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1.
Rev. Soc. Esp. Dolor ; 27(4): 269-272, jul.-ago. 2020. ilus
Artigo em Espanhol | IBECS | ID: ibc-196843

RESUMO

Las fracturas costales tienen una elevada prevalencia en nuestra sociedad. Un adecuado y precoz control analgésico resulta fundamental a la hora de evitar complicaciones respiratorias y favorecer una rápida recuperación funcional en los pacientes con fracturas costales. Se han empleado diferentes estrategias para dicho control analgésico, desde fármacos intravenosos hasta técnicas regionales más clásicas como el catéter epidural o el bloqueo paravertebral torácico. El bloqueo ecoguiado del plano profundo del músculo erector de la espina (ESPB) constituye una alternativa eficaz en el manejo del dolor agudo derivado de las fracturas costales, permitiendo una fisioterapia y rehabilitación precoz


Rib fractures have a high prevalence in our society. An adequate and precocious analgesic control is essential to avoid respiratory complications and favor a rapid functional recovery in patients with rib fractures. Different strategies have been used for analgesic control, from intravenous drugs to more classic regional techniques such as epidural catheter or thoracic paravertebral block. Ultrasound-guided blockade of the deep plane of the erector spine muscle (ESPB) is an effective alternative in the management of acute pain derived from rib fractures, allowing physiotherapy and early rehabilitation


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/complicações , Dor Aguda/tratamento farmacológico , Fraturas das Costelas/tratamento farmacológico , Analgésicos/administração & dosagem , Analgesia Controlada pelo Paciente/métodos , Bloqueio Nervoso/métodos , Infusão Espinal/métodos , Resultado do Tratamento , Medição da Dor/métodos , Cateteres de Demora , Cateterismo/métodos
2.
Data Brief ; 30: 105537, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32346571

RESUMO

This data article presents data on the results in national assessments for secondary and university education in engineering students. The data contains academic, social, economic information for 12,411 students. The data were obtained by orderly crossing the databases of the Colombian Institute for the Evaluation of Education (ICFES). The structure of the data allows us to observe the influence of social variables and the evolution of students' learning skills. In addition to serving as input to develop analysis of academic efficiency, student recommendation systems and educational data mining. The data is presented in comma separated value format. Data can be easily accessed through the Mendeley Data Repository (https://data.mendeley.com/datasets/83tcx8psxv/1).

3.
Artigo em Inglês | MEDLINE | ID: mdl-31233887

RESUMO

Endoplasmic reticulum (ER)-associated protein degradation (ERAD) is a conserved cellular process that apart from protein quality control and maintenance of ER membrane identity has pivotal functions in regulating the lipid composition of the ER membrane. A general trigger for ERAD activation is the exposure of normally buried protein domains due to protein misfolding, absence of binding partners or conformational changes. Several feedback loops for ER lipid homeostasis exploit the induction of conformational changes in key enzymes of lipid biosynthesis or in ER membrane-embedded transcription factors upon shortage or abundance of specific lipids, leading to enzyme degradation or mobilization of transcription factors. Similarly, an insufficient amount of lipids triggers ERAD of apolipoproteins during lipoprotein formation. Lipids might even have a role in ER protein quality control: when proteins destined for ER export are covalently modified with lipids their ER residence time and their susceptibility to ERAD is reduced. Here we summarize and compare the various interconnections of lipids with ER membrane proteins and ERAD. This article is part of a Special Issue entitled Endoplasmic reticulum platforms for lipid dynamics edited by Shamshad Cockcroft and Christopher Stefan.


