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1.
Nat Biomed Eng ; 2020 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-32632226

RESUMO

Patients with kidney failure commonly require dialysis to remove nitrogenous wastes and to reduce burden to the kidney. Here, we show that a bacterial cocktail orally delivered in animals with kidney injury can metabolize blood nitrogenous waste products before they diffuse through the intestinal mucosal barrier. The microbial cocktail consists of three strains of bacteria isolated from faecal microbiota that metabolize urea and creatinine into amino acids, and is encapsulated in calcium alginate microspheres coated with a polydopamine layer that is selectively permeable to small-molecule nitrogenous wastes. In murine models of acute kidney injury and chronic kidney failure, and in porcine kidney failure models, the encapsulated microbial cocktail significantly reduced urea and creatinine concentrations in blood, and did not lead to any adverse effects.

2.
J Org Chem ; 2020 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-32666792

RESUMO

A catalytic asymmetric synthesis of 3,3'-bisindoles bearing single axial chirality has been established via chiral phosphoric acid (CPA) catalyzed enantioselective addition reaction of 3,3'-bisindoles with ninhydrin-derived 3-indolylmethanols. The selection of ninhydrin-derived 3-indolylmethanols as suitable electrophiles is based on the consideration that the symmetric and bulky moiety of ninhydrin would increase the steric congestion around the axis to generate stable axial chirality and avoid the generation of central chirality. By this approach, a series of 3,3'-bisindoles bearing single axial chirality were synthesized via dynamic kinetic resolution (DKR) process in generally acceptable yields and considerable enantioselectivities. In addition, an in-depth investigation on the property (stability and rotation barrier) of the synthesized axially chiral 3,3'-bisindoles were carried out, thus providing useful information for this class of axially chiral frameworks. This approach makes use of the strategy of dynamic kinetic resolution of 3,3'-bisindoles, therefore expanding the generality and applicability of this strategy for catalytic asymmetric synthesis of 3,3'-bisindoles bearing single axial chirality.

3.
Angew Chem Int Ed Engl ; 58(42): 15104-15110, 2019 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-31441203

RESUMO

A new strategy for enantioselective synthesis of axially chiral naphthyl-indoles has been established through catalytic asymmetric addition reactions of racemic naphthyl-indoles with bulky electrophiles. Under chiral phosphoric acid catalysis, azodicarboxylates and o-hydroxybenzyl alcohols served as bulky but reactive electrophiles that were attacked by C2-unsubstituted naphthyl-indoles, which underwent a dynamic kinetic resolution to afford two series of axially chiral naphthyl-indoles in good yields (up to 98 %) and high enantioselectivities (up to 98:2 er).

4.
Nat Biomed Eng ; 3(9): 717-728, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31332342

RESUMO

The microbiota in the human gut is strongly correlated with the progression of colorectal cancer (CRC) and with therapeutic responses to CRC. Here, by leveraging the higher concentration of the pro-tumoural Fusobacterium nucleatum and the absence of antineoplastic butyrate-producing bacteria in the faecal microbiota of patients with CRC, we show that-in mice with orthotopic colorectal tumours or with spontaneously formed colorectal tumours-oral or intravenous administration of irinotecan-loaded dextran nanoparticles covalently linked to azide-modified phages that inhibit the growth of F. nucleatum significantly augments the efficiency of first-line chemotherapy treatments of CRC. We also show that oral administration of the phage-guided irinotecan-loaded nanoparticles in piglets led to negligible changes in haemocyte counts, immunoglobulin and histamine levels, and liver and renal functions. Phage-guided nanotechnology for the modulation of the gut microbiota might inspire new approaches for the treatment of CRC.


Assuntos
Bactérias/efeitos dos fármacos , Bactérias/virologia , Bacteriófagos , Neoplasias Colorretais/tratamento farmacológico , Neoplasias Colorretais/microbiologia , Tratamento Farmacológico/métodos , Microbioma Gastrointestinal/fisiologia , Animais , Antineoplásicos/uso terapêutico , Bactérias/crescimento & desenvolvimento , Bactérias/metabolismo , Butiratos/metabolismo , Linhagem Celular Tumoral , Proliferação de Células/efeitos dos fármacos , Neoplasias do Colo/tratamento farmacológico , Neoplasias do Colo/microbiologia , Neoplasias Colorretais/patologia , Dextranos , Modelos Animais de Doenças , Fusobacterium nucleatum/efeitos dos fármacos , Fusobacterium nucleatum/crescimento & desenvolvimento , Fusobacterium nucleatum/metabolismo , Fusobacterium nucleatum/virologia , Microbioma Gastrointestinal/efeitos dos fármacos , Imunoglobulinas , Irinotecano/farmacologia , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Nanopartículas
5.
Org Biomol Chem ; 17(16): 3894-3901, 2019 04 17.
Artigo em Inglês | MEDLINE | ID: mdl-30938404

