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Sleep Breath ; 2021 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-33709191

RESUMO

PURPOSE: The objective of this systematic review was to answer the question: "Is there association between obstructive sleep apnea (OSA) and health-related quality of life (HRQoL) in untreated adults?" METHODS: We included observational studies that evaluated the health-related quality of life of patients with OSA vs control groups, through generic and disease-specific questionnaires. The searches were conducted in six databases: Embase, Lilacs, PsycINFO, PubMed, Scopus, and Web of Science. Additional search in the grey literature and hand search were performed, and also experts were consulted. Risk of bias was performed by using Joanna Briggs Institute Critical Appraisal Checklist for cross-sectional, cohort, and case-control studies. We analyzed the data using a narrative synthesis. The Grading of Recommendations Assessment, Development, and Evaluation evidence profile was used to verify the overall certainty of the assessed evidence. RESULTS: Nineteen studies were included for qualitative analysis. Generic questionnaires showed worse HRQoL in the OSA group compared to the control group in at least one domain of the HRQoL questionnaires. The affected domains that showed statistical and clinically relevant differences were physical functioning, physical role, pain, general health, vitality, emotional role, and mental health. The certainty of evidence assessment was very low. CONCLUSION: The available literature suggests that OSA in untreated adults is associated with worse HRQoL. However, this association seems to disappear when we consider only studies adjusted for related covariates. REGISTRATION: CRD42018114746.

3.
Am J Orthod Dentofacial Orthop ; 159(3): 352-359, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33641816

RESUMO

INTRODUCTION: The objective of this research was to compare the oropharyngeal volume and minimal cross-sectional area (MCA) changes after maxillary expansion using either the Damon system or Hyrax appliances as assessed through cone-beam computed tomography (CBCT) imaging. METHODS: Patients aged between 11 and 17 years with skeletal maxillary transverse discrepancy in need of maxillary expansion were included and allocated randomly into 1 of the 2 treatment groups, Damon or Hyrax. Patients underwent CBCT imaging at 2 time points: T1, after initial clinical evaluation before treatment, and T2, after completion of full orthodontic treatment. The CBCT data were assessed using Dolphin software (Dolphin Imaging & Management Solutions, Chatsworth, Calif). In addition, a qualitative assessment of breathing function was done using the modified Nasal Obstruction and Septoplasty Effectiveness Scale questionnaire. RESULTS: A statistically significant increase in the oropharyngeal volume (2.23 mL; P = 0.005) and MCA (29.72 mm2; P = 0.007) after the completion of treatment (T2 - T1) for the Hyrax group was suggested. No statistically significant difference was found in the Damon group for volume (1 mL; P = 0.311) and for MCA (7.32 mm2; P = 0.643). In addition, no statistically significant difference was found in the breathing function in both treatment groups (P >0.05). CONCLUSIONS: Hyrax expansion followed by fixed appliances produced more dimensional upper airway changes at the oropharyngeal level than the Damon system approach. No breathing functional changes were noted in either samples.


Assuntos
Maxila , Técnica de Expansão Palatina , Adolescente , Criança , Tomografia Computadorizada de Feixe Cônico , Humanos , Nariz , Orofaringe/diagnóstico por imagem
4.
J Clin Sleep Med ; 2021 Mar 22.
Artigo em Inglês | MEDLINE | ID: mdl-33745506

