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J Am Dent Assoc ; 151(6): 399-406, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32450978


BACKGROUND: Dental features have been considered a potential target of verbal bullying (VB) among school-aged children. The authors conducted a study to investigate the association between the presence of oral disorders and the occurrence of VB among 8- through 10-year-old school-aged children. METHODS: The study included 445 school-aged children 8 through 10 years old. VB was verified by a specific validated question from the Child Perceptions Questionnaire 8-10 index. Oral disorders such as untreated caries, fluorosis, clinical consequences of untreated caries, and malocclusion were evaluated. The Pearson χ2 test and bivariate and multivariate conditional logistic regression analyses were used for statistical analysis. RESULTS: A total of 390 school-aged children completed the study. The results of the multivariate logistic regression model showed that a severe malocclusion (odds ratio [OR], 2.29; 95% confidence interval [CI], 1.03 to 5.10), a greater maxillary misalignment (OR, 2.23; 95% CI, 1.05 to 4.73), and the presence of a tooth with pulp exposure (OR, 2.93; 95% CI, 1.58 to 5.45) were significantly associated with the occurrence of VB. CONCLUSION: Children aged 8 through 10 years with a severe malocclusion, larger maxillary misalignment, or the presence of pulp exposure had increased odds of experiencing VB compared with children without those oral health conditions. PRACTICAL IMPLICATIONS: Once oral disorders involved in VB are identified, appropriate approaches should be used to address this issue. With this course of action, oral health care professionals may use the treatment and preventive care to eliminate potential factors for peer aggression.

Bullying , Cárie Dentária , Brasil , Estudos de Casos e Controles , Criança , Estudos Transversais , Humanos , Saúde Bucal , Prevalência , Qualidade de Vida , Inquéritos e Questionários
Arch Oral Biol ; 110: 104597, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31739076


OBJECTIVES: To systematically review and evaluate what is known regarding contemporary biological therapy capable of accelerating orthodontic tooth movement (OTM) in animal model. MATERIALS AND METHODS: MedLine, Scopus, Web of Science and OpenGrey were searched without restrictions until June 2019. Following study retrieval and selection, relevant data was extracted using a standardized table. Risk of bias (RoB) assessment was performed using the Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) tool. RESULTS: Fifty-one animal studies were included. Two biological therapies were identified as capable of accelerating the OTM: chemical methods (49 studies) and gene therapy (2 studies). The main substances that increased the OTM rate were cytokines (13 studies), followed by growth factors (6 studies) and hormones (5 studies). Most studies were assessed to be at unclear or high RoB. The application protocols, measurement and reporting of outcomes varied widely and methodologies were not adequately reported. CONCLUSIONS: Although biological therapies to accelerate OTM have been widely tested and effective in preclinical studies, the validity of the evidence is flawed to support translational of these results. There is a need for well-designed experimental studies to translate these methods for clinical field.

Terapia Biológica , Técnicas de Movimentação Dentária , Animais , Modelos Animais de Doenças , Proteômica
Spec Care Dentist ; 39(4): 362-374, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31144360


A systematic literature search was conducted (through April 2017), using Web of Science, PubMed and Virtual Health Library, manual reference list, and grey literature searches. The quality of the studies was evaluated using the Newcastle-Ottawa Quality Assessment Scale. The meta-analysis was performed using R software. A total of 30 studies was included in this review. From a total of 25 studies included in the meta-analysis, the prevalence of oral and maxillofacial injuries among epileptic subjects was 19%. Among the epileptic patients who suffered some type of injury due to epileptic seizures, 52% had facial soft tissue injuries (95%CI: 28-75%), 18% suffered dental trauma (95%CI: 11-29%), and 12% (95%CI: 4-28%) suffered maxillofacial fractures. Epileptic patients were more likely to have oral and maxillofacial injuries than healthy individuals (OR: 5.22, 95%CI: 2.84-9.36) and subjects with psychogenic nonepileptic seizures (OR: 2.77, 95%CI: 1.28-5.99), but not than patients with special needs (OR: 2.45,95%CI: 0.95-6.31).