RESUMO

A phosphine-catalyzed regiospecific (3 + 2) cyclization of 3-nitroindoles with allene esters has been established, which constructed indole-fused five-membered rings in good yields (up to 86%). This reaction serves as a powerful method for the construction of indole-fused five-membered rings. In addition, this reaction provides a useful strategy toward settling the challenge of utilizing other 1,3-dipoles or 1,3-dipole surrogates to perform (3 + 2) cyclizations with 3-nitroindoles in different catalytic modes, which will enrich the chemistry of nitroindoles and catalytic asymmetric dearomatization cyclizations.

6.
Org Biomol Chem ; 17(9): 2361-2369, 2019 02 27.
Artigo em Inglês | MEDLINE | ID: mdl-30623950

RESUMO

The first [4 + 2] cyclization of para-quinone methide (p-QM) derivatives with allenes has been established via phosphine catalysis, which afforded a series of chroman derivatives in high yields (up to 97%) and excellent (E/Z)-selectivities (all >95 : 5 E/Z). This reaction will not only enrich the research contents of cyclization reactions involving p-QM derivatives, but also provide a good example of the application of allenes and phosphine catalysis in cyclization reactions. In addition, this approach also offers a useful method for the construction of chroman scaffolds.

7.
J Cell Biochem ; 119(11): 8922-8936, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-29953665

RESUMO

Accumulating evidence suggests that autophagy plays a protective role in chondrocytes and prevents cartilage degeneration in osteoarthritis (OA). The objective of this study was to investigate the effect of diazoxide on chondrocyte death and cartilage degeneration and to determine whether these effects are correlated to autophagy in experimental OA. In this study, a cellular OA model was established by stimulating SW1353 cells with interleukin 1ß. A rat OA model was generated by transecting the anterior cruciate ligament combined with the resection of the medial menisci, followed by treatment with diazoxide or diazoxide combination with 3-methyladenine. The percentage of viable cells was evaluated using calcein-acetoxymethyl/propidium iodide double staining. The messenger RNA expression levels of collagen type II alpha 1 chain (COL2A1), matrix metalloproteinase 13 (MMP-13), TIMP metallopeptidase inhibitor 1 (TIMP-1), and a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5) were determined using quantitative real-time polymerase chain reaction. The cartilage thickness and joint space were evaluated using ultrasound. SW1353 cell degeneration and autophagosomes were observed using transmission electron microscopy. The expression levels of microtubule-associated protein 1 light chain 3 (LC3), beclin-1, P62, COL2A1, and MMP-13 were evaluated using immunofluorescence staining and Western blot analysis. Diazoxide significantly attenuated articular cartilage degeneration and SW1353 cell death in experimental OA. The restoration of autophagy was observed in the diazoxide-treated group. The beneficial effects of diazoxide were markedly blocked by 3-methyladenine. Diazoxide treatment also modulated the expression levels of OA-related biomarkers. These results demonstrated that diazoxide exerted a chondroprotective effect and attenuated cartilage degeneration by restoring autophagy via modulation of OA-related biomarkers in experimental OA. Diazoxide treatment might be a promising therapeutic approach to prevent the development of OA.


Assuntos
Diazóxido/uso terapêutico , Osteoartrite/tratamento farmacológico , Proteína ADAMTS5/metabolismo , Animais , Autofagia/efeitos dos fármacos , Biomarcadores/sangue , Western Blotting , Sobrevivência Celular/efeitos dos fármacos , Condrossarcoma/tratamento farmacológico , Condrossarcoma/metabolismo , Colágeno Tipo II/metabolismo , Humanos , Masculino , Metaloproteinase 13 da Matriz/metabolismo , Microscopia Eletrônica de Transmissão , Osteoartrite/metabolismo , RNA Mensageiro/metabolismo , Ratos
8.
Insect Sci ; 25(2): 337-351, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27604698