RESUMO

STUDY OBJECTIVES: To analyze differences in mandibular cortical width (MCW) among children diagnosed with Obstructive sleep apnea (OSA) or at high- or low-risk for OSA. METHODS: 161 children were assessed: 60 children with polysomnographically (nPSG) diagnosed OSA, 56 children presenting symptoms suggestive of high-risk for OSA, and 45 children at low-risk for OSA. Children at high- and low-risk for OSA were evaluated through the Pediatric Sleep Questionnaire (PSQ). MCW was calculated from panoramic radiograph images available from all subjects using ImageJ software. Differences between MCW measurements in the three groups were evaluated using ANCOVA and Bonferroni post-hoc tests, with age as a covariate. The association between MCW and specific cephalometric variables was assessed through regression analysis. RESULTS: The participants' mean age was 9.6±3.1 years (59% male and 41% female). The mean BMI z-score was 0.62±1.3. The nPSG-OSA group presented smaller MCW than at low-risk for OSA group (mean difference= -0.385 mm, p=0.001), but no difference with the at high-risk for OSA group (nPSG-OSA vs. high-risk OSA: p=0.085). In addition, the MCW in the at high-risk for the OSA group was significantly smaller than the at low-risk for the OSA group (mean difference= -0.301 mm, p=0.014). The cephalometric variables (SNA and FMA) explained only 8% of the variance in MCW. CONCLUSIONS: Reductions in MCW appear to be present among children with OSA or those at high risk for OSA, suggesting potential interactions between mandibular bone development and/or homeostasis and pediatric OSA.

5.
Orthod Craniofac Res ; 2021 Feb 10.
Artigo em Inglês | MEDLINE | ID: mdl-33567160

RESUMO

BACKGROUND: The current systematic review aimed to assess the impact of intraoral non-surgical non-pharmacological adjunctive interventions on orthodontically induced inflammatory root resorption (OIIRR). SEARCH METHODS: Search without restrictions was performed up to November 2020 in three electronic databases (Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE) for randomized controlled trials (RCTs), prospective and retrospective non-randomized studies. The ROB 2.0 tool was used to assess the quality of the included RCTs, and the ROBINS-I tool was applied to non-randomized clinical studies. The strength of evidence was ranked using GRADE. RESULTS: Three hundred and sixteen records were initially retrieved. A total of 10 studies, with 236 patients, were finally considered. These studies assessed the effects of mechanical vibration (low-frequency and high-frequency), low-intensity pulsed ultrasound (LIPUS), low-level laser therapy (LLLT) and photobiomodulation (light-emitting devices (LED). While the low-frequency vibration and LED do not seem to affect OIIRR, OIIRR has been reported to be reduced in high-frequency vibration, and LIPUS-treated teeth (differences may not likely be considered clinically relevant). The potential positive effect of LLLT on OIIRR is still debatable. Overall, the existing evidence suggests that the amount of OIIRR observed while using these interventions with traditional orthodontic treatment was not more than that was observed without it. CONCLUSIONS: Based on a very low level of confidence, it seems that intraoral non-pharmacological non-surgical adjunctive interventions do not affect the amount of OIIRR either positively or negatively to a clinically relevant degree when compared to what is seen with conventional orthodontic treatment alone.

6.
Am J Orthod Dentofacial Orthop ; 159(3): e253-e273, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33541785

RESUMO

INTRODUCTION: The purpose of this research was to compare mandibular growth rotation relative to the cranial base in different vertical facial patterns on the basis of multiple 2-dimensional (2D) and 3-dimensional (3D) superimposition methods. METHODS: Cone-beam computed tomography (CBCT) images taken at a mean interval of 54.8 ± 16.8 months were assessed from a sample of 70 growing patients. Three mandibular superimposition methods were compared against Björk's structural method: (1) a 2D landmark method (2D-M1), (2) a voxel-based 3D method based on a previously reported method (3D-M1), and (3) a voxel-based 3D method incorporating symphyseal structures as references (3D-M2). After superimposition, the relative change in cranial base lines as depicted in sagittal views were measured for true mandibular rotation. Agreement between methods was assessed with Lin's concordance correlation coefficient, Bland-Altman's limits of agreement, and the Bradley-Blackwood test. RESULTS: Lin's concordance correlation coefficients ranged between 0.924 for the 2D-M1 method, 0.695 for the 3D-M1 method, and 0.965 for the 3D-M2 method. Bland-Altman limits of agreement were wide for all but the 3D-M2 method. Finally, the Bradley-Blackwood test of equality of means and variances was significant in all except the 3D-M2 method. CONCLUSIONS: For time intervals between CBCT volume acquisitions >3 years, the use of the 2D-M1 and 3D-M1 methods is not recommended. There was a high concordance between the 3D-M2 method and Björk's structural method when assessing mandibular growth rotation using relative changes in cranial base lines. The high concordance was displayed across all vertical facial types and for all time differences between first and second CBCT data acquisitions.


