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1.
Talanta ; 207: 120291, 2020 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-31594579

RESUMO

Herein, a simple and green "ON-OFF-ON" sensing system was developed using ultrasonic-exfoliated g-C3N4 nanosheets (CNNS) for the determination of a thiol-based ionic liquid (THIL), which was prominently different from common organic or biothiol molecules in terms of physico-chemical properties. After addition of THIL ([HSBMIM]Br used as an example), the Ag+-quenched CNNS fluorescence ("OFF" state) was recovered to the "ON" state due to reaction between THIL and Ag+ that led to functional group activation on CNNS surfaces. This phenomenon can be explained by competition of THIL with Ag+ because of the strong and specific affinity of -SH groups in THIL for Ag+ and by the reversibility of the Ag+-CNNS coordination reaction. Relevant factors influencing fluorescent recovery were rigorously optimized, including solution pH, incubation time as well as CNNS and THIL concentrations. THIL-recovered fluorescence intensities increased with increasing THIL concentrations providing a linear range of 15-360 nM and limit of detection (LOD) of 4.28 nM (1.07 µg L-1). Testing a series of conventional imidazole-based ionic liquids indicated high specificity for the target analyte and negligible interference effects for the determination of nM-level THIL. The proposed fluorescent sensing method demonstrated excellent feasibility for trace THIL determination in real-world fresh and marine water matrices with high extraction recovery (90.3-107.9%) and high inter- and intra-day precisions (2.3-5.6% relative standard deviations). As far as our information goes, it is the first report on the development of g-C3N4-based "ON-OFF-ON" sensing platform for fast, sensitive and cost-effective determination of nM-level ionic liquids in natural waters.

2.
Biomaterials ; 227: 119552, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31670079

RESUMO

Bone healing is a complex physiological process initiated by early regulation of the inflammatory immunity and entails multiple events including angiogenesis, osteogenic differentiation, and biomineralization. Here, we fabricated an injectable periosteal extracellular matrix (PEM) hydrogel that dynamically integrates multiple biological functions and, therefore, acts at different stages of the fracture healing process. PEM hydrogels were fully characterized compared with a collagen I hydrogel. The effects of PEM hydrogels on the different phases of the healing process were assessed in vitro. PEM hydrogels induced the recruitment and M2-polarization of macrophages, promoted the differentiation of MSCs into endothelial-like cells, HUVEC tube formation, osteogenic differentiation of primary calvarial osteoblasts and MSCs, and mineralization after being immersed in simulated body fluid. The dynamic and multiphase effects of the hydrogels were evaluated using a rat critical-sized calvarial defect model in vivo. During the early phase of repair, PEM hydrogels facilitated the M1-to-M2 transition of macrophages. As bone repair progressed, PEM hydrogels promoted blood vessel migration, the development of relative larger blood vessels, and functional vascularization. These effects were also verified in a subcutaneous embedding model. Eventually, PEM hydrogels promoted mature bone formation in large bone defects to a greater extent than collagen I hydrogels. These biological effects coordinated well with the natural process of bone regeneration. Thus, PEM hydrogels may serve as promising biomaterials in bone tissue engineering.

3.
Neuroimaging Clin N Am ; 30(1): 15-23, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31759568

RESUMO

Resting state functional connectivity (RSFC) has been widely studied in functional magnetic resonance imaging (fMRI) and is observed by a significant temporal correlation of spontaneous low-frequency signal fluctuations (SLFs) both within and across hemispheres during rest. Different hypotheses of RSFC include the biophysical origin hypothesis and cognitive origin hypothesis, which show that the role of SLFs and RSFC is still not completely understood. Furthermore, RSFC and age studies have shown an "age-related compensation" phenomenon. RSFC data analysis methods include time domain analysis, seed-based correlation, regional homogeneity, and principal and independent component analyses. Despite advances in RSFC, the authors also discuss challenges and limitations, ranging from head motion to methodological limitations.

