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1.
Artigo em Inglês | MEDLINE | ID: mdl-32844351

RESUMO

In this work, the previously proposed Fibonacci-type photobioreactor is scaled up and evaluated to produce Dunaliella salina. First, the composition of the culture medium was optimized to achieve maximal productivity. Next, the Fibonacci-type reactor was scaled up to 1250 L maintaining high solar radiation interception capacity of this type of reactor. Finally, the performance of the reactor for the production of green cells of Dunaliella salina at the environmental conditions prevailing in the Atacama Desert was evaluated. Data demonstrated that the proposed photobioreactor allows the temperature, pH and dissolved oxygen concentration to be maintained within the optimal ranges recommended for the selected strain. Both better exposure to solar radiation and photonic flow dilution avoids the use of cooling systems to prevent overheating under outdoor conditions. The system allows up to 60% more solar radiation to be intercepted than does the horizontal surface, likewise, allowing to maintain the pH efficiently through CO2 injection and to keep the dissolved oxygen concentration in acceptable ranges, thanks to its adequate mass transfer capacity. The biomass concentration reached up to 0.96 g L-1, three times higher than that obtained in a raceway reactor under the same environmental conditions, whereas productivity was up to 0.12 g L-1 day (2.41 g m-2 day). Maximum specific outdoor growth rates reached up to 0.17 day-1. Undoubtedly, this technology scaled up constitutes a new type of photobioreactor for use at the industrial scale since it is capable of maximizing biomass productivity under high light conditions.

2.
Artigo em Espanhol | LILACS | ID: biblio-1120174

RESUMO

El siguiente trabajo tiene como objetivo general la descripción de los procesos neurobiológicos de la consolidación y reconsolidación de la memoria, mientras que el específico, pretende vincular ambos mecanismos con situaciones de enseñanza y de aprendizaje de educación formal. El presente aborda las teorías en torno a estos procesos desde una perspectiva sistémico-evolutiva. Esto es, entendidas como totalidades complejas jerárquicamente organizadas, en tanto procesos psicobiológicos y neurocognitivos complementarios subyacentes en la memoria y potenciación a largo plazo y propiedad emergente de la conducta. Se exponen investigaciones que pusieron en debate estos dos procesos neurocognitivos, y los últimos hallazgos en animales no humanos y humanos; aportaciones extrapoladas a situaciones y estrategias de enseñanza y aprendizaje. Finalmente, los dos planos epistemológicos: estructural-molecular (consolidación y reconsolidación de la memoria) y conductual (enseñanza y aprendizaje), se explicitan atento a puentes epistémicos que dan cuenta de la integración de la complejidad de ambos campos


Assuntos
Humanos , Adulto Jovem , Educação , Consolidação da Memória , Aprendizagem , Estratégias , Potenciação de Longa Duração
3.
Rev. Fac. Med. (Guatemala) ; 1(25 Segunda Época): 13-21, Jun - Dic 2018.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1122737

RESUMO

Introducción: Las faringitis producidas por el estreptococo beta hemolítico del grupo A no se pueden distinguir clínicamente de las faringitis producidas por otros gérmenes, sin embargo la utilización de los criterios de Centor y el test de detección rápida de antígeno son de gran utilidad para determinar las probabilidades que estos sean causados por el estreptococo beta hemolítico del grupo A. En este estudio se comparó la sensibilidad entre ambos métodos. Objetivos: Se realizó un estudio para determinar la sensibilidad del criterio clínico en el diagnóstico de faringitis causada por Estreptococo en comparación a la sensibilidad del test de detección rápida de antígeno. Metodología: En el Centro de Salud Bárbara, se tomaron a los pacientes pediátricos que consultaron por dolor de garganta durante dos meses. Se puntuó según la escala de Centor y se tomó una muestra para el test de detección rápida de antígeno, luego, se comparó con el cultivo de orofaringe. Resultados: Se comparó la sensibilidad de ambos parámetros. Discusión: Un puntaje ≥ 3 puntos en la escala de Centor tuvo una sensibilidad de 81.8% y especificidad de 50%. Mientras que el RADT presentó una sensibilidad del 83.3% y especificidad de 84.2%.


Introduction: Pharyngitis caused by group A beta-hemolytic streptococci cannot be distinguished clinically from pharyngitis caused by other germs, however the use of the Centor criteria and the rapid antigen detection test are very useful to determine this pathogen. These are likely to be caused by group A beta hemolytic streptococcus. In this study the sensitivity between the two methods were compared. Objectives: A study was conducted to determine the sensitivity of clinical criteria in the diagnosis of pharyngitis caused by Streptococcus in comparison to the sensitivity of the rapid antigen detection test. Methodology: In the Barbara Health Center, pediatric patients who consulted for sore throat for two months were taken. It was scored according to the Centor scale and a sample was taken for the rapid antigen detection test, later these were compared with the oropharynx culture. Results: The sensitivity of both parameters were compared. Discussion: A score ≥ 3 points on the Centor scale had a sensitivity of 81.8% and specificity of 50%. While the RADT presented a sensitivity of 83.3% and specificity of 84.2%.