Assuntos
Imageamento Tridimensional , Mandíbula , Tomografia Computadorizada de Feixe Cônico , Humanos , Mandíbula/diagnóstico por imagem , Reprodutibilidade dos Testes , Base do Crânio/diagnóstico por imagem
7.
Am J Orthod Dentofacial Orthop ; 159(4): e321-e329, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33568275

RESUMO

INTRODUCTION: Although there is relative consensus about approaches to gingival smile management, there are still discrepancies as to whether a gingival smile is attractive or not. The purpose of this study was to quantify the influence of upper lip curvature shape and the amount of gingival display on the perception of smile attractiveness assessed by Peruvian orthodontists, dentists, and laypersons. METHODS: A frontal photograph was digitally altered to generate 3 types of upper lip curvature shapes (upward, straight, and downward) with 5 different levels of gingival smile exposure (0 mm, 2 mm, 3 mm, 4 mm, and 5 mm). Fifteen images were generated. Three groups of evaluators (50 dentists, 50 orthodontists, and 50 laypersons) assessed the images using a visual analog scale. One-way analysis of variance with Bonferroni post-hoc tests and multiple linear regressions were applied. RESULTS: The downward lip curvature shape had a negative effect on the esthetic evaluation of the smile with gingival exposures of 3 mm or more for all the evaluating groups (approximately 20-30 points less than upward or straight smile curvature shapes, P <0.05). Laypeople gave higher scores of almost 10 points more than dentists and orthodontists when evaluating the upward lip curvature shape with 5 mm of gingival exposure during smile (P = 0.029). CONCLUSIONS: We found that upward or straight upper lip curvature shapes have a positive impact on perceived smile esthetics. In contrast, downward upper lip curvature shapes have a negative effect on perception when evaluating different degrees of gingival smiles.


Assuntos
Lábio , Saúde Bucal , Atitude do Pessoal de Saúde , Atitude Frente a Saúde , Estudos Transversais , Odontólogos , Estética Dentária , Humanos , Incisivo , Sorriso
8.
Dis Model Mech ; 2021 Jan 11.
Artigo em Inglês | MEDLINE | ID: mdl-33431521

RESUMO

Pediatric obstructive sleep apnea (OSA), a relatively common sleep-related breathing disorder (SRBD) affecting approximately 1-5% of children, is often caused by anatomical obstruction and/or collapse of the nasal and/or pharyngeal airways. The resulting sleep disruption and intermittent hypoxia lead to various systemic morbidities. Predicting the development of OSA from craniofacial features alone is currently not possible and a controversy remains if upper airway obstruction facilitates reduced midfacial growth or vice-versa. Currently, there is no rodent model that recapitulates both the development of craniofacial abnormalities and upper airway obstruction to address these questions. Here, we describe that mice with a neural crest-specific deletion of Bmp7 (Bmp7ncko) present with shorter, more acute angled cranial base, midfacial hypoplasia, nasal septum deviation, turbinate swelling and branching defects, and nasal airway obstruction. Interestingly, several of these craniofacial features develop after birth during periods of rapid midfacial growth and precede the development of an upper airway obstruction. We identified that in this rodent model, no single feature appeared to predict upper airway obstruction, but the sum of those features resulted in a reduced breathing frequency, apneas and overall reduced oxygen consumption. Metabolomics analysis of serum from peripheral blood identified increased levels of hydroxyproline, a metabolite upregulated under hypoxic conditions. As this model recapitulates many features observed in OSA, it offers unique opportunities for studying how upper airway obstruction affects breathing physiology and leads to systemic morbidities.

