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1.
Sensors (Basel) ; 21(22)2021 Nov 17.
Artigo em Inglês | MEDLINE | ID: mdl-34833708

RESUMO

We designed simply fabricated, highly sensitive, and cost-effective dual-polymer-coated Fabry-Perot interferometer (DFPI)-based temperature sensors by employing thermosensitive polymers and non-thermosensitive polymers, as well as different two successive dip-coating techniques (stepwise dip coating and polymer mixture coating). Seven sensors were fabricated using different polymer combinations for performance optimization. The experiments demonstrated that the stepwise dip-coated dual thermosensitive polymer sensors exhibited the highest sensitivity (2142.5 pm °C-1 for poly(methyl methacrylate)-polycarbonate (PMMA_PC) and 785.5 pm °C-1 for poly(methyl methacrylate)- polystyrene (PMMA_PS)). Conversely, the polymer-mixture-coated sensors yielded low sensitivities (339.5 pm °C-1 for the poly(methyl methacrylate)-polycarbonate mixture (PMMA_PC mixture) and 233.5 pm °C-1 for the poly(methyl methacrylate)-polystyrene mixture (PMMA_PS mixture). Thus, the coating method, polymer selection, and thin air-bubble-free coating are crucial for high-sensitivity DFPI-based sensors. Furthermore, the DFPI-based sensors yielded stable readouts, based on three measurements. Our comprehensive results confirm the effectiveness, reproducibility, stability, fast response, feasibility, and accuracy of temperature measurements using the proposed sensors. The excellent performance and simplicity of our proposed sensors are promising for biomedical, biochemical, and physical applications.


Assuntos
Polímeros , Polimetil Metacrilato , Poliestirenos , Reprodutibilidade dos Testes , Temperatura
2.
Nanomaterials (Basel) ; 11(4)2021 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-33924664

RESUMO

In this study, a simply structured perovskite-based ultraviolet C (UVC) sensor was prepared using a one-step, low-temperature solution-processing coating method. The UVC sensor utilized CH3NH3PbBr3 perovskite as the light-absorbing layer. To improve the characteristics of CH3NH3PbBr3, an antisolvent process using toluene and the addition of CH3NH3Cl were introduced. The device with these modifications exhibited a response rise/fall time of 15.8/16.2 ms, mobility of 158.7 cm2/V·s, responsivity of 4.57 mA/W, detectivity of 1.02 × 1013 Jones, and external quantum efficiency of 22.32% under the 254-nm UV illumination. Therefore, this methodology could be a good approach in facilitating UVC detection.

3.
J Nanosci Nanotechnol ; 21(8): 4362-4366, 2021 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-33714328

RESUMO

The perovskite solar cell is capable of energy conversion in a wide range of wavelengths, from 300 nm to 800 nm, which includes the entire visible region and portions of the ultraviolet and infrared regions. To increase light transmittance of perovskite solar cells and reduce manufacturing cost of perovskite solar cells, soda-lime glass and transparent conducting oxides, such as indium tin oxide and fluorine-doped tin oxide are mainly used as substrates and light-transmitting electrodes, respectively. However, it is evident from the transmittance of soda-lime glass and transparent conductive oxides measured via UV-Vis spectrometry that they absorb all light near and below 310 nm. In this study, a transparent Mn-doped ZnGa2O4 film was fabricated on the incident surface of perovskite solar cells to obtain additional light energy by down-converting 300 nm UV light to 510 nm visible light. We confirmed the improvement of power efficiency by applying a ZnGa2O4:Mn down-conversion layer to perovskite solar cells.

4.
J Nanosci Nanotechnol ; 21(8): 4383-4387, 2021 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-33714331

RESUMO

Organic material-based solar cell devices such as perovskite solar cells (PSCs) have attracted attention as renewable energy resources with low production cost, lightweight, wearable device applications, and large-area processability. To enhance device performance, many research groups have attempted to develop new materials and structures. Metal electrode materials play an important role in solar energy conversion in PSCs, owing to the ohmic contact and contact resistance between metal negative electrodes and photoactive layers. Until recently, conventional metal sources such as Ag, Au, or Cu have been used as electrodes. In this study, PSCs were employed in various metal negative electrodes using a thermal evaporator. The authors investigated the effect of metal negative electrodes on PSCs.

