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1.
ACS Appl Mater Interfaces ; 11(38): 35050-35059, 2019 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-31482704

RESUMO

A yolk-double shell cube-like SnS@N-S codoped carbon (YDSC-SnS@NSC) was delicately tailored by a self-templated and selective etching method as well as a self-assembly strategy. Herein, the ZnSn(OH)6 (ZHS) solid nanocubes were used as templates for the formation of a thin carbon shell that encapsulated the active material, thereby preventing the aggregation and maintaining the uniformity. ZHS is then converted into an intermediate ZnS-SnS2 hybrid by a facile thermal sulfidation process. Because SnS2 is insoluble in acidic condition, it is easy to create a yolk-shell architecture by selectively removing the ZnS component. Further heat treatment promoted the melting of SnS2 and resulted in the decomposition of SnS2 into SnS, which is simultaneously accompanied with a heat- and capillary-driven self-assembly to form a SnS inner core and SnS/C double shell. Such nanostructures with an inner void space and robust double shells are useful in buffering the volume expansion of SnS during lithiation and sodiation. Furthermore, N and S atoms doped into the carbon shell can enhance the electrical conductivity, which is beneficial to the fast charge-transfer kinetics. Because of these advantages, YDSC-SnS@NSC as the anode for Li-ion batteries exhibits improved electrochemical properties. Especially, the YDSC-SnS@NSC anode for Na-ion batteries shows an outstanding rate capability of 257 mA h g-1 at 8 A g-1 and an ultrastable long-term cyclic performance at a current density of 1 A g-1 with a capacity retention of 83.5% (340 mA h g-1 at the first cycle and ultimately reached 284 mA h g-1) and only 0.012% capacity decay per cycle for over 1500 cycles. Such superior electrochemical performance demonstrated that this rationally designed anode is promising for application in both Li- and Na-ion storages.

2.
Clin Rehabil ; 33(9): 1479-1491, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31081365

RESUMO

OBJECTIVE: The aim of this study was to validate a novel pictorial-based Longshi Scale for evaluating a patient's disability by healthcare professionals and non-professionals. DESIGN: Prospective study. SETTING: Rehabilitation departments from a grade A, class 3 public hospital, a grade B, class 2 public hospital, and a private hospital and seven community rehabilitation centers. SUBJECTS: A total of 618 patients and 251 patients with functional disabilities were recruited in a two-phase study, respectively. MAIN MEASURES: Outcome measure: pictorial scale of activities of daily living (ADLs, Longshi Scale). Reference measure: Barthel Index. The Spearman correlation coefficient was used to analyze the validity of Longshi Scale against Barthel Index. RESULTS: In phase 1 study, from March 2016 to August 2016, the results demonstrated that the Longshi Scale was both reliable and valid (intraclass correlation coefficient based on two-way random effect (ICC2,1) = 0.877-0.974 for intra-rater reliability; ICC2,1 = 0.928-0.979; κ = 0.679-1.000 for inter-rater reliability; intraclass correlation coefficient based on one-way random effect (ICC1,1) = 0.921-0.984 for test-retest reliability and Spearman correlation coefficient = 0.836-0.899). In the second phase, in March 2018, results further demonstrated that the Longshi Scale had good inter-rater and intra-rater reliability among healthcare professionals and non-professionals including therapists, interns, and personal care aids (ICC1,1 = 0.822-0.882 on Day 1; ICC1,1 = 0.842-0.899 on Day 7 for inter-rater reliability). In addition, the Longshi Scale decreased assessment time significantly, compared with the Barthel Index assessment (P < 0.01). CONCLUSION: The Longshi Scale could potentially provide an efficient way for healthcare professionals and non-professionals who may have minimal training to assess the ADLs of functionally disabled patients.

