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Prensa méd. argent ; 105(9 especial): 526-531, oct 2019. tab, fig
Artigo em Inglês | LILACS, BINACIS | ID: biblio-1046381


In the case of lung cancer, surgery is the only method of therapy that gives the patient a chance to recover. However, even after radical surgery, up to 50 ­ 60 % of patients die in the subsequent five years from the disease progression. This study was aimed at identifying the technical particularities of surgery, depending on the side of the lung affected by a tumor and the possibility of applying the methods that improve the results of surgical therapy. The study was performed at the Thoracic Department of the Republican Clinical Oncology Dispensary in Ufa and the 1st Surgical Department of the Regional Oncology Center of the Regional Clinical Hospital in Khanty- Mansiysk. The study involved a total of 156 patients (including 148 male and eight female patients). The main result of the study has been the confirmation of the advantages of bronchoplastic surgery, which do not increase post-surgery mortality and improve the post-surgery period, and the relevant principles of preserving surgery.

Humanos , Cirurgia Geral/métodos , Procedimentos Cirúrgicos Operatórios/mortalidade , Mortalidade , Neoplasias Pulmonares/cirurgia
Patol Fiziol Eksp Ter ; (4): 20-4, 2009.
Artigo em Russo | MEDLINE | ID: mdl-20143526


Tetanus anatoxin was shown to have a stimulant effect on the cardiovascular system and its autonomic regulation, which produced a longer posthemorrhagic survival in the controls with the least pronounced dystrophic changes in the myocardium. Prior vaccination with diphtheria anatoxins was found to promote animals' survival, by reducing reperfusion injury in the presence of long-term systemic hypoperfusion, early exhaustion of sympathetic autonomic cardiac rhythm regulation, and myocardial dystrophic and necrobiotic changes resulting in the development of cardiosclerosis.

Vacina contra Difteria e Tétano/farmacologia , Coração/fisiopatologia , Traumatismo por Reperfusão Miocárdica/fisiopatologia , Recuperação de Função Fisiológica/efeitos dos fármacos , Choque Hemorrágico/fisiopatologia , Sistema Nervoso Simpático/fisiopatologia , Vacinação , Animais , Cães , Feminino , Coração/inervação , Masculino , Traumatismo por Reperfusão Miocárdica/etiologia , Miocárdio/patologia , Choque Hemorrágico/complicações , Fatores de Tempo
Patol Fiziol Eksp Ter ; (4): 10-1, 2008.
Artigo em Russo | MEDLINE | ID: mdl-19198265


Electrocardiographic and echocardiographic parameters were studied in 364 patients admitted to the department of thoracic surgery of Bashkirian Medical University clinic in 1997-2006. The patients had hemorrhagic shock due to acute traumatic blood loss or long operative intervention with massive hemorrhage. It was found that preliminary vaccination with tetanus antitoxin improves a course of posthemorrhagic period, hemodynamic restoration and survival of the patients.

Hemodinâmica/efeitos dos fármacos , Fatores Imunológicos/administração & dosagem , Choque Hemorrágico/fisiopatologia , Antitoxina Tetânica/administração & dosagem , Procedimentos Cirúrgicos Torácicos , Vacinação , Adulto , Bashkiria , Intervalo Livre de Doença , Feminino , Humanos , Masculino , Estudos Retrospectivos , Choque Hemorrágico/cirurgia
Patol Fiziol Eksp Ter ; (3): 17-8, 2006.
Artigo em Russo | MEDLINE | ID: mdl-17002043


Chronic experiments for 5 weeks made in 41 mongrel adult dogs have shown that prevaccination with diphtheria antitoxin has a negative effect on myocardial and hemodynamic restoration after resustitation. The dogs have arrhythmia, survival of the animals is worse. However, such prevaccination improved survival of the animals due to reduction of reperfusion trauma in animals after hemorrhagic shock in spite of conduction disorders and myocardial ischemia.

Toxoide Diftérico/efeitos adversos , Sistema de Condução Cardíaco/efeitos dos fármacos , Isquemia Miocárdica/fisiopatologia , Traumatismo por Reperfusão Miocárdica/fisiopatologia , Ressuscitação , Animais , Bradicardia/induzido quimicamente , Cães , Imunização/efeitos adversos , Reperfusão Miocárdica , Choque Hemorrágico/fisiopatologia
Patol Fiziol Eksp Ter ; (2): 25-7, 2006.
Artigo em Russo | MEDLINE | ID: mdl-16841656


Chronic experiments lasting for 5 weeks were carried out in 40 nonpedigree mature dogs. It has been detected that preliminary immunization with staphylococcus anatoxin potentiates the compensation mechanisms in the course of postresuscitation period, stimulates cell proliferation by increasing cardiac output that is an adaptive reaction of the cardiovascular system in postresuscitation period and provides optimal metabolism of the organism.

Débito Cardíaco/efeitos dos fármacos , Imunização , Ressuscitação , Toxoide Estafilocócico/uso terapêutico , Animais , Proliferação de Células/efeitos dos fármacos , Cães , Miocárdio/patologia , Choque Hemorrágico/terapia , Toxoide Estafilocócico/administração & dosagem