5.
J Nanosci Nanotechnol ; 21(8): 4336-4340, 2021 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-33714324

RESUMO

In this study, a UVC sensor was implemented using CH3NH3PbI3, a perovskite material. The UV sensor made with a p-i-n structure uses PEDOT:PSS as the p-type material and ZnO as the n-type material. The fabricated device shows a responsivity of 1.60 mA/W and a detectivity of 2.25×1010 Jones under 254 nm illumination with a power density of 1.02 mW/cm² at 2 V. In addition, the manufactured UV sensor is a self-powered perovskite-based UV sensor that can operate without external bias. Therefore, this UVC sensor can have applications in various fields.

6.
J Nanosci Nanotechnol ; 21(8): 4367-4371, 2021 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-33714329

RESUMO

The perovskite film-manufactured via a one-step method-was superficially improved through an anti-solvent process to increase solar cell efficiency. Although perovskite synthesis proceeds rapidly, a significant amount of lead iodide residue remains. Well-placed lead iodide in perovskite grains prevents electron-hole recombination; however, when irregularly placed, it interferes with the movement of electron and holes. In this study, we focused on improving the crystallinity of the perovskite layer, as well as reducing lead iodide residues by adding a methylammonium halide material to the anti-solvent. Methylammonium iodide in chlorobenzene used as an anti-solvent reduces lead iodide residues and improves the crystallinity of formamidinium lead iodide perovskite. The improved crystallinity of the perovskite layer increased the absorbance and, with reduced lead iodide residues, increased the efficiency of the perovskite solar cell by 1.914%.

7.
J Nanosci Nanotechnol ; 21(3): 1795-1798, 2021 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-33404450

RESUMO

Ultraviolet (UV) sensors have application in many different areas such as flame and hightemperature detection, space research, environmental monitoring, ozone layer monitoring, and missile warning systems. Among them, ZnO thin-film-based UV sensors have been attracting attention among research groups and are being continuously studied. The incorporation of ZnO/organic hybrid structures into solar cells and other photoelectrochemical applications has been extensively reported. However, little research has been performed on ZnO/polymer-based UV sensors. In this study, a simple UV sensor based on an Al:ZnO/polymer is demonstrated. Al-doped ZnO enables effective UV detection with excellent performance at low operating voltages using a simple and inexpensive process.

8.
J Nanosci Nanotechnol ; 21(3): 1804-1808, 2021 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-33404452

RESUMO

The power conversion efficiency of perovskite solar cells, which are next-generation photovoltaic cells, has rapidly increased up to 20% through ongoing research and development. Recently, various methods have been employed to increase the active area of the mesoporous layer in perovskite solar cells. In this study, the particle aggregation of the TiO2 was controlled by adding Ti-diisopropoxide bis to the mesoporous layer solution; thus, the contact area between the mesoporous layer and perovskite layer was increased. The amount of Ti-diisopropoxide bis added to the mesoporous layer solution was adjusted to prevent the inhibition of electron transport caused by separation of particles and instability of mesoporous layer. To evaluate the changes in the characteristics of the perovskite solar cells due to the TiO2 particle aggregation in the mesoporous layer, X-ray diffraction and spectrophotometric absorbance, as well as cross-sectional and surface scanning electron microscopy measurement were performed, and the current density-voltage curve, power conversion efficiency and other properties were evaluated under solar simulator. It was found that the mesoporous layer was improved due to its enlarged contact area, and hence, can be expected to improve the efficiency of perovskite solar cells.

