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1.
Urology ; 117: 131-136, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29649545

RESUMO

OBJECTIVE: To demonstrate the long-term outcome of a contemporary series of 64 children who underwent complete primary repair of bladder exstrophy (CPRE) in a single tertiary referral center. MATERIALS AND METHODS: Between 1998 and 2012, 64 children, 47 boys and 17 girls, were identified. Only 60 of the 64 cases were available for follow-up. The follow-up was done by renal bladder ultrasound and serum creatinine every 3 months and voiding cystourethrogram from 6 to 12 months postoperatively. Continence was defined as dryness ≥3 hours. RESULTS: Median (range) follow-up is 14 years (from 5 to 19 years). Voided continence was achieved in 14 children (23%) after CPRE only. Additionally, 6 children were continent after bladder neck reconstruction (BNR) and 2 after bladder neck injection (BNI), raising the percentage of voided continence to 36%. The remaining 38 (64%) patients were using clean intermittent catheterization. All cases were continent at last assessment. The results of BNR or BNI were better in de novo than in redo cases (P <.05). The percentage of cases that needed augmentation ileocystoplasty in combination with multiple bladder neck procedures was lower in both female and de novo cases (P <.05). CONCLUSION: The percentage of children with classic bladder exstrophy who underwent CPRE who will achieve continence with volitional voiding via the urethra is 36%. The continence results after BNR and BNI are better in de novo cases than in redo ones. Continence in female and de novo cases is more likely to be achieved with lower number of continence procedures.

2.
J Pediatr Surg ; 53(8): 1461-1463, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29680277

RESUMO

OBJECTIVE: To detect whether grafting the incised plate during Snodgrass repair would improve outcome. MATERIALS AND METHODS: Sixty patients with primary distal hypospadias were included. Patients were equally randomized using closed envelop method to either Snodgrass or grafted tubularized incised plate repair (GTIP). All operations were performed by a single surgeon. All intaroperative data were recorded. All patients were followed up for 1 year. Success was defined as slit shaped meatus at the tip of the glans with no stenosis, fistula or diverticulum. RESULTS: All 60 patients were evaluated at 1 year of follow-up. Mean age at surgery was 40±15months. Both groups were comparable as regard to patients' age, meatus location, length and width and depth of urethral plate and glans width. Success was documented in 29/30 patients (96.7%) in the Snodgrass group. The only complication was meatal stenosis in one patient, whereas success was documented in 28/30 patients (93.3%) in the GTIP group. The two failures were secondary to partial glans dehiscence. Success rate was not statistically different. Flow rate data at 1 year showed insignificant difference between both groups as regards Q-max and voiding time. The only statistically significant difference between both groups was a longer operative time 106±12min in the GTIP group compared to only 77±9 for the Snodgrass group (p = 0.005). CONCLUSIONS: Snodgrass and GTIP techniques for primary distal hypospadias repair have similar outcome. With a significantly shorter operative time, Snodgrass repair remains the first choice for primary distal hypospadias repair. TYPE OF THE STUDY: Prospective randomized study. LEVEL OF EVIDENCE: Level I.


Assuntos
Hipospadia/cirurgia , Procedimentos Cirúrgicos Reconstrutivos/métodos , Retalhos Cirúrgicos , Uretra/cirurgia , Procedimentos Cirúrgicos Urológicos Masculinos/métodos , Pré-Escolar , Fístula/cirurgia , Seguimentos , Humanos , Lactente , Masculino , Estudos Prospectivos , Resultado do Tratamento
3.
Urology ; 108: 171-174, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28705578

RESUMO

Cloacal duplication is an exceedingly rare group of anomalies with a limited number of cases reported so far. The anomaly may be confined to partial bladder duplication or it may involve complete duplication of the urogenital tract, hindgut, spine, lower limbs, and vascular structures. Every case is unique and ought to be approached individually. By means of imaging studies and endoscopy, anatomic details should be carefully defined before endorsing surgical correction. A satisfactory outcome can be achieved in the majority of cases. In this report, we describe 3 girls with cloacal duplication, and review pertinent imaging and surgical management.


Assuntos
Cloaca/anormalidades , Gerenciamento Clínico , Procedimentos Cirúrgicos Reconstrutivos/métodos , Anormalidades Urogenitais/cirurgia , Procedimentos Cirúrgicos Urogenitais/métodos , Criança , Pré-Escolar , Cloaca/diagnóstico por imagem , Cloaca/cirurgia , Cistoscopia , Feminino , Humanos , Lactente , Imagem por Ressonância Magnética , Doenças Raras , Ultrassonografia , Anormalidades Urogenitais/diagnóstico
4.
Urology ; 101: 161-162, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27993712

RESUMO

Bladder neck closure (BNC) is the ultimate bladder neck reconstruction. If reconstruction fails, closure must be considered as it gives the highest continence rate. The vast majority of BNCs are performed through an abdominal approach (either transvesical or extravesical approach), but perineal approach remains an option for BNC with considerable success rate. Perineal hernia, which is defined as protrusion of abdominal contents through the perineal defect, is a very rare complication after urologic procedures. We report a case of perineal hernia post perineal BNC.


