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Plant Foods Hum Nutr ; 67(1): 57-63, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22318745


Porophyllum tagetoides is an annual warm-weather herb that has an intense typical smell. Its leaves are commonly used in soup preparation and traditional medicine for treatment of inflammatory diseases. Its volatile compounds and antioxidant properties were evaluated in crude, aqueous and ethanol leaf extract and an oil emulsion using different antioxidant assays in vitro, such as: DPPH radical scavenging activity, redox potential, polyphenol content, reducing power and optical density. A high antioxidative activity was found when comparing leaves with stems. The crude extract from leaves showed a very high reducing power (2.88 ± 0.20 O.D.) and DPPH radical-scavenging activity (54.63 ± 4.80%), in concordance with a major concentration of vitamin C (23.97 ± 0.36 mg/100 g). Instead, the highest polyphenol content (264.54 ± 2.17 mg GAE/g of sample) and redox potential (561.23 ± 0.15 mV) were found by the ethanol and aqueous extract, respectively. Aldehydes and terpenes such as nonanal, decanal, trans-pineno, ß-myrcene and D-limonene were the major volatiles found. This study suggests that Porophyllum tagetoides extracts could be used as antioxidants.

Antioxidantes/análise , Asteraceae/química , Sequestradores de Radicais Livres/análise , Óleos Voláteis/análise , Extratos Vegetais/química , Polifenóis/análise , México , Oxirredução , Folhas de Planta/química , Caules de Planta/química
QJM ; 94(7): 357-63, 2001 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-11435631


Diagnosis and treatment of Strongyloides stercoralis infection can be difficult, and a high degree of clinical suspicion in patients who have visited an endemic area is required. We describe the epidemiology and clinical features of 152 prospectively identified cases of strongyloidiasis in an European region, and identify risk factors for the development of severe forms of the disease. This was a prospective study of all patients admitted to a single institution over an 8-year period. Patients (n=152) were mainly elderly male farmers (79%) who had acquired the disease by working barefoot in contact with soil and ingesting non-drinking water. Eosinophilia was a sensitive marker for the infection (82%). Twenty patients (13%) developed severe forms of the illness and six patients (4%) died. A significant association was found between severe forms of strongyloidiasis and steroid usage (OR 9.0, 95%CI 2.1-37.6), immunodebilitating illness (OR 10.1, 95%CI 3.2-32.3) and other immunosuppressive therapy (OR 13.7, 95%CI 2.9-58.7), but by logistic regression analysis, only immunodebilitating disease was as a risk factor (OR 2.1, 95%CI 1.78-2.43). S. stercolaris infection is endemic in the Spanish Mediterranean coast. The frequent development of severe forms of the disease, with a high mortality, makes early recognition and treatment essential.

Doenças dos Trabalhadores Agrícolas/epidemiologia , Doenças Endêmicas , Strongyloides stercoralis , Estrongiloidíase/epidemiologia , Idoso , Doenças dos Trabalhadores Agrícolas/etiologia , Animais , Eosinofilia/etiologia , Feminino , Humanos , Hospedeiro Imunocomprometido/imunologia , Modelos Logísticos , Masculino , Estudos Prospectivos , Fatores de Risco , Fatores Sexuais , Sapatos , Espanha/epidemiologia , Cônjuges , Estrongiloidíase/etiologia , Água/parasitologia