9.
JMIR Mhealth Uhealth ; 8(12): e21733, 2020 12 23.
Artigo em Inglês | MEDLINE | ID: mdl-33355537

RESUMO

BACKGROUND: Diet-tracking mobile apps have gained increased interest from both academic and clinical fields. However, quantity-focused diet tracking (eg, calorie counting) can be time-consuming and tedious, leading to unsustained adoption. Diet quality-focusing on high-quality dietary patterns rather than quantifying diet into calories-has shown effectiveness in improving heart disease risk. The Healthy Heart Score (HHS) predicts 20-year cardiovascular risks based on the consumption of foods from quality-focused food categories, rather than detailed serving sizes. No studies have examined how mobile health (mHealth) apps focusing on diet quality can bring promising results in health outcomes and ease of adoption. OBJECTIVE: This study aims to design a mobile app to support the HHS-informed quality-focused dietary approach by enabling users to log simplified diet quality and view its real-time impact on future heart disease risks. Users were asked to log food categories that are the main predictors of the HHS. We measured the app's feasibility and efficacy in improving individuals' clinical and behavioral factors that affect future heart disease risks and app use. METHODS: We recruited 38 participants who were overweight or obese with high heart disease risk and who used the app for 5 weeks and measured weight, blood sugar, blood pressure, HHS, and diet score (DS)-the measurement for diet quality-at baseline and week 5 of the intervention. RESULTS: Most participants (30/38, 79%) used the app every week and showed significant improvements in DS (baseline: mean 1.31, SD 1.14; week 5: mean 2.36, SD 2.48; 2-tailed t test t29=-2.85; P=.008) and HHS (baseline: mean 22.94, SD 18.86; week 4: mean 22.15, SD 18.58; t29=2.41; P=.02) at week 5, although only 10 participants (10/38, 26%) checked their HHS risk scores more than once. Other outcomes, including weight, blood sugar, and blood pressure, did not show significant changes. CONCLUSIONS: Our study showed that our logging tool significantly improved dietary choices. Participants were not interested in seeing the HHS and perceived logging diet categories irrelevant to improving the HHS as important. We discuss the complexities of addressing health risks and quantity- versus quality-based health monitoring and incorporating secondary behavior change goals that matter to users when designing mHealth apps.


Assuntos
Dieta , Cardiopatias , Aplicativos Móveis , Peso Corporal , Dieta/normas , Dieta/estatística & dados numéricos , Cardiopatias/prevenção & controle , Humanos , Obesidade/prevenção & controle
10.
J Nanosci Nanotechnol ; 20(11): 7081-7086, 2020 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-32604561

RESUMO

A ZnGa2O4:Eu3+ layer was deposited on the incident surface of a perovskite solar cell (PSC) to convert ultraviolet rays into current within the solar cell. The ZnGa2O4:Eu3+ layer was deposited using the sol-gel method, and the thickness of the film was controlled using the number of spin coatings. When the coating was applied six times, a layer with almost no oscillation due to reflection was fabricated. It was confirmed that the efficiency of the PSC was not adversely affected by the coating. In addition, generation of a current by converting ultraviolet radiation within the solar cell was confirmed.

11.
J Nanosci Nanotechnol ; 20(11): 7130-7134, 2020 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-32604570

RESUMO

Over the past three decades, the development of renewable energy technologies has attracted significant attention to overcome both environmental pollution and global warming. Recently, a new type of solar cell based on an organic-inorganic halide perovskite material has been developed. Perovskite solar cells (PSC) were first reported in 2009; their efficiencies increased rapidly from 3.8% to 22%. PSCs have many advantages owing to their use of simple processing technology and stable materials. Perovskite materials have a general formula of ABX, where A is generally methyl ammonium CH3NH3+ (MA), B is a metal ion, such as Pb or Sn, and × represents a halogen ion. A distinct advantage of lead-based perovskites (i.e., MAPbX3) is that their band gaps can be easily tuned, from 1.2 to 2.3 eV, by varying their compositions and anions. Titanium dioxide is as often used as an electron transport layer due to its high chemical and optical stability, non-toxicity, low cost, and resistance to corrosion. TiO2 films can be characterized by the defects in their preparation, such as density fluctuations, pinholes, and cracks; these defects can reduce electrical conductivity and cause recombination. In this study, we have demonstrated that the electrical conductivity of TiO2 thin films is improved by its doping with Al3+. When applied to a PSC, the doped thin film improves the charge transfer of the solar cell and increases its efficiency. Our results suggest that Al3+ nanoparticles in the TiO2 layer may contribute to the improvement of the PSC.