Assuntos
Degradação Associada com o Retículo Endoplasmático , Metabolismo dos Lipídeos , Animais , Retículo Endoplasmático/metabolismo , Humanos , Lipoproteínas/metabolismo , Proteínas de Membrana/metabolismo , Esteróis/metabolismo , Fatores de Transcrição/metabolismo
4.
Rev. cuba. salud pública ; 45(3): e1458, jul.-sep. 2019. tab
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1058434

RESUMO

RESUMEN Introducción: La cobertura de los programas de vacunación infantil está asociada con la probabilidad de supervivencia de los infantes y es una medida de desempeño de los sistemas nacionales de inmunización. Objetivo: Caracterizar los programas de vacunación infantil en países latinoamericanos a partir de la supervivencia de infantes durante el periodo 2000-2015. Método: Se realizó un estudio descriptivo retrospectivo del programa de inmunización de 21 países de América Latina soportado en la metodología del análisis envolvente de datos con ventanas de tiempo. Las variables asociadas son: vacunas (Bacillus calmette-Guérin, difteria, Bordetella pertussis y el tétanos, sarampión, polio) y tasa de supervivencia (menores de 1 año, menores de 5 años). Resultado: Durante el periodo de estudio, 2000-2015, la eficiencia de los programas de vacunación varió entre el 77 % y el 99 % y la ineficiencia se comportó entre el rango de valores del 1 % al 23 %. Se pudieron identificar cuatro grupos de países con una clasificación correcta del 95,2 %. Conclusiones: En América Latina los programas de vacunación infantil tienen comportamientos diferentes en cada país. El conjunto formado por Argentina, Brasil, Cuba, México y Uruguay son referentes en este tipo de programa, debido a la tasa de cobertura de vacunación y tasa de supervivencia de niños menores a cinco años de edad, de acuerdo a los resultados de eficiencia, este grupo podría obtener iguales tasas de supervivencia con menor tasa de cobertura.


ABSTRACT Introduction: Coverage of children vaccination programs is associated with the survival probability of infants and it is a measure of the performance of national immunization systems. Objective: To characterize children vaccination programs in Latin American countries from infants survival during 2000-2015. Methods: A retrospective descriptive study of the immunization program in 21 Latin American countries was carried out based in the methodology of the data envelopment analysis with time windows. The associated variables were: vaccines (Bacillus Calmette-Guérin, diphtheria, Bordetella pertussis and tetanus, measles, polio) and survival rate (under 1 year, under 5 years). The information was taken from the reports of the World Health Organization. Results: During the studied period (2000-2015), the efficiency of vaccination programs varied between 77 % and 99 %, and the inefficiency was in the range from 1 % to 23 %. The result showed the identification of four groups of countries with a correct classification of 95,2 %. Conclusions: In Latin America, children's vaccination programs present different behaviors in each country. The group formed by Argentina, Brazil, Cuba, Mexico and Uruguay are the reference in children vaccination programs, due to the rate of vaccination coverage and the survival rates in children under 5 years. In accordance to the efficiency results, this group would have equal survival rates with less rate of coverage.

5.
Annu Int Conf IEEE Eng Med Biol Soc ; 2019: 1002-1005, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31946062

RESUMO

Image segmentation is a common goal in many medical applications, as its use can improve diagnostic capability and outcome prediction. In order to assess the wound healing rate in diabetic foot ulcers, some parameters from the wound area are measured. However, heterogeneity of diabetic skin lesions and the noise present in images captured by digital cameras make wound extraction a difficult task. In this work, a Deep Learning based method for accurate segmentation of wound regions is proposed. In the proposed method, input images are first processed to remove artifacts and then fed into a Convolutional Neural Network (CNN), producing a probability map. Finally, the probability maps are processed to extract the wound region. We also address the problem of removing some false positives. Experiments show that our method can achieve high performance in terms of segmentation accuracy and Dice index.