4.
Medicine (Baltimore) ; 98(44): e17850, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31689876

RESUMO

BACKGROUND: Lateral humeral condyle fractures are the second most common elbow fracture in children. Displaced and rotated fractures require stabilization and reduction. Kirschner wires (K-wires) are most commonly used in the fixation of these fractures. Here, we introduce a new fixation method that uses an absorbable screw. We aim to determine if it is feasible to treat lateral humeral condyle fractures with an absorbable screw by comparing functional outcomes following absorbable screw fixation vs. K-wire fixation. METHODS: Between May 2007 and September 2010, 86 patients were treated with absorbable screws (43 patients) or K-wire (43 patients). All patients had been diagnosed with lateral condyle fractures that were classified as either Jacob type II (unstable) or III. One absorbable screw (3.5 mm-diameter) was used for fixation in 1 group, while two 1.6 to 1.8 mm K-wires were used in the other group. Patients were followed 6 months about the elbow function according to Broberg and Morrey standard. On 5-7 years, the patients were followed about the carrying angle (valgus deformities and varus deformities), range of motion (flexion loss and extension loss), prominent lateral condyle, symptomatic implants, and fishtail deformity. RESULTS: Anatomic reduction was achieved in all patients. Each group had one radial nerve injury that were present preoperatively. Nerve function recovered spontaneously within 3 to 4 weeks of surgery in both patients. No patient developed necrosis of the capitulum in both groups. Nine patients in K-wires group and 2 in absorbable screw group developed symptomatic implants (P = .048). On the sixth month, there was no significant difference on elbow function according to Broberg and Morrey standard. On 5 to 7 years (average, 6.7 ±â€Š1.3 years), valgus deformities was 6.8 ±â€Š1.2 vs 5.7 ±â€Š0.8, varus deformities was 7.2 ±â€Š1.5 vs 5.1 ±â€Š1.9, flexion loss was 12.4 ±â€Š2.2 vs 9.5 ±â€Š3.1, extension loss was 11.1 ±â€Š3.1 vs 10.2 ±â€Š2.7, prominent lateral condyle was 27.9% vs 37.2%, fishtail deformity was 7.3% vs 4.9%, no significant difference between these groups. CONCLUSIONS: Open reduction with absorbable screw fixation is feasible and safe for the treatment of lateral condyle fractures of the humerus in children. LEVEL OF EVIDENCE: Therapeutic III.


Assuntos
Implantes Absorvíveis , Parafusos Ósseos , Fixação Interna de Fraturas/métodos , Fraturas do Úmero/cirurgia , Redução Aberta , Suturas , Adolescente , Fios Ortopédicos , Criança , Feminino , Seguimentos , Fixação Interna de Fraturas/efeitos adversos , Fixação Interna de Fraturas/instrumentação , Humanos , Fraturas do Úmero/classificação , Fraturas do Úmero/fisiopatologia , Masculino , Complicações Pós-Operatórias , Amplitude de Movimento Articular , Estudos Retrospectivos
5.
Int J Clin Pharm ; 2019 Nov 07.
Artigo em Inglês | MEDLINE | ID: mdl-31696422

RESUMO

Background The participation of clinical pharmacists in the treatment of acute pancreatitis has rarely been reported. Objective The aim of this study was to retrospectively evaluate the impact of intervention of clinical pharmacists on the treatment of acute pancreatitis. Setting An academic teaching hospital in Taizhou, Jiangsu, China. Method Two hundred and twenty-eight patients with acute pancreatitis were retrospectively enrolled from July 2017 to July 2018 and divided into an intervention group (n = 119) and a control group (n = 109) according to whether a clinical pharmacist was involved. No significant differences in the baseline clinical characteristics were found between the groups. Clinical pharmacists participated in drug formulation and adjustment, pharmaceutical care, and follow-up. Main outcome measure Clinical outcomes, average hospital stays, costs, incidence of adverse drug reactions, 1-month subsequent visit rate, and patient satisfaction between the two groups were measured. Results The clinical symptoms of patients in both groups were relieved after treatment. There were no significant differences between the groups in computed tomography grades after treatment, incidence of adverse drug reactions, or average hospital stays. However, the intervention group had lower total costs of hospitalization, drugs and antibiotics but higher rates of 1-month subsequent visits and satisfaction compared with the control group. Conclusion The intervention of clinical pharmacists in the treatment of acute pancreatitis can effectively reduce costs of hospitalization, drug and antibiotics and improve follow-up compliance and patient satisfaction.

