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1.
Hematol., Transfus. Cell Ther. (Impr.) ; 42(2): 166-172, Apr.-June 2020. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1134025

RESUMO

ABSTRACT Objective: To describe the oral health status of patients with multiple myeloma and compare to a control group. Materials and methods: The medical history of the studied subjects was obtained from the medical records and through interviews. Trained examiners evaluated the oral mucosa, teeth, periodontium and imaging aspects. The dental status was evaluated by the decayed, missing and filled teeth index. The presence of bone lesions was investigated with cone beam computer tomography images of the jaws. Results: The most common oral mucosa features were paleness (31%) and coated tongue (14.3%) in the multiple myeloma group (N = 42); and coated (21.4%) and fissured tongue (10.7%) in the control group (N = 28). The mean DMFT index of patients with multiple myeloma was high, but not significantly different from controls (14.57 versus 19.69, p = 0.975). Hypodense lesions suggestive of multiple myeloma were observed in the jaws of 73.8% of the patients. Hypodense lesions related to teeth were detected in 33.3% of the patients and in 53.6% of the controls (p = 0.832). Conclusions: The studied population of multiple myeloma patients presented many oral health issues that needed attention. Thus, oral care should be included in the routine treatment to improve the quality of the oral status in these patients.

2.
Hematol Transfus Cell Ther ; 42(2): 166-172, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31582338

RESUMO

OBJECTIVE: To describe the oral health status of patients with multiple myeloma and compare to a control group. MATERIALS AND METHODS: The medical history of the studied subjects was obtained from the medical records and through interviews. Trained examiners evaluated the oral mucosa, teeth, periodontium and imaging aspects. The dental status was evaluated by the decayed, missing and filled teeth index. The presence of bone lesions was investigated with cone beam computer tomography images of the jaws. RESULTS: The most common oral mucosa features were paleness (31%) and coated tongue (14.3%) in the multiple myeloma group (N=42); and coated (21.4%) and fissured tongue (10.7%) in the control group (N=28). The mean DMFT index of patients with multiple myeloma was high, but not significantly different from controls (14.57 versus 19.69, p=0.975). Hypodense lesions suggestive of multiple myeloma were observed in the jaws of 73.8% of the patients. Hypodense lesions related to teeth were detected in 33.3% of the patients and in 53.6% of the controls (p=0.832). CONCLUSIONS: The studied population of multiple myeloma patients presented many oral health issues that needed attention. Thus, oral care should be included in the routine treatment to improve the quality of the oral status in these patients.

3.
Dentomaxillofac Radiol ; 49(2): 20190155, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31670576

RESUMO

OBJECTIVES: To verify quantitative differences of the mandibular cortical and trabecular bone between patients with multiple myeloma (MM) under bisphosphonate (BP) therapy and a control group never exposed to BP. METHODS: Clinical and demographic characteristics were collected through medical records and interviews. Mandibular cortical thickness (MCT) and fractal dimension (FD) were measured on cone beam computed tomography (CBCT) images, on the molar region, in both groups. Additionally, FD was measured on periapical digital intraoral radiography and results were compared to CBCT measurements. RESULTS: There were 33 patients with MM under BP therapy and 28 controls, with no significant differences in gender and age between groups. Pamidronate was used by all MM patients, either associated or not to other types of BP. The median MCT was higher in MM group exposed to BP (5.20 mm) than in controls (3.50 mm, p < 0.001). There were no significant differences in the median FD between patients in the MM group and controls, on CBCT (0.95 vs 0.90, p = 0.814) and periapical digital intraoral radiography (0.98 vs 0.96, p = 0.963), respectively, even when more than one type of BP was used. CONCLUSIONS: The MCT represents an useful tool in the detection of bone dimensional changes caused by BP, in patients with MM. Additional studies are necessary to improve the knowledge on the quantitative evaluation of trabecular jaw bone, in individuals with MM, under BP therapy.


Assuntos
Conservadores da Densidade Óssea , Difosfonatos , Mandíbula , Mieloma Múltiplo , Conservadores da Densidade Óssea/uso terapêutico , Tomografia Computadorizada de Feixe Cônico , Difosfonatos/uso terapêutico , Humanos , Arcada Osseodentária/diagnóstico por imagem , Arcada Osseodentária/efeitos dos fármacos , Mandíbula/diagnóstico por imagem , Mandíbula/efeitos dos fármacos , Mieloma Múltiplo/complicações , Radiografia Dentária Digital
4.
Oral Radiol ; 36(2): 168-176, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-31222625

RESUMO

PURPOSE: To establish an evaluation protocol for the identification and description of the variations in multiple myeloma (MM) lesions of the jaws, by means of cone-beam computed tomography (CBCT). MATERIALS AND METHODS: Tomography exams from 33 MM patients were evaluated in this retrospective observational study. The reconstructions were analyzed simultaneously, according to the established protocol, with the following description criteria: anatomic location, size, margins, inner aspect, relationship with adjacent structures, and presence or absence of a punched-out aspect. The exams were further subdivided into groups of patients using, or not bisphosphonates. RESULTS: There were osteolytic lesions in 100% of cases, most of which were extended to more than one anatomical region. Poorly defined margins were more frequent in the maxilla than in the mandible. Extensive bone resorption presenting multilocular areas was the most frequently observed aspect, being 86.2% for maxilla and 87.9% for mandible. In relation to bisphosphonates, patients who used the medication had more poorly defined bone margins and contortions (68.6%) than those who did not undergo drug therapy (31.4%). No well-defined lesions were observed (p = 0.34%). CONCLUSION: It was possible to establish a protocol for evaluation of MM lesions in CBCT images and to identify that when evaluated three-dimensional, lesions tend to be poorly defined and have no pattern of description, as described in two-dimensional "punched-out".


