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1.
BMJ ; 369: m877, 2020 Apr 06.
Artigo em Inglês | MEDLINE | ID: mdl-32253188

RESUMO

The studyHodkinson A, Kontopantelis E, Adeniji C, et al. Accelerometer- and pedometer-based physical activity interventions among adults with cardiometabolic conditions: a systematic review and meta-analysis JAMA Network Open 2019;2:e1912895.This study was funded by the NIHR School for Primary Care Research (project number 390 ESWG Workstream 3).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000880/pedometers-can-help-people-get-more-active-as-part-of-an-exercise-programme.


Assuntos
Actigrafia/instrumentação , Exercício Físico , Terapia por Exercício , Humanos , Atenção Primária à Saúde
2.
BMJ ; 368: m517, 2020 Mar 23.
Artigo em Inglês | MEDLINE | ID: mdl-32205307

RESUMO

The studyPowell J, Atherton H, Williams V, et al. Using online patient feedback to improve NHS services: the INQUIRE multimethod study. Health Serv Deliv Res 2019;7:38.This project was funded by the NIHR Health Services and Delivery Research programme (project number HS&DR 14/04/48).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000861/online-patient-feedback-is-mostly-positive-but-is-not-being-used-effectively.


Assuntos
Retroalimentação , Satisfação do Paciente , Medicina Estatal , Participação da Comunidade , Humanos , Medicina Estatal/normas , Reino Unido
3.
BMJ ; 368: m514, 2020 03 11.
Artigo em Inglês | MEDLINE | ID: mdl-32161036

RESUMO

The studyThe CRASH-3 Trial Collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. Lancet 2019;394:1713-23.This trial was funded by NIHR Health Technology Assessment Programme (project number 14/190/01), JP Moulton Charitable Trust, Department of Health and Social Care, Department for International Development, Global Challenges Research Fund, Medical Research Council, and the Wellcome Trust (Joint Global Health Trials scheme).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000870/tranexamic-acid-following-mild-to-moderate-traumatic-brain-injury-is-safe-and-reduces-deaths.


Assuntos
Antifibrinolíticos , Lesões Encefálicas Traumáticas , Doenças Vasculares , Humanos , Avaliação da Tecnologia Biomédica , Ácido Tranexâmico
4.
BMJ ; 368: m512, 2020 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-32144210

RESUMO

The studyHewlett S, Almeida C, Ambler N, et al. Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT). Ann Rheum Dis 2019;78:465-72.Hewlett S, Almeida C, Ambler N, et al. Group cognitive behavioural programme to reduce the impact of rheumatoid arthritis fatigue: the RAFT RCT with economic and qualitative evaluations. Health Technol Assess 2019;23:57.This project was funded by the NIHR Health Technology Assessment Programme (project number 11/112/01).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000860/group-cognitive-behavioural-courses-may-reduce-fatigue-from-rheumatoid-arthritis.


Assuntos
Artrite Reumatoide/complicações , Terapia Cognitivo-Comportamental/métodos , Fadiga/prevenção & controle , Fadiga/terapia , Psicoterapia de Grupo/métodos , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
5.
BMJ ; 368: m520, 2020 03 25.
Artigo em Inglês | MEDLINE | ID: mdl-32213484

RESUMO

The studyPalmer R, Dimairo M, Cooper C, et al. Self-managed, computerised speech and language therapy for patients with chronic aphasia post-stroke compared with usual care or attention control (Big CACTUS): a multicentre, single-blinded, randomised controlled trial. Lancet Neurol 2019;18:821-33.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/21/01) and the Tavistock Trust for Aphasia.To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000864/after-a-stroke-computerised-speech-and-language-therapy-can-help-people-find-words.


Assuntos
Afasia , Acidente Vascular Cerebral , Atenção , Humanos , Terapia da Linguagem , Fala
6.
BMJ ; 368: m453, 2020 Feb 26.
Artigo em Inglês | MEDLINE | ID: mdl-32102784

RESUMO

The studyCleland LC, McComb L, Kee F, et al. Effects of 20 mph interventions on a range of public health outcomes: a meta-narrative evidence synthesis. J Transp Health 2019. doi:10.1016/j.jth.2019.100633This project was funded by the NIHR Policy Research Programme (project number 17/149/19).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000853/twenty-mph-speed-zones-reduce-the-danger-to-pedestrians-and-cyclists.


