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OBJECTIVE: A pressure injury (PI) is a localised area of damage to the skin and/or underlying soft tissue as a result of a sustained mechanical loading. There are three key aetiological mechanisms to PI formation-direct cell deformation, inflammatory oedema and ischaemic damage-which are typically activated sequentially to drive a spiral of injury. This article discusses the role of the perioperative prone position as a rational approach to reducing the recurrence of pelvic PI after reconstructive surgery. METHOD: Patients with deep PI in the pelvic region, who were operated on from 2011 to 2019, were retrospectively evaluated. The protocol of care included training in the prone position, followed by maintenance of the prone position for 4-6 weeks postoperatively. The reconstruction was performed with fasciocutaneous and myocutaneous local or regional flaps. RESULTS: The study evaluated a total of 26 patients. The rate of recurrence of PIs was 15.4% (4/26) in the mean follow-up of 54 months. Regarding postoperative complications, four cases of partial dehiscence of the suture occurred. CONCLUSION: This perioperative protocol of maintaining a prone position seems to be safe for the patient, and it can be used to prevent or reduce the recurrence of deep PIs on the pelvic region after reconstructive surgery.
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Retalho Perfurante , Procedimentos de Cirurgia Plástica , Úlcera por Pressão , Humanos , Pelve , Úlcera por Pressão/prevenção & controle , Úlcera por Pressão/cirurgia , Decúbito Ventral , Recidiva , Estudos Retrospectivos , Resultado do TratamentoRESUMO
OBJETIVO: Não existe na literatura consenso indicando o melhor índice mortalidade a ser aplicado para pacientes vítimas de grandes queimaduras. Contudo, os índices de gravidade podem determinar o quadro apresentado pelo paciente, além de avaliar a probabilidade de mortalidade e morbidade a partir do quadro patológico, possibilitando uma melhor compreensão sobre a gravidade da doença e efetividade do tratamento. O objetivo é avaliar se o índice de gravidade clínica fornecido por três escalas de prognóstico (LODS, APACHE II e Charlson) reflete a situação clínica dos pacientes nas primeiras 24 horas posteriores a sua admissão na UTI de queimados. MÉTODO: Trata-se de um estudo documental com análise retrospectiva utilizando dados de 225 pacientes internados em UTI especializada em tratamentos de grandes queimados. Os valores registrados no prontuário nas primeiras 24 horas de internação foram aplicados nos escores LODS, APACHE II e índice de comorbidade de Charlson. Os pacientes foram divididos em grupo 1 (alta, 229 pacientes) e grupo 2 (óbito, 26 pacientes). RESULTADOS: Como resultado, foi obtida diferença estatística entre os dois grupos no escore de LODS e APACHE II, havendo uma média de pontuação superior no grupo 2. Também houve diferença estatística significante em relação aos parâmetros renais e pulmonares no escore de LODS, predição da mortalidade do escore APACHE II e superfície corporal queimada. CONCLUSÕES: Este estudo indica que a porcentagem de superfície corporal queimada, a função pulmonar e renal são preditores significantes de morte para pacientes queimados. Os índices calculados pelo APACHE II e o LODS se mostraram úteis para uso junto a esta população.
OBJECTIVE: There is no consensus in the literature indicating the best mortality rate to be applied to patients suffering from major burns. However, the severity indexes can determine the condition presented by the patient, in addition to evaluating the probability of mortality and morbidity from the pathological condition, allowing a better understanding of the severity of the disease and the effectiveness of the treatment. The aim is to assess whether the clinical severity index provided by three prognostic scales (LODS, APACHE II and Charlson) reflects the clinical situation of patients in the first 24 hours after their admission to the burn ICU. METHODS: This is a study with a retrospective analysis using data from 225 patients admitted to an ICU specializing in the treatment of major burns. The values recorded in the medical records in the first 24 hours of hospitalization were applied to the LODS, APACHE II and Charlson comorbidity index scores. Patients were divided into group 1 (discharge, 229 patients) and group 2 (death, 26 patients). RESULTS: As a result, a statistical difference was obtained between the two groups in the LODS and APACHE II scores, with an average of higher scores in group 2. There was also a statistically significant difference in relation to renal and pulmonary parameters in the LODS score, predicting the mortality of the APACHE II score and burned body surface. CONCLUSIONS: This study indicates that the percentage of body surface burned, lung and kidney function are significant predictors of death for burn patients. The indices calculated by APACHE II and the LODS proved to be useful for use with this population.
