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1.
Arq Bras Cardiol ; 105(2 Suppl 1): 1-105, 2015 Aug.
Artigo em Português | MEDLINE | ID: mdl-26375058
2.
Rev. bras. cardiol. invasiva ; 17(2): 220-226, abr.-jun. 2009. ilus, tab, graf
Artigo em Português | LILACS | ID: lil-527896

RESUMO

A medicina regenerativa tem ganho grande importância nos últimos anos em decorrência da possibilidade de certas células se diferenciarem em linhagens celulares distintas e, assim, recontruírem o tecido lesado. As células-tronco têm despontado como forma alternativa de tratamento para doenças pela sua capacidade de diferenciação nos mais de 100 tipos de tecido. A medula óssea contém células-tronco adultas, hematopoéticas e mesenquimais, que auxiliam na limitação do remodelamento cardíaco...


Assuntos
Animais , Cães , Cães/cirurgia , Células-Tronco , Cateterismo Cardíaco/métodos
3.
Arq Bras Cardiol ; 81(2): 174-81, 166-73, 2003 Aug.
Artigo em Inglês, Português | MEDLINE | ID: mdl-14502386

RESUMO

OBJECTIVE: To assess safety, feasibility, and the results of early exercise testing in patients with chest pain admitted to the emergency room of the chest pain unit, in whom acute myocardial infarction and high-risk unstable angina had been ruled out. METHODS: A study including 1060 consecutive patients with chest pain admitted to the emergency room of the chest pain unit was carried out. Of them, 677 (64%) patients were eligible for exercise testing, but only 268 (40%) underwent the test. RESULTS: The mean age of the patients studied was 51.7 12.1 years, and 188 (70%) were males. Twenty-eight (10%) patients had a previous history of coronary artery disease, 244 (91%) had a normal or unspecific electrocardiogram, and 150 (56%) underwent exercise testing within a 12-hour interval. The results of the exercise test in the latter group were as follows: 34 (13%) were positive, 191 (71%) were negative, and 43 (16%) were inconclusive. In the group of patients with a positive exercise test, 21 (62%) underwent coronary angiography, 11 underwent angioplasty, and 2 underwent myocardial revascularization. In a univariate analysis, type A/B chest pain (definitely/probably anginal) (p<0.0001), previous coronary artery disease (p<0.0001), and route 2 (patients at higher risk) correlated with a positive or inconclusive test (p<0.0001). CONCLUSION: In patients with chest pain and in whom acute myocardial infarction and high-risk unstable angina had been ruled out, the exercise test proved to be feasible, safe, and well tolerated.


Assuntos
Dor no Peito/fisiopatologia , Serviço Hospitalar de Emergência , Teste de Esforço , Idoso , Análise de Variância , Estudos de Coortes , Teste de Esforço/efeitos adversos , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Segurança , Resultado do Tratamento
4.
Arq. bras. cardiol ; 81(2): 166-181, ago. 2003. ilus, tab
Artigo em Português, Inglês | LILACS | ID: lil-345307

RESUMO

OBJECTIVE: To assess safety, feasibility, and the results of early exercise testing in patients with chest pain admitted to the emergency room of the chest pain unit, in whom acute myocardial infarction and high-risk unstable angina had been ruled out. METHODS: A study including 1060 consecutive patients with chest pain admitted to the emergency room of the chest pain unit was carried out. Of them, 677 (64 percent) patients were eligible for exercise testing, but only 268 (40 percent) underwent the test. RESULTS: The mean age of the patients studied was 51.7±12.1 years, and 188 (70 percent) were males. Twenty-eight (10 percent) patients had a previous history of coronary artery disease, 244 (91 percent) had a normal or unspecific electrocardiogram, and 150 (56 percent) underwent exercise testing within a 12-hour interval. The results of the exercise test in the latter group were as follows: 34 (13 percent) were positive, 191 (71 percent) were negative, and 43 (16 percent) were inconclusive. In the group of patients with a positive exercise test, 21 (62 percent) underwent coronary angiography, 11 underwent angioplasty, and 2 underwent myocardial revascularization. In a univariate analysis, type A/B chest pain (definitely/probably anginal) (p<0.0001), previous coronary artery disease (p<0.0001), and route 2 (patients at higher risk) correlated with a positive or inconclusive test (p<0.0001). CONCLUSION: In patients with chest pain and in whom acute myocardial infarction and high-risk unstable angina had been ruled out, the exercise test proved to be feasible, safe, and well tolerated


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Dor no Peito , Serviço Hospitalar de Emergência , Teste de Esforço , Estudos de Coortes , Segurança de Equipamentos , Estudos de Viabilidade , Estudos Prospectivos , Resultado do Tratamento
5.
Tex Heart Inst J ; 30(1): 19-26, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-12638666

RESUMO

We performed this prospective cohort study to correlate the findings of left ventricular angiography (LVA) and NOGA left ventricular electromechanical mapping (LVEM) in the evaluation of cardiac wall motion and also to establish standards for wall motion assessment by LVEM. Fifty-five patients (35 men; mean age, 60.4 +/- 11.8 years) eligible for elective left cardiac catheterization underwent LVA and LVEM. Wall motion scores, LV ejection fractions (LVEF), and LV volumes derived from LVA versus LVEM data were compared and analyzed statistically. Receiver operating characteristic (ROC) curves were used to assess the accuracy of LVEM in distinguishing between normal, hypokinetic, and akinetic/dyskinetic wall motion. Mean LVEM procedure time was 37 +/- 11 minutes. The LVEM and LVA findings differed for mean LVEF (55% +/- 13% vs 36% +/- 9%), mean end-systolic volume (56 +/- 13 mL vs 36 +/- 10 mL), and mean end-diastolic volume (174 +/- 104 mL vs 123 +/- 65 mL). Mean wall motion scores (+/- SD) for normokinetic, hypokinetic, and akinetic/dyskinetic segments were 13.9% +/- 5.6%, 8.3% +/- 5.2%, and 3.2% +/- 3.1%, respectively. Cutpoints for differentiating between wall motion types were 12% and 6%. The ROC curves showed LVEM to have a 93% accuracy in differentiating between normokinetic and akinetic/dyskinetic segments and a 73% accuracy between normokinetic and hypokinetic segments. These data suggest that LVEM can differentiate between normal and abnormal cardiac wall motion, although it is more accurate at differentiating between normokinetic and akinetic/dyskinetic motion than between normokinetic and hypokinetic motion.


Assuntos
Angiografia Coronária , Eletromiografia/métodos , Eletromiografia/normas , Guias de Prática Clínica como Assunto/normas , Software/normas , Disfunção Ventricular Esquerda/diagnóstico por imagem , Disfunção Ventricular Esquerda/fisiopatologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Estudos de Coortes , Eletromiografia/instrumentação , Feminino , Humanos , Imagem Tridimensional/instrumentação , Imagem Tridimensional/métodos , Imagem Tridimensional/normas , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Disfunção Ventricular Esquerda/diagnóstico
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