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1.
Clin Oral Investig ; 2021 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-34775517

RESUMO

OBJECTIVES: The main objective of this study was to enhance the blockage of dentinal tubules using nanobioglass in the presence of diode (980 nm) and Nd:YAG lasers in order to reduce permeability and dentin hypersensitivity. MATERIALS AND METHODS: Thirty-six dentinal samples were randomly divided into 6 subgroups (n = 6): (A) control, (B) diode laser (980 nm, 3-W), (C) Nd:YAG laser (1064, 1.0-W), (D) nanobioglass, (E) nanobioglass + diode laser (980 nm), (F) nanobioglass + Nd:YAG laser. The average number of open dentinal tubules was qualitatively and quantitatively evaluated by scanning electron microscopy (SEM). Data were evaluated by SPSS software version 22, Kruskal-Wallis test, and Mann-Whitney tests with Bonferoni's correction (α = 0.008). RESULTS: Based on the results of Mann-Whitney test, there was a significant difference in the mean number of open dentinal tubules between the control group and the other groups (p < 0.008). However, the difference among the other groups was not statistically significant (p > 0.008). CONCLUSIONS: Findings of this study showed that high-power laser radiation, such as Nd:YAG and diode (980 nm) alone or with nanobioglass, has a significant effect on the blockage of dentinal tubules. CLINICAL RELEVANCE: Introduction of non-invasive methods with long-term and lasting effect on reducing pain and discomfort caused by dentin hypersensitivity.

2.
Dent Res J (Isfahan) ; 18: 71, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34760062

RESUMO

Background: The management of children's anxiety in dental offices is still a challenge for the treatment team. The most important factors which affect children's dental anxiety are the clinician-related factors and the physical factors of the dental operatory. Color is an environmental factor whose relationship with the perceptive and emotional factors of children has been reported. On the other hand, distraction is essential factors in a treatment environment that can be used to manage children's anxiety. Materials and Methods: In this randomized clinical trial study, from 132 6 to 9 years of age children, 52.3% were male, and 47.7% were female, with a mean age of 7.45 ± 1.1 years. The children's anxiety levels were determined using the Venham Picture Test and pulse oximetry before and after the administration of local anesthesia. The children were randomly assigned to two groups (n = 66): Group 1, music, and Group 2, animated cartoons. The data were analyzed with SPSS 25, using descriptive statistics and the statistical tests consisting of one-way analysis of variance (ANOVA), t-test, and repeated-measures ANOVA, followed by Tukey honestly significant difference tests. Statistical significance was set at P < 0.05. Results: The anxiety levels were the lowest in the blue and pink environments and the highest in the black and red. Anxiety levels between different colors in terms of physiologic markers and the questionnaire in each distraction technique at different intervals was significantly different. Conclusion: The use of blue, pink, green, and yellow for dentists' attire, and the interior design of the dental operatory decreased the child patients' anxiety.

3.
J Lasers Med Sci ; 12: e26, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34733749

RESUMO

Introduction: Periodontal disease and tongue coatings are among the major factors associated with oral malodor. The present study, comparatively evaluated the effects of the Er,Cr:YSGG laser and Halita mouthwash as adjunctive treatments to nonsurgical periodontal debridement on oral malodor reduction in chronic periodontitis patients. Methods: Sixty patients with stage II and III chronic periodontitis and bad breath. The patients were randomly divided into two groups (n=30). After conventional scaling and root planing, patients in group 1 underwent Er,Cr:YSGG laser (Waterlase; Biolase, San Clemente, CA, USA) irradiation of the internal surface of the pockets (1.5 W, 30 Hz, 20% A, 40% W) and the dorsum of the tongue (1 W, 30 Hz, 20% A, 40% W) immediately after SRP and on the third and seventh days. Group 2 patients were asked to use Halita mouthwash twice daily for one week. Baseline, 1 and 3-month post-treatment measurements of plaque index (PI), probing pocket depth (PPD), clinical attachment level (CAL), gingival index (GI), bleeding on probing (BOP) and organoleptic assessment of Halitosis severity were performed. Results: Significant improvement in all parameters was noted in both groups after 1 and 3 months, compared with baseline (P < 0.05). The two groups had significant reductions which occurred in PPD, CAL and BOP levels and the organoleptic score in 1 and 3 months after the intervention (P < 0.05). Conclusion: Er,Cr:YSGG laser irradiation and Halita mouthwash as adjuncts to non-surgical periodontal therapy are both effective in the treatment of oral malodor and improvement of periodontal parameters.