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Objetivo: identificar o nível de conhecimento de enfermeiros sobre a avaliação, prevenção e classificação de lesões por pressão em um hospital do Rio de Janeiro. Métodos: Trata-se de um estudo do quantitativo com delineamento descritivo-exploratório. Os dados foram coletados sem a realização de qualquer tipo de orientação ou treinamento prévio dos profissionais sobre lesão por pressão (LPP). Para seu desenvolvimento, foi utilizado o Pressure Ulcer Pieper Knowledge Test (PUKT), que é composto de 41 questões sobre avaliação, classificação e prevenção de lesões por pressão. Destas, 8 questões referem-se a avaliação e classificação da LPP e 33 questões sobre prevenção. Resultados: Participaram 102 enfermeiros, sendo 71 do sexo feminino e 31 do sexo masculino. A predominância de idade dos participantes foi de 30 a 39 anos. Quanto ao tempo de formado a maioria possui entre 2 a 5 anos de conclusão de curso e formação em Latu senso. Em relação aos resultados globais do teste, 70% (68.63%) dos enfermeiros acertaram menos de 70 % das questões, indicando um déficit de conhecimento na área. Conclusão: Diante dos resultados, identifica-se um déficit no conhecimento sobre a avaliação, classificação e prevenção de LPP, indicando a necessidade da educação permanente para atualização dos profissionais de enfermagem
Objective: to identify the level of nurses' knowledge on evaluation, prevention and classification of pressure ulcers in a hospital in Rio de Janeiro. Methods: This is a quantitative study with a descriptive-exploratory design. The data were collected without conducting any kind of orientation or training on pressure ulcer (LPP). For its development, the Pressure Ulcer Pieper Knowledge Test (PUKT) was used, which is composed of 41 questions about evaluation, classification and prevention of Pressure Ulcers. Of these, 8 questions refer to the evaluation and classification of the UPP and 33 questions are about prevention. Results: 102 nurses participated, 71 female and 31 male. The participants' predominance of age was 30 to 39 years. As for the time of training, the majority has between 2 to 5 years of conclusion of course and the majority has formation in Latu senso. Regarding the overall results of the test, 70% (68.63%) of nurses scored less than 70% of the questions, indicating a lack of knowledge in the area. Conclusion: In view of the results, a deficit in the knowledge about the evaluation, classification and prevention of LPP is identified, indicating the need for permanent education to update and improve nursing professionals
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Humanos , Enfermagem , Classificação , Conhecimento , Úlcera por PressãoRESUMO
BACKGROUND: Patients with longstanding facial paralysis often exhibit synkinesis. Few reports describe the prevalence and factors related to the development of synkinesis after facial paralysis. Botulinum toxin type A injection is an important adjunct treatment for facial paralysis-induced asymmetry and synkinesis. The authors assessed the clinical and epidemiologic characteristics of patients with sequelae of facial paralysis treated with botulinum toxin type A injections to evaluate the prevalence of synkinesis and related factors. METHODS: A total of 353 patients (age, 4 to 84 years; 245 female patients) with longstanding facial paralysis underwent 2312 botulinum toxin type A injections during an 11-year follow-up. Doses used over the years, previous treatments (electrical stimulation, operations), and how they correlated to postparalysis and postreanimation synkinesis were analyzed. RESULTS: There was a significant association between cause and surgery. Most patients with facial paralysis caused by a congenital defect, trauma, or a tumor underwent reanimation. There were no sex- or synkinesis-related differences in the doses used, but the doses were higher in the reanimation group than in the no-surgery group. Synkinesis was found in 196 patients; 148 (41.9 percent) presented with postparalysis synkinesis (oro-ocular, oculo-oral) and 58 (16.4 percent) presented with postreanimation synkinesis. Ten patients presented with both types. CONCLUSIONS: This study determined the high prevalence (55.5 percent) of synkinesis in patients with longstanding facial paralysis. Postparalysis synkinesis was positively associated with infectious and idiopathic causes, electrical stimulation, facial nerve decompression, and no requirement for surgery. Postreanimation synkinesis was present in 28.2 percent of reanimated patients and was significantly associated with microsurgical flaps, transfacial nerve grafting, masseteric-facial anastomosis, and temporalis muscle transfers.
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Toxinas Botulínicas Tipo A/uso terapêutico , Assimetria Facial/tratamento farmacológico , Fármacos Neuromusculares/uso terapêutico , Sincinesia/tratamento farmacológico , Sincinesia/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Assimetria Facial/etiologia , Paralisia Facial/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Sincinesia/etiologia , Fatores de Tempo , Adulto JovemRESUMO
BACKGROUND: Botulinum toxin A injection into the nonparalyzed side is used to treat asymmetry resulting from facial palsy. OnabotulinumtoxinA and abobotulinumtoxinA units are not equivalent. The authors compared the conversion ratio of 1:3 in patients with facial palsy. METHODS: Fifty-five patients (age, 16 to 67 years; 43 women) with longstanding facial palsy were randomly treated with either onabotulinumtoxinA (n = 25) or abobotulinumtoxinA (n = 30) injections into the nonparalyzed side. Adverse effects, facial symmetry, subjective satisfaction, and Facial Disability Index were assessed after 1 and 6 months. RESULTS: The incidence of adverse effects was higher with abobotulinumtoxinA (93.3 percent versus 64.0 percent; p = 0.007). Clinical scores of the nonparalyzed side decreased after 1 month and increased again at 6 months, with no between-group differences. Scores of the paralyzed side were lower in the onabotulinumtoxinA group before treatment, but similar in both groups thereafter. The paralyzed side scores increased after 1 month, and at 6 months were still higher than the pretreatment scores in both groups. Subjective assessment improved at all time points compared with pretreatment scores and differed between the two groups only at 1 month, when the abobotulinumtoxinA group was a bit too paralyzed. The physical function and social/well-being function subscales of the Facial Disability Index did not differ between the two groups. CONCLUSIONS: Both toxins efficiently reduced asymmetry in patients with facial palsy. Adverse effects were higher with abobotulinumtoxinA at an equivalence ratio of 1:3. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II.