4.
Vet Anim Sci ; 6: 64-68, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32734054

RESUMO

Different analytical tools were used to determine the seroprevalence of and risk factors associated with Leptospira spp infection in 192 domestic dogs (Canis familiaris) in Bogotá, Colombia. Using the microscopic agglutination test (MAT), a battery of 16 Leptospira serovars were tested. The seroprevalence of Leptospira spp was calculated as 36.46% (95% CI 0.30-0.43). A questionnaire was applied to the dogs' owners at the time of sampling and the variables "Water sources near home" and "Dog hunting rodents" were identified as risk factors for leptospirosis occurrence in the urban area of Bogotá. Geographical coordinates relating to the dogs' households were obtained in order to map out the spatial distribution of reactive and unreactive dogs. Additionally, we found that the mean annual precipitation was higher at geographical locations with reactive animals than at those with unreactive dogs (p < 0.05). Preventing exposure of dogs to rodents and waste-water bodies that could be contaminated with Leptospira might effectively reduce occurrences of leptospirosis. Moreover, promoting preventive programs and vaccination of dogs against leptospirosis in areas of higher precipitation and prior to rainy months could be an effective strategy for leptospirosis prevention.

5.
Rev. med. interna ; 17(Suppl 1): s30-s34, nov. 2013. graf
Artigo em Espanhol | LILACS | ID: biblio-836240

RESUMO

La Diabetes Mellitus es una enfermedad crónica metabólica. El aumento que se ha dado en la cantidad de personas afectadas por Diabetes Mellitus es exponencial. Específicamente para Centro y Suramérica, para 2010 se estimaron aproximadamente 18 millones de personas afectadas. Actualmente 52% del total de las personas diabéticas en el continente viven en América Latina. La Diabetes Mellitus incrementa el riesgo de muerte prematura debido principalmente a un aumento en el riesgo de enfermedades cardiovasculares. La obesidad se presenta como el principal factor relacionado con este aumento en la prevalencia de Diabetes a nivel mundial.


Diabetes Mellitus is a chronic metabolic disease. The increase has occurred in the number of people affectedby Diabetes Mellitus is exponential. Specifically, Central and South America by 2010 about 18 million peopleaffected were estimated. Currently 52% of all diabetics in our continent, live in Latin America. Diabetesmellitus increases the risk of premature death due mainly to an increased risk of cardiovascular disease.Obesity is reported as the principal factor involved in this increase in the prevalence of the Diabetesworldwide.


Assuntos
Humanos , Diabetes Mellitus/epidemiologia , Doença Crônica/epidemiologia , Obesidade/complicações , Qualidade de Vida , Fatores Socioeconômicos
6.
Endocr Pract ; 15(1): 41-6, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19211396

RESUMO

OBJECTIVE: To evaluate the psychosocial barriers to insulin use in low-income, type 2 diabetic patients; the clinical characteristics of these patients; and the possible causes of nonadherence to insulin regimens months after prescription. METHODS: We studied a prospective cohort of low-income patients with type 2 diabetes mellitus, aged 45 to 75 years, attending a tertiary health care center in Mexico City, Mexico. Patients were eligible if their diabetes was not controlled with oral agents, and they were excluded if they had type 1 diabetes mellitus, a secondary cause of diabetes, had been admitted to the hospital within the month before study commencement, had been previously treated with insulin, had severe diabetic complications, or had a chronic or disabling medical illness. All patients were prescribed 6 to 10 units of neutral protamine Hagedorn insulin before bedtime and received a referral to visit with a diabetes nurse educator. The main outcome was adherence or nonadherence to insulin therapy, and it was correlated with several variables including attitudes toward insulin, diabetes self-management, diabetes-related knowledge, depression, and diabetes-related distress. Brief medical history, complete battery of questionnaires, and laboratory workup were obtained at baseline and 1 to 3 months after insulin prescription. RESULTS: Twenty-nine consecutive patients were included. Mean age (+/- standard deviation) was 59 +/- 8 years, 18 (62%) were women, mean diabetes duration was 14 +/- 9 years, and mean hemoglobin A1c level was 10.8 +/- 1.4%. Negative attitudes toward insulin were very common, particularly in patients with less education and poorer diabetes-related knowledge (odds ratio, 6.2; 95% confidence interval, 1.04-47.3; P = .02). Even when they received precise recommendations, 12 patients (41%) did not adhere to insulin treatment. Patients who did not adhere to therapy were most commonly women and were depressed (P = .05). Improved adherence was significantly associated with the additional support of a diabetes nurse educator (odds ratio, 6.6; 95% confidence interval, 1.0-55.7; P = .02). CONCLUSIONS: Improving patient perception and acceptance of insulin with the help of diabetes educators can facilitate earlier and more aggressive intervention and thus optimize glycemic control.


