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Kardiologiia ; 60(12): 48-63, 2021 Jan 19.
Artigo em Russo | MEDLINE | ID: mdl-33522468


Diagnosis of heart failure with preserved ejection fraction (HFpEF) is associated with certain difficulties since many patients with HFpEF have a slight left ventricular diastolic dysfunction and normal filling pressure at rest. Diagnosis of HFpEF is improved by using diastolic transthoracic stress-echocardiography with dosed exercise (or diastolic stress test), which allows detection of increased filling pressure during the exercise. The present expert consensus explains the requirement for using the diastolic stress test in diagnosing HFpEF from clinical and pathophysiological standpoints; defines indications for the test with a description of its methodological aspects; and addresses issues of using the test in special patient groups.

Pesquisa Biomédica , Cardiologia , Insuficiência Cardíaca , Consenso , Ecocardiografia , Ecocardiografia sob Estresse , Teste de Esforço , Insuficiência Cardíaca/diagnóstico por imagem , Humanos , Federação Russa , Volume Sistólico , Função Ventricular Esquerda , Carga de Trabalho
Kardiologiia ; 57(S1): 312-322, 2017.
Artigo em Russo | MEDLINE | ID: mdl-29276904


The article discusses the issue of searching for optimum oral anticoagulants to prevent thrombosis and embolism induced by heart disease both in patients with atrial fibrillation and sinus rhythm. A complex bidirectional relationship between atrial fibrillation and coronary atherosclerosis is considered along with possible mechanisms for development of myocardial infarction in patients with atrial fibrillation. The authors provided evidence-based data which can be used in selecting an anticoagulant for prevention of heart disease induced thrombosis and embolism taking into account both the efficacy and safety established in randomized clinical studies.

Anticoagulantes/uso terapêutico , Fibrilação Atrial/complicações , Embolia/prevenção & controle , Isquemia Miocárdica/complicações , Anticoagulantes/administração & dosagem , Fibrilação Atrial/fisiopatologia , Doença da Artéria Coronariana/complicações , Doença da Artéria Coronariana/fisiopatologia , Embolia/etiologia , Humanos , Infarto do Miocárdio/etiologia , Isquemia Miocárdica/fisiopatologia
Kardiologiia ; 57(2): 62-67, 2017 Feb.
Artigo em Russo | MEDLINE | ID: mdl-28290793


Modern strategy of antihypertensive therapy base on the results of recently published randomized clinical trials discusses in this article. Data about optimal components of triple combined antihypertensive pill and a history of design and implementation of combined antihypertensive drugs are reviewed. Role of combined antihypertensive pills in reduction of nonadherence antihypertensive therapy also discussed.

Anti-Hipertensivos/uso terapêutico , Quimioterapia Combinada , Hipertensão/tratamento farmacológico , Anlodipino/uso terapêutico , Humanos , Hipertensão/fisiopatologia , Indapamida/uso terapêutico , Perindopril/uso terapêutico