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Toxinas Botulínicas Tipo A/administração & dosagem , Assimetria Facial/tratamento farmacológico , Assimetria Facial/etiologia , Paralisia Facial/complicações , Adolescente , Adulto , Idoso , Toxinas Botulínicas Tipo A/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Tempo , Resultado do Tratamento , Adulto JovemRESUMO
INTRODUÇÃO: A braquioplastia trata as deformidades dos membros superiores. A toracoplastia lateral visa o tratamento do torso superior. As braquioplastias, toracoplastias e também as braquiotoracoplastias em Z têm sido utilizadas no Hospital Estadual de Sapopemba no tratamento das deformidades dos membros superiores e terço superior do tórax. Objetivo: Propõe-se descrever as modificações na técnica cirúrgica resultando na braquiotoracoplastia em Z e analisar a casuística e os resultados obtidos, no tratamento das deformidades da região lateral do tórax. MÉTODO: Foram submetidos à braquiotoracoplastia e toracoplastia lateral 31 pacientes. A demarcação foi feita em posição ortostática, e os membros superiores abduzidos em 90o. Iniciou-se pela demarcação da braquioplastia, em duplo fuso, prolongando-se de maneira modificada a demarcação, seguindo pela linha axilar anterior em direção ao sulco inframamário em forma de Z. RESULTADOS: Todos os pacientes referiram melhora do contorno da região e não houve queixas quanto ao posicionamento da cicatriz. DISCUSSÃO: O procedimento da braquiotoracoplastia em Z atual consiste em estender a linha de incisão da face medial do braço, passando proximalmente à axila e continuando pela linha axilar média até o sulco mamário. Ocorreu a melhora do contorno da região dorsal e das dobras cutâneas da região torácica lateral. CONCLUSÃO: A braquiotoracoplastia em Z e a toracoplastia lateral têm a grande vantagem de eliminar a cicatriz circunferencial no torso superior, promovendo a melhoria do contorno dessa região por meio da ressecção cutânea tanto no sentido craniocaudal, como anteroposterior.
INTRODUCTION: Brachioplasty treats deformities of the upper limbs. Lateral thoracoplasty treats the upper torso. Brachioplasties, thoracoplasties, and brachiothoracoplasties have been performed with Z-plasty for deformities of the upper limbs and upper third of the chest, in the Sapopemba State Hospital. Objective: We describe modifications of surgical technique for the performance of Z brachiothoracoplasty, and evaluate the results of treatment of deformities of the lateral chest. METHOD: Thirty-one Patients underwent brachiothoracoplasty and lateral thoracoplasty. The demarcation was made with the patient upright, and the upper limbs abducted at 90º. Marking for brachioplasty was performed using a double-ellipse, to lengthen the modified demarcation along the anterior axillary line toward the inframammary crease in a Z shape. RESULTS: All patients reported an improvement in the contour of the region, and there were no complaints regarding the positioning of the scar. DISCUSSION: Z brachiothoracoplasty consists of extending the incision line on the medial aspect of the arm, passing proximally to the axilla, and continuing through the midaxillary line to the inframammary crease. There was an improvement in the contour of the dorsal region and the skin folds of the lateral thoracic region. CONCLUSION: Z brachiothoracoplasty and lateral thoracoplasty have the great advantage of eliminating a circumferential scar on the upper torso, thereby improving the contour of the region through skin resection in both the craniocaudal and anteroposterior directions.
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Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , História do Século XXI , Toracoplastia , Redução de Peso , Extremidade Superior , Parede Torácica , Deformidades Congênitas das Extremidades Superiores , Difusão de Inovações , Cirurgia Bariátrica , Obesidade , Toracoplastia/métodos , Extremidade Superior/cirurgia , Parede Torácica/cirurgia , Parede Torácica/patologia , Deformidades Congênitas das Extremidades Superiores/cirurgia , Deformidades Congênitas das Extremidades Superiores/patologia , Cirurgia Bariátrica/métodos , Obesidade/cirurgiaRESUMO
Introdução: O espasmo hemifacial (EHF) caracteriza-se por movimento tônico-clônico involuntário da musculatura de uma hemiface. O tratamento tem sido realizado com aplicação de toxina botulínica (TxB). A aplicação unilateral classicamente descrita resulta em assimetria semelhante à paralisia facial. O objetivo desse trabalho foi normatizar o tratamento do EHF bilateralmente com TxB, a fim de prevenir a ocorrência de assimetria facial iatrogênica. Método: Foram analisadas 66 aplicações em 15 pacientes, seguindo o protocolo do serviço para paralisia facial, acrescentado de pontos pré-tarsais no lado com EHF. Foi feita dose complementar na reavaliação após 15 dias nos pacientes que apresentavam algum grau residual de espasmo ou assimetria, buscando-se a dose necessária para alcançar controle satisfatório do espasmo sem causar assimetria facial. Resultados: A dose média total foi 20,2 U do lado não acometido e 28,4 U do lado acometido, totalizando 48,6 U por aplicação. Houve diferença significante entre as hemifaces na dose para os músculos zigomático, orbicular da boca e orbicular dos olhos. Conclusões: A técnica proposta de aplicação bilateral de TxB controlou adequadamente o EHF e evitou assimetria iatrogênica. Como regra geral, a aplicação deve ser feita na proporção de 1:1,5 U no orbicular dos olhos (porção lateral) e 1:2 U no orbicular da boca. Nos demais músculos, a dose nos dois lados deve ser a mesma, realizando-se dose de reforço em 15 dias caso permaneça algum grau de espasmo. O único local com pontos exclusivos do lado acometido é a região pré-tarsal do músculo orbicular do olho.