6.
Neuropsychol Rehabil ; : 1-20, 2019 Nov 07.
Artigo em Inglês | MEDLINE | ID: mdl-31696782

RESUMO

This study aims to evaluate the relationship between traumatic brain injury (TBI) and sleep disorders (SDs). We first initiated a questionnaire-based clinical survey to assess sleep problems in the early stage after a TBI, followed by a population-based cohort study to evaluate the long-term risk of SDs in TBI patients. For short-term clinical survey, mild (m)TBI patients and healthy controls were recruited to evaluate the sleep quality and daytime sleepiness using the Pittsburg Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) within two weeks after a TBI. For long-term observation, a 5-year nationwide population-based cohort study that utilized a large administrative database was conducted. In the short-term survey, 236 mTBI patients and 223 controls were analyzed. Total scores of the PSQI and ESS were significantly higher in mTBI patients than in the controls. In the long-term cohort study, 6932 TBI cases and 34,660 matched controls were included. TBI cases had a 1.36-fold greater risk of SDs compared to the non-TBI controls during the 5-year follow-up period. Results showed that patients with TBI had a significantly higher risk of SDs than did controls both in the early stage and during a 5-year follow-up period.

7.
Theranostics ; 9(25): 7849-7871, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31695804

RESUMO

With further research into the molecular mechanisms and roles linking immune suppression and restraint of (pre)malignancies, immunotherapies have revolutionized clinical strategies in the treatment of cancer. However, nearly 70% of patients who received immune checkpoint therapeutics showed no response. Complementary and/or synergistic effects may occur when extracellular checkpoint antibody blockades combine with small molecules targeting intracellular signal pathways up/downstream of immune checkpoints or regulating the innate and adaptive immune response. After radiolabeling with radionuclides, small molecules can also be used for estimating treatment efficacy of immune checkpoint blockades. This review not only highlights some significant intracellular pathways and immune-related targets such as the kynurenine pathway, purinergic signaling, the kinase signaling axis, chemokines, etc., but also summarizes some attractive and potentially immunosuppression-related small molecule agents, which may be synergistic with extracellular immune checkpoint blockade. In addition, opportunities for small molecule-based theranostics in cancer immunology will be discussed.

8.
Artigo em Inglês | MEDLINE | ID: mdl-31755200

RESUMO

Heterostructural metal/metal oxides are the very promising substituents of noble-metal catalysts; however, generation and further stabilization of accessible metal/metal oxide heterojunctions are very difficult. Herein, a strategy to in situ encapsulate and stabilize Cu/Cu-2O nanojunctions in porous organic frameworks is developed by tuning the acrylate contents in copper-based metal-organic frameworks (Cu-MOFs) and the pyrolytic conditions. The acrylate groups play important roles on improving the polymerization degree of organic frameworks, and generating and stabilizing highly dispersed and accessible Cu/Cu2O heteronanojunctions. As a result, pyrolysis of the MOF ZJU-199, consisting of three acrylates per ligand, generates abundant heterostructural Cu/Cu2O discrete domains inside porous organic matrices at 350 oC, demonstrating excellent catalytic properties in liquid-phase hydrogenation of furfural into furfuryl alcohol, which are much superior to the non-noble metal-based catalysts in the literature. This work provides a promising pathway for developing highly efficient non-noble metal catalysts in practical applications.

9.
Int J Biol Macromol ; 2019 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-31739027

RESUMO

Facile preparation of super tough hydrogels with low temperature tolerance and anti-swelling property is still a challenging task for researchers. Meanwhile, the vast majority of tough hydrogels were obtained though chemical crosslinking and complicated synthesis or processing method accompanying a large number of harmful chemical reagents. Herein, the super tough chitosan/poly(vinyl alcohol) (CS/PVA) hydrogels (the maximum compressive strength of 18.97 MPa at a strain of 80% and the maximum tensile strength of 4.02 MPa at a strain of 406.4%) were successfully prepared via a simple post-treatment method. CS/PVA hydrogels were firstly prepared by freezing-thawing process and then soaking in saturated sodium chloride aqueous solution. The resultant hydrogels possess excellent swelling resistance and low temperature tolerance. This work shows that the post-treatment of immersing in saline solution is a feasible way to prepare super tough hydrogels with low temperature tolerance and anti-swelling property. This also would enlarge the application areas of CS.