4.
Maedica (Bucur) ; 16(2): 230-238, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34621345

RESUMO

This study aimed to assess the anatomical variations of the mandibular symphysis in a normal occlusion population using cone-beam computed tomography (CBCT). This retrospective cross-sectional study evaluated 200 CBCT scans of patients aged ≥17 with class I occlusion, 1-3 mm overbite and overjet, and <3 mm crowding. The CBCT scans were obtained with NewTom 3G scanner with the exposure settings of 110 kVp, 1.2 mA, 5.4 s time, and six-inch field of view and saved in NNT Viewer. The anterior loop length, labial bone thickness, mandibular bone height at the symphysis, and cortical bone thickness at the right and left canine teeth and central and lateral incisors were measured and compared between males and females and different age groups using one-way ANOVA. The intra- and inter-observer agreements for all landmarks were ICC >0.9 (excellent). The mean length of the anterior loop in females was significantly greater than that in males (P=0.02). Different age groups had significant differences in cortical bone width at the site of the left canine (P=0.03) and vertical bone height at the site of the right central incisor (P=0.05). The majority of parameters related to the mandibular symphysis were greater in normal occlusion males than females. Preoperative CBCT assessment of the mandibular symphysis can greatly help in diagnosis and treatment planning as well as bone harvesting from this area.

5.
Int Orthod ; 19(4): 612-621, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34607784

RESUMO

INTRODUCTION: This randomized controlled clinical trial aimed to assess the effect of LED5 and LLLT6 in a three-arm parallel setting. METHODS: Sixty patients who needed the maxillary first premolar extraction were allocated to three groups using the stratified block randomization method. In the LED group, a custom-made device with a wavelength of 640nm and a power density of 40 mW/cm2 was used 5min/day. In the laser group, Ga Al As7 laser with a wavelength of 810nm and a power of 100 mW was used on days 0, 3, 30, and 60 each time for 18seconds. Patients in the control group received placebo treatment as the laser group protocol, using a coated light cure device. Models were made at baseline and monthly until the end of the retraction. The rate of canine retraction was the primary outcome, while canine rotation and pain were secondary outcomes. The final data were anonymous for the outcome assessor and statistical consultant. Data were analyzed per protocol using a linear mixed model. RESULTS: The rate of canine retraction significantly increased by 60.8% in the laser group, while it increased not significantly by 26% in the LED group compared with the control group. There was no significant difference among the groups in terms of tooth rotation and pain. CONCLUSIONS: LLLT can accelerate orthodontic tooth movement (OTM). LED with the present setting couldn't increase the rate of OTM. LLLT and LED did not affect canine rotation or pain. TRIAL REGISTRATION: IRCT20120220009086N4. On 1 June 2019 was retrospectively registered.

6.
Imaging Sci Dent ; 51(2): 167-174, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34235062

RESUMO

Purpose: Sex determination can be done by morphological analysis of different parts of the body. The mastoid region, with its anatomical location at the skull base, is ideal for sex identification. Statistical shape analysis provides a simultaneous comparison of geometric information on different shapes in terms of size and shape features. This study aimed to investigate the geometric morphometry of the inter-mastoid triangle as a tool for sex determination in the Iranian population. Materials and Methods: The coordinates of 5 landmarks on the mastoid process on the 80 cone-beam computed tomographic images (from individuals aged 17-70 years, 52.5% female) were registered and digitalized. The Cartesian x-y coordinates were acquired for all landmarks, and the shape information was extracted from the principal component scores of generalized Procrustes fit. The t-test was used to compare centroid size. Cross-validated discriminant analysis was used for sex determination. The significance level for all tests was set at 0.05. Results: There was a significant difference in the mastoid size and shape between males and females (P<0.05). The first 2 components of the Procrustes shape coordinates explained 91.3% of the shape variation between the sexes. The accuracy of the discriminant model for sex determination was 88.8%. Conclusion: The application of morphometric geometric techniques will significantly impact forensic studies by providing a comprehensive analysis of differences in biological forms. The results demonstrated that statistical shape analysis can be used as a powerful tool for sex determination based on a morphometric analysis of the inter-mastoid triangle.