Assuntos
Complicações do Diabetes , Diabetes Mellitus , Dermatopatias , Artefatos , Humanos , Processamento de Imagem Assistida por Computador , Redes Neurais de Computação
6.
Entramado ; 14(1): 78-87, ene.-jun. 2018. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1090163

RESUMO

ABSTRACT The present research is about the analysis financial efficiency of Colombian companies based on the city of Cali certified by the BASC label, for this purpose we used the linear programming technique called Data Envelopment Analysis (DEA), applying the CCR-O routine aimed to outputs. As input variables, it was worked with: Subtotal of inventory Total Current Assets, Plant and Equipment property and Suppliers, and as output variable, Operating Income. The quality of this work is based on the use of primary information collected by the Superintendence of Corporations in 2014. As results we find that average efficiency of 42 companies under study was 33.95%, besides only five companies reached highest efficiency levels. JEL CLASSIFICATION L69


RESUMEN La presente investigación desarrolla un análisis de eficiencia de empresas colombianas localizadas en la ciudad de Cali, certificadas en el sello BASC. Para este propósito se utilizó la técnica de programación lineal llamada Análisis Envolvente de Datos (DEA), aplicando la metodología CCR-O enfocada a las salidas. Como variables de entradas, se trabajó con: Sub-inventario total, Activos totales actuales, plantas propiedades, equipos y proveedores. Como variable de salida se utilizó el ingreso operativo. La calidad de este trabajo está dada por el uso de información primaria recolectada por la Superintendencia de Sociedades en 2014. Como resultados se encontró que la eficiencia promedio de las 42 empresas en estudio fue del 33.95%, además solo cinco empresas alcanzaron altos niveles de eficiencia. CÓDIGOS JEL L69


RESUMO Esta pesquisa desenvolve uma análise de eficiência de empresas colombianas localizadas na cidade de Cali, certificadas no selo BASC. Para tanto, utilizou-se a técnica de programação linear denominada Data Envelopment Analysis (DEA), aplicando a metodologia CCR-O focada nas saídas. Como variáveis de entrada, trabalhamos com: Sub-estoque total, Ativo total atual, propriedades da planta, equipamentos e fornecedores. Como variável de saída, foi utilizado o lucro operacional. A qualidade deste trabalho é dada pelo uso de informações primárias coletadas pela Superintendência de Empresas em 2014. Como resultado, verificou-se que a eficiência média das 42 empresas pesquisadas foi de 33,95%, e apenas cinco empresas atingiram altos níveis de eficiência. CLASSIFICAÇÕES JEL L69

7.
Int J Neural Syst ; 28(5): 1750056, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29297263

RESUMO

One of the most important challenges in computer vision applications is the background modeling, especially when the background is dynamic and the input distribution might not be stationary, i.e. the distribution of the input data could change with time (e.g. changing illuminations, waving trees, water, etc.). In this work, an unsupervised learning neural network is proposed which is able to cope with progressive changes in the input distribution. It is based on a dual learning mechanism which manages the changes of the input distribution separately from the cluster detection. The proposal is adequate for scenes where the background varies slowly. The performance of the method is tested against several state-of-the-art foreground detectors both quantitatively and qualitatively, with favorable results.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Redes Neurais de Computação , Humanos , Reconhecimento Automatizado de Padrão/métodos , Aprendizado de Máquina não Supervisionado
8.
rev. udca actual. divulg. cient ; 20(2): 469-478, jul.-dic. 2017. ilus, tab
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1094695

RESUMO

En este artículo de investigación, se analizó el comportamiento de lectores de un periódico digital, con el objetivo de encontrar los perfiles asociados al uso del sitio Web, con el propósito de definir estrategias de contenidos y nuevos productos del periódico. Se tomó una muestra de 689 usuarios, correspondiente a tres meses de actividad, a través de la herramienta Google Analytics; se determinaron las secciones del diario que se utilizaban en cada visita por los usuarios, para consolidar así la base de datos. En el proceso de análisis, se utilizaron las técnicas multivariadas, análisis de componentes principales y análisis de clúster, por medio, de la cual, se lograron gráficos y visualizaciones, que permiten una mejor interpretación de los resultados y ayudan al proceso de creación de perfiles de usuario. El resultado muestra la identificación de tres perfiles de usuario, para los cuales, se han definido estrategias de contenidos y de nuevos productos.