Assuntos
Epispadia/cirurgia , Hérnia/etiologia , Herniorrafia/métodos , Períneo , Complicações Pós-Operatórias/etiologia , Telas Cirúrgicas , Procedimentos Cirúrgicos Urológicos Masculinos/efeitos adversos , Criança , Hérnia/diagnóstico , Humanos , Masculino , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/cirurgia , Reoperação , Tomografia Computadorizada por Raios X , Bexiga Urinária/diagnóstico por imagem , Bexiga Urinária/cirurgia , Urografia
6.
J Urol ; 194(5): 1414-9, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25986509

RESUMO

PURPOSE: We sought to evaluate long-term outcomes of the Bricker conduit urinary diversion in children. MATERIALS AND METHODS: We retrospectively reviewed the database of a single tertiary center for children who had undergone ileal conduit between 1981 and 2011. Patients followed for less than 1 year were excluded. Patient files were reviewed for demographics, diversion indication, preoperative imaging, surgical details, hospital readmissions and followup data. Renal function at baseline and last followup was assessed by estimated glomerular filtration rate, calculated using the modified Schwartz or MDRD (Modified Diet in Renal Disease) formula. Growth charts elucidated patient growth patterns, while an internally designed quality of life questionnaire demonstrated patient and family satisfaction with the procedure. RESULTS: We evaluated 29 children who underwent Bricker conduit at a median age of 10 years (range 2 to 18) and were followed for a median of 91 months (16 to 389). Neuropathic bladder was the underlying diagnosis in 72.4% of cases. Hydronephrosis improved or remained stable in 39 of 55 studied renal units (70.9%). Although no statistically significant difference was observed between mean ± SD baseline (64.5 ± 46 ml/minute/1.73 m(2)) and last followup estimated glomerular filtration rate (54.1 ± 44.9 ml/minute/1.73 m(2)), chronic kidney disease stage had worsened in 13 patients (44.8%), end-stage kidney disease had developed in 11 patients and 9 patients had died. Six patients underwent undiversion after stabilization of renal function. Linear growth was negatively affected in 12 patients (41.4%), and 85% reported poor quality of life. A total of 19 hospital readmissions were required in 14 patients to treat diversion related complications. CONCLUSIONS: The Bricker conduit does not seem to halt renal deterioration in children. Negative impact on growth and quality of life, and the anticipated rate of complications are significant limitations of the procedure in the pediatric population.


Assuntos
Íleo/cirurgia , Nefropatias/cirurgia , Complicações Pós-Operatórias/epidemiologia , Qualidade de Vida , Derivação Urinária/métodos , Adolescente , Criança , Pré-Escolar , Egito/epidemiologia , Feminino , Seguimentos , Humanos , Incidência , Masculino , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Derivação Urinária/psicologia
7.
Urology ; 85(1): 195-8, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25444630

RESUMO

OBJECTIVE: To report our experience with different approaches for management of pouch stones in children with ileal-based urinary reservoir. PATIENTS AND METHODS: Charts of children who underwent ileal-based urinary reservoirs between 2000 and 2009 were retrospectively reviewed. Patients who were diagnosed with reservoir calculi were identified; medical records were reviewed for patients' demographics, diversion details, stone criteria, mode of treatment, perioperative complications, and recurrence rate. RESULTS: We identified 26 children with pouch stones after urinary diversion. There were 11 boys (42%) and 15 girls (58%). Mean age was 11 years (range, 4-16 years). Mean time for diagnosis was 42 months (24-120 months). Pouch stones were asymptomatic in 10 patients (38%). Fifteen cases were postbladder augmentation and 11 cases postcontinent cutaneous diversion. The mean stone size was 4 cm (range, 1-10 cm), and mean Hounsfield Unit was 585 (205-1090). Seventeen children (65%) had positive urine culture result, whereas 9 children were sterile. Seven children (27%) required open poucholithotomy, whereas 19 patients (73%) were managed endoscopically. Percutaneous approach was done in 5 children, whereas urethral access was used in 7 children. Mechanical extraction was performed in 12 cases, and stone disintegration was required in 7 cases. Eight children developed stone recurrence. Mean time for recurrence was 11 months (range, 3-19 months). Six children were after endoscopic disintegration, and all required redo endoscopic extraction. Stone analysis was available in 15 patients (struvite stones in 10 cases and calcium phosphate in 5 cases). CONCLUSION: Pouch stones are established long-term complication of urinary diversion. Open and endoscopic approaches are valid treatment strategies.