7.
Contemp Clin Dent ; 12(2): 128-132, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34220151

RESUMO

Aims: Mandibular para-radicular third molar radiolucencies (MPRs) may be mistaken for pathological lesions, leading to misdiagnosis and mistreatment. This study sought to assess the appearance of MPRs on cone-beam computed tomography (CBCT). Settings and Design: This was a descriptive, cross-sectional study. Materials and Methods: This study evaluated 770 CBCT of patients presenting to the dental school of Hamadan University of Medical Sciences. Demographic information, unilateral or bilateral presence, shape and prevalence of MPRs observed on axial and sagittal sections, their density, thinning of cortical margin, internal trabeculation, bony expansion, and mean height and width of MPRs were all evaluated. Statistical Analysis Used: Data were analyzed using SPSS version 22.0 and descriptive statistics. Chi-square test was used. Results: Seventy (9.1%) patients had a total of 82 MPRs, including 51 (72.86%) females. The prevalence of MPRs in females was more than males (P = 0.011). The majority of MPRs were unilateral 58 (70.73%), mostly round in shape 48 (58.54%), and were mostly associated with third molars with distoangular impaction 47 (57.31%); this difference was statistically significant (P < 0.001). Furthermore, in 47 (57.32%) patients, MPRs had less density than the surrounding bone. MPRs were not associated with expansion or root resorption in any patient. Conclusion: Differentiation of MPRs from the pathological lesions is important to make a decision about further imaging or referral for surgical treatment. MPRs are often considered normal since they do not cause root resorption or bone expansion and do not affect the lamina dura. MPRs are more commonly found adjacent to third molars with distoangular impaction.

8.
Int Orthod ; 19(3): 433-444, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34088620

RESUMO

OBJECTIVE: This study aimed to evaluate the mandibular skeletal asymmetry in pre-orthodontic patients with the unilateral posterior dental crossbite (UPCB). MATERIALS AND METHODS: Using a retrospective design, 30 pre-orthodontic patients with a UPCB, (16 on the right side, 14 on the left side), 18 females and 12 males were selected (mean age: 21.2±4.92 years), along with 30 controls matched by age and sex with cl I occlusal relationship (mean age: 21.9±4.80 years). The patients were from an Orthodontic Department of Dental Faculty of Hamadan University of Medical Sciences and a private office from 2009 to 2013. In the UPCB group, at least one molar tooth was in the crossbite position. All the patients had initial CBCT1 and pre-orthodontic study models. 10 linear and 3 angular measurements were performed to evaluate the mandibular skeletal asymmetry. repeated measure-ANCOVA2 by controlling the effect of age and sex, T-test and paired-samples t-test were used for comparisons. Measurement's reliability was measured with ICC3 test. RESULTS: There was a positional deviation of mandible to the crossbite side 95% CI4 (0.166 - 1.087). The intergroup analysis showed that Corpus Length (P≤0.014), Ramus Angle in frontal view (P≤0.046), and Condylar-Width in axial view (P≤0.029) in the crossbite side of the case group were significantly smaller than the control group. In the subjects with UPCB, mandibular condylar width was smaller in the crossbite side (17.31±2.50) relative to the non-crossbite side (18.06±2.18). CONCLUSIONS: The adults with dental UPCB, in addition to deviation to crossbite side, may show smaller condylar head and Corpus length in crossbite side relative to the control group.

9.
Int Orthod ; 19(3): 406-414, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34049835

RESUMO

OBJECTIVE: Chlorhexidine gluconate is currently the most effective oral antimicrobial agent against microorganisms, but discoloration of the teeth prevents its long-term use and can reduce patient cooperation. In this study, the effect of chlorhexidine and a diluted chlorhexidine-based, fluoride, cetylpyridinium and vitamin added mouth rinse (Orthokin) on stain index in fixed orthodontic patients was compared. MATERIALS AND METHODS: This study was performed as a double blind randomized controlled trial on 50 patients undergoing fixed orthodontic treatment in the age group of 14-30 years. The patients were categorized as two groups of chlorhexidine and Orthokin mouth rinses and were asked to use mouthwash for eight weeks. Groups were matched according to colouring food consumption. Extrinsic staining index was assessed by modified Loben technique. Data was analysed by SPSS software. P value was set to be 0.05. RESULTS: In the chlorhexidine group, the stain extent index and overall stain index were increased significantly at 8 weeks (P<0.001 and P=0.002, respectively). However, the increase in stain intensity index was insignificant (P=0.07). In Orthokin group, the changes in stain extent, stain intensity and overall stain were insignificant (P=0.66, P=1.000, P=0.47, respectively). CONCLUSION: According to the results of the present study, chlorhexidine mouthwash causes more staining of teeth compared to Orthokin mouthwash. It seems that lower concentrations of chlorhexidine can be prescribed to orthodontic patients. Although these compounds are effective in sense of oral hygiene, they do not cause significant discoloration.