Introduction: Hemifacial spasm (HFS) is characterized by the involuntary tonic-clonic movement of the muscles of the hemiface. It is usually treated with botulinum toxin (BTX). The classically described unilateral application of BTX results in an asymmetry similar to facial paralysis. The aim of this study was to standardize the treatment of HFS by applying BTX bilaterally to prevent the occurrence of iatrogenic facial asymmetry. Methods: The outcomes of 66 applications in 15 patients were analyzed according to the protocol of the facial paralysis service, to which pretarsal sites were added on the HFS side. On reassessment 15 days later, a complementary dose was administered to patients who exhibited some residual degree of spasm or asymmetry with the aim of determining the dose required to achieve satisfactory spasm control without causing facial asymmetry. Results: The total mean dose was 20.2 U at the contralateral side and 28.4 U at the spasm side (a total dose of 48.6 U per application). There was a significant difference between the doses applied to the zygomaticus, orbicularis oris, and orbicular oculi muscles on each hemiface . Conclusions: The proposed bilateral BTX application technique was effective in controlling HFS and prevented iatrogenic asymmetry. In general, application should be performed at a ratio of 1:1.5 U in the orbicularis oculi (lateral portion) and 1:2 U in the orbicularis oris. In the remaining muscles, the same dose should be administered on both sides and an additional dose can be applied 15 days later if some degree of spasm is present. The pretarsal region of the orbicularis oculi muscle is the only area for which BTX application on the healthy side is unnecessary.
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Humanos , Masculino , Feminino , Pessoa de Meia-Idade , História do Século XXI , Estudos Prospectivos , Toxinas Botulínicas Tipo A , Espasmo Hemifacial , Guias como Assunto , Estudo de Avaliação , Assimetria Facial , Ossos Faciais , Doenças do Nervo Facial , Paralisia Facial , Toxinas Botulínicas Tipo A/uso terapêutico , Toxinas Botulínicas Tipo A/farmacologia , Espasmo Hemifacial/cirurgia , Espasmo Hemifacial/patologia , Guias como Assunto/métodos , Assimetria Facial/patologia , Assimetria Facial/terapia , Ossos Faciais/anormalidades , Ossos Faciais/patologia , Doenças do Nervo Facial/patologia , Paralisia Facial/patologiaRESUMO
SUMMARY: Pseudoxanthoma elasticum (PE) is a rare genetic disease characterized by calcification and fragmentation of elastic fibers of the skin, retina, and cardiovascular system. We report a case of PE in which fractional carbon dioxide laser treatment was successfully used to achieve improvement of the cervical skin with 2-year follow-up, in a patient with Fitzpatrick skin type IV. After the fifth session, the patient presented with a local herpes infection. The postlaser reaction of the PE skin was similar to that of the normal skin, in terms of the duration of redness, pain, swelling, and duration of crusting. The overall cosmetic result was satisfactory, with improvement in skin texture, irregularity, volume, and distensibility. The herpetic infection reinforces the value of antiviral prophylaxis during laser treatment of extrafacial areas.
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INTRODUÇÃO: A utilização de implante mamário é a forma de reconstrução de mama mais comumente realizada. Apesar de suas vantagens, a infecção do implante, seja este expansor tecidual ou prótese mamária, pode ser um problema significativo, incluindo a necessidade de sua retirada. O objetivo deste trabalho é avaliar o índice de infecção de implantes mamários utilizados na reconstrução de mama de pacientes operadas no Instituto do Câncer do Estado de São Paulo (ICESP), bem como sua correlação com aspectos clínicos, oncológicos e cirúrgicos. PACIENTES E MÉTODOS: Estudo retrospectivo de 120 pacientes submetidas à reconstrução mamária com implante mamário no ICESP, no período de fevereiro de 2009 a março de 2010. RESULTADOS: O índice de infecção foi de 24,3% e esteve relacionado estatisticamente a reconstrução imediata (88,9%), diabetes mellitus (25%), IMC acima de 30 (52,8%), HAS (52,8%) e sofrimento de pele da mastectomia (27,8%). Nota-se que 44% dos implantes infectados foram retirados, sendo a maioria expansores colocados em reconstrução imediata. CONCLUSÕES: A reconstrução mamária com implante é uma forma segura e eficaz de tratamento. Deve-se, entretanto, estar atento aos subgrupos de pacientes mais propensas ao desenvolvimento de infecção, para otimizar a sua prevenção e atentar ao seu tratamento precoce.