In this article, we analyzed the behavior of readers of a digital newspaper in order to find the profiles associated with the use of the website, in order to define content strategies and new newspaper products. A sample of 689 users was taken corresponding to three months of activity, through the tool Google Analytics, it was determined the sections of the newspaper that were used in each visit by the users to consolidate the database. In the process of analysis, the multivariate techniques are used main component analysis and cluster analysis, by means of which graphs and visualizations were obtained that allow a better interpretation of the results and help to the process of creation of user profiles. The result shows the identification of three user profiles, for which content strategies and new products have been defined.

9.
Rev. urug. cardiol ; 31(3): 390-397, dic. 2016. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-845925

RESUMO

Antecedentes: el ecocardiograma de estrés (ES) es una herramienta bien establecida para el diagnóstico y la estratificación de riesgo de la enfermedad coronaria. Este método permite identificar las situaciones de alto riesgo que requieren intervenciones, así como las de bajo riesgo que no las necesitan. Objetivo: establecer el valor pronóstico en nuestro medio del ES con fármacos en pacientes con enfermedad coronaria conocida o sospechada para predecir eventos cardíacos adversos mayores. Material y método: se evaluó en forma retrospectiva un grupo de 344 pacientes menores de 81 años sometidos a ES con fármacos para detección de isquemia miocárdica en forma consecutiva durante el período comprendido entre enero de 2011 y diciembre de 2012. Se realizó un seguimiento promedio de 3,4 ± 0,6 años mediante historia clínica electrónica y entrevista telefónica para consignar la ocurrencia de eventos cardíacos mayores incluyendo muerte de causa cardiovascular (CV), infarto agudo de miocardio (IAM) o necesidad de revascularización mediante angioplastia transluminal coronaria (ATC) o cirugía de revascularización miocárdica (CRM). Las variables cualitativas se analizaron mediante test exacto de Fisher y las cuantitativas mediante test t de Student o Mann-Whitney, según correspondiera. Se valoró la sobrevida libre de eventos mediante curvas de Kaplan Meier. Resultados: se completó el seguimiento en 300 pacientes, con una media de edad de 65 ± 10 años, 163 (54%) de sexo femenino y 137 (46%) de sexo masculino. Se presentaron eventos cardíacos mayores en 31 (10%), 3 con IAM, 28 con necesidad de revascularización y ninguna muerte de causa CV. Fueron positivos para isquemia 44 (14,7%) estudios y negativos 256 (85,3%). Los pacientes de sexo masculino tuvieron más del doble de riesgo de presentar resultado positivo (p=0,0050, OR 2,649, IC95% 1,354 a 5,183). La frecuencia de eventos cardiovasculares adversos fue mayor en aquellos que tenían ES positivo (29,5%) respecto a los negativos (7,0%), p<0,0001. La sensibilidad para predecir eventos fue de 41,9%, con una especificidad de 88,5%. Se encontró un valor predictivo positivo (VPP) de 29,5%, mientras que el valor predictivo negativo (VPN) fue de 93,0%. Conclusión: el ES con fármacos resultó una herramienta efectiva para la predicción de eventos cardíacos adversos mayores a largo plazo. El alto VPN permite definir un grupo de pacientes de bajo riesgo para eventos cardiovasculares mayores.