10.
BMC Infect Dis ; 21(1): 390, 2021 Apr 27.
Artigo em Inglês | MEDLINE | ID: mdl-33906638

RESUMO

BACKGROUND: Late-diagnosis of HIV is a major challenge for the control and prevention of AIDS in the world. The present study aimed to specify factors associated with the late diagnosis of HIV in Iran from 1987 to 2016. METHODS: In this retrospective cohort study, data for 4402 diagnosed HIV/AIDS patients were extracted from 158 behavioral disease counseling centers of 31 Iranian provinces. We defined late diagnosis as having a CD4 count less than 350 within 3 months after diagnosis. Multiple logistic regression analysis was used to determine the factors influencing late diagnosis. Moreover, we used multivariate Cox regression to assess the association of these factors with the patients' survival. RESULTS: In this study, the prevalence of late diagnosis among the patients was 58.2%. People aged 50 years and over (adjusted OR = 3.55), transmission through blood transfusion (adjusted OR = 2.89), co-infection with tuberculosis (adjusted OR = 2.06), and male gender (adjusted OR = 1.38) were the strongest predictors for late diagnosis of HIV. On the other hand, baseline CD4 (adjusted HR = 2.21), people aged 50 and over (adjusted HR = 1.81), male gender (adjusted HR = 1.76), being a widow (adjusted HR = 1.68), people with unknown transmission way (adjusted HR = 18.24), people who inject drugs (adjusted HR = 1.87), diagnosis at previous years (adjusted HR = 2.45) and co-infection with tuberculosis (adjusted OR = 1.77) significantly associated with the survival of patients. CONCLUSION: The prevalence of late diagnosis is high among Iranian HIV/AIDS. The risk factors of late diagnoses include being males and aged 50 years and over, transmission through blood transfusion, and co-infection with tuberculosis. Therefore, implementation of screening programs for early diagnosis of HIV these high risk groups is recommended to Iranian health providers and policymakers.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Infecções Oportunistas Relacionadas com a AIDS/epidemiologia , Diagnóstico Tardio/efeitos adversos , HIV , Mycobacterium tuberculosis , Tuberculose/epidemiologia , Infecções Oportunistas Relacionadas com a AIDS/mortalidade , Adulto , Contagem de Linfócito CD4 , Comorbidade , Aconselhamento , Feminino , Seguimentos , Humanos , Irã (Geográfico)/epidemiologia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Análise de Sobrevida , Taxa de Sobrevida , Adulto Jovem
11.
Int J Dent ; 2021: 6659146, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33927764

RESUMO

This study investigates the antibacterial effects of erbium chromium laser at 2780 nm, silver nanoparticles, and erbium chromium along with silver nanoparticles on Enterococcus faecalis in comparison with sodium hypochlorite. In the present study, 90 extracted human single-rooted teeth were selected and standardized to a length of 15 mm. The canals were prepared by V-taper Gold rotary files and then incubated with E. faecalis for 21 days. The samples were divided into four experimental groups including hypochlorite sodium, silver nanoparticle, erbium chromium laser, and erbium chromium laser along with silver nanoparticle groups. Results showed that there was a significant reduction in colony count for all groups after interventions. Moreover, there was a significant reduction in the colony count for sodium hypochlorite group in comparison with another groups, and this group showed the highest reduction of colony count. There was a significant difference between silver nanoparticles and erbium chromium laser groups in colony count. According to the results, the silver nanoparticles offered strong antibacterial effects on E. faecalis and therefore can decrease bacterial colonies, while the use of the laser, despite the reduction of the bacterial colony, could not be sufficiently used for disinfection of root canal system.