9.
Am J Orthod Dentofacial Orthop ; 159(2): e135-e147, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33388201

RESUMO

INTRODUCTION: The purposes of this study were to characterize the 3-dimensional position of teeth adjacent to impacted canines and examine whether impaction affects canine development using cone-beam computed tomography. METHODS: Cone-beam computed tomography images of 34 unilateral maxillary impacted canines (12 males, 22 females; mean age, 16.5 years) were collected. Twenty-one canines were palatally impacted (PIC), and 13 were buccally impacted (BIC). Angular measurements of lateral incisors (LIs), first premolars, and the impacted canines positions relative to a 3-dimensional coordinate system and canines' volume, length, and shape of the roots, were compared between the affected and contralateral control sides. The influence of canine position and severity of impaction was examined. Statistics included the paired t test, Wilcoxon signed rank test, and McNemar test. RESULTS: In the PIC group, LIs showed significant mesiobuccal rotation (-17.1°), mesial angulation (8.4°), and buccal root torque (5°) and first premolars mesiobuccal rotation (6.1°). In the BIC group, LIs displayed mesiobuccal rotation (-18°) and significant palatal root torque (-5°). The canine volumes were similar in BICs and slightly smaller in PICs. The lengths were shorter in both, but root hooks were more prevalent in BICs. The severity of impaction affected the measured variables. CONCLUSIONS: The differential position of the adjacent teeth is pathognomonic for PIC vs BIC, and impaction seems to affect canine development. The findings provide evidence-based clinical and radiographical clues for early diagnosis of canine displacement and planning the most efficient treatment strategy. In addition, they support timely orthodontic eruption before the development of the apical third of the root.


Assuntos
Dente Canino , Dente Impactado , Adolescente , Dente Pré-Molar , Tomografia Computadorizada de Feixe Cônico , Dente Canino/diagnóstico por imagem , Feminino , Humanos , Incisivo , Masculino , Maxila/diagnóstico por imagem , Dente Impactado/diagnóstico por imagem
10.
Pediatr Pulmonol ; 2021 Jan 26.
Artigo em Inglês | MEDLINE | ID: mdl-33501761

RESUMO

The significant contribution of dental professionals to the management of selected adult obstructive sleep apnea (OSA) cases is understood. Among children, it has also been suggested that dental professionals may also help screen and manage this morbidity in selected cases. It has also been noted that our understanding of pediatric OSA lags significantly behind adult OSA. During the screening process for potential pediatric OSA cases, dental professionals may be quite helpful as specific craniofacial abnormalities have been previously associated with pediatric OSA, including Class II malocclusion, vertical facial growth and maxillary transversal deficiency. As dental professionals assess children more frequently than physicians, they can help screen sleep-disordered breathing signs and symptoms using validated questionnaires. In more advanced cases, orthodontists may be leading contributors to the management of selected cases where a craniofacial involvement is suspected. Rapid maxillary expansion and mandibular or maxillary anterior repositioning devices have been proposed as managing alternatives. So far, there is no substantial evidence if these approaches can be adopted to treat OSA fully or if the reported OSA signs and symptoms improvements observed in a selected group of patients are stable long-term. Nevertheless, dentists and orthodontists' integration into a transdisciplinary team should be encouraged to play a significant role. This review discusses dentists or orthodontists' potential contribution to screen and manage selective pediatric OSA patients as part of a transdisciplinary team.

11.
J Evid Based Dent Pract ; 20(4): 101490, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33303099

RESUMO

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Optimal force magnitude for bodily orthodontic tooth movement with fixed appliances: A systematic review. Theodorou CI, Kuijpers-Jagtman AM, Bronkhorst EM, Wagener FADTG. Am J Orthod Dentofacial Orthop. 2019;156(5):582-592. SOURCE OF FUNDING: No funding involved. TYPE OF STUDY/DESIGN: Systematic review.