Assuntos
Diabetes Mellitus Tipo 2/tratamento farmacológico , Diabetes Mellitus Tipo 2/psicologia , Hipoglicemiantes/uso terapêutico , Insulina/uso terapêutico , Adesão à Medicação/psicologia , Cooperação do Paciente/psicologia , Pobreza/psicologia , Idoso , Atitude Frente a Saúde , Estudos de Coortes , Depressão/psicologia , Diabetes Mellitus Tipo 2/sangue , Feminino , Hemoglobina A Glicada/metabolismo , Humanos , Masculino , Adesão à Medicação/etnologia , México , Pessoa de Meia-Idade , Cooperação do Paciente/etnologia , Pobreza/etnologia , Estudos Prospectivos , Estudos Retrospectivos , Autoimagem , Apoio Social , Inquéritos e Questionários
7.
Rev. med. interna ; 12(2): 49-50, dic. 2001. tab
Artigo em Espanhol | LILACS | ID: lil-343291

RESUMO

La tuberculosis es una causa importante de morbilidad en nuestro país, debido a que ha aumentado su incidencia con el advenimiento de la epidemia del virus de inmunodeficiencia adquirida. En el presente trabajo se determinó la incidencia de tuberculosis en sus diferentes formas en el departamento de Medicina Interna del Hospital Roosevelt en el período comprendido de mayo de 1999 a mayo del 2001. También se determinó la distribución de los pacientes en cuanto a sexo, edad, procedencia, COMBE, tipo de tuberculosis, presencia de enfermedades concomitantes, asociación con infección por Virus de Inmunodeficiencia Humana, así como el tipo de patrones radiológicos encontrados, tipo de tratamiento recibido y seguimiento de los pacientes. El estudio es de tipo descriptivo y se realizó en la población indicada, recolectando los datos en una boleta elaborada para tal efecto. Se determinó que la tuberculosis se presenta de forma similar en uno y otro sexo, con un ligero predominio del sexo masculino con 52 por ciento de los casos. El grupo etáreo más afectado fue el de 14 a 44 años con 70.1 por ciento de los casos. El tipo de tuberculosis más frecuente fue la tuberculosis pulmonar con 52.4 por ciento, seguida por la tuberculosis miliar con 17.9 por ciento. La mayoría de pacientes procedían del departamento de Guatemala con 52 por ciento de los casos. La enfermedad asociada más frecuente fue el Síndrome de Inmunodeficiencia Adquirida con 47 por ciento de los casos. Los patrones radiológicos pulmonares fueron el alveolar y el miliar (17 por ciento y 16 por ciento respectivamente). La mayoría de pacientes (84 por ciento) recibió esquema de cuatro medicamentos antitu-berculosos pero 70 por ciento no tuvo ningún tipo de seguimiento, luego de su egreso. Se determinó que la incidencia de tuberculosis fue de 29.76 casos por mil, al tomar en cuenta el número de cultivos positivos en el período estudiado, pero de 10.36 casos por mil si se toman sólo a los pacientes que ingresaron al estudio


Assuntos
Humanos , Masculino , Adolescente , Adulto , Feminino , Síndrome de Imunodeficiência Adquirida , Tuberculose , Tuberculose Miliar , Tuberculose Pulmonar
8.
Pediatr. día ; 15(3): 146-8, jul.-ago. 1999.
Artigo em Espanhol | LILACS | ID: lil-255256

RESUMO

Comunicamos el caso de una preescolar que ingresa a nuestra unidad de cuidados intensivos, con crisis bronquial obstructiva grave e insuficiente respiratoria global que no responde al tratamiento convencional, y en el que se utiliza con éxito ketamina en infusión ev continua. Se han descrito mortalidades tan altas como 35 por ciento, en pacientes clínicamente similares manejados con ventilación mecánica, por lo que nos ha parecido importante describir la evolución y el tratamiento de esta paciente. No encontramos en la revisión de la literatura nacional otras comunicaciones relacionadas


Assuntos
Humanos , Feminino , Pré-Escolar , Estado Asmático/tratamento farmacológico , Ketamina/administração & dosagem , Insuficiência Respiratória/tratamento farmacológico , Infusões Intravenosas , Respiração Artificial
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