Assuntos
Humanos , Doença das Coronárias , Ecocardiografia sob Estresse
10.
Rev. guatem. cardiol. (Impresa) ; 24(1): 6-11, ene.-jun. 2014. tab
Artigo em Espanhol | LILACS | ID: biblio-869903

RESUMO

Introducción y objetivos: La válvula aórtica bicúspide (VAB) esta vinculada con la patología aórtica.Pacientes con VAB tienen elevada probabilidad de requerir cirugía debido a dilatación aórtica o afectaciónvalvular. La progresión en la dilatación aortica luego de la sustitución de la válvula aórtica (SVA), no se haevaluado forma definitoria. Métodos: Un total de 23 pacientes con VAB y diámetro de la raíz aortica inferior a45 mm fueron seguidos durante una media de 8 años luego de la SVA. La medición ecocardiográfica de laraíz aórtica y la aorta tubular se realizó a los 6 y 8 años de la cirugía. Se determinaron predictores dedilatación. Resultados: La raíz aórtica entre 6 (34,6 ± 7,4 mm) y 8 años (37,6 ± 7,7 mm) de seguimientoincrementó significativamente (p <0,023), no se encontraron diferencias con la aorta tubular. La dilatación seobservó principalmente entre fumadores, con antecedentes familiares y dislipémia. Los factores predictorespara dilatación de la raíz aórtica fueron: antecedentes familiares de VAB o patología aórtica, tamaño de laprótesis y superficie corporal (SC). El análisis de regresión multivariado evidenció solo la SC y antecedentesfamiliares como predictores significativos. Conclusión: La raíz aórtica continúa dilatándose tras la SVA enpacientes con VAB. La SC y la historia familiar de patología aórtica, son fuertes predictores de dilatación de laraíz aórtica. Estos pacientes deben ser seguidos de cerca luego de la SVA.


Background: Bicuspid aortic valve (BAV) has been closely correlated with aortic pathology. BAV patientshave a high probability of being operated along their lifetime for aortic disease. Progression of aortic dilatationafter aortic valve replacement (AVR) has not being definitely assessed. Methods: A total of 23 BAV withaortic diameter ≤ 45mm patients were followed for a mean of 8 years after AVR. Echocardiographicmeasurement of the aortic root and tubular aorta was done after a mean of 6 and 8 years post-operatively.Predictors for dilatation were estimated. Results: Paired comparison of aortic root diameter between 6(34.6±7.4 mm) and 8 years (37.6±7.7 mm) of follow-up showed that its dimension increased significantly(p<0.023) while no differences were found with the tubular aorta. Dilatation was seen mainly in smokers,family history and dyslipemic patients. Univariate predictors for aortic root dilatation were: family history ofBAV or aortic pathology, prosthesis size and body surface area (BSA). Multivariate regression evidenced onlyBSA (beta coefficient 11.5) and family history (beta coefficient 4.5) as significant predictors. Conclusion:Aortic root continues to dilate after AVR in BAV patients. Higher BSA and family history of aortic pathologywere found as strong predictors of aortic root dilatation. These patients should be closely followed after AVR.


Assuntos
Humanos , Cardiopatias Congênitas/complicações , Valva Aórtica/transplante , Valva Mitral/fisiologia
11.
Int J Neural Syst ; 24(4): 1450016, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24694171

RESUMO

Growing hierarchical self-organizing models are characterized by the flexibility of their structure, which can easily accommodate for complex input datasets. However, most proposals use the Euclidean distance as the only error measure. Here we propose a way to introduce Bregman divergences in these models, which is based on stochastic approximation principles, so that more general distortion measures can be employed. A procedure is derived to compare the performance of networks using different divergences. Moreover, a probabilistic interpretation of the model is provided, which enables its use as a Bayesian classifier. Experimental results are presented for classification and data visualization applications, which show the advantages of these divergences with respect to the classical Euclidean distance.