12.
Angle Orthod ; 90(4): 571-577, 2020 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-33378491

RESUMO

OBJECTIVE: To evaluate the esthetic perceptions of orthodontists and laypersons for facial profile changes after orthodontic treatment using Herbst or Forsus appliances. MATERIALS AND METHODS: Pre- and posttreatment facial profile contour images of 20 Class II patients treated with Herbst (group H; n = 10) and Forsus (group F; n = 10) appliances were analyzed by 30 orthodontists and 30 laypersons, who graded them from 1 (unattractive) to 10 (very attractive) using a visual analog scale. Two assessments were carried out with a 15 day-interval. In the first evaluation, 40 images were presented in a random sequence. In the second evaluation, initial and final facial profile images of each patient were randomly presented side by side. To compare groups in relation to treatment method, Mann-Whitney tests were used. To evaluate differences between time points, Wilcoxon tests were used. RESULTS: In the first evaluation, there was a significant difference between initial and final images only for group H, for both laypersons (P = .017) and orthodontists (P = .037). There was also a significant difference between laypersons and orthodontists in their ratings of posttreatment Herbst appliance profiles (P = .028). There was no significant difference between initial and final facial profile images for group F and no significant differences between or within evaluator groups in their ratings of initial or final Forsus appliance profiles. In the second evaluation, there was a significant difference between appliance groups only for laypersons, who considered cases treated with the Herbst appliance more attractive than those treated with the Forsus (P = .031). Laypersons also considered Herbst profiles more attractive than did orthodontists (P = .047). CONCLUSIONS: Class II malocclusion treatment using the Herbst appliance may produce a more esthetically improved facial profile silhouette compared with Forsus appliances. The magnitude of perceived changes may not be considered clinically relevant.


Assuntos
Má Oclusão de Angle Classe II , Aparelhos Ortodônticos Funcionais , Cefalometria , Estética , Humanos , Má Oclusão de Angle Classe II/diagnóstico por imagem , Má Oclusão de Angle Classe II/terapia , Percepção , Resultado do Tratamento
13.
J Oral Rehabil ; 2020 Dec 30.
Artigo em Inglês | MEDLINE | ID: mdl-33377534

RESUMO

To synthesise and critically review the association between sleep bruxism (SB) and stress symptoms in adults. A systematic review was performed. The search was completed using seven primary electronic databases in addition to a grey literature search. Two reviewers blindly selected studies based on pre-defined eligibility criteria. Risk of bias of the included articles was performed using the Joanna Briggs Institute Critical Appraisal Checklist for Analytical Cross-Sectional Studies. RevMan 5.4 was used to perform the meta-analysis. The quality of evidence was evaluated according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Ten studies were included for qualitative analysis, of which three were included for quantitative analysis. Three studies were evaluated to have low risk of bias, and seven were assessed with moderate risk of bias. Quality of evidence was classified as very low for all outcomes. Individuals with SB were found to have higher levels of some self-reported stress symptoms as assessed through questionnaires with a mean difference of 4.59 (95% CI 0.26-8.92). Biomarkers like epinephrine, norepinephrine, cortisol, adrenaline, dopamine, noradrenaline and prolidase enzyme levels also showed a positive association with SB. Although some associations were identified between probable SB and self-reported stress symptoms and biomarkers of stress in adults, given that the quality of evidence was found to be very low, caution should be exercised in interpreting these results. These findings suggest that additional and better designed studies are warranted in order to clarify the link between SB and stress.