12.
Materials (Basel) ; 13(14)2020 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-32679872

RESUMO

One of the biggest challenges in the commercialization of tin dioxide (SnO2)-based lithium-ion battery (LIB) electrodes is the volume expansion of SnO2 during the charge-discharge process. Additionally, the aggregation of SnO2 also deteriorates the performance of anode materials. In this study, we prepared SnO2 nanoflowers (NFs) using nanocrystalline cellulose (CNC) to improve the surface area, prevent the particle aggregation, and alleviate the change in volume of LIB anodes. Moreover, CNC served not only as the template for the synthesis of the SnO2 NFs but also as a conductive material, after annealing the SnO2 NFs at 800 °C to improve their electrochemical performance. The obtained CNC-SnO2NF composite was used as an active LIB electrode material and exhibited good cycling performance and a high initial reversible capacity of 891 mA h g-1, at a current density of 100 mA g-1. The composite anode could retain 30% of its initial capacity after 500 charge-discharge cycles.

13.
J Nanosci Nanotechnol ; 20(9): 5491-5497, 2020 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-32331123

RESUMO

Perovskite solar cells (PSCs) represent the third generation of solar cells that comprise a semiconductor electrode, a counter electrode, and an electrolyte. Perovskite solar cells (PSCs) have been comprehensively researched and led to an impressive improvement in a short period of time as cheaper alternatives to silicon solar cells due to their high energy-conversion efficiency and low production cost. Tin oxide (SnO2) has attracted attention as a promising candidate for electron transport material of perovskite solar cells, because it can be easily processed by low annealing temperature and solution processing method. However, in the fabrication of SnO2 electron transfer layer (ETL) via the conventional solution method, it is greatly difficult to increase the size of the substrate by the solution treatment method or to commercialize it. In this work, we report the photovoltaic characteristics of SnO2 based electron transport layer for perovskite solar cells (PSCs) fabricated by the thermal-evaporation processing method. The deposited SnO2 layer with the thermal evaporator is known to be not crystallographically stable. To solve this problem, we performed the annealing process at relatively low temperature (below 200 °C). As a result, we could confirm the optimum annealing temperature and we could demonstrate PSCs with thermally deposited SnO2 as the compact electron transport layer through a low-temperature annealing process. It would contribute to new opportunities in commercialization and development of perovskite solar cells.

14.
Sensors (Basel) ; 20(3)2020 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-32024014

RESUMO

The exploration of novel polymers for temperature sensing with high sensitivity has attracted tremendous research interest. Hence, we report a polystyrene-coated optical fiber temperature sensor with high sensitivity. To enhance the temperature sensitivity, flat, thin, smooth, and air bubble-free polystyrene was coated on the edge surface of a single-mode optical fiber, where the coating thickness was varied based on the solution concentration. Three thicknesses of the polystyrene layer were obtained as 2.0, 4.1, and 8.0 µm. The temperature sensor with 2.0 µm thick polystyrene exhibited the highest temperature sensitivity of 439.89 pm °C-1 in the temperature range of 25-100 °C. This could be attributed to the very uniform and thin coating of polystyrene, along with the reasonable coefficient of thermal expansion and thermo-optic coefficient of polystyrene. Overall, the experimental results proved the effectiveness of the proposed polystyrene-coated temperature sensor for accurate temperature measurement.

15.
J Nanosci Nanotechnol ; 20(1): 552-556, 2020 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-31383209

RESUMO

Recently, single-crystal silicon solar cells have achieved efficiencies of 25%. However, their production is energy-demanding and relatively expensive. Therefore, photovoltaic cells based on organic- inorganic hybrid perovskites have attracted considerable attention owing to their high conversion efficiencies, simple preparation, and potentially low production costs. In this study, we investigated the effect of Fe3+ doped into a compact and mesoporous layer of TiO2 on the efficiency of the resultant perovskite solar cell (PSC). The efficiencies achieved for PSCs with Fe3+/TiO2 were higher than those for cells with pure TiO2 nanoparticles. The samples were characterized by X-ray diffraction, scanning electron microscopy, ultraviolet-visible spectroscopy, and current-voltage measurements. The photoelectrode PSC exhibited a high light-to-electric-energy conversion efficiency under a simulated solar light irradiation of 100 mW/cm² (AM 1.5). Our results suggest that Fe3+ nanoparticles in the TiO2 layer may contribute to the performance improvement of the PSC.