Assuntos
Íleo/cirurgia , Complicações Pós-Operatórias/terapia , Bexiga Urinária/cirurgia , Cálculos Urinários/terapia , Coletores de Urina , Adolescente , Anastomose Cirúrgica , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Estudos Retrospectivos
8.
Urol Int ; 93(4): 406-10, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25139453

RESUMO

OBJECTIVE: To study the predictive value of 6 ultrasonographic (USG) parameters for early detection of children at risk of recurrent obstruction. PATIENTS AND METHODS: A prospective nonrandomized study included all patients who underwent pyeloplasty between 2010 and 2012. All of the patients had completed at least 6 months of follow-up and preoperative and postoperative USG imaging data were available. The primary outcome was the correlation between USG and diuretic scintigraphic parameters. The secondary outcome was the predictive ability of the pelvicalyceal system parameters, measured by USG, of parenchymal growth after surgery. RESULTS: Sixty-eight patients were evaluated. The mean age was 3.6 years (range 0.1-12). The mean (± standard deviation) differential renal function improved from 37.4 ± 11 ml/min to 37.7 ± 14 ml/min, which was a difference of no statistical significance. On the other hand, the mean (± SD) half-time (T1/2) significantly improved. After constructing a linear regression model of the 4 USG parameters and the parenchymal growth, the model explained 57.2% of the variance in parenchymal growth after pyeloplasty. The calyx-to-parenchyma ratio change was the largest unique contribution for explaining the variance in parenchymal growth, followed by anteroposterior diameter and calyceal dilatation. CONCLUSION: We proved that calyx-to-parenchyma ratio, anteroposterior diameter and calyceal dilatation are independent predictors of early success after pyeloplasty.


Assuntos
Rim/diagnóstico por imagem , Obstrução Ureteral/cirurgia , Procedimentos Cirúrgicos Urológicos/métodos , Fatores Etários , Criança , Pré-Escolar , Diurese , Feminino , Humanos , Lactente , Rim/crescimento & desenvolvimento , Masculino , Valor Preditivo dos Testes , Estudos Prospectivos , Radiografia , Recuperação de Função Fisiológica , Stents , Fatores de Tempo , Resultado do Tratamento , Ultrassonografia , Obstrução Ureteral/diagnóstico por imagem , Obstrução Ureteral/fisiopatologia , Procedimentos Cirúrgicos Urológicos/instrumentação
9.
Urol Int ; 93(4): 403-5, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24923679

RESUMO

AIM: To analyze the status of renal function after pyeloplasty in a large contemporary adult series and to detect which variables predict improvement of renal function. MATERIALS AND METHODS: 85 adult patients were retrospectively identified who had undergone pyeloplasty between January 2002 and May 2011 with available pre- and postoperative diuretic scintigraphy. Preoperative differential renal function (DRF) and single-kidney GFR (SKGFR) were obtained by (99m)Tc-MAG-3 diuretic scintigraphy. Baseline-weighted (bw-) DRF and SKGFR were calculated between baseline conditions and time of last follow-up. Factors that explain the variance of bw-DRF and bw-SKGFR were determined. RESULTS: The mean (SD) preoperative DRF significantly increased from 34% (11.6) to 37.2% (11.8) after pyeloplasty (p < 0.001). Similarly, mean (SD) SKGFR showed a significant improvement from 31.2 (12.9) to 35.9 (15) ml/min (p < 0.001). Patients with a lower baseline DRF (≤40%) showed a significant improvement as opposed to those with a higher baseline DRF (>40%) (p < 0.001 and 0.3, respectively). Baseline DRF and cortical thickness explained the variance in bw-DRF and bw-SKGFR with more contribution of baseline DRF. CONCLUSIONS: Renal function showed improvement after pyeloplasty in adults and preoperative DRF and cortical thickness were the predicting variables.


Assuntos
Rim/fisiopatologia , Obstrução Ureteral/cirurgia , Procedimentos Cirúrgicos Urológicos/métodos , Adolescente , Adulto , Idoso , Feminino , Taxa de Filtração Glomerular , Humanos , Rim/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Cintilografia , Compostos Radiofarmacêuticos , Recuperação de Função Fisiológica , Estudos Retrospectivos , Fatores de Risco , Stents , Tecnécio Tc 99m Mertiatida , Resultado do Tratamento , Obstrução Ureteral/complicações , Obstrução Ureteral/diagnóstico , Obstrução Ureteral/fisiopatologia , Procedimentos Cirúrgicos Urológicos/efeitos adversos , Procedimentos Cirúrgicos Urológicos/instrumentação , Adulto Jovem
10.
Urology ; 83(5): 1145-8, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24485997