10.
Phys Chem Chem Phys ; 21(44): 24695-24701, 2019 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-31674632

RESUMO

In recent years, another two-dimensional (2D) family, monolayer metal monochalcogenides (group IIIA-VIA), has attracted extensive attention. In this work, we adopt density functional theory (DFT) and the non-equilibrium Green's function (NEGF) method to systematically investigate the ballistic thermoelectric properties of the IIIA-VIA family, including GaS, GaSe, GaTe, InS, InSe, and InTe. Among others, the InTe monolayer possesses the highest figure of merit, ZT = 2.03 at 300 K, due to its ultra-low thermal conductance. Biaxial strain in the range of -10% (compressive) to 10% (tensile) is applied to the InTe monolayer and the strain-induced electronic and thermal transport properties are discussed. The maximum ZT (up to 2.7) for the InTe monolayer at 300 K is achieved under an 8% tensile strain.

11.
Adv Mater ; : e1905679, 2019 Nov 18.
Artigo em Inglês | MEDLINE | ID: mdl-31736168

RESUMO

To meet the practical demand of overall water splitting and regenerative metal-air batteries, highly efficient, low-cost, and durable electrocatalysts for the oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evolution reaction (HER) are required to displace noble metal catalysts. In this work, a facile solid-state synthesis strategy is developed to construct the interfacial engineering of W2 N/WC heterostructures, in which abundant interfaces are formed. Under high temperature (800 °C), volatile CNx species from dicyanodiamide are trapped by WO3 nanorods, followed by simultaneous nitridation and carbonization, to form W2 N/WC heterostructure catalysts. The resultant W2 N/WC heterostructure catalysts exhibit an efficient and stable electrocatalytic performance toward the ORR, OER, and HER, including a half-wave potential of 0.81 V (ORR) and a low overpotential at 10 mA cm-2 for the OER (320 mV) and HER (148.5 mV). Furthermore, a W2 N/WC-based Zn-air battery shows outstanding high power density (172 mW cm-2 ). Density functional theory and X-ray absorption fine structure analysis computations reveal that W2 N/WC interfaces synergistically facilitate transport and separation of charge, thus accelerating the electrochemical ORR, OER, and HER. This work paves a novel avenue for constructing efficient and low-cost electrocatalysts for electrochemical energy devices.

12.
Nat Commun ; 10(1): 5230, 2019 Nov 19.
Artigo em Inglês | MEDLINE | ID: mdl-31745089

RESUMO

The Hengduan Mountains (HDM) biodiversity hotspot exhibits exceptional alpine plant diversity. Here, we investigate factors driving intraspecific divergence within a HDM alpine species Salix brachista (Cushion willow), a common component of subnival assemblages. We produce a high-quality genome assembly for this species and characterize its genetic diversity, population structure and pattern of evolution by resequencing individuals collected across its distribution. We detect population divergence that has been shaped by a landscape of isolated sky island-like habitats displaying strong environmental heterogeneity across elevational gradients, combined with population size fluctuations that have occurred since approximately the late Miocene. These factors are likely important drivers of intraspecific divergence within Cushion willow and possibly other alpine plants with a similar distribution. Since intraspecific divergence is often the first step toward speciation, the same factors can be important contributors to the high alpine species diversity in the HDM.

13.
ChemSusChem ; 2019 Oct 31.
Artigo em Inglês | MEDLINE | ID: mdl-31671246

RESUMO

A visible-light-promoted metal-free carboxylative cyclization of propargylic amines with CO2 was shown to offer exo-iodomethylene 2-oxazolidinones. Incorporation of both CO2 and iodo moieties into these compounds was realized efficiently. The mechanism study revealed that this carboxylative cyclization proceeds through a radical pathway. Notably, the iodine-functionalized 2-oxazolidinone as a platform molecule could be easily converted into a wide range of value-added chemicals through Buchwald-Hartwig, Suzuki, Sonogashira, photocatalytic ene, and photoreduction reactions. As a result, the plentiful downstream transformations remarkably enhance the range of chemicals derived from CO2 and open a potential avenue for CO2 functionalization to circumvent energy challenges in this field.