3.
Nan Fang Yi Ke Da Xue Xue Bao ; 38(4): 490-495, 2018 Apr 20.
Artigo em Chinês | MEDLINE | ID: mdl-29735453

RESUMO

OBJECTIVE: To explore the relationship between fasting C-peptide (F-CP) and serum uric acid (SUA) in patients with type 2 diabetes mellitus (T2DM). METHODS: A total of 347 hospitalized patients with T2DM were stratified according to F-CP level to analyze the impact of increased F-CP levels on SUA level and the incidence of hyperuricemia (HUA). The patients with an elevated SUA level (>420 µmol/L) and a normal SUA level (≤420 µmol/L) were compared for general data, fasting C-peptide and other clinical indexes. Pearson or Spearman correlation analysis was used to analyze the correlation of SUA level with F-CP levels and other parameters. The risk factors of elevated SUA were analyzed by binary logistic regression, multiple regression analysis and hierarchical interaction analysis. The ROC curve was used to analyze the independent risk factors of elevated SUA and determine the corresponding cut-off values. RESULTS: Compared with those with a normal SUA level, patients with elevated SUA had higher body mass index (BMI), waist-to-hip ratio, F-CP, postprandial 2hC peptide (2hP-CP), triglyceride (TG), homocysteine (HCY), serum creatinine (SCr) level (P<0.05), and a greater percentage of drinking (44.8% vs 32.6%, P=0.006), but had significantly lowered levels of HbA1c, high-density lipoprotein (HDL), and estimated glomerular filtration rate (eGFR) (P<0.05). SUA was found to be positively correlated with F-CP, 2hP-CP, BMI, waist-to-hip ratio, diastolic blood pressure, TG, HCY, SCr, smoking and drinking (P<0.05), and was negatively correlated with gender, age, age of disease onset, HbA1c, HDL and eGFR (P<0.05). SUA level and the incidence of hyperuricemia increasea significantly with F-CP level (P<0.05). F-CP was identified as an independent risk factor for elevated SUA, and gender did not affect the relationship between F-CP and SUA. ROC curve analysis showed that a F-CP level >1.260 ng/mL was associated with a significantly increased risk of hyperuricemia in T2DM patients. CONCLUSION: F-CP is closely related with SUA and may be an independent risk factor of elevated SUA in patients with T2DM.

4.
Complement Ther Med ; 22(5): 858-63, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25440376

RESUMO

OBJECTIVE: To investigate the effect of auricular stimulation in cavum conchae on the glycemic control for patients with type 2 diabetes mellitus. METHODS: Seventy-one cases were treated with auricular electrical stimulator in the cavum choncha for 30 min, once daily for consecutive 3 months. The changes on the fasting plasma glucose (FBG), 2-h postprandial blood glucose after a 75 g oral glucose load (P2BG), glycated hemoglobin (HbA1c), blood urea nitrogen (BUN), serum creatinine (SCr), total cholesterol (TC) and aspartate transaminase (AST) were compared before and after the treatment. RESULTS: The level of the HbA1c was significantly decreased (P<0.05), and there were also statistically significant decreases in BUN, SCr, TC and AST after the treatment (P<0.05). A few patients (n=7) reduced the dose of the hypoglycemic agents in response to repeated hypoglycemia during the treatment. CONCLUSION: The stimulation in the cavum conchae of patients with types 2 diabetes mellitus may help decrease HbA1c, BUN, SCr, TC and AST, and may be an effective treatment for type 2 diabetes mellitus.


Assuntos
Auriculoterapia/métodos , Glicemia/metabolismo , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/terapia , Adulto , Idoso , Orelha Externa/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
5.
Zhongguo Zhen Jiu ; 32(3): 198-200, 2012 Mar.
Artigo em Chinês | MEDLINE | ID: mdl-22471126

RESUMO

OBJECTIVE: To explore the intervention effect of the auricular stimulator in the cavum concha for diabetes. METHODS: Forty-five cases were treated with auricular simulator in the cavum concha for 30 min, once daily for consecutive 3 months. The changes of the fasting plasma glucose (FBG), blood glucose load after 2-hour 75 g oral glucose tolerance test (P2 BG)and glycosylated hemoglobin (HbA1c) were compared before and after treatment. RESULTS: The level of the HbA1c was obviously decreased (P < 0.05, P < 0.01), and there were also statistically significant differences in FBG and P2 BG after the treatment (P < 0.05, P < 0.01). CONCLUSION: With the auricular stimulator, the stimulation in the cavum concha is benefit for the improvement of HbA1c of the diabetes.