14.
Clin Oral Investig ; 2020 Nov 17.
Artigo em Inglês | MEDLINE | ID: mdl-33200283

RESUMO

OBJECTIVE: To critically appraise available literature concerning the effect of cyanoacrylate tissue adhesive (CTA) in postoperative palatal pain management. MATERIALS AND METHODS: Electronic databases (Cochrane, PubMed, LILACS, Scopus, and Web of Science) were searched, complemented with grey literature databases up to June 2020. Studies reporting the effect of cyanoacrylate tissue adhesive compared to any other methods in postoperative palatal pain management were considered eligible. The risk of bias among and across included studies was assessed. RESULTS: Finally, four studies were considered eligible. Regarding free gingival graft (FGG), cyanoacrylate tissue adhesive with hemostatic sponge promoted less postoperative pain (PP) and analgesic consumption (AC). Also, cyanoacrylate tissue adhesive with platelet-rich fibrin produced less PP and more wound healing at the palatal area than cyanoacrylate tissue adhesive and wet gauze. Additionally, cyanoacrylate tissue adhesive promoted less PP and AC than wet gauze and suture. Concerning connective tissue graft (CTG), cyanoacrylate tissue adhesive, and suture produced similar PP, AC, and willingness for retreatment. CONCLUSIONS: Based on the low certainty level, cyanoacrylate tissue adhesive appears to promote less PP and AC than wet gauze and suture regarding FGG. Additionally, cyanoacrylate tissue adhesive appears to increase the effect of hemostatic sponge, contributing to the reduction of PP and AC. Regarding CTG, cyanoacrylate tissue adhesive appears to promote similar PP, AC, and willingness for retreatment than the suture. Therefore, cyanoacrylate tissue adhesive has shown promising usefulness for PP management in FGG, but not a clear benefit for CTG. CLINICAL RELEVANCE: The adoption of different agents for the protection of the palatal donor site following gingival harvesting procedures may provide better comfort to the patient.

15.
Braz Oral Res ; 34: e123, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33146319

RESUMO

During the COVID-19 pandemic the use of cloth masks has increased dramatically due to the shortage of medical masks. However, the efficiency of this material is controversial. We aimed to investigate the efficiency of cloth masks in reducing transmission and contamination by droplets and aerosols for the general population and healthcare workers. Electronic databases were searched without year or language restrictions. Clinical and laboratorial studies were included. The risk of bias (RoB) was assessed using an adapted quality checklist for laboratory-based studies. ROBINS-I tool and Cochrane RoB 2.0 were used to evaluate non-randomized (n-RCT) and randomized clinical trials (RCT), respectively. The quality of the evidence was assessed through GRADE tool. From the eleven studies selected, eight were laboratory-based studies, one non-randomized and one RCT supported by laboratory data. Between the evaluated fabrics only three presented a filtration efficiency > 90%. Hybrid of cotton/chiffon (95%CI 95.2 to 98.8), hybrid of cotton/silk (95%CI 92.2 to 95.8) and cotton quilt (95%CI 94.2 to 97.8). However, cloth masks are not recommended for healthcare workers. A meta-analysis was not feasible due to a high methodological heterogeneity. The overall quality of evidence ranged from very low to moderate. Despite the lower efficiency compared to medical masks, laboratorial results may underestimate the efficiency of cloth masks in real life. Cloth mask efficiency is higher when made of hybrid fabrics (cotton/chiffon, cotton/silk) and cotton quilt, mainly with multiple layers.


Assuntos
Betacoronavirus , Infecções por Coronavirus , Máscaras , Pandemias , Pneumonia Viral , Humanos
16.
J Pers Med ; 10(4)2020 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-33066413