12.
Imaging Sci Dent ; 51(1): 41-47, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33828960

RESUMO

Purpose: This study aimed to compare the accuracy of 3-dimensional (3D) printed models derived from multidetector computed tomography (MDCT) and cone-beam computed tomography (CBCT) systems with different fields of view (FOVs). Materials and Methods: Five human dry mandibles were used to assess the accuracy of reconstructions of anatomical landmarks, bone defects, and intra-socket dimensions by 3D printers. The measurements were made on dry mandibles using a digital caliper (gold standard). The mandibles then underwent MDCT imaging. In addition, CBCT images were obtained using Cranex 3D and NewTom 3G scanners with 2 different FOVs. The images were transferred to two 3D printers, and the digital light processing (DLP) and fused deposition modeling (FDM) techniques were used to fabricate the 3D models, respectively. The same measurements were also made on the fabricated prototypes. The values measured on the 3D models were compared with the actual values, and the differences were analyzed using the paired t-test. Results: The landmarks measured on prototypes fabricated using the FDM and DLP techniques based on all 4 imaging systems showed differences from the gold standard. No significant differences were noted between the FDM and DLP techniques. Conclusion: The 3D printers were reliable systems for maxillofacial reconstruction. In this study, scanners with smaller voxels had the highest precision, and the DLP printer showed higher accuracy in reconstructing the maxillofacial landmarks. It seemed that 3D reconstructions of the anterior region were overestimated, while the reconstructions of intra-socket dimensions and implant holes were slightly underestimated.

13.
BMC Res Notes ; 14(1): 114, 2021 Mar 25.
Artigo em Inglês | MEDLINE | ID: mdl-33766121

RESUMO

OBJECTIVE: CD4 Lymphocyte Count (CD4) is a major predictor of HIV progression to AIDS. Exploring the factors affecting CD4 levels may assist healthcare staff and patients in management and monitoring of health cares. This retrospective cohort study aimed to explore factors associated with CD4 cell counts at the time of diagnosis in HIV patients using Poisson, Generalized Poisson, and Negative Binomial regression models. RESULTS: Out of 4402 HIV patients diagnosis in Iran from 1987 to 2016, 3030 (68.8%) were males, and the mean age was 34.8 ± 10.4 years. The results indicate that the Negative Binomial model outperformed the other models in terms of AIC, log-likelihood and RMSE criteria. In this model, factors include sex, age, clinical stage and Tuberculosis (TB) co-infection were significantly associated with CD4 count (P < 0.05). CONCLUSION: Given the effect of age, sex, clinical stage and stage of HIV on CD4 count of the patients, adopting policies and strategies to increase awareness and encourage people to seek early HIV testing and care is advantageous.


Assuntos
Síndrome de Imunodeficiência Adquirida , Infecções por HIV , Adulto , Contagem de Linfócito CD4 , Progressão da Doença , Feminino , Infecções por HIV/diagnóstico , Humanos , Irã (Geográfico) , Masculino , Pessoa de Meia-Idade , Modelos Estatísticos , Estudos Retrospectivos , Adulto Jovem
14.
BMC Cardiovasc Disord ; 21(1): 38, 2021 01 18.
Artigo em Inglês | MEDLINE | ID: mdl-33461487

RESUMO

BACKGROUND: Due to the limited number of studies with long term follow-up of patients undergoing Percutaneous Coronary Intervention (PCI), we investigated the occurrence of Major Adverse Cardiac and Cerebrovascular Events (MACCE) during 10 years of follow-up after coronary angioplasty using Random Survival Forest (RSF) and Cox proportional hazards models. METHODS: The current retrospective cohort study was performed on 220 patients (69 women and 151 men) undergoing coronary angioplasty from March 2009 to March 2012 in Farchshian Medical Center in Hamadan city, Iran. Survival time (month) as the response variable was considered from the date of angioplasty to the main endpoint or the end of the follow-up period (September 2019). To identify the factors influencing the occurrence of MACCE, the performance of Cox and RSF models were investigated in terms of C index, Integrated Brier Score (IBS) and prediction error criteria. RESULTS: Ninety-six patients (43.7%) experienced MACCE by the end of the follow-up period, and the median survival time was estimated to be 98 months. Survival decreased from 99% during the first year to 39% at 10 years' follow-up. By applying the Cox model, the predictors were identified as follows: age (HR = 1.03, 95% CI 1.01-1.05), diabetes (HR = 2.17, 95% CI 1.29-3.66), smoking (HR = 2.41, 95% CI 1.46-3.98), and stent length (HR = 1.74, 95% CI 1.11-2.75). The predictive performance was slightly better by the RSF model (IBS of 0.124 vs. 0.135, C index of 0.648 vs. 0.626 and out-of-bag error rate of 0.352 vs. 0.374 for RSF). In addition to age, diabetes, smoking, and stent length, RSF also included coronary artery disease (acute or chronic) and hyperlipidemia as the most important variables. CONCLUSION: Machine-learning prediction models such as RSF showed better performance than the Cox proportional hazards model for the prediction of MACCE during long-term follow-up after PCI.