Assuntos
Mieloma Múltiplo , Tomografia Computadorizada de Feixe Cônico , Humanos , Mandíbula/diagnóstico por imagem , Maxila , Mieloma Múltiplo/diagnóstico por imagem , Estudos Retrospectivos
5.
Rev. cir. traumatol. buco-maxilo-fac ; 10(3): 91-96, jul.-set. 2010.
Artigo em Inglês | LILACS-Express | LILACS | ID: lil-792103

RESUMO

OBJECTIVE: To identify the prevalence of hemangiomas in children born at Amaury de Medeiros Integrated Health Center between 1998 and 2008 and evaluate the characteristics of the children with this malformation. STUDY DESIGN: The identification of hemangiomas by examining the record cards of the newly-born at the maternity hospital, noting the location of the lesion(s), child's gender and weight, prematurity, Apgar score and any additional malformations. RESULTS: 68 children with hemangioma were identified, of whom 38 were girls. Regarding weight at birth, 58 of the newborns displayed adequate weight, 08 low weight, 1 very low weight and 1 extremely low weight. Two babies were born pre-term and sixty-six were born at term. The mean Apgar score was 8 with 62/91.2% of the babies presenting a normal Apgar score, 5/7.3% slight asphyxia and 1/1.5% moderate asphyxia. As to location, 61/89.7% presented hemangioma in the head and neck region and 6/8.8% in other parts of the body. The location was not recorded for 1 child. CONCLUSIONS: Female babies were the most affected. Children who develop this malformation may have been born at term with a normal Apgar score and adequate weight. Most of the newborns showed isolated lesions on the head and neck. Complementary examinations should be requested as soon as a hemangioma is identified, since cell proliferation may affect the newborn's deep organs.


OBJETIVO: Identificar a prevalência de hemangiomas em crianças nascidas no Centro Integrado de Saúde Amaury de Medeiros entre os anos de 1998 e 2008, bem como observar as características das crianças que apresentam essa malformação. DESENHO DO ESTUDO: Identificar hemangiomas através da análise dos prontuários de recém-nascidos da maternidade, bem como sua localização, gênero da criança, peso ao nascimento, APGAR e outras malformações associadas. RESULTADOS: 68 recém-nascidos foram identificados; 38 meninas. Considerando o peso ao nascimento, 58 crianças apresentaram peso adequado, 08 crianças baixo peso, 01 peso muito baixo e 01 peso extremamente baixo. Sessenta e seis bebês nasceram a termo, frente a dois que nasceram prematuros. O escore médio do APGAR foi de 8 com 62/91.2% dos bebês exibindo APGAR normal, 05/7.3% exibindo asfixia leve, 01/1.5% asfixia moderada. Nenhuma criança exibiu asfixia grave. Em relação à localização, 61/89.7% dos recém-nascidos apresentavam hemangiomas na região de cabeça e pescoço, 06/8.8% exibiram hemangiomas em outras partes do corpo. Em 01 recém-nascido a localização do hemangioma não foi registrada. CONCLUSÕES: O gênero feminino mostrou-se mais afetado por hemangiomas. Crianças que desenvolvem essa malformação podem nascer a termo, exibindo APGAR normal e com peso adequado. A maioria dos recém-nascidos apresentou lesões isoladas e em região de cabeça e pescoço. Exames complementares devem ser solicitados no momento em que forem identificados hemangiomas visíveis para se detectar possíveis lesões de acometimento em órgãos internos.

6.
Rev. cir. traumatol. buco-maxilo-fac ; 5(1): 15-20, jan.-mar. 2005.
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-872930

RESUMO

O 2-octil-cianoacrilato tem sido utilizado em diversos campos das especialidades cirúrgicas como adesivo no fechamento de retalhos gengivais e em lacerações mucosas e cutâneas, capeamento pulpar em restaurações dentárias com sucesso e aceitabilidade, além de apresentar uma ótima resposta imunológica. O Nylon, dentre os fios de sutura convencionais, é o que apresenta melhor resposta biológica, cicatricial e capacidade de coaptação de bordos de uma ferida incisa. Tendo em vista as necessidades estéticas, o cianoacrilato tem sido aplicado com resultados satisfatórios, quando comparado às suturas com o fio de Nylon, pois apresenta melhor capacidade de coaptação dos bordos de uma lesão de pele, menor cicatriz residual e biocompatibilidade, estando limitado, pois, a zonas de baixa tensão tecidual. Frente a estas considerações, este trabalho detém-se em desenvolver um estudo comparativo entre o 2-octil-cianoacrilato e o fio de sutura de Nylon, haja vista as peculiaridades, nível de cicatrização, baixa zona de tensão tecidual e estética.


Assuntos
Materiais Biocompatíveis , Cianoacrilatos , Técnicas de Sutura
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