Assuntos
Acidentes de Trânsito/prevenção & controle , Condução de Veículo/legislação & jurisprudência , Ciclismo/lesões , Pedestres , Ferimentos e Lesões/prevenção & controle , Ciclismo/legislação & jurisprudência , Humanos , Reino Unido
7.
BMJ ; 368: l6775, 2020 01 31.
Artigo em Inglês | MEDLINE | ID: mdl-32005673

RESUMO

The studyDambha-Miller H, Day AJ, Strelitz J, et al. Behaviour change, weight loss and remission of Type 2 diabetes: a community-based prospective cohort study. Diabet Med 2019. doi:10.1111/dme.14122This project was funded by the NIHR Health Technology Assessment Programme (project number 08/116/300) as well as the Wellcome Trust (grant number: G061895), the Epidemiology Unit programme (MC_UU_12015/4), and the National Health Service R&D support funding.To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000841/weight-loss-after-type-2-diabetes-diagnosis-boosts-chance-of-remission.


Assuntos
Diabetes Mellitus Tipo 2 , Perda de Peso , Peso Corporal , Humanos , Estudos Prospectivos , Medicina Estatal
8.
BMJ ; 368: l6779, 2020 01 15.
Artigo em Inglês | MEDLINE | ID: mdl-31941696

RESUMO

The studyChappell LC, Brocklehurst P, Green ME, et al. Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial. Lancet 2019;394:1181-90.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/25/03).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000838/mothers-benefit-from-a-planned-earlier-delivery-for-late-pre-eclampsia.


Assuntos
Pré-Eclâmpsia , Nascimento Prematuro , Feminino , Humanos , Recém-Nascido , Mães , Gravidez , Avaliação da Tecnologia Biomédica , Conduta Expectante
9.
BMJ ; 368: l6768, 2020 01 10.
Artigo em Inglês | MEDLINE | ID: mdl-31924664

RESUMO

The studyCabral C, Horwood J, Symonds J, et al. Understanding the influence of parent-clinician communication on antibiotic prescribing for children with respiratory tract infections in primary care: a qualitative observational study using a conversation analysis approach. BMC Fam Pract 2019;20:102.This project was funded by the NIHR School for Primary Care Research Programme (project number SPCR204).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000829/gps-assessment-not-parental-expectation-drives-antibiotic-prescribing.


Assuntos
Antibacterianos , Infecções Respiratórias , Criança , Humanos , Motivação , Pais , Atenção Primária à Saúde
10.
BMJ ; 368: l6764, 2020 01 03.
Artigo em Inglês | MEDLINE | ID: mdl-31900245

RESUMO

The studyCooper K, Breeman S, Scott NW, et al. Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial. Lancet 2019;394:1425-36.The study was funded by the NIHR Health Technology Assessment Programme (project number 12/35/23).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000837/keyhole-hysterectomy-is-effective-for-women-with-heavy-menstrual-bleeding.


Assuntos
Técnicas de Ablação Endometrial , Laparoscopia , Menorragia/cirurgia , Feminino , Humanos , Histerectomia , Avaliação da Tecnologia Biomédica
11.
BMJ ; 367: l4962, 2019 11 04.
Artigo em Inglês | MEDLINE | ID: mdl-31685480

RESUMO

The studyEveritt H, Landau G, Little P. Therapist telephone-delivered CBT and web-based CBT compared with treatment as usual in refractory irritable bowel syndrome: the ACTIB three-arm RCT. Health Technol Assess 2019;23:1-154.This project was funded by the NIHR Health Technology Assessment Programme (project number 11/69/02).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000784/irritable-bowel-syndrome-helped-by-telephone-or-internet-cbt.


Assuntos
Síndrome do Intestino Irritável , Humanos , Internet , Fonoterapia , Avaliação da Tecnologia Biomédica , Telefone
12.
BMJ ; 367: l4993, 2019 11 04.
Artigo em Inglês | MEDLINE | ID: mdl-31685481

RESUMO

The studyGilbert R, Brown M, Rainford N et al. Antimicrobial-impregnated central venous catheters for prevention of neonatal bloodstream infection (PREVAIL): an open-label, parallel-group, pragmatic, randomised controlled trial. Lancet Child Adolesc Health 2019;3:381-90.The study was funded by the NIHR Health Technology Assessment programme (project number 12/167/02).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000782/antimicrobial-central-venous-catheters-for-pre-term-babies-do-not-reduce-infections.


Assuntos
Anti-Infecciosos , Bacteriemia , Cateteres Venosos Centrais , Antibacterianos , Criança , Humanos , Lactente , Recém-Nascido , Avaliação da Tecnologia Biomédica
13.
BMJ ; 367: l5464, 2019 11 11.
Artigo em Inglês | MEDLINE | ID: mdl-31712247

RESUMO

The studyLyttle MD, Rainford NEA, Gamble C, et al. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet 2019;393:2125-34.This trial was funded by the NIHR Health Technology Assessment Programme (project number 12/127/134).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000790/levetiracetam-vs-phenytoin-in-stopping-childrens-prolonged-epileptic-seizures.


