia/tratamento farmacológico , Percepção Social , Adulto , Método Duplo-Cego , Voluntários Saudáveis , Humanos , Masculino , Neuropeptídeos/administração & dosagem , Ocitocina/administração & dosagem , Resultado do Tratamento
18.
J Psychopharmacol ; 28(11): 1088-98, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25237116

RESUMO

INTRODUCTION: Parkinson's disease (PD) has a progressive course and is characterized by the degeneration of dopaminergic neurons. Although no neuroprotective treatments for PD have been found to date, the endocannabinoid system has emerged as a promising target. METHODS: From a sample of 119 patients consecutively evaluated in a specialized movement disorders outpatient clinic, we selected 21 PD patients without dementia or comorbid psychiatric conditions. Participants were assigned to three groups of seven subjects each who were treated with placebo, cannabidiol (CBD) 75 mg/day or CBD 300 mg/day. One week before the trial and in the last week of treatment participants were assessed in respect to (i) motor and general symptoms score (UPDRS); (ii) well-being and quality of life (PDQ-39); and (iii) possible neuroprotective effects (BDNF and H(1)-MRS). RESULTS: We found no statistically significant differences in UPDRS scores, plasma BDNF levels or H(1)-MRS measures. However, the groups treated with placebo and CBD 300 mg/day had significantly different mean total scores in the PDQ-39 (p = 0.05). CONCLUSIONS: Our findings point to a possible effect of CBD in improving quality of life measures in PD patients with no psychiatric comorbidities; however, studies with larger samples and specific objectives are required before definitive conclusions can be drawn.


Assuntos
Canabidiol/uso terapêutico , Fármacos Neuroprotetores/uso terapêutico , Doença de Parkinson/tratamento farmacológico , Idoso , Idoso de 80 Anos ou mais , Ácido Aspártico/análogos & derivados , Ácido Aspártico/metabolismo , Fator Neurotrófico Derivado do Encéfalo/sangue , Creatina/metabolismo , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fármacos Neuroprotetores/sangue , Espectroscopia de Prótons por Ressonância Magnética , Putamen/metabolismo , Qualidade de Vida , Índice de Gravidade de Doença , Resultado do Tratamento
19.
Arq Neuropsiquiatr ; 72(6): 426-9, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24964108

RESUMO

OBJECTIVE: To test the hypothesis that severity of cognitive impairment modifies the association between depression and Parkinson's disease (PD). METHOD: One-phase population-based door-to-door surveys. This is a secondary analysis of 1,451 people aged 65 years and older with cognitive impairment living in defined catchment areas. Depression was estimated according to ICD-10, self-reported PD, disability according to WHODAS-II and cognitive status according to the CSI-D. RESULTS: The mean age of the sample was 79.3 years old and most (69%) were women. Of the total sample, 16.1% had depression and it was significantly higher among participants with PD. There was an increase on the ORs of the association between depression and PD with decreased scores in the cognitive test (Adjusted OR from 0.98 to 8.04). CONCLUSION: The association between depression and PD increases with the severity of the cognitive impairment.


Assuntos
Transtornos Cognitivos/psicologia , Transtorno Depressivo/etiologia , Doença de Parkinson/psicologia , Idoso de 80 Anos ou mais , Transtornos Cognitivos/fisiopatologia , Transtorno Depressivo/fisiopatologia , Escolaridade , Feminino , Humanos , Modelos Logísticos , Masculino , Testes Neuropsicológicos , Doença de Parkinson/fisiopatologia , Índice de Gravidade de Doença
20.
Arq. neuropsiquiatr ; 72(6): 426-429, 06/2014. tab
Artigo em Inglês | LILACS | ID: lil-712675

RESUMO

Objective : To test the hypothesis that severity of cognitive impairment modifies the association between depression and Parkinson’s disease (PD). Method : One-phase population-based door-to-door surveys. This is a secondary analysis of 1,451 people aged 65 years and older with cognitive impairment living in defined catchment areas. Depression was estimated according to ICD-10, self-reported PD, disability according to WHODAS-II and cognitive status according to the CSI-D. Results : The mean age of the sample was 79.3 years old and most (69%) were women. Of the total sample, 16.1% had depression and it was significantly higher among participants with PD. There was an increase on the ORs of the association between depression and PD with decreased scores in the cognitive test (Adjusted OR from 0.98 to 8.04). Conclusion : The association between depression and PD increases with the severity of the cognitive impairment. .


Objetivo : Testar a hipótese que a gravidade do prejuízo cognitivo modifica a associação entre depressão e doença de Parkinson (DP). Método : Estudo populacional através da análise secundária de 1.451 pessoas com idade maior ou igual a 65 anos com prejuízo cognitivo que residiam em áreas de abrangência definidas. A depressão foi estimada de acordo com a CID-10, auto-relato de DP, incapacidade conforme a WHODAS-II e nível cognitvo de acordo com a CSI-D. Resultado : A média de idade foi 79,3 anos, predominaram as mulheres (69%). Do total de indivíduos, 16,1% tinham depressão, significantemente maior entre os participantes com DP. Houve aumento gradativo na OR relativa à associação entre depressão e DP com a diminuição do escore no teste cognitivo (OR ajustado variou de 0,98 a 8,04). Conclusão : A associação entre depressão e DP parece aumentar com a gravidade do prejuízo cognitivo. .


Assuntos
Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Transtornos Cognitivos/psicologia , Transtorno Depressivo/etiologia , Doença de Parkinson/psicologia , Transtornos Cognitivos/fisiopatologia , Transtorno Depressivo/fisiopatologia , Escolaridade , Modelos Logísticos , Testes Neuropsicológicos , Doença de Parkinson/fisiopatologia , Índice de Gravidade de Doença
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