Assuntos
Acupuntura Auricular , Diabetes Mellitus/metabolismo , Diabetes Mellitus/terapia , Glucose/metabolismo , Adulto , Idoso , Feminino , Hemoglobina A Glicada/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade
6.
Wei Sheng Yan Jiu ; 41(1): 96-101, 2012 Jan.
Artigo em Chinês | MEDLINE | ID: mdl-22443066

RESUMO

OBJECTIVE: To develop an assay for the simultaneous detection of 7 common foodborne pathogens with xMAP liquid chip in a single-tube reaction. METHODS: Seven specific primers and probes were designed and synthesized based on the target gene sequences from GenBank. Target bacterial sequences were amplified by asymmetric PCR. The biotinylated products were hybridized to seven probe beads in a multiplex reaction and analyzed by using streptavidin conjugated to a fluorescent reporter molecule. The developed liquid chip xMAP assay was used to test 140 strains of bacteria and then 56 food samples. RESULTS: No cross-reaction and false signals were observed. The detection limit was 1 - 100 pg and 10(5) - 10(6) cfu/ml. The results tested by xMAP were in accordance with the traditional culture method. CONCLUSION: The processing of xMAP liquid chip assay, including DNA preparation and sample detection, could be finished within 3.5 hours and could be applied to the classification and identification of foodborne pathogens in the food safety monitoring.


Assuntos
Técnicas Bacteriológicas , Microbiologia de Alimentos/métodos , Salmonella/isolamento & purificação , Staphylococcus aureus/isolamento & purificação , Vibrio parahaemolyticus/isolamento & purificação , Bactérias/genética , Bactérias/isolamento & purificação , Escherichia coli O157/genética , Escherichia coli O157/isolamento & purificação , Contaminação de Alimentos , Microesferas , Técnicas de Amplificação de Ácido Nucleico , Hibridização de Ácido Nucleico , Sondas de Oligonucleotídeos , Reação em Cadeia da Polimerase/métodos , Salmonella/genética , Staphylococcus aureus/genética , Vibrio parahaemolyticus/genética
7.
Clin Imaging ; 36(1): 8-13, 2012 Jan-Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22226436

RESUMO

OBJECTIVES: This study aimed to analyze the computed tomographic (CT) various findings of mucoepidermoid carcinoma of the lung and to improve the diagnostic efficacy for such tumor. MATERIALS AND METHODS: Sixteen consecutive patients with mucoepidermoid carcinoma of the lung confirmed by pathology were reviewed retrospectively. All the patients had undergone unenhanced and contrast-enhanced examinations; one of them also had undergone 18F-FDG PET/CT examinations. RESULTS: There were 6 males and 10 females with a mean age of 34.1 years. On CT plain scan, 14 out of 16 cases showed a well-defined endobronchus mass (n=12) or single peripheral nodule (n=2) with obstructive pneumonia or atelectasis (n=4), one case appeared a cavity in the tumor mass, and one presented diffuse circumferential wall thickening. Punctate calcification was observed in four cases (25%). Tumors showed mild (n=4, 25 %), moderate (n=6, 37.5%), and marked (n=6, 37.5%) degrees of contrast enhancement. Two patients had mediastinal lymph node metastasis, and one of them also had bone metastasis. CONCLUSIONS: Mucoepidermoid carcinoma of the lung likely affects young adults. The common findings included a well-defined ovoid or rounded intraluminal mass; and uncommon findings included cavitation, diffuse thickening, or spiculation. Although CT manifestations of it are variable and nonspecific, a well-defined ovoid or lobulated intraluminal or lung peripheral mass with moderate to marked heterogeneous contrast enhancement may suggest the diagnosis of mucoepidermoid carcinoma of the lung. It should be included in the differential diagnosis of regional tumors.


Assuntos
Carcinoma Mucoepidermoide/diagnóstico por imagem , Carcinoma Mucoepidermoide/secundário , Neoplasias Pulmonares/diagnóstico por imagem , Radiografia Torácica/métodos , Tomografia Computadorizada por Raios X/métodos , Adulto , Feminino , Humanos , Metástase Linfática , Masculino , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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