RESUMO

The slow growth-high mortality hypothesis (SG-HG) predicts that slower growing herbivores suffer greater mortality due to a prolonged window of vulnerability. Given diverse plant-herbivore-natural enemy systems resulting from different feeding ecologies of herbivores and natural enemies, this hypothesis might not always be applicable to all systems. This is evidenced by mixed support from empirical data. In this study, a meta-analysis of the SG-HM hypothesis for insects was conducted, aiming to find conditions that favor or reject SG-HM. The analysis revealed significant within- and between-group heterogeneity for almost all explanatory variables and overall did not support SG-HM. In this analysis, SG-HM was supported when any of the following 5 conditions was met: (1) host food consisted of artificial diet; (2) herbivore growth was measured as larval mass; (3) herbivores were generalists; (4) no or multiple species of natural enemies were involved in the study; and (5) parasitoids (i.e., parasitic insects) involved in the study were gregarious. SG-HM was rejected when any of the following 5 conditions was met: (1) herbivores were from the order Hymentoptera; (2) parasitoids from more than 1 order caused herbivore mortality; (2) parasitoids were specialists; (3) parasitoids were solitary; (4) parasitoids were idiobionts or koinobionts; and (5) single species of natural enemy caused mortality of specialist herbivores. All known studies investigated herbivore mortality for a short period of their life cycle. Researchers are encouraged to monitor herbivore mortality during the entire window of susceptibility or life cycle using life tables. Studies involving multiple mortality factors (i.e., both biotic and abiotic) or multiple natural enemy species are also encouraged since herbivores in nature face a multitude of risks during the entire life cycle. More comprehensive studies may increase our understanding of factors influencing the relationships between herbivore growth and mortality.


Assuntos
Herbivoria , Insetos/crescimento & desenvolvimento , Mortalidade , Animais , Cadeia Alimentar
9.
Biomed Pharmacother ; 95: 1886-1894, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28968949

RESUMO

Osteoarthritis (OA) is a common disease affecting elderly individuals. Its incidence rises sharply with age, and chondrocyte apoptosis plays a vital role in its pathogenesis. Diazoxide opens mitochondrial ATP-sensitive potassium (mitoKATP) channels and exerts multiple pharmacological effects, including reductions in blood pressure and blood sugar levels. It also exerts anti-apoptotic activities, but the cellular and molecular mechanisms by which diazoxide inhibits chondrocyte apoptosis are unknown, as is whether apoptosis is related to endoplasmic reticulum stress (ERS). In the present study, we explored the mechanism underlying the chondroprotective effect of diazoxide on hydrogen peroxide (H2O2)-stimulated chondrocyte apoptosis in rats with surgically induced OA. A cell counting kit-8 (CCK-8) assay showed that the viability of H2O2-stimulated chondrocytes was enhanced in a dose-dependent manner. However, at a concentration ≥400µM, diazoxide had other, negative effects. The protective effect of diazoxide in vitro included inhibition of the ERS response and of mitochondrial dysfunction induced by H2O2 stimulation. These responses were related to activation of the PERK1/2 and ERK1/2 signaling pathways; the prevention of chondrocyte apoptosis; the down-regulation of caspase-3, Bax, ATF-6 and C/EBP-homologous protein (CHOP) expression; and the up-regulation of Bcl-2 and Col II. In vivo, histological and immunohistochemical analyses of caspase-3 and CHOP expression revealed that diazoxide ameliorated cartilage degeneration in a rat model of OA, as revealed by histological and immunohistochemical analyses of caspase-3 and CHOP expression. Diazoxide suppressed H2O2-triggered chondrocyte apoptosis, and ameliorated cartilage degeneration, by inhibiting the development of ERS.


Assuntos
Artrite Experimental/tratamento farmacológico , Condrócitos/efeitos dos fármacos , Diazóxido/farmacologia , Osteoartrite/tratamento farmacológico , Animais , Apoptose/efeitos dos fármacos , Artrite Experimental/patologia , Cartilagem Articular/efeitos dos fármacos , Cartilagem Articular/patologia , Caspase 3/metabolismo , Condrócitos/patologia , Diazóxido/administração & dosagem , Relação Dose-Resposta a Droga , Estresse do Retículo Endoplasmático/efeitos dos fármacos , Peróxido de Hidrogênio/toxicidade , Masculino , Osteoartrite/patologia , Ratos , Ratos Sprague-Dawley , Transdução de Sinais/efeitos dos fármacos , Fator de Transcrição CHOP/metabolismo
10.
Anal Chem ; 89(8): 4349-4354, 2017 04 18.
Artigo em Inglês | MEDLINE | ID: mdl-28365980