Assuntos
Epilepsia , Estado Epiléptico , Criança , Humanos , Levetiracetam , Fenitoína , Convulsões
14.
BMJ ; 367: l5721, 2019 11 08.
Artigo em Inglês | MEDLINE | ID: mdl-31704711

RESUMO

The studyCoomarasamy A, Devall AJ, Cheed V, et al. A randomised trial of progesterone in women with bleeding in early pregnancy N Engl J Med 2019;380:1815-24.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/167/26).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000792/miscarriage-not-prevented-by-routine-use-of-progesterone.


Assuntos
Aborto Espontâneo , Feminino , Humanos , Gravidez , Progesterona , Avaliação da Tecnologia Biomédica
15.
BMJ ; 367: l5462, 2019 10 09.
Artigo em Inglês | MEDLINE | ID: mdl-31597637

RESUMO

The studyPeden CJ, Stephens T, Martin G et al. Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial. Lancet 2019;393:2213-21.This project was funded by the NIHR Health Services and Delivery Research Programme (project number 12/5005/10).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000789/national-quality-improvement-programmes-need-time-and-resources-to-have-impact.


Assuntos
Dor Abdominal/cirurgia , Procedimentos Cirúrgicos do Sistema Digestório , Tratamento de Emergência , Melhoria de Qualidade/organização & administração , Doença Aguda , Análise por Conglomerados , Procedimentos Clínicos , Procedimentos Cirúrgicos do Sistema Digestório/normas , Tratamento de Emergência/normas , Humanos , Avaliação de Programas e Projetos de Saúde , Melhoria de Qualidade/normas
16.
BMJ ; 367: l5456, 2019 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-31575520

RESUMO

The studyTaylor RS, Walker S, Ciani O, et al. Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis. Health Technol Assess 2019;23:1-98.This project was funded by the NIHR Health Technology Assessment Programme (project number 15/80/30).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000803/cardiac-rehabilitation-for-heart-failure-can-improve-quality-of-life-and-fitness.


Assuntos
Reabilitação Cardíaca , Insuficiência Cardíaca , Exercício Físico , Terapia por Exercício , Humanos , Qualidade de Vida
17.
BMJ ; 366: l5453, 2019 09 27.
Artigo em Inglês | MEDLINE | ID: mdl-31562125

RESUMO

The studyTaylor S, Mallett S, Beare S et al. Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial. Lancet Gastroenterol Hepatol 2019;4:529-37.This project was funded by the NIHR Health Technology Assessment Programme (project number 10/68/01).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000797/identifying-metastatic-disease-in-colorectal-cancer-with-whole-body-mri.


Assuntos
Neoplasias Colorretais , Segunda Neoplasia Primária , Humanos , Imagem por Ressonância Magnética , Estudos Prospectivos , Avaliação da Tecnologia Biomédica
18.
BMJ ; 366: l4915, 2019 08 27.
Artigo em Inglês | MEDLINE | ID: mdl-31455630

RESUMO

The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funded by the NIHR Research for Patient Benefit Programme (project number PB-PG-1013-32069).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000785/antiretroviral-treatment-can-reduce-the-risk-of-hiv-transmission-between-male-partners-to-zero.


Assuntos
Infecções por HIV , Minorias Sexuais e de Gênero , HIV , Humanos , Masculino , Estudos Prospectivos , Parceiros Sexuais
19.
BMJ ; 366: l4920, 2019 08 29.
Artigo em Inglês | MEDLINE | ID: mdl-31466942

RESUMO

The studyStory A, Aldridge R, Smith C, et al. Smartphone-enabled video-observed versus directly observed treatment for tuberculosis: a multicentre, analyst-blinded, randomised, controlled superiority trial. Lancet 2019;393:1216-24.The study was funded by the NIHR Programme Grants for Applied Research programme (project number RP-PG-0407-10340).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000777/smartphones-for-tb-treatment-observation.


Assuntos
Smartphone , Tuberculose , Humanos
20.
BMJ ; 366: l4912, 2019 08 23.
Artigo em Inglês | MEDLINE | ID: mdl-31444168

RESUMO

The studyFeatherstone K, Northcott A, Harden J, et al. Refusal and resistance to care by people living with dementia being cared for within acute hospital wards: an ethnographic study. Health Serv Deliv Res 2019;7.This study was funded by the National Institute for Health Research Health Services and Delivery Research Programme (project number 13/10/80).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000779/understanding-dementia-care-in-hospitals.


Assuntos
Demência/enfermagem , Demência/psicologia , Hospitalização , Cooperação do Paciente , Inglaterra , Humanos , Relações Profissional-Paciente , Medicina Estatal/normas , País de Gales
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