RESUMO

Personalized dental medicine requires from precise and customized genomic diagnostic. To conduct an association analysis over multiple putative loci and genes located at chromosomes 2, 4, 8, 12, 18, X, and Y, potentially implicated in an extreme type of external apical root resorption secondary to orthodontic forces (aEARR). A genome-wide association study of aEARR was conducted with 480 patients [ratio~1:3 case/control]. Genomic DNA was extracted and analyzed using the high-throughput Axiom platform with the GeneTitan® MC Instrument. Up to 14,377 single nucleotide polymorphisms (SNPs) were selected at candidate regions and clinical/diagnostic data were recorded. A descriptive analysis of the data along with a backward conditional binary logistic regression was used to calculate odds ratios, with 95% confidence intervals [p < 0.05]. To select the best SNP candidates, a logistic regression model was fitted assuming a log-additive genetic model using R software [p < 0.0001]. In this sample the top lead genetic variants associated with aEARR were two novel putative genes located in the X chromosome, specifically, STAG 2 gene, rs151184635 and RP1-30E17.2 gene, rs55839915. These variants were found to be associated with an increased risk of aEARR, particularly restricted to men [OR: 6.09; 95%CI: 2.6-14.23 and OR: 6.86; 95%CI: 2.65-17.81, respectively]. Marginal associations were found at previously studied variants such as SSP1: rs11730582 [OR: 0.54; 95%CI: 0.34-0.86; p = 0.008], P2RX7: rs1718119 [OR: 0.6; 95%CI: 0.36-1.01; p = 0.047], and TNFRSF11A: rs8086340 [OR: 0.6; 95%CI: 0.38-0.95; p = 0.024]), found solely in females. Multiple putative genetic variants located at chromosomes X and Y are potentially implicated in an extreme phenotype of aEARR. A gender-linked association was noted.

17.
Int Orthod ; 2020 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-33071153

RESUMO

INTRODUCTION: It has been suggested that heat-activated NiTi archwires (HANT) speed up crowding alleviation. HANT wires are available with different austenite finish temperatures. OBJECTIVE: The aim of the present study was to compare the effectiveness of two alignment sequences using thermally activated archwires with different austenite activation temperatures for the correction of mandibular anterior crowding. MATERIAL AND METHODS: The following NiTi archwire sequence was used for both groups: 0.012 in (conventional NiTi), 0.018 in (heat-activated NiTi archwires), 0.016×0.022 in (heat-activated NiTi archwires) and 0.019×0.025 in (conventional NiTi). The conventional NiTi used for both groups belongs to the same commercial brand. Two different austenite activation temperatures (35°C and 37°C) were used for the heat-activated archwires. The primary outcome was the degree of crowding correction measured on study models. The secondary outcome was crowding survival time over a six-month period. This RTC included fifty-four patients that were randomly allocated to the two different archwire sequences. A Mann-Whitney test was used to compare the groups regarding crowding alleviation. A survival curve was created using the Kaplan-Meier method to illustrate the reduction of crowding over time. A Mantel-Cox log-rank test was used to compare survival times (until correction of crowding). RESULTS: No differences in crowding alleviation were identified between both groups (log-rank test; P=0.77). CONCLUSIONS: The two alignment sequences with different thermal activated archwires at 35°C and 37°C achieved similar clinical results during the correction of mandibular anterior crowding.

18.
J Evid Based Dent Pract ; 20(3): 101423, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32921377

RESUMO

OBJECTIVE: To compare removable and fixed orthodontic devices in the correction of non-skeletal anterior crossbite in children and adolescents in the mixed dentition. MATERIALS AND METHODS: Electronic searches were conducted in the following databases: PubMed, Web of Science, Scopus, Medline Ovid, Lilacs, US Clinical Trials, and Proquest. A hand search of the reference lists of the included articles and a Google Scholar search were also conducted. References were evaluated by 2 review authors. Articles that met the eligibility criteria were included. Data extraction, methodological quality assessment (Cochrane tool), and strength of the evidence evaluation (GRADE) were also carried out. RESULTS: Seven articles were included. The results showed that removable and fixed devices were equally efficacious for overjet correction. Removable and fixed devices can also present inconveniences regarding pain and discomfort levels, the accomplishment of everyday activities (leisure and school), and the performance of functions, such as chewing and speech. However, treatment time and costs were significantly lower in orthodontic therapy with fixed appliances. Sequence generation, allocation concealment, and complete outcome data were not a concern. Blinding of participants or personnel was not reported in any article, and blinding of the assessor was a concern in 2 articles. Selective reporting was a concern in 2 articles. The certainty of the evidence for overjet correction was very low. CONCLUSION: Removable and fixed orthodontic devices are efficacious for overjet correction in non-skeletal anterior crossbite. However, treatment time and costs are lower for cases treated with fixed devices.