RESUMO

A novel single-molecular fluorescent probe was developed for spatiotemporal matrix metalloproteinase-2 (MMP-2) and caspase-3 imaging with distinct fluorescence signals. Due to the multi-Förster resonance energy transfer (FRET) processes, the probe could respond to MMP-2 and caspase-3 independently with high signal-to-noise ratio. Moreover, the overexpression of MMP-2 in cancer cell lines and the cisplatin induced cell apoptosis were spatiotemporal imaged with distinct fluorescence emissions. Because of the independent process of the probe for MMP-2 and caspase-3 imaging, the probe could meet the demands for precise disease diagnosis and cancer theranostic applications, which could extensively simplify the processes for precise cancer diagnosis and imaging.


Assuntos
Caspase 3/metabolismo , Transferência Ressonante de Energia de Fluorescência , Corantes Fluorescentes/química , Metaloproteinase 2 da Matriz/metabolismo , Animais , Células COS , Caspase 3/química , Linhagem Celular Tumoral , Chlorocebus aethiops , Citometria de Fluxo , Humanos , Metaloproteinase 2 da Matriz/química , Microscopia Confocal
11.
J Obstet Gynaecol Res ; 42(12): 1839-1845, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27647799

RESUMO

AIM: To evaluate the analytical and clinical effectiveness of cervicovaginal self-sampling with a dry sampling device (Evalyn Brush) for high-risk human papillomavirus (hr-HPV) testing and detection of cervical disease. METHODS: The study population consisted of 101 patients from a large gynecological outpatient clinic in Shanghai referred for abnormal cervical screening results and 101 women without cervical lesions. Self-samples obtained in the clinic and physician-collected cervical specimens (reference) were stored at -20 °C for 16-18 weeks and then transferred to 20 ml of ThinPrep medium and tested for hr-HPV using a multiplex real time polymerase chain reaction assay. All women had a colposcopic examination with a Pap smear and directed or random biopsies. RESULTS: High risk-HPV was detected in 92 patients (45.5%) with the self-collected cervicovaginal specimens and in 93 (46.0%) with the physician-collected cervical specimens, resulting in an agreement of 97.5% and a Kappa of 0.95 (95% confidence interval 0.91-0.99). Among all of the included women, 46 (22.8%) had cervical intraepithelial neoplasia grade 3 or worse (cervical intraepithelial neoplasia 3+). Hr-HPV was found in 43 of these patients (93.5%) with self-sampling and in 44 (95.7%) with the physician-collected specimens. CONCLUSIONS: Self-collected dry cervicovaginal samples transferred to ThinPrep medium and tested for hr-HPV using a clinically validated polymerase chain reaction assay showed very good agreement with physician-collected cervical specimens and a very high hr-HPV positivity rate for cervical intraepithelial neoplasia 3 +.


Assuntos
Sondas de DNA de HPV , Detecção Precoce de Câncer/métodos , Infecções por Papillomavirus/diagnóstico , Neoplasias do Colo do Útero/virologia , Adulto , Idoso , China , Feminino , Humanos , Pessoa de Meia-Idade , Papillomaviridae/genética , Infecções por Papillomavirus/genética , População Urbana , Adulto Jovem
12.
Am J Emerg Med ; 33(2): 305.e5-8, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25070194

RESUMO

Spontaneous pneumomediastinum is defined as presence of air in the mediastinum without obvious cause such as esophageal perforation or abscess formation. It is a benign condition and usually resolved by itself in 1 to 2 weeks. The main symptom of spontaneous pneumomediastinum is retrosternal chest pain. Here, we present a young adult who complained about sore throat initially. Marked retropharyngeal emphysema was noted by neck x-ray. Pneumomediastinum was confirmed with chest x-ray and computed tomographic scan later on.We want to emphasize the importance of thorough history taking and lateral soft tissue neck radiograph on retropharyngeal emphysema in real time, which is key to the diagnostic workup for patients who present with persistent sore throat and dysphagia in young adult.