Assuntos
Transtornos Cerebrovasculares/epidemiologia , Doença da Artéria Coronariana/terapia , Técnicas de Apoio para a Decisão , Cardiopatias/epidemiologia , Aprendizado de Máquina , Intervenção Coronária Percutânea/efeitos adversos , Idoso , Transtornos Cerebrovasculares/diagnóstico , Transtornos Cerebrovasculares/mortalidade , Doença da Artéria Coronariana/diagnóstico , Doença da Artéria Coronariana/mortalidade , Feminino , Cardiopatias/diagnóstico , Cardiopatias/mortalidade , Humanos , Irã (Geográfico)/epidemiologia , Masculino , Pessoa de Meia-Idade , Intervenção Coronária Percutânea/instrumentação , Intervenção Coronária Percutânea/mortalidade , Modelos de Riscos Proporcionais , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Stents , Fatores de Tempo , Resultado do Tratamento
15.
Lasers Med Sci ; 36(5): 1109-1116, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33392782

RESUMO

The aim of this study was to evaluate the effect of 940 nm laser diode on class II composite cavities prior to bonding and restoration process on the postoperative sensitivity (POS). Thirty patients with two bilateral premolars with mesio or disto-occlusal carious lesions were evaluated. In each patient, the teeth were randomly divided into the control and laser groups. After cavity preparation and isolation and before the bonding process, the laser group was subjected to 940 nm irradiation (Epic 10, Biolase, USA) by 400 µ tip continuously at 100 mW with 398 J/cm2 energy density of tip, which was applied for 5 s at a distance of 2 mm on the axial wall of the cavity. In the control group, irradiation was performed by using the aiming beam. Access cavity was then restored with a composite resin. Cold sensitivity was measured using a cold spray application on the middle third of teeth buccal surface at baseline (before the intervention), 1, 14, and 30 days after the restoration by visual analog scale (VAS) criteria. The mean Friedman and Wilcoxon signed-rank tests were used for data analysis. It was shown that in both laser and control groups, the VAS was significantly decreased at all times compared to the baseline (p ≤ 0.05). There was no statistically significant difference between the mean VAS of two groups at baseline and first day (p ≤ 0.05), but at 14 and 30 days after the intervention, it was significantly lower in the laser group (p ≤ 0.05). The results of this study demonstrated that the cavity pretreatment with laser diode (940 nm) effectively reduces the postoperative sensitivity in class II composite restorations.


Assuntos
Resinas Compostas/farmacologia , Restauração Dentária Permanente/efeitos adversos , Sensibilidade da Dentina/etiologia , Sensibilidade da Dentina/prevenção & controle , Lasers Semicondutores/uso terapêutico , Boca , Adulto , Humanos , Período Pós-Operatório , Adulto Jovem
16.
Per Med ; 18(1): 31-42, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33393369

RESUMO

Aim: The study aimed to explore miR-600 and WT1 expression and its potential clinical significance in breast cancer. Materials & methods: The expression of miR-600 and WT1 in tumor and non-tumor adjacent tissues in 45 breast cancer patients as well as serum level of miR-600 in these patients and 45 healthy group were analyzed. Results: The expression level of miR-600 in tumor tissue and serum of patients was significantly lower than non-tumor adjacent tissues and serum of controls, respectively, while WT1 mRNA and protein levels were higher in tumor tissues compared with non-tumor adjacent tissues. The miR-600 expression was correlated with lymph node metastasis and clinical stage. Conclusion: The miR-600 acts as tumor suppressor and a diagnostic and prognostic biomarker in breast cancer patients.


Assuntos
Neoplasias da Mama/genética , Carcinoma Ductal/genética , MicroRNAs/genética , Proteínas WT1/genética , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Biomarcadores Tumorais , Neoplasias da Mama/patologia , Carcinoma Ductal/patologia , Estudos de Casos e Controles , Feminino , Regulação Neoplásica da Expressão Gênica , Humanos , Metástase Linfática , Pessoa de Meia-Idade , Invasividade Neoplásica , Estadiamento de Neoplasias , Prognóstico
17.
Health Promot Int ; 36(2): 397-405, 2021 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-32737481