16.
Int J Mol Med ; 43(4): 1859-1865, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30720064

RESUMO

Inhibition of over­activated inflammation has been demonstrated as one of the most efficient strategies for treating inflammatory diseases. In the present study, 6­formyl umbelliferone (6FU) was used to evaluate its anti­inflammatory effects on lipopolysaccharide (LPS)­stimulated RAW 264.7 macrophages. 6FU inhibited chronic inflammatory processes, including increasing nitric oxide levels, and the expression of pro­inflammatory genes and producing cytokines was investigated by a nitrite assay and reverse transcription­polymerase chain reaction, respectively. Nitric oxide and pro­inflammatory cytokines, including tumor necrosis factor­α, interleukin (IL)­1ß and IL­6 were decreased by treatment with 6FU, without cell cytotoxicity in LPS­stimulated RAW 264.7 cells, which was measured by a WST­1 assay. In the western blot analysis, the expression levels of phosphorylated extracellular signal­regulated kinase (ERK)1/2 was downregulated in 6FU­treated cells. Furthermore, in the western blotting and immunofluorescence staining results, translocation activities of ERK1/2 and NF­κB from the cytoplasm to the nucleus were suppressed, which may inhibit translation of numerous proteins associated with pro­inflammation, including inducible nitric oxide synthase and cyclooxygenase­2. Therefore, based on these results, it was suggested that 6FU may be a potential candidate for the development of agents against chronic inflammation.


Assuntos
Anti-Inflamatórios/farmacologia , Sistema de Sinalização das MAP Quinases/efeitos dos fármacos , NF-kappa B/metabolismo , Umbeliferonas/farmacologia , Animais , Sobrevivência Celular/efeitos dos fármacos , Ciclo-Oxigenase 2/metabolismo , Citocinas/genética , Citocinas/metabolismo , Ativação Enzimática/efeitos dos fármacos , Lipopolissacarídeos , Camundongos , Proteínas Quinases Ativadas por Mitógeno/metabolismo , Óxido Nítrico/biossíntese , Óxido Nítrico Sintase Tipo II/metabolismo , Fosforilação/efeitos dos fármacos , Transporte Proteico/efeitos dos fármacos , Células RAW 264.7 , RNA Mensageiro/genética , RNA Mensageiro/metabolismo
17.
J Nanosci Nanotechnol ; 19(3): 1549-1553, 2019 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-30469221

RESUMO

A uniform compact layer is essential for obtaining high-efficiency perovskite solar cells (PSCs). This is because direct contact between the FTO glass substrate and the perovskite layer should be blocked to suppress electron recombination and to collect electrons. In the present study, PSCs were fabricated using sputtered TiO2 compact layers prepared at different deposition times. The structure, morphology, and electrical properties of the sputter deposited TiO2 compact layer were compared to those of a spin coated TiO2 film. The TiO2 compact layer prepared by the sputtering process was very smooth and inhibited electron recombination at the FTO interface, resulting in a higher open circuit voltage and a higher short circuit current density. A photoelectric conversion efficiency of 13.37% was obtained using the TiO2 compact layer deposited for 30 min.

18.
J Nanosci Nanotechnol ; 19(3): 1615-1619, 2019 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-30469232

RESUMO

In this work, to explore the influence of phosphor additives on the conversion efficiency of perovskite solar cells (PSC), we introduce a Y3Al5O12:Ce3+ (YAG:Ce3+) phosphor layer. The YAG:Ce3+ nanophosphor acts as a light down-converting material to absorb high energy photons and emit lower energy photons that match well with the absorption of the perovskite layer, yielding more excited photo-generated electron-hole pairs. Therefore, the incident solar light can be harvested more effectively. We used 8 mg/ml of TiO2 mixed with YAG:Ce3+ in the PSCs and realized a light-to-electric energy conversion efficiency of 13.34%, a short circuit current density of 21.23 mA/cm², an open circuit voltage of 0.97 V, and a FF of 55.96%. Higher efficiencies were achieved for PSCs with phosphor-mixed TiO2 than for cells with pure TiO2 nanoparticles. The samples were characterized by XRD, SEM, UV-vis, PL, and IV-curves. Photoelectrode DSSC with light-to-electric energy conversion efficiency was achieved under a simulated solar light irradiation of 100 mW/cm² (AM 1.5).