INTRODUCTION: Placement of breast implants is the most commonly used form of breast reconstruction. Despite its advantages, infection of the implant, either in the tissue expander or mammary prosthesis, can be a significant problem, including the need to remove it. The objective of this work is to evaluate the infection rate of breast implants used for breast reconstruction in patients submitted to surgery at the Cancer Institute of the State of São Paulo (ICESP), as well as its correlation with clinical, oncological, and surgical factors. PATIENTS AND METHODS: This is a retrospective study on 120 patients submitted to breast reconstruction with breast implants at the ICESP from February 2009 to March 2010. RESULTS: The infection rate (24.3%) was statistically related to immediate reconstruction (88.9%), diabetes mellitus (25%), body mass index >30 (52.8%), systemic arterial hypertension (52.8%), and skin injury due to mastectomy (27.8%). Of the infected implants, 44% were removed, most of which were expanders placed during immediate reconstruction. CONCLUSIONS: Breast reconstruction with implants is the safest and most effective form of treatment. However, consideration should be given to patients who are prone to the development of infection, in order to optimize its prevention and attempt to perform its treatment at an early stage.
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Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , História do Século XXI , Mama , Neoplasias da Mama , Dispositivos para Expansão de Tecidos , Estudos Retrospectivos , Infecções Relacionadas à Prótese , Implantes de Mama , Procedimentos de Cirurgia Plástica , Glândulas Mamárias Humanas , Mama/cirurgia , Neoplasias da Mama/cirurgia , Dispositivos para Expansão de Tecidos/normas , Infecções Relacionadas à Prótese/cirurgia , Infecções Relacionadas à Prótese/complicações , Implantes de Mama/normas , Procedimentos de Cirurgia Plástica/métodos , Glândulas Mamárias Humanas/cirurgiaRESUMO
PURPOSE: To investigate the reproducibility of the experimental model of face allotransplantation in rats in Brazil. METHODS: Eighteen rats were operated, nine-nine donors recipients. Animals underwent transplantation of the left hemiface, with periorbital and scalp. Transplants were made from donor Wistar rats to recipients Lewis rats. Flaps were based on the common carotid artery and the external jugular vein of the donor animal and the anastomosis in the recipient area was performed in common carotid artery (end-to-side) and in external jugular vein (end-to-end). RESULTS: Of the nine recipient animals operated, six survived and three progressed to death in the first days after surgery (survival rate = 67%). The mean time of the procedure was 252 minutes and the mean time of flap ischemia was 95 minutes. The five surviving animals were sacrificed at 14 days, in good general condition and without signs of tissue rejection. CONCLUSIONS: The experimental model of face allotransplantation in rats is reproducible in our midst. Duration of surgery, time of flap ischemia, animal survival rate and complications observed were similar to those described in the literature.
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Transplante de Face/métodos , Modelos Teóricos , Retalhos Cirúrgicos/irrigação sanguínea , Anastomose Cirúrgica/métodos , Animais , Brasil , Artéria Carótida Primitiva/cirurgia , Face , Transplante de Face/efeitos adversos , Rejeição de Enxerto , Sobrevivência de Enxerto , Veias Jugulares/cirurgia , Duração da Cirurgia , Ratos Endogâmicos Lew , Ratos Wistar , Reprodutibilidade dos Testes , Couro Cabeludo/transplante , Transplante HomólogoRESUMO
PURPOSE: To investigate the reproducibility of the experimental model of face allotransplantation in rats in Brazil. METHODS: Eighteen rats were operated, nine-nine donors recipients. Animals underwent transplantation of the left hemiface, with periorbital and scalp. Transplants were made from donor Wistar rats to recipients Lewis rats. Flaps were based on the common carotid artery and the external jugular vein of the donor animal and the anastomosis in the recipient area was performed in common carotid artery (end-to-side) and in external jugular vein (end-to-end). RESULTS: Of the nine recipient animals operated, six survived and three progressed to death in the first days after surgery (survival rate = 67%). The mean time of the procedure was 252 minutes and the mean time of flap ischemia was 95 minutes. The five surviving animals were sacrificed at 14 days, in good general condition and without signs of tissue rejection. CONCLUSIONS: The experimental model of face allotransplantation in rats is reproducible in our midst. Duration of surgery, time of flap ischemia, animal survival rate and complications observed were similar to those described in the literature. .
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Animais , Transplante de Face/métodos , Modelos Teóricos , Retalhos Cirúrgicos/irrigação sanguínea , Anastomose Cirúrgica/métodos , Brasil , Artéria Carótida Primitiva/cirurgia , Face , Transplante de Face/efeitos adversos , Rejeição de Enxerto , Sobrevivência de Enxerto , Veias Jugulares/cirurgia , Duração da Cirurgia , Ratos Endogâmicos Lew , Ratos Wistar , Reprodutibilidade dos Testes , Couro Cabeludo/transplante , Transplante HomólogoRESUMO
BACKGROUND: The lateral thoracic flap was first studied in the mid-1970s but its use has been limited because of pedicle anatomical variations. However, after the development of lymph node transfer surgery, the axilla/upper lateral thorax presented as a promising donor area. Through a detailed anatomical study, the lateral thoracic flap was evaluated regarding its vascularization and composition. Later, it was used for pedicle and free flap reconstructions. METHODS: A total of 40 flaps were dissected in fresh cadavers and the characteristics of the lateral thoracic pedicle and its relationship to the upper lateral thoracic axillary lymph nodes (LTLN) were analyzed. We performed six pedicle flap reconstructions around the shoulder area and a free lymph node transfer for lower limb lymphedema. RESULTS: In the cadaveric dissections, the lateral thoracic pedicle branched off the axillary vessels and was found to be a primary level I axillary lymph node irrigator before reaching the skin. The cutaneous portion of the artery was present in 87.5% of the dissections. Arterial caliber was an average of 1.3 and venous, 2.6 mm. Five to seven lymph nodes were isolated with each pedicle and a lymph fasciocutaneous flap could be designed. In seven clinical cases, all of the flaps survived. Functioning lymph nodes were visualized on lymphoscintigraphy after their transfer to the ankle. Donor area had an inconspicuous evolution. CONCLUSION: Lateral thoracic flap is a feasible flap with low donor area morbidity in a concealed region that can be harvested with upper LTLN for transplantation.