RESUMO

The purpose of this study was to manage total quality management (TQM) to increase the standard of management policy and contribute to achieve the standards for health promotion hospitals (HPHs). This was a quasi-experimental intervention study. A total of 35 managers participated in this study were selected in the census. Based on the TQM components, educational items were provided as lectures, posters and pamphlets. The TQM questionnaire and HPHs checklist used to collect data in three different periods: before the interventions, immediately after the interventions and 3 months after the interventions (follow-up). The data analysis was done by means of SPSS software (version 23). The results showed that the average difference of the components of the qualitative groups (p < 0.001), education (p = 0.004), evaluation and feedback (p < 0.001), customer-orientation (p < 0.001), suggestion system (p = 0.024), leadership commitment (p < 0.001) was significant over the three periods. Excluding the employment status before the educational intervention (p = 0.002), there was no significant relationship between the demographic characteristics and mean score of TQM (p > 0.05). Based on the findings of this study, the educational interventions had a positive effect on quality management and management policy. Therefore, educational interventions should be accompanied by changes in the culture and management policies of the hospital to meet HPH standards.


Assuntos
Hospitais , Liderança , Gestão da Qualidade Total , Promoção da Saúde , Humanos , Políticas , Inquéritos e Questionários
18.
Braz. dent. sci ; 24(1): 1-9, 2021. tab, ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1145533

RESUMO

Objective: Sex determination is one of the most important parameters to identify in forensic science. Because the mastoid process is the most resistant to damage due to its position in the skull base, it can be used for sex determination. The purpose of this study was to measure the dimensions and convexity and internal angles of the mastoid process to present a model of sex determination in Iranian population. Material and methods: This study was performed on three-dimensional images of 190 Cone Beam Computed Tomography (CBCT) of 105 women and 85 men. On each CBCT the distance between the porion and the mastoid (PM), mastoid length (ML), the distance between the mastoidale and the mastoid incision (M-I), the mastoid height (MH), the mastoid width (MW), intermastoidale distance (IMD) the lateral surfaces of the left and right mastoids (IMLSD) and the Mastoid medial convergence angle (MMCA) was measured on both the right and the left. The data were analyzed by descriptive statistics, t-test, and discriminant function analysis. Results: Significant differences were found for all variables except MMCA and MF in both sex. All measured variables except MW were greater for men than women. The discriminant model achieved a total accuracy of 93.7%. Among the measured factors IMD and IMSLD had the most influence on sex determination. Conclusion: Measuring the dimensions of the mastoid process is a very good method for sex determination with high accuracy of 90% (AU)


Objetivo: A determinação do sexo é um dos parâmetros mais importantes para identificação na ciência forense. Por ser o processo mastóide resistente a danos, devido a sua posição na base do crânio, este poderia ser usado na determinação do sexo. O objetivo deste estudo foi mensurar as dimensões, convexidade e ângulos internos do processo mastóide para apresentar um modelo de determinação do sexo em uma população Iraniana. Material e métodos: Este estudo foi realizado em 190 imagens de tomografia computadorizada de feixe cônico (TCFC), sendo 105 mulheres e 85 homens. Em cada TCFC foram realizadas medidas no processo mastóide em comprimento (ML), altura (MH), largura (MW) em ambos os lados direito e esquerdo, também foi medida a distância entre o Pórion e o processo mastóide (PM), distância até incisura mastoidea (M-I), distância entre as superfícies mediais (IMD) distância entre as superfícies laterais dos processos direito e esquerdo (IMLSD) e o ângulo de convergência medial (MMCA). Os dados foram analisados por estatística descritiva, teste t e análise de função discriminante. Resultados: Diferenças significativas foram encontradas para todas as variáveis, exceto MMCA e MF em ambos os sexos. Todas as variáveis medidas, exceto MW, foram maiores para os homens do que para as mulheres. O modelo de análise de função discriminante alcançou uma precisão total de 93,7%. Entre os fatores medidos, o IMD e o IMSLD tiveram a maior influência na determinação do sexo. Conclusão: Podemos concluir que as dimensões do processo mastóide constituem um método para determinação do sexo, em população Iraniana, com precisão de 90% (AU)


Assuntos
Humanos , Masculino , Feminino , Análise para Determinação do Sexo , Tomografia Computadorizada de Feixe Cônico , Processo Mastoide
19.
Braz. dent. sci ; 24(2): 1-10, 2021. tab
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1177598