Assuntos
Má Oclusão , Sobremordida , Adolescente , Criança , Dentição Mista , Humanos , Má Oclusão/terapia
19.
Prog Orthod ; 21(1): 35, 2020 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-32888097

RESUMO

OBJECTIVES: The aim of this systematic review and meta-analysis is to assess the degree of stability of anterior open bite (AOB) treatment performed through the molar intrusion supported with skeletal anchorage at least 1 year posttreatment. METHODS: This study was registered in PROSPERO (CRD42016037513). A literature search was conducted to identify randomized (RCT) or non-randomized clinical trials based including those considering before and after design. Data sources were electronic databases including PubMed, Cochrane Library, Science Direct, Google Scholar, Scopus, Lilacs, OpenGrey, Web of Science, and ClinicalTrials.gov . The quality of evidence was assessed through the JBI tool and certainty of evidence was evaluated through the GRADE tool. Random effects meta-analysis was conducted when appropriate. RESULTS: Six hundred twenty-four articles met the initial inclusion criteria. From these, only 6 remained. The mean posttreatment follow-up time was 2.5 years (SD = 1.04). The overbite showed a standardized mean relapse of - 1.23 mm (95% CI - 1.64, - 0.81, p < 0.0001). Maxillary and mandibular incisors presented a non-significant mean relapse, U1-PP - 0.04 mm (95% CI - 0.55, 0.48) and L1-MP - 0.10 mm (95% CI - 0.57, 0.37). Molar intrusion showed a relapse rate around 12% for the maxillary molars and a 27.2% for mandibular molars. CONCLUSION: The stability of AOB through molar intrusion using TADs can be considered relatively similar to that reported to surgical approaches, since 10 to 30% of relapse occurs both in maxillary and mandibular molars. The level of certainty ranged between very low and low. RCTs reporting dropout during the follow-up are in dire need.


Assuntos
Mordida Aberta , Procedimentos de Ancoragem Ortodôntica , Cefalometria , Humanos , Maxila , Dente Molar , Técnicas de Movimentação Dentária
20.
Prog Orthod ; 21(1): 29, 2020 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-32864724

RESUMO

BACKGROUND: The aim of this systematic review was to identify, evaluate, and provide a current literature about the influence of heritability on the determination of occlusal traits. MATERIALS AND METHODS: MEDLINE, SCOPUS, Web of Science, LILACS, and Google Scholar were searched without restrictions up to March 2020. Studies with twin method were considered and the risk of bias assessment was performed using quality of genetic association studies checklist (Q-Genie). The coefficient of heritability (h2), model-fitting approaches, and coefficient correlation were used to estimate the genetic/environmental influence on occlusal traits. The GRADE tool was used to assess the quality of the evidence. RESULTS: Ten studies met the eligibility criteria. Three studies presented good quality, five moderate quality, and two poor quality. Most studies have found that the intra-arch traits, mainly the maxillary arch morphology, such as width (h2 16-100%), length (h2 42-100%), and shape (h2 42-90%), and the crowding, mainly for mandibular arch (h2 35-81%), are under potential heritability influence. The traits concerning the inter-arch relationship, as overjet, overbite, posterior crossbite, and sagittal molar relation, seem not to be genetically determined. The certainty of the evidence was graded as low for all outcomes. CONCLUSIONS: Although weak, the available evidence show that the heritability factors are determinant for the intra-arch traits, namely, arch morphology and crowding. Possibly due they are functionally related, the occlusal traits concerning the maxillary and mandibular relationship seem to have environmental factors as determinants. In this scenario, early preventive approaches can offer a more effective and efficient orthodontic treatment.


Assuntos
Má Oclusão de Angle Classe II , Má Oclusão , Sobremordida , Humanos , Mandíbula , Maxila
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