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Linfonodos/transplante , Retalhos Cirúrgicos/irrigação sanguínea , Artérias Torácicas/transplante , Adulto , Cadáver , Feminino , Humanos , Linfonodos/irrigação sanguínea , Masculino , Pessoa de Meia-Idade , Adulto JovemRESUMO
INTRODUCTION: To characterize the evolution of clinical and physiological variables in severe adult burn patients admitted to a Brazilian burn ICU, we hypothesized that characteristics of survivors are different from non-survivors after ICU admission. METHODS: A five-year observational study was carried out. The clinical characteristics, physiological variables, and outcomes were collected during this period. RESULTS: A total of 163 patients required ICU support and were analyzed. Median age was 34 [25,47] years. Total burn surface area (TBSA) was 29 [18,43]%, and hospital mortality rate was 42%. Lethal burn area at which fifty percent of patients died (LA50%) was 36.5%. Median SAPS3 was 41 [34,54]. Factors associated with hospital mortality were analyzed in three steps, the first incorporated ICU admission data, the second incorporated first day ICU data, and the third incorporated data from the first week of an ICU stay. We found a significant association between hospital mortality and SAPS3 [OR(95%CI)=1.114(1.062-1.168)], TBSA [OR(95%CI)=1.043(1.010-1.076)], suicide attempts [OR(95%CI)=8.126(2.284-28.907)], and cumulative fluid balance per liter within the first week [OR(95%CI)=1.090(1.030-1.154)]. Inhalation injury was present in 45% of patients, and it was not significantly associated with hospital mortality. CONCLUSIONS: In this study of an ICU in a developing country, the mortality rate of critically ill burn patients was high and the TBSA was an independent risk factor for death. SAPS3 at admission and cumulative fluid balance in the first seven days, were also associated with unfavorable outcomes. The implementation of judicious fluid management after an acute resuscitation phase may help to improve outcomes in this scenario.
Assuntos
Queimaduras/mortalidade , Unidades de Terapia Intensiva/estatística & dados numéricos , Adulto , Idoso , Brasil/epidemiologia , Queimaduras/patologia , Queimaduras/fisiopatologia , Estado Terminal , Feminino , Indicadores Básicos de Saúde , Mortalidade Hospitalar , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Índice de Gravidade de Doença , Equilíbrio Hidroeletrolítico/fisiologiaRESUMO
Introdução: Feridas em pés são muito frequentes e requerem abordagem multidisciplinar para a sua prevenção, tratamento e reabilitação. Quando acometem o calcâneo, oferecem dificuldade ainda maior e podem apresentar complicação com a ocorrência de osteomielite. Debridamento de tecido desvitalizado e antibioticoterapia são etapas obrigatórias para o tratamento. Na reconstrução, retalhos locais ou livres são necessários. Porém, nem todos os pacientes, devido a condições sistêmicas ou de vascularização local, são candidatos a esse tipo de reconstrução e acabam sendo submetidos a amputações. Relato de caso: Os autores relatam dois casos nos quais foram utilizadas calcanectomias subtotais para o tratamento de feridas em calcâneo. Em ambos os casos, foram evitadas as amputações.
Introduction: Feet wounds are very common and require multidisciplinary approach for prevention, treatment and rehabilitation. When involving the calcaneus, they offer even greater difficulty and may complicate with osteomyelitis. Debridement of devitalized tissue and antibiotics are important steps for treatment. For the reconstruction, local or free flaps are needed. However, not all patients, due to systemic conditions or local blood supply, are not candidates for this type of reconstruction and some times are submitted to amputations. Cases Report: The authors report two cases in which subtotals calcanectomies were used for the treatment of wounds in the calcaneus. In both cases, amputations were avoided.
