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Sci Rep ; 8(1): 17829, 2018 12 13.
Artigo em Inglês | MEDLINE | ID: mdl-30546024


Precise prevalence of atrial fibrillation (AF) and the associated risk factors in southern China are rarely reported. This large population-based follow-up study, the Guangzhou Heart Study, was conducted from 2015 to 2017 to fill up this gap. Permanent residents aged 35 years and above in Guangzhou city were enrolled and demographic factors of participants were collected by a structured questionnaire. Examinations of physical, electrocardiographic and biochemical indicators were performed following a standard operation procedure designed prior to the field investigation. Descriptive statistics were used to evaluate basic characteristics of the study participants, and multivariate logistic regression model was performed to assess the AF prevalence-related factors. The detailed study design, the baseline characteristics and the prevalence of AF were reported here. In total, 12,013 residents were enrolled, and the percentage of participants from rural and urban areas was 53.92% and 46.08%, respectively. In total, 90.57% participants aged 40-79 years old and the proportion of women was more than men (64.98% vs. 35.02%). Overall, the prevalence of AF among the participants was 1.46%. Increasing age, male sex and widowed marital status were associated with higher AF prevalence (P-value < 0.05). The prevalence of AF increased with age and climbed to approximately 5% in residents aged 80 years and over. Residents with abnormal higher blood level of total cholesterol tended to have a lower AF prevalence but a higher prevalence of AF was observed in female participants with lower level of high density lipoprotein cholesterol land higher level uric acid (all P-value < 0.05). Personal illness such as hypertension, diabetes mellitus, dyslipidemia, myocardial infarction, heart failure, stroke and transient ischemic were significantly linked to the attack of AF (all P-value < 0.05). This study will be rich resource for investigating environmental exposure and individual genetic diathesis of AF and other common cardiovascular diseases in Chinese population.

Fibrilação Atrial/epidemiologia , Modelos Biológicos , População Rural , População Urbana , Adulto , Fatores Etários , Idoso , Fibrilação Atrial/fisiopatologia , China/epidemiologia , Feminino , Humanos , Pessoa de Meia-Idade , Prevalência , Fatores Sexuais
Water Res ; 108: 240-249, 2017 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-27863738


Gravity-driven membrane (GDM) filtration is a promising decentralized drinking water treatment process. To improve the performance of GDM system, a thin layer of adsorbent was pre-deposited on the membrane surface prior to filtration (adsorbent-laden GDM system). The tested adsorbents include powdered activated carbon (PAC) and anion exchange resin (AER), and an unmodified GDM system and a SiO2-laden GDM system were used as controls. In the adsorbent-laden GDM systems, the adsorption of the PAC and AER increased the removal efficiency of natural organic matter by 7.2-43.5% and microcystin-LR, atrazine, and bisphenol A by 7.9-81.2%. The presence of adsorbent particles increased the amount of microorganisms in the cake layer and therefore increased the removal efficiency of assimilable organic matter (AOC) by 20.1-34.4%. In the adsorbent-laden GDM systems, the physically irrecoverable fouling decreased because of the reduction in membrane foulants by the adsorbent layer. However, the presence of adsorbent particles in the cake layer counteracted this effect and increased the physically recoverable fouling. Consequently, the pre-deposited adsorbent layers had only a limited effect on the stabilized flux (2.26-2.65 L/m2 h). A bilayer structure was found in the cake layer of the adsorbent-laden GDM systems via scanning electron microscopy (SEM), and the cake layer was looser in the presence of adsorbent particles. These results demonstrate that pre-depositing a thin layer of adsorbents on the membrane surface of the GDM system can significantly improve the quality of the permeate without decreasing the stabilized flux.

Membranas Artificiais , Dióxido de Silício , Filtração , Gravitação , Purificação da Água
Acta Crystallogr Sect E Struct Rep Online ; 69(Pt 11): o1699, 2013 Oct 23.
Artigo em Inglês | MEDLINE | ID: mdl-24454125


In the title compound, C11H9FN2O2S, the 2-sulfanylideneimidazolidin-4-one moiety is essentially planar, with a maximum deviation of 0.0183 (14) Å. The mean plane of this moiety is approximately coplanar with the attached acetyl group and perpendicular to the benzene ring, making dihedral angles of 9.70 (14) and 86.70 (6)°, respectively. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds between the amide NH and acetyl C=O groups, forming a C(6) chain along the a-axis direction.