RESUMO

Objective: TThis study aimed to assess the knowledge level of Iranian dental practitioners about digital radiography (DR) and cone-beam computed tomography (CBCT). Material and Methods: In this cross-sectional study, a researcher-designed questionnaire was administered among 180 general dentists and specialists. The questionnaire had three main domains of demographic information, fifteen questions about knowledge of DR (advantages, disadvantages, physical properties) and twenty six questions about knowledge of CBCT (indications, applications, advantages, route of knowledge acquisition). Data were analyzed using descriptive statistics, t-test and Pearson's correlation coefficient. Results: Of 180 participants, 76 (42.2%) were females. The minimum, maximum and mean± standard deviation scores obtained in DR were 4, 14, and 9.031 ± 1.85 and in CBCT were 0,26 and 18.56 ± 4.81, respectively. In the CBCT domain, the participants had maximum knowledge about "low radiation dose" (72.8%) and minimum knowledge about the "role of CBCT in determination of bone density" (45%). In DR domain, the participants had maximum knowledge about "no need for radiographic films" (75.6%) and minimum knowledge about "not requiring manual processing" (15.6%). Overall, participants had higher level of knowledge about CBCT than DR. An inverse correlation was noted between age and work experience with the number of correct answers. However, no significant difference was noted in the knowledge level of males and females regarding CBCT or DR (p = 0.233 and p = 0.227, respectively). Conclusions: further education seem imperative for dentists in this respect for more efficient diagnosis and treatment planning, minimize patient radiation dose and save time and cost. (AU)


Objetivos: Avaliar o nível de conhecimento de dentistas iranianos sobre radiografia digital (RD) e tomografia computadorizada de feixe cônico (TCFC). Materiais e métodos: Neste estudo transversal, um questionário, elaborado por pesquisadores, foi aplicado a 180 dentistas clínicos geral e especialistas. O questionário tinha três domínios principais de informação demográfica, quinze questões sobre conhecimento de RD (vantagens, desvantagens, propriedades físicas) e vinte e seis questões sobre conhecimento de CBCT (indicações, aplicações, vantagens, protocolo de aquisição). Os dados foram analisados por meio de estatística descritiva, teste t e coeficiente de correlação de Pearson. Resultados: Dos 180 participantes, 76 (42,2%) eram do sexo feminino. Os escores mínimo, máximo e média ± desvio padrão obtidos na RD foram 4, 14 e 9,031 ± 1,85 e na CBCT foram 0, 26 e 18,56 ± 4,81, respectivamente. No domínio CBCT, os participantes tinham conhecimento máximo sobre "baixa dose de radiação" (72,8%) e conhecimento mínimo sobre o "papel da CBCT na determinação da densidade óssea" (45%). No domínio RD, os participantes possuíam conhecimento máximo sobre "não há necessidade de filmes radiográficos" (75,6%) e conhecimento mínimo sobre "não requer processamento manual" (15,6%). No geral, os participantes tinham maior nível de conhecimento sobre CBCT do que RD. Foi observado correlação inversa entre idade e experiência de trabalho com o número de acertos. No entanto, nenhuma diferença significativa foi observada no nível de conhecimento de homens e mulheres sobre TCFC ou RD (p = 0,233 e p = 0,227 respectivamente). Conclusão: Parece imperativo para os dentistas iranianos, mais educação nesse aspecto para diagnóstico e planejamento de tratamento mais eficientes, minimizar a dose de radiação para paciente, economizar tempo e custos. (AU)


Assuntos
Humanos , Intensificação de Imagem Radiográfica , Odontólogos , Tomografia Computadorizada de Feixe Cônico
20.
BDJ Open ; 6(1): 24, 2020 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-33298841

RESUMO

Considering the widespread use of smartphones and their applications (apps), as well as the undeniable role of reminders and apps in behavioral interventions, this study aimed to assess the efficacy of a smartphone app (Brush DJ) for oral hygiene compliance of patients with fixed orthodontic appliances. In this randomized clinical trial, 120 patients between 15 to 25 years who had just started fixed orthodontic treatment were randomly divided into two groups (n = 60). Control patients received conventional oral hygiene instruction, while patients in the intervention group were asked to use the Brush DJ smartphone app, after receiving conventional oral hygiene instruction. The plaque index (PI) and gingival index (GI) were measured at baseline (T0), and at 4 weeks (T1), 8 weeks (T2) and 12 weeks (T3) after the onset of study. A questionnaire was given to all patients to assess the frequency and duration of tooth brushing per day, and the frequency of app usage and reminder noticing in the intervention group. Improvements in PI and GI were noted in the intervention group; while these parameters increased in the control group. Significant differences were noted in PI and GI changes between the two groups (p < 0.001). Brushing frequency and duration were positively correlated with app usage during the follow-up period. Ultimately, we believe that smartphone apps, as motivators and reminders, can greatly help in improving the orthodontic patients' oral hygiene compliance, especially in adolescents.

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