14.
Artigo em Inglês | MEDLINE | ID: mdl-31746192

RESUMO

As a new two-dimensional material similar to graphene, Mxene has attracted extensive attention in the field of electrochemical materials such as supercapacitors because of its excellent mechanical properties, conductivity, and thermal conductivity. What's better than graphene is that the few layers Mxene material obtained by proper treatment has good water dispersibility and can be used as an ideal nano-material to enhance the conductivity of hydrogels. While the articles about the few layers Mxene material used in the preparation of composite hydrogels are rare. In this paper, Mxene was synthesized by Yury mild method. PNIPAM hydrogel and physical crosslinking hydrogel were used as the matrix to prepare composite hydrogels with temperature sensitivity and stress sensing properties. The composite hydrogels exhibited excellent mechanical properties, it could be stretched to over 14 times the original length, and reached 0.4 MPa tensile strength, while showing good self-healing ability, which was of great significance for the practical application of hydrogels. The conductivity of the composite hydrogel was 1.092 S/m, which was about 15 times that of the control hydrogel without Mxene. The potential of the composite hydrogel as a smart compression sensor was also verified by the conductivity tests.

15.
World Neurosurg ; 2019 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-31678438

RESUMO

OBJECTIVES: The present study introduced electronic conductivity device (ECD) to reduce time of percutaneous transpedicular puncture and frequency of patient valid radiation exposure in percutaneous kyphoplasty (PKP) or percutaneous vertebroplasty (PVP). METHODS: A randomized self-control clinical study was undertaken. Medical records of patients with vertebral compression fractures (VCFs) for bilateral PKP or PVP were collected, and each side was performed randomly with ECD or conventional trocar. RESULTS: We enrolled 61 patients (44 women, 17 men) with 75 vertebras with VCF. Compared with the conventional fluoroscopy group, significant reductions in puncture time (504.33±152.03 vs. 652.68±167.60 s; P < 0.001) and fluoroscopy frequency (5.11±1.23 vs. 8.15±1.83; P < 0.001) for each percutaneous puncture were observed in the ECD group. When compared with VCFs ≤ 50% group, the two indexes in VCFs>50% group were significantly increased. And in ECD group, the learning curve in VCFs>50% group showed a steeper decreasing trend than that in VCFs ≤ 50% group. No complications were observed in any patient. CONCLUSIONS: ECD could obviously reduce puncture time of percutaneous transpedicular puncture and exposure of radiation in PVP and PKP. ECD has more benefits in complicated transpedicular puncture in patients with vertebral compression >50%.

16.
Eur Heart J ; 40(41): 3440-3441, 2019 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-31674650
17.
Gut ; 2019 Nov 14.
Artigo em Inglês | MEDLINE | ID: mdl-31727683

RESUMO

OBJECTIVE: Autophagy participates in the progression of hepatocellular carcinoma (HCC) and the resistance of HCC cells to sorafenib. We investigated the feasibility of sensitising HCC cells to sorafenib by modulating miR-541-initiated microRNA-autophagy axis. DESIGN: Gain- and loss-of-function assays were performed to evaluate the effects of miR-541 on the malignant properties and autophagy of human HCC cells. Autophagy was quantified by western blotting of LC3, transmission electron microscopy analyses and confocal microscopy scanning of mRFP-GFP-LC3 reporter construct. Luciferase reporter assays were conducted to confirm the targets of miR-541. HCC xenograft tumours were established to analyse the role of miR-541 in sorafenib-induced lethality. RESULTS: The expression of miR-541 was downregulated in human HCC tissues and was associated with malignant clinicopathologic phenotypes, recurrence and survival of patients with HCC. miR-541 inhibited the growth, metastasis and autophagy of HCC cells both in vitro and in vivo. Prediction software and luciferase reporter assays identified autophagy-related gene 2A (ATG2A) and Ras-related protein Rab-1B (RAB1B) as the direct targets of miR-541. Consistent with the effects of the miR-541 mimic, inhibition of ATG2A or RAB1B suppressed the malignant phenotypes and autophagy of HCC cells. Furthermore, siATG2A and siRAB1B partially reversed the enhancement of the malignant properties and autophagy in HCC cells mediated by the miR-541 inhibitor. More interestingly, higher miR-541 expression predicted a better response to sorafenib treatment, and the combination of miR-541 and sorafenib further suppressed the growth of HCC cells in vivo compared with the single treatment. CONCLUSIONS: Dysregulation of miR-541-ATG2A/RAB1B axis plays a critical role in patients' responses to sorafenib treatment. Manipulation of this axis might benefit survival of patients with HCC, especially in the context of the highly pursued strategies to eliminate drug resistance.