Assuntos
Inteligência Artificial , Modelos Neurológicos , Redes Neurais de Computação , Algoritmos , Humanos , Pesos e Medidas
12.
Rev. chil. cardiol ; 32(2): 104-110, 2013. ilus
Artigo em Espanhol | LILACS | ID: lil-688430

RESUMO

Introducción: La válvula aórtica bicúspide (VAB) está vinculada con la patología aórtica. Pacientes con VAB tienen elevada probabilidad de requerir cirugía debido a dilatación aórtica o afectación valvular. La progresión en la dilatación aortica luego de la sustitución de la válvula aórtica (SVA) no se ha evaluado en forma definitoria. Métodos: Un total de 23 pacientes con VAB y diámetro de la raíz aortica inferior a 45 mm fueron seguidos durante una media de 8 años luego de la SVA. La medición ecocardiográfica de la raíz aórtica y la aorta tubular se realizó a los 6 y 8 años de la cirugía. Se determinaron predictores de dilatación. Resultados: La raíz aórtica entre 6 y 8 años de seguimiento incrementó significativamente de 34,6 +/- 7,4 a 37,6 +/- 7,7 mm (p <0,023), mientras que no se encontraron diferencias con la aorta tubular. La dilatación se observa principalmente en los fumadores, aquellos con antecedentes familiares y en los pacientes dislipémicos. Los factores predictores para dilatación de la raíz aórtica fueron: antecedentes familiares de VAB o de patología aórtica, el tamaño de la prótesis y la superficie corporal (SC). El análisis de regresión multivariado evidenció solo la SC y antecedentes familiares como predictores significativos de dilatación. Conclusión: La raíz aórtica continúa dilatándose tras la SVA en pacientes con VAB. La SC y la historia familiar de patología aórtica son fuertes predictores de dilatación de la raíz aórtica. Estos pacientes deben ser seguidos de cerca luego de la SVA.


Background: The presence of a bicuspid aorotic valve (BAV) is associated to aortic disease. Along their lifetime, BAV patients are highly likely to require surgery. Progression of aortic dilatation after aortic valve replacement (AVR) has not been definitely assessed. Methods: A total of 23 BAV patients with aortic diameter < 45mm were followed for a mean of 8 years after AVR. The aortic root and proximal ascending aorta were measured by echocardiografy 6 and again 8 years after surgery. Predictors for dilatation were estimated based on demographic data and pharmacologic treatment. Results: The aortic root diameter increased from 34.6+/-7.4 to 37.6+/-7.7 mm at 6 and 8 years post surgery, respectively (p=0.023). No change was observed at the tubular aorta . Mean progression of aortic root and tubular aorta during the 2-year interval was 2.9+/-4.7 mm and 0.4+/-5.8 mm respectively. Dilatation was seen mainly in smokers, those with a family history or dyslipidemia. Univariate predictors for aortic root dilatation were: family history of BAV or aortic pathology, prosthesis size and body surface area (BSA). Multivariate regression evidenced only BSA (beta coefficient 11.5) and family history (beta coefficient 4.5) as significant predictors. Conclusion: Aortic root continues to dilate after AVR in BAV patients. Higher BSA and family history of aortic pathology were found to be strong predictors of aortic root dilatation. These patients should be closely followed after AVR.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Valva Aórtica/cirurgia , Valva Aórtica/fisiopatologia , Doenças da Aorta/cirurgia
13.
Molecules ; 16(8): 6927-49, 2011 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-21844842

RESUMO

After 6 months of operation a long-term biofilter was stopped for two weeks and then it was started up again for a second experimental period of almost 1.3 years, with high toluene loads and submitted to several physical and chemical treatments in order to remove excess biomass that could affect the reactor's performance due to clogging, whose main effect is a high pressure drop. Elimination capacity and removal efficiency were determined after each treatment. The methods applied were: filling with water and draining, backwashing, and air sparging. Different flows and temperatures (20, 30, 45 and 60 °C) were applied, either with distilled water or with different chemicals in aqueous solutions. Treatments with chemicals caused a decrease of the biofilter performance, requiring periods of 1 to 2 weeks to recover previous values. The results indicate that air sparging with pure distilled water as well as with solutions of NaOH (0.01% w/v) and NaOCl (0.01% w/v) were the treatments that removed more biomass, working either at 20, 30 or 45 °C and at relatively low flow rates (below 320 L h(-1)), but with a high biodegradation inhibition after the treatments. Dry biomass (g VS) content was determined at three different heights of the biofilter in order to carry out each experiment under the same conditions. The same amount of dry biomass when applying a treatment was established so it could be considered that the biofilm conditions were identical. Wet biomass was used as a control of the biofilter's water content during treatments. Several batch assays were performed to support and quantify the observed inhibitory effects of the different chemicals and temperatures applied.