Assuntos
Enfisema Mediastínico/diagnóstico , Faringite/etiologia , Adolescente , Diagnóstico Precoce , Humanos , Masculino , Enfisema Mediastínico/complicações , Enfisema Mediastínico/diagnóstico por imagem , Tomografia Computadorizada por Raios X
13.
Front Comput Neurosci ; 8: 125, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25339895

RESUMO

The Independent Component Analysis (ICA)-linear non-Gaussian acyclic model (LiNGAM), an algorithm that can be used to estimate the causal relationship among non-Gaussian distributed data, has the potential value to detect the effective connectivity of human brain areas. Under the assumptions that (a): the data generating process is linear, (b) there are no unobserved confounders, and (c) data have non-Gaussian distributions, LiNGAM can be used to discover the complete causal structure of data. Previous studies reveal that the algorithm could perform well when the data points being analyzed is relatively long. However, there are too few data points in most neuroimaging recordings, especially functional magnetic resonance imaging (fMRI), to allow the algorithm to converge. Smith's study speculates a method by pooling data points across subjects may be useful to address this issue (Smith et al., 2011). Thus, this study focus on validating Smith's proposal of pooling data points across subjects for the use of LiNGAM, and this method is named as pooling-LiNGAM (pLiNGAM). Using both simulated and real fMRI data, our current study demonstrates the feasibility and efficiency of the pLiNGAM on the effective connectivity estimation.

14.
BMC Surg ; 14: 47, 2014 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-25051994

RESUMO

BACKGROUND: Cancellation of surgery close to scheduled time causes a waste of healthcare resources. The current study analyzes surgery cancellations occurring after the patient has been prepared for the operating room, in order to see whether improvements in the surgery planning process may reduce the number of cancellations. METHODS: In a retrospective chart review of operating room surgery cancellations during the period from 2006 to 2011, cancellations were divided into the following categories: inadequate NPO; medical; surgical; system; airway; incomplete evaluation. The relative use of these reasons in relation to patient age and surgical department was then evaluated. RESULTS: Forty-one percent of cancellations were for other than medical reasons. Among these, 17.7% were due to incomplete evaluation, and 8.2% were due to family issues. Sixty seven percent of cancelled cases eventually received surgery. The relative use of individual reasons for cancellation varied with patient age and surgical department. The difference between cancellations before and after anesthesia was dependent on the causes of cancellation, but not age, sex, ASA status, or follow-up procedures required. CONCLUSION: Almost half of the cancellations were not due to medical reasons, and these cancellations could be reduced by better administrative and surgical planning and better communication with the patient and/or his family.


Assuntos
Agendamento de Consultas , Tomada de Decisões Gerenciais , Neoplasias/cirurgia , Salas Cirúrgicas/organização & administração , Cuidados Pré-Operatórios , Procedimentos Cirúrgicos Operatórios , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto Jovem
15.
J Cardiothorac Surg ; 7: 70, 2012 Jul 18.
Artigo em Inglês | MEDLINE | ID: mdl-22808929

RESUMO

Primary cardiac lymphoma (PCL) is very rare, and is extremely challenging to diagnose due to nonspecific symptoms. When discovered, the right atrium and ventricle are most commonly affected, while diffuse cardiac involvement is uncommon. PCL is fatal unless promptly diagnosed and treated. Herein, we present the case of a 36-year-old immunocompetent male who presented with a 5-year history of non-specific chest symptoms and was diagnosed with primary diffuse cardiac large B-cell lymphoma involving the entire heart.


Assuntos
Bloqueio Atrioventricular/patologia , Neoplasias Cardíacas/patologia , Linfoma de Células B/patologia , Taquicardia Ventricular/patologia , Adulto , Humanos , Masculino
16.
Biochem Biophys Res Commun ; 417(1): 35-42, 2012 Jan 06.
Artigo em Inglês | MEDLINE | ID: mdl-22115783

RESUMO

Autophagy orchestrates programmed cell death via crossroads of complex vesicle trafficking including autophagosome and lysosome interaction. Phafin1, an endosome proteins composed of Pleckstrin homology (PH) and Fab1-YotB-Vac1p-EEA1 (FYVE) domain membrane-binding domains, is involved in caspase-independent apoptosis. We report here that the increased expression of phafin1 and its FYVE domain caused the formation of enlarged endosomes. Phafin1 also modulates the membrane density of certain receptors and participates in endocytosis and autophagy processes. The PH-domain of phafin1 is dispensable for lysosomal targeting. Moreover, the tail-domain of phafin1 provides lysosomal targeting signature and the ability to induce autophagy that is mediated by Rab7 signaling. The results suggest that in addition to its role in endosome transport, phafin1 is also involved in lysosomal targeting and autophagosome formation.