19.
Small ; 14(41): e1802933, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30216668

RESUMO

Nickel sulfides have drawn much attention with the benefits of a high redox activity, high electrical conductivity, low cost, and fabrication ease; however, these metal sulfides are susceptible to mechanical degradation regarding their cycling performance. Conversely, hollow carbon shells exhibit a substantial electrochemical steadiness in energy storage applications. Here, the design and development of a novel millerite core-nitrogen-doped carbon hollow shell (NiS-NC HS) structure for electrochemical energy storage is presented. The nitrogen-doped carbon hollow shell (NC HS) protects against the degradation and the millerite-core aggregation, giving rise to an excellent rate capability and stability during the electrochemical charging-discharging processes, in addition to improving the NiS-NC HS conductivity. The NiS-NC HS/18h supercapacitor electrode displays an outstanding specific capacitance of 1170.72 F g-1 (at 0.5 A g-1 ) and maintains 90.71% (at 6 A g-1 ) of its initial capacitance after 4000 charge-discharge cycles, owing to the unique core-shell structure. An asymmetric-supercapacitor device using NiS-NC HS and activated-carbon electrodes exhibits a high power and energy density with a remarkable cycling stability, maintaining 89.2% of its initial capacitance after 5000 cycles.

20.
Int J Mol Med ; 41(2): 1103-1109, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29207042

RESUMO

Lovastatin is a 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor that is clinically used for the prevention of cardiovascular diseases. Although it has been reported that lovastatin has anti-inflammatory properties in several studies, how lovastatin regulates the inflammation is still unclear. To evaluate the effect of lovastatin on nitric oxide production (NO) in RAW264.7 macrophages, NO production assay was performed. Also, cell viability was measured to confirm cytotoxicity. Level of tumor necrosis factor-α (TNF-α) transcription was measured by reverse transcription polymerase chain reaction (RT-PCR) from total RNA in RAW264.7 cells. Western blot analysis and immunofluorescence staining were used to investigate the regulation of lovastatin on the expression, phosphorylation, and nuclear translocation of cellular proteins. The results of the present study revealed that lovastatin reduced nitric oxide production via the reduction of inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. The mRNA level of TNF-α was reduced in presence of lovastatin. In addition, lovastatin downregulated histone deacetylase 1 (HDAC1), resulting in the accumulation of acetylated histone H3 and heat shock protein 70. Furthermore, the expression of phosphoinositide 3-kinase catalytic subunits α and ß was reduced under lovastatin treatment, and the phosphorylation of Akt and mammalian target of rapamycin was consequently inhibited. Lovastatin also inhibited the phosphorylation of inhibitor of nuclear factor (NF)-κBα and the translocation of NF-κB into the nucleus. Therefore, the present study demonstrates that lovastatin inhibits the expression of pro-inflammatory mediators, including iNOS and TNF-α, through the suppression of HDAC1 expression, PI3K/Akt phosphorylation and NF-κB translocation in LPS-stimulated RAW264.7 macrophage cells.


Assuntos
Anti-Inflamatórios/administração & dosagem , Histona Desacetilase 1/genética , Inflamação/tratamento farmacológico , Lovastatina/administração & dosagem , Animais , Regulação da Expressão Gênica/efeitos dos fármacos , Histona Desacetilase 1/antagonistas & inibidores , Humanos , Inflamação/induzido quimicamente , Inflamação/genética , Inflamação/patologia , Lipopolissacarídeos/toxicidade , Macrófagos/efeitos dos fármacos , Macrófagos/patologia , Camundongos , NF-kappa B/genética , Óxido Nítrico Sintase Tipo II/genética , Fosfatidilinositol 3-Quinases/genética , Proteínas Proto-Oncogênicas c-akt/genética , Células RAW 264.7 , Serina-Treonina Quinases TOR/genética , Fator de Necrose Tumoral alfa/genética
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