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1.
JBI Database System Rev Implement Rep ; 17(12): 2417-2451, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31821188

RESUMO

OBJECTIVES: The objective of this review was to evaluate the cost-effectiveness of antimicrobial therapy for patients with carbapenem-resistant Klebsiella pneumoniae infection. INTRODUCTION: Among the main multi-resistant microorganisms, carbapenem-resistant K. pneumoniae is responsible for the mortality of 40% of patients following 30 days of infection. Treatment for carbapenem-resistant K. pneumoniae infection entails the use of high-cost antimicrobials. Inappropriate use of antimicrobials can increase the cost of treatment fourfold. This review aimed to evaluate the cost-effectiveness of antimicrobial therapy treatment for patients with carbapenem-resistant K. pneumoniae infection to better inform decision making in hospital services. INCLUSION CRITERIA: The review included studies on participants 18 years or over with carbapenem-resistant K. pneumoniae infection who had undergone antimicrobial therapy in hospital and acute care services. Studies that compared the cost-effectiveness of different antimicrobial therapy for carbapenem-resistant K. pneumoniae infection were included. Outcome measures were cost per unit of effect expressed in clinical outcome units; this included cost per avoided death, cost per prevention of sepsis and cost per duration of stay. Economic studies with a cost-effectiveness design were considered, as well as modeling studies. METHODS: A three-step search strategy was utilized to locate studies published in English, Spanish or Portuguese, with no date restrictions. Two independent reviewers screened titles and abstracts and the full texts of potentially relevant studies for eligibility. Methodological quality was assessed by two independent reviewers using the JBI critical appraisal checklist for economic evaluations. Data were extracted from included studies using the standardized JBI data extraction tool. Data were synthesized using narrative, tables and the JBI Dominance Ranking Matrix. RESULTS: This review identified eight studies that evaluated the cost-effectiveness of different treatments for carbapenem-resistant K. pneumoniae infection. The results of this study demonstrated that there was no gold standard treatment for carbapenem-resistant K. pneumoniae infection, hence treatment was generally directed by colonization pressure and resistance profiles. Furthermore, due to the moderate quality and limited number of studies, there was high uncertainty of the values of the cost-effectiveness ratio. CONCLUSIONS: Ofloxacin appears to be the most cost-effective treatment; however, conclusions are limited due to the small number and low quality of studies.

4.
JBI Database System Rev Implement Rep ; 16(2): 336-344, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29419620

RESUMO

REVIEW QUESTION/OBJECTIVE: The objective of this review is to evaluate the cost-effectiveness of antimicrobial therapy treatment for inpatients infected with Klebsiella pneumoniae carbapenemase.More specifically, the review question is: What is the best evidence on the cost-effectiveness of the antimicrobial treatment for inpatients infected with Klebsiella Pneumoniae Carbapenemase?"


Assuntos
Anti-Infecciosos/economia , Infecção Hospitalar/tratamento farmacológico , Pacientes Internados/estatística & dados numéricos , Infecções por Klebsiella/tratamento farmacológico , Klebsiella pneumoniae , Proteínas de Bactérias , Análise Custo-Benefício , Infecção Hospitalar/economia , Humanos , Infecções por Klebsiella/economia , Projetos de Pesquisa , Revisão Sistemática como Assunto , beta-Lactamases
5.
Enferm. glob ; 16(46): 464-476, abr. 2017. tab
Artigo em Espanhol | IBECS | ID: ibc-161743

RESUMO

Educación para la salud se considera un medio muy importante para ampliar los conocimientos y prácticas relacionadas con conductas saludables de los individuos. Así, el estudio tiene como objetivo caracterizar las producciones científicas y describir el trabajo de las enfermeras en las prácticas de educación en salud en la escuela. Es una revisión integradora de la literatura en las bases LILACS y BDENF. A través de los criterios de inclusión se seleccionaron 20 artículos que respondieron a la pregunta: ¿cómo la enfermera actúa en las prácticas de educación para la salud en el contexto escolar? Los resultados emergieron tres categorías para el análisis: «Educación para la salud y la cuestión de la salud pública en la escuela», «Enfermería y educación para la salud en la escuela» y «Medidas adoptadas en el ámbito escolar.» A partir de 2010 se produjo un aumento significativo de publicaciones, estudios predominantemente con un enfoque cualitativo. Con todo, se percibe la complejidad de las prácticas de educación para la salud en el entorno escolar y la debilidad existente en publicaciones científicas sobre la inclusión de las enfermeras en la escuela (AU)


A educação em saúde é considerada um meio bastante importante para ampliação do conhecimento e práticas relacionadas aos comportamentos saudáveis dos indivíduos. Dessa forma, o estudo tem como objetivo aracterizar as produções científicas e descrever a atuação do enfermeiro nas práticas de educação em saúde na escola. Trata-se de uma revisão integrativa da literatura nas bases LILACS e BDEnf. Por meio dos critérios de inclusão selecionou-se 20 artigos, que responderam a seguinte questão: de que forma o enfermeiro atua nas práticas de educação em saúde no contexto escolar? Os resultados emergiram três categorias para a análise: «Educação em saúde e a problemática da saúde pública na escola», «Enfermagem e a educação em saúde na escola» e «Ações desenvolvidas no ambiente escolar». A partir de 2010 houve um aumento significativo nas publicações, com predomínio de estudos com abordagem qualitativa. Contudo, percebeu-se a complexidade que envolve as práticas de educação em saúde em âmbito escolar e a fragilidade existente nas publicações científicas no que tange a inserção do enfermeiro no ambiente escolar (AU)


Health education is considered a very important means to expand the knowledge and practices related to healthy behaviors of individuals. Thus, the study aims aracterizar scientific productions and describe the work of nurses in health education practices in school. It is an integrative literature in LILACS and BDEnf bases. Through the inclusion criteria was selected 20 articles who responded to the question: how the nurse acts in health education practices in the school context? The results emerged three categories for analysis: «Health education and the issue of public health at school», «Nursing and health education at school 'and' Actions taken in the school environment.» From 2010 there was a significant increase in publications, predominantly studies with a qualitative approach. However, he realized the complexity involved in health education practices in the school environment and the existing weakness in scientific publications regarding the inclusion of nurses at school (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Educação em Saúde/organização & administração , Educação em Saúde/normas , Educação em Enfermagem/métodos , Serviços de Saúde Escolar , Saúde Pública/educação
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