Epilepsia , Traumatismos Maxilofaciais , Traumatismos Dentários , Face , Humanos , Prevalência
Qual Life Res ; 27(10): 2477-2489, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29797177


OBJECTIVE: The purpose of this systematic review was to assess the impact of third molar removal on patient's quality of life. METHODS: To address the study purpose, investigators designed and implemented a systematic review. The primary outcome variable was the quality of life after third molar extraction. An electronic search was conducted through March, 2017, on the PUBMED, Virtual Health Library (VHL), Web of Science, and OVID, to identify relevant literatures. Research studies (randomized or non-randomized clinical trials) were included that evaluated the quality of life in individuals before and after third molar extraction, using validated measures of oral health-related quality of life with quantitative approach, besides procedures performed under local anesthesia. The R software was used to measure the mean difference on the quality of life between the preoperative period and follow-up days. RESULTS: A total of 1141 studies were identified. Of this total, 13 articles were selected in the present systematic review, of which six studies were included in the meta-analysis. All of these 13 articles used the OHIP-14, and 4 of this 13 used OHQoLUK-16 to evaluate the quality of life. Regarding quality assessment, four of the 13 included studies in this review received a maximum score of 9 points, according to the Newcastle-Ottawa (NOS). The OHIP-14 mean score on the first postoperative day was 17.57 (95% CI 11.84-23.30, I2 = 96%) higher than the preoperative period. On the seventh postoperative day, the quality of life assessed by OHIP-14 got worse again. CONCLUSION: This systematic review revealed that the highest negative impact on quality of life of individuals submitted to third molar surgery was observed on the first postoperative day, decreasing over the follow-up period.

Dente Serotino/cirurgia , Qualidade de Vida/psicologia , Extração Dentária/métodos , Adulto , Feminino , Humanos , Adulto Jovem
Braz Oral Res ; 31: e111, 2017 Dec 18.
Artigo em Inglês | MEDLINE | ID: mdl-29267672


The aim of this study was to evaluate the correlation between the Child Perceptions Questionnaire 8 to 10 (CPQ8-10) and child-Oral Impact on Daily Performances (child-OIDP) indexes according to their total and item scores, as well as assess the discriminative validity of these assessment tools regarding dental caries and malocclusion among schoolchildren. A sample of 300 children aged between 8 and 10 years answered the questionnaires in two distinct steps. First, half of the sample (G1 = 150) answered the CPQ8-10 and the other half (G2 = 150) answered the child-OIDP. A week after, G1 answered the child-OIDP and G2 answered the CPQ8-10. Dental Aesthetic Index and WHO criteria were used to categorize malocclusion and dental caries, respectively. Descriptive analysis, Spearman's correlation and Mann-Whitney test were performed in this study. The CPQ8-10 and child-OIDP demonstrated a statistically significant and moderate correlation between their total scores. Regarding the discriminative validity, CPQ8-10 demonstrated a significant association between the "emotional status" daily activity and dental caries, and between the "eating", "sleeping", and "studying" daily activities and malocclusion. Concerning the child-OIDP, a significant difference was found only between the "social contact" activity and presence of dental caries. Both instruments were not capable of distinguishing children with and without dental caries and/or malocclusion by their total scores. However, the instruments were able to discriminate between children with and without those oral disorders in different dimensions. Thus, the CPQ8-10 and the child-OIDP demonstrated a different capacity to assess the impact on OHRQoL among schoolchildren.

Cárie Dentária/diagnóstico , Má Oclusão/diagnóstico , Inquéritos e Questionários/normas , Atividades Cotidianas , Brasil/epidemiologia , Criança , Estudos Transversais , Índice CPO , Cárie Dentária/epidemiologia , Cárie Dentária/fisiopatologia , Feminino , Humanos , Masculino , Má Oclusão/epidemiologia , Má Oclusão/fisiopatologia , Saúde Bucal/estatística & dados numéricos , Prevalência , Qualidade de Vida , Reprodutibilidade dos Testes , Estatísticas não Paramétricas