Assuntos
Humanos , Masculino , Feminino , Adulto , Idoso , História do Século XXI , Osteomielite , Complicações Pós-Operatórias , Procedimentos Cirúrgicos Operatórios , Ferimentos e Lesões , Relatos de Casos , Calcâneo , Úlcera por Pressão , Antibacterianos , Osteomielite/cirurgia , Osteomielite/patologia , Complicações Pós-Operatórias/cirurgia , Complicações Pós-Operatórias/terapia , Procedimentos Cirúrgicos Operatórios/métodos , Ferimentos e Lesões/cirurgia , Ferimentos e Lesões/patologia , Calcâneo/cirurgia , Calcâneo/lesões , Calcâneo/patologia , Úlcera por Pressão/cirurgia , Úlcera por Pressão/patologia , Antibacterianos/uso terapêuticoRESUMO
BACKGROUND: Carpal tunnel syndrome (CTS) is the most common compression neuropathy of the upper limb. Close to 5% of patients with chronic renal failure who need hemodialysis present CTS. Clinical history and physical examination remain the most adequate tools for diagnosis, and there is still controversy regarding the most reliable test to complement it. Evaluation of sensory thresholds using Pressure-Specified Sensory Device (PSSD) has become an important instrumental test. METHOD: This study aimed to determine the values of pressure sensory thresholds using the PSSD before and after treatment of CTS in a special group of patients who underwent chronic hemodialysis. The PSSD incorporates a pressure transducer linked to a computer capable of measuring the cutaneous pressure thresholds referred by the patient. Two groups were compared as follows: group 1, patients with hemodialysis-related CTS; and group 2, CTS in non-hemodialysis patients. The following measurements were assessed: static one point, moving one point, static two points, and moving two points. RESULTS: There was improvement (lower thresholds) in the postoperative measurements in all parameters assessed in group 1, and improvements in all parameters except the moving one point test in group 2. CONCLUSIONS: Nerve decompression, as expected, can be considered a good treatment of CTS even in more severe cases as in those patients under hemodialysis. The PSSD tests were reliable to confirm the diagnosis and thus to indicate the decompression. It is even more beneficial to provide a comparison between preoperative and postoperative data and different causes of CTS.
Assuntos
Síndrome do Túnel Carpal/fisiopatologia , Síndrome do Túnel Carpal/cirurgia , Descompressão Cirúrgica , Falência Renal Crônica/epidemiologia , Diálise Renal , Limiar Sensorial , Adulto , Síndrome do Túnel Carpal/epidemiologia , Comorbidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Recuperação de Função FisiológicaRESUMO
Introdução: Insatisfação dos pacientes com resultado de mamoplastia redutora pode ser identificado em alguns casos, especialmente quando apresentam ptose acompanhada de flacidez excessive, estrias, e ainda, componente mamário mais gorduroso que glandular. Nesses tipos de pacientes, é muito difícil conseguir bons resultados por longo período. Implantes mamários de pequeno volume, podem ser colocados no mesmo tempo da mamoplastia redutora com o objetivo de se obter melhor forma, contorno e projeção das mamas, com maior satisfação a longo prazo. Método: No período de 1997 a 2012, duzentos e sessenta e quatro pacientes com idade entre 27e 55 anos (idade média de 38), foram submetidas à mamoplastia redutora com imediata colocação de implante mamário. Resultados: Foram obtidos resultados satisfatórios, com adequado preenchimento do pólo superior, mamas firmes e reduzida estatística de ptose pós-operatória. Foram identificados dois casos de carcinoma in sito, como achados no anátomo-patológico. Conclusão: Mastoplastia redutora associada a implantes de silicone é um procedimento seguro para casos selecionados.
INTRODUCTION: Patient dissatisfaction with reduction mammoplasty outcomes can occur, especially in cases of ptosis accompanied by excessive flaccidity, striations, and a higher fat than glandular content. In such cases, achieving long-lasting results is very difficult. Small-volume breast implants can be placed during the reduction mammoplasty with the purpose of obtaining better breast shape, contour, and projection as well as greater long-term satisfaction. METHOD: Between 1997 and 2012, 264 patients aged 27-55 years (mean, 38) underwent reduction mammoplasty with immediate placement of breast implants. RESULTS: Satisfactory results were obtained, with adequate filling of the upper pole, increased breast firmness, and statistical reduction in postoperative ptosis. Two cases of carcinoma in situ were identified in the pathological exam. CONCLUSION: Reduction mastoplasty associated with silicone implants is safe for selected cases.
Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , História do Século XXI , Complicações Pós-Operatórias , Silicones , Mama , Neoplasias da Mama , Mamoplastia , Implantes de Mama , Procedimentos de Cirurgia Plástica , Glândulas Mamárias Humanas , Estética , Hipertrofia , Complicações Pós-Operatórias/cirurgia , Complicações Pós-Operatórias/patologia , Silicones/uso terapêutico , Silicones/química , Mama/cirurgia , Mama/lesões , Neoplasias da Mama/cirurgia , Mamoplastia/efeitos adversos , Mamoplastia/métodos , Implantes de Mama/efeitos adversos , Implantes de Mama/normas , Procedimentos de Cirurgia Plástica/métodos , Glândulas Mamárias Humanas/cirurgia , Glândulas Mamárias Humanas/lesões , Hipertrofia/cirurgia , Hipertrofia/complicaçõesRESUMO
PURPOSE: To assess the viability of cultured epithelium and preserved by freezing for periods varying from one month to one year. METHODS: Samples of cultured epithelium were incubated in cryoprotectant medium (Group A), packed in aluminum envelopes and packed in polystyrene boxes. The boxes were subjected to a temperature of-70 ºC. After freezing for a period of time ranging from one to 12 months, cultured epithelial samples were assessed for their viability by vital staining (Trypan blue) and metabolic analysis based on glucose consumption and lactate production. Samples of not frozen cultured epithelium (Group B) were also tested for viability and the results obtained were used as comparison parameter for the variation of viability. RESULTS: Statistical analysis between the group A and B indicate that the mean age of the donors (p=0.51) and the culture time (p=1.18) showed no statistical difference. In 30 days we obtained 37% of the original viability of cultured epithelium, 25% at six months and one year, less than 15%. This trend was confirmed statistically with a reduction of approximately 1.8% of the original viability epithelium cultured every 30 days of storage. In the analysis by lactate production, similar results were observed. In the analysis by the glucose consumption results were not significant. The viability indices show statistically significant difference between the group A and B (p<0.0001). CONCLUSIONS: Although cryopreserved cultured epithelium showed significant reduction of viability, all samples remained viable. It was also found that the viability of cryopreserved cultured epithelial decreased as a function of storage time.