18.
Autism Res ; 2019 Nov 14.
Artigo em Inglês | MEDLINE | ID: mdl-31729198

RESUMO

As one of the key regions in the "social brain" network, the middle temporal gyrus (MTG) has been widely reported to be associated with autism spectrum disorder (ASD), but there have been contradictory results in terms of whether it shows hyperconnectivity or hypoconnectivity. Delineating roles of MTG at the subregional level may eliminate the observed inconsistencies and provide a new avenue to reveal the neurophysiologic mechanism of ASD. Thus, we first performed connectivity-based parcellation using the BrainMap database to identify fine-grained functional topography of the MTG. Then, the MTG subregions were used to investigate differences in the functional connectivity in children and adults with ASD using two data sets from Autism Brain Imaging Data Exchange database. Four distinct subregions in the human left and right MTG were identified, including the anterior MTG (aMTG), middle-anterior MTG (maMTG), middle-posterior MTG, and posterior MTG (pMTG). The bilateral pMTG was more vulnerable in both children and adults with ASD than in the typically developing (TD) group, mainly showing hypoconnectivity with different brain regions. In addition, the bilateral aMTG and right maMTG also showed altered functional connectivity in adults with ASD compared to the TD group. Moreover, all these altered MTG subregions were mainly associated with social cognition and language, as revealed by functional characterization. Further correlation analyses also showed trends of association between altered connectivity of the left aMTG and the Autism Diagnostic Observation Schedule scores in adults with ASD. Together, these results suggest a potential objective way to explore sub-regional differences associated with such disorders. Autism Res 2019. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Four distinct subregions in the human left and right middle temporal gyrus (MTG) were identified, including the anterior MTG (aMTG), middle-anterior MTG (maMTG), middle-posterior MTG, and posterior MTG (pMTG). The bilateral pMTG was more vulnerable in both children and adults with autism spectrum disorder (ASD) than in the typically developing (TD) group, mainly showing hypoconnectivity with different brain regions. In addition, the bilateral aMTG and right maMTG also showed altered functional connectivity in adults with ASD compared to the TD group. Moreover, all these altered MTG subregions were mainly associated with social cognition and language, as revealed by functional characterization. Further correlation analyses also showed trends of association between altered connectivity of the left aMTG and the Autism Diagnostic Observation Schedule scores in adults with ASD.

19.
Nanoscale ; 11(45): 22033-22041, 2019 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-31714554

RESUMO

Strong couplings between molecular excitons and metal plasmons bring advantages to effectively manipulate the optical properties of hybrid systems, including both absorption and fluorescence. In contrast to absorption behaviours, which have been quite well understood and can be categorized into different regimes such as Fano dip and Rabi splitting, the characteristics of fluorescence in strongly coupled hybrids remain largely unexplored. Quenching instead of the enhancement of fluorescence is usually observed in the corresponding experiments, and a theoretical model to deal with this phenomenon is still lacking. Herein, we demonstrate a largely enhanced fluorescence in a hybrid system with Cy5 dye molecules strongly coupled to Ag nanoparticle films, signified by the huge Rabi splitting absorption spectra. The plexciton Rabi splitting of the hybrids can be tuned from 320 meV to as large as 750 meV by adjusting both plasmon strength and molecular concentration. Moreover, when the excitation and emission wavelengths are respectively tuned to be resonant with the two Rabi peaks, the hybrid acting as a plexcitonic dual resonant antenna exhibits an enhanced fluorescence 44 times larger than that of the free dye molecule. We also develop a theoretical model to simultaneously study the characteristics of both the absorption and emission spectra, including the peak shifting and strength. These findings offer a new strategy to design and fabricate plexcitonic devices with tunable optical responses and efficient fluorescence.

20.
Dtsch Arztebl Int ; 116(43): 736, 2019 Oct 25.
Artigo em Inglês | MEDLINE | ID: mdl-31755410
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