Assuntos
Poluição do Ar/prevenção & controle , Biodegradação Ambiental , Biotecnologia/métodos , Filtração/métodos , Biomassa , Reatores Biológicos , Biotecnologia/instrumentação , Destilação , Filtração/instrumentação , Concentração de Íons de Hidrogênio , Cinética , Consórcios Microbianos , Pressão , Hidróxido de Sódio/química , Hipoclorito de Sódio/química , Temperatura , Tolueno/química , Tolueno/metabolismo , Compostos Orgânicos Voláteis/química , Compostos Orgânicos Voláteis/metabolismo , Água
14.
Int J Neural Syst ; 21(3): 225-46, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21656925

RESUMO

Background modeling and foreground detection are key parts of any computer vision system. These problems have been addressed in literature with several probabilistic approaches based on mixture models. Here we propose a new kind of probabilistic background models which is based on probabilistic self-organising maps. This way, the background pixels are modeled with more flexibility. On the other hand, a statistical correlation measure is used to test the similarity among nearby pixels, so as to enhance the detection performance by providing a feedback to the process. Several well known benchmark videos have been used to assess the relative performance of our proposal with respect to traditional neural and non neural based methods, with favourable results, both qualitatively and quantitatively. A statistical analysis of the differences among methods demonstrates that our method is significantly better than its competitors. This way, a strong alternative to classical methods is presented.


Assuntos
Inteligência Artificial , Interpretação de Imagem Assistida por Computador/métodos , Modelos Estatísticos , Redes Neurais de Computação , Gravação em Vídeo/métodos , Algoritmos , Benchmarking
15.
Hand (N Y) ; 6(1): 27-33, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22379435

RESUMO

PURPOSE: We had evaluated our experience in the treatment of displaced and comminuted radial head fractures with pyrocarbon radial head prosthesis. METHODS: From May 2003 to July 2008, radial head prostheses were performed in 47 patients. There were 29 female and 18 male with mean age 51 (34-70 years). The follow-up was a mean of 48 (12-60 months). Fractures of the radial head have been classified by Hotchkiss. The indications for a radial head replacement were type III fractures in 27 cases, type IV fractures in ten cases, comminuted radial fracture associated with disruption of the medial collateral ligament in three cases, Monteggia variant in five cases, and Essex-Lopresti in two cases. Functional outcomes were assessed by visual analog scales (VAS) of pain, joint motion and stability, and using the Mayo Elbow Performance Index. RESULTS: The mean VAS score for elbow pain was 1 (0.5-2.1). Patients showed an average arc of motion from 6° to 140°, with 75° of pronation and 67° of supination. By using the Mayo Elbow Performance Index, 42 patients had good/excellent results, with three fair and two poor outcomes. Complications were two implant dislocations, one elbow stiffness, one dissociation of the implant, one stem rupture, and two posterior interosseous nerve palsy that recovered from 5 to 8 weeks. We had not seen persistent instability, infection, synostosis, severe degenerative changes, or impingement. CONCLUSIONS: The treatment of comminuted radial head fracture with pyrocarbon implant usually gives an optimal result depending on the severity of the initial injury and the presence of associated lesions. The size of the prosthesis is often overestimated, causing restriction in motion due to impingement, overstuffing, or dislocations.