Assuntos
Criopreservação/métodos , Pele , Sobrevivência de Tecidos/fisiologia , Adulto , Aloenxertos/fisiologia , Sobrevivência Celular/fisiologia , Células Cultivadas/fisiologia , Crioprotetores/farmacologia , Meios de Cultura , Epitélio/fisiologia , Feminino , Humanos , Masculino , Valores de Referência , Reprodutibilidade dos Testes , Estatísticas não Paramétricas , Fatores de Tempo , Adulto JovemRESUMO
PURPOSE: To assess the viability of cultured epithelium and preserved by freezing for periods varying from one month to one year. METHODS: Samples of cultured epithelium were incubated in cryoprotectant medium (Group A), packed in aluminum envelopes and packed in polystyrene boxes. The boxes were subjected to a temperature of-70ºC. After freezing for a period of time ranging from one to 12 months, cultured epithelial samples were assessed for their viability by vital staining (Trypan blue) and metabolic analysis based on glucose consumption and lactate production. Samples of not frozen cultured epithelium (Group B) were also tested for viability and the results obtained were used as comparison parameter for the variation of viability. RESULTS: Statistical analysis between the group A and B indicate that the mean age of the donors (p=0.51) and the culture time (p=1.18) showed no statistical difference. In 30 days we obtained 37% of the original viability of cultured epithelium, 25% at six months and one year, less than 15%. This trend was confirmed statistically with a reduction of approximately 1.8% of the original viability epithelium cultured every 30 days of storage. In the analysis by lactate production, similar results were observed. In the analysis by the glucose consumption results were not significant. The viability indices show statistically significant difference between the group A and B (p<0.0001). CONCLUSIONS: Although cryopreserved cultured epithelium showed significant reduction of viability, all samples remained viable. It was also found that the viability of cryopreserved cultured epithelial decreased as a function of storage time.
Assuntos
Adulto , Feminino , Humanos , Masculino , Adulto Jovem , Criopreservação/métodos , Pele , Sobrevivência de Tecidos/fisiologia , Aloenxertos/fisiologia , Meios de Cultura , Sobrevivência Celular/fisiologia , Células Cultivadas/fisiologia , Crioprotetores/farmacologia , Epitélio/fisiologia , Valores de Referência , Reprodutibilidade dos Testes , Estatísticas não Paramétricas , Fatores de TempoRESUMO
BACKGROUND: Extensive bone defects are still a challenge for reconstructive surgery. Allogenic bones can be an alternative with no donor area morbidity and unlimited amount of tissue. Better results can be achieved after allogenic bone preparation and adding a vascular supply, which can be done along with flap prefabrication. The purpose of this study was to evaluate demineralized/lyophilized and deep-frozen allogenic bones used for flap prefabrication and the tissue expression of transforming growth factor ß (TGF-ß) in these bone fragments. METHODS: Fifty-six Wistar rat bone diaphyses were prepared and distributed in 4 groups: demineralized/lyophilized (experimental group 1 and control group 2) and deep freezing (experimental group 3 and control group 4). Two bone segments (one of each group) were implanted in rats to prefabricate flaps using superficial epigastric vessels (experimental groups) or only transferred as grafts (control groups). These fragments remained in their respective inguinal regions until the death that occurred at 2, 4, and 6 weeks after the operation. Semiquantitative histologic (tetracycline marking, cortical resorption, number of giant cells, and vascularization) and histomorphometrical quantitative (osteoid thickness, cortical thickness, and fibrosis thickness) analyses were performed. Transforming growth factor ß immunohistochemistry staining was also performed. RESULTS: Group 1 fragments presented an osteoid matrix on their external surface in all periods. Cartilage formation and mineralization areas were also noticed. These findings were not observed in group 3 fragments. Group 1 had more mineralization and double tetracycline marks, which were almost not seen in group 3. Cortical resorption and the number of giant cells were greater in group 3 in all periods. Vascularization and fibrosis thickness were similar in both experimental groups. Group 1 had more intense TGF-ß staining within 2 weeks of study. Nevertheless, from 4 weeks onward, group 3 presented statistically significant stronger staining. CONCLUSIONS: Although there are some differences between the preparation methods of allogenic bone, it is possible to prefabricate flaps with demineralized/lyophilized and deep-frozen bones.