Assuntos
Proteínas Reguladoras de Apoptose/metabolismo , Autofagia , Lisossomos/metabolismo , Fagossomos/metabolismo , Proteínas rab de Ligação ao GTP/metabolismo , Sequência de Aminoácidos , Proteínas Reguladoras de Apoptose/química , Proteínas Reguladoras de Apoptose/genética , Células HEK293 , Humanos , Dados de Sequência Molecular , Estrutura Terciária de Proteína , Proteínas de Transporte Vesicular/metabolismo
17.
Ying Yong Sheng Tai Xue Bao ; 23(11): 3051-6, 2012 Nov.
Artigo em Chinês | MEDLINE | ID: mdl-23431790

RESUMO

A laboratory experiment was conducted to investigate the growth and reproduction of Diachasmimorpha longicaudata (Hymenoptera: Braconidae) reared on the 3rd instar larvae of Bactrocera dorsalis (Diptera: Tephritidae) at 15, 18, 21, 24, 27, and 30 degrees C. Within the range of test temperatures, the generational development time shortened with increasing temperature, from about 45.7 days at 15 degrees C to 15.2 days at 30 degrees C. Excessively low or high temperature had definite inhibition effect on the development of D. longicaudata. At 15 degrees C and 30 degrees C, the survival rate of D. longicaudata at immature stages (i. e. , from egg to adult) was 10.2% and 31.3%, respectively; while at 24-27 degrees C, the survival rate was above 50%. The longevity of D. longicaudata decreased with increasing temperature, and that of the females was usually longer than that of the males. The fecundity of D. Iongicaudata was the highest (74.2 progenies) at 24 degrees C, followed by at 27 degrees C (53.4 progenies), at 21 degrees C (35.7 progenies), and at 18 degrees C (31.6 progenies). At 15 degrees C and 30 degrees C, no more than 20 progenies were observed. At 15-24 degrees C, the female/male ratio increased with increasing temperature, being the highest (0.59) at 24 degrees C; at 21-27 degrees C, females predominated in the progenies populations. The intrinsic increase rate (r(m)) was the highest (0.1318) at 27 degrees C, followed by at 24 degrees C (0.1239), at 21 degrees C (0.0747), at 30 degrees C (0.0318), and at 18 degrees C (0.0187). At 15 degrees C, the intrinsic increase rate and population trend index were -0.0240 and 0.8, respectively, indicating that the population at this temperature presented a negative increasing trend. The favorite temperature range for the development and reproduction of D. longicaudata was from 24 degrees C to 27 degrees C.


Assuntos
Himenópteros/crescimento & desenvolvimento , Reprodução/fisiologia , Temperatura , Animais , Feminino , Fertilidade , Himenópteros/fisiologia , Larva/crescimento & desenvolvimento , Masculino
18.
Ying Yong Sheng Tai Xue Bao ; 22(8): 2126-32, 2011 Aug.
Artigo em Chinês | MEDLINE | ID: mdl-22097377

RESUMO

Geostatistical methods were adopted to characterize the spatial pattern and its variation of Cnaphalocrocis medinalis larvae (Lepidoptera: Crambidae) and Ummeliata insecticeps (Araneida: Linyphiidae) in the habitats of paddy rice neighboring with white melon, tomato, or corn. In the rice growth period, C. medinalis larvae and U. insecticeps presented aggregative distribution, with the spatial range varied from 1.91 to 182.57 m and from 3.70 to 9.70 m, respectively. Isoline map showed that the density of U. insecticeps was spatially and temporally identical with that of C. medinalis larvae, suggesting that U. insecticeps had strong pursuing and control effects on C. medinalis larvae. Among the test neighboring patterns, paddy rice neighboring with white melon had the best performance of U. insecticeps.


Assuntos
Lepidópteros/fisiologia , Oryza/parasitologia , Controle Biológico de Vetores , Aranhas/fisiologia , Verduras/crescimento & desenvolvimento , Agricultura/métodos , Animais , Larva/fisiologia , Oryza/crescimento & desenvolvimento , Zea mays/crescimento & desenvolvimento
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