16.
Molecules ; 14(9): 3313-38, 2009 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-19783927

RESUMO

The synthesis and cytotoxic activity of a series of twenty six aroyl and heteroaroyl selenylacetic acid derivatives of general formula Ar-CO-Se-CH(2)-COOH or Heterar-CO-Se-CH(2)-COOH are reported. The synthesis was carried out by reaction of acyl chlorides with sodium hydrogen selenide, prepared in situ, and this led to the formation of sodium aroylselenides that subsequently reacted with alpha-bromoacetic acid to produce the corresponding selenylacetic acid derivatives. All of the compounds were tested against a prostate cancer cell line (PC-3) and some of the more active compounds were assessed against a panel of four human cancer cell lines (CCRF-CEM, HTB-54, HT-29, MCF-7) and one mammary gland-derived non-malignant cell line (184B5). Some of the compounds exhibited remarkable cytotoxic and antiproliferative activities against MCF-7 and PC-3 that were higher than those of the reference compounds doxorubicin and etoposide, respectively. For example, in MCF-7 when Ar = phenyl, 3,5-dimethoxyphenyl or benzyl the TGI values were 3.69, 4.18 and 6.19 microM. On the other hand, in PC-3 these compounds showed values of 6.8, 4.0 and 2.9 microM. Furthermore, benzoylselenylacetic acid did not provoke apoptosis nor did it perturb the cell cycle in MCF-7.


Assuntos
Compostos de Selênio/síntese química , Compostos de Selênio/farmacologia , Apoptose/efeitos dos fármacos , Ciclo Celular/efeitos dos fármacos , Morte Celular/efeitos dos fármacos , Linhagem Celular Tumoral , Proliferação de Células/efeitos dos fármacos , Avaliação Pré-Clínica de Medicamentos , Humanos , Masculino , Modelos Moleculares , Conformação Molecular , Compostos de Selênio/química
17.
Arch. esp. urol. (Ed. impr.) ; 54(6): 583-592, jul. 2001.
Artigo em Espanhol | IBECS | ID: ibc-1704

RESUMO

Se revisa la utilidad de la resonancia magnética (RM) en la evaluación de las masas renales, haciendo hincapie en las características morfológicas de las diferentes lesiones tumorales. Se hace especial mención del estadiaje del carcinoma de células renales. La RM aporta su capacidad multiplanar y facilita la detección y caracterización de lesiones. Asimismo, permite valorar las relaciones del tumor con las estructuras vecinas, de cara a plantear la estrategia quirúrgica. Por último, se valoran los aspectos técnicas y las indicaciones de la urografía por resonancia magnética, comparándola con otras técnicas de imagen (AU)


Assuntos
Humanos , Imagem por Ressonância Magnética , Carcinoma de Células Renais , Estadiamento de Neoplasias , Doenças Renais Císticas , Neoplasias Renais
18.
Rev. biol. trop ; 49(2): 643-646, Jun. 2001.
Artigo em Inglês | LILACS | ID: lil-333118

RESUMO

Three cruises, one in each of the main stream patterns in the area, were made on the central Mexican Pacific continental slope (May-June 1995, November 1995, and March 1996). Seven trawl sampling sites were defined per cruise, and in each site four bathymetric levels were sampled (20, 40, 60, and 80 m). During the warmest seasons, the highest abundance of Porichthys margaritatus was at 60 m. When the temperature of the bottom water was lower, in March 1996, the highest abundance of P. margaritatus moved towards 40 m. The depths with greatest abundance fluctuated between 18 and 21 degrees C, indicating a narrow temperature preference range. A Gaussian model was used to explain the relation between abundance and temperature.


Assuntos
Animais , Batracoidiformes , Análise de Variância , México , Distribuição Normal , Densidade Demográfica , Temperatura
19.
In. López Jaramillo, Patricio; Terán, Enrique; Espluges, Juan Vicente. Impacto de los problemas nutricionales en la salud pública. Quito, UC, nov. 1996. p.135-137.
Monografia em Espanhol | LILACS | ID: lil-337056
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