RESUMO

OBJECTIVE: To evaluate the long-term outcomes of perineal anastomotic urethroplasty for post-traumatic pediatric posterior urethral strictures. METHODS: We retrospectively reviewed the medical records of 65 boys who had a perineal anastomotic urethroplasty for post-traumatic posterior urethral strictures between 1991 and 2010. Patients were followed up for a mean (range) of 78 (13-210) months by a history, urinary flow rate estimate, retrograde urethrography, and voiding cystourethrography. Regression analysis was done to assess the predictors of success after urethroplasty. RESULTS: The mean (range) age of the patients was 9.3 (3-16) years. The estimated radiographic stricture length before surgery was 2.4 (1-5) cm. All patients presented with a suprapubic cystostomy tube and scheduled for delayed or repeated correction of a urethral stricture. Twenty boys (30%) had failed previous attempts of repair elsewhere. Mean interval between the original trauma and repair in new cases, and since the last repair in recurrent cases, was 7 months. The perineal anastomotic repair was successful in 58 of 65 (89%) patients. All treatment failures were at the anastomosis and were within the first year. Failed repairs were successfully managed endoscopically in 5 patients and by repeat perineal anastomotic repair in the remaining 2. All boys are continent. There was no chordee or urethral diverticula during the follow-up. CONCLUSION: One-stage perineal anastomotic repair of post-traumatic urethral strictures in boys is feasible with minimal morbidity. Denovo cases and surgeon experience are the predictors of success after urethroplasty.


Assuntos
Períneo/cirurgia , Uretra/cirurgia , Estreitamento Uretral/cirurgia , Adolescente , Anastomose Cirúrgica/métodos , Criança , Pré-Escolar , Humanos , Masculino , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Procedimentos Cirúrgicos Urológicos/métodos
11.
J Urol ; 192(1): 194-9, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24518781

RESUMO

PURPOSE: Staging of childhood renal tumors is crucial for treatment planning and outcome prediction. We sought to identify whether computerized tomography could accurately predict the local stage of childhood renal tumors. MATERIALS AND METHODS: We retrospectively reviewed our database for patients diagnosed with childhood renal tumors and treated surgically between 1990 and 2013. Inability to retrieve preoperative computerized tomography, intraoperative tumor spillage and nonWilms childhood renal tumors were exclusion criteria. Local computerized tomography stage was assigned by a single experienced pediatric radiologist blinded to the pathological stage, using a consensus similar to the Children's Oncology Group Wilms tumor staging system. Tumors were stratified into up-front surgery and preoperative chemotherapy groups. The radiological stage of each tumor was compared to the pathological stage. RESULTS: A total of 189 tumors in 179 patients met inclusion criteria. Computerized tomography staging matched pathological staging in 68% of up-front surgery (70 of 103), 31.8% of pre-chemotherapy (21 of 66) and 48.8% of post-chemotherapy scans (42 of 86). Computerized tomography over staged 21.4%, 65.2% and 46.5% of tumors in the up-front surgery, pre-chemotherapy and post-chemotherapy scans, respectively, and under staged 10.7%, 3% and 4.7%. Computerized tomography staging was more accurate in tumors managed by up-front surgery (p <0.001) and those without extracapsular extension (p <0.001). CONCLUSIONS: The validity of computerized tomography staging of childhood renal tumors remains doubtful. This staging is more accurate for tumors treated with up-front surgery and those without extracapsular extension. Preoperative computerized tomography can help to exclude capsular breach. Treatment strategy should be based on surgical and pathological staging to avoid the hazards of inaccurate staging.


Assuntos
Neoplasias Renais/diagnóstico por imagem , Neoplasias Renais/patologia , Tomografia Computadorizada por Raios X , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Estadiamento de Neoplasias/métodos , Valor Preditivo dos Testes , Estudos Retrospectivos
12.
Can Urol Assoc J ; 8(11-12): E906-9, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25553164

RESUMO

INTRODUCTION: We compare percutaneous nephrolithotomy (PCNL) and open surgery in the treatment of staghorn stones in children. METHODS: We retrospectively reviewed the electronic records of children who underwent treatment for staghorn stones between September 2000 and August 2013. They were divided between Group 1 (patients who underwent PCNL) and Group 2 (patients who underwent open surgery). We compared stone-free and complications rates, need for multiple procedures, and hospital stay. RESULTS: The study included 41 patients (35 boys and 6 girls), with mean age 7.4 ± 3.1 years (range: 2-15). Of these 41 patients, 26 had unilateral renal stone and 15 had bilateral renal stones. The total number of treated renal units was 56: 28 underwent PCNL and 28 underwent open surgery. The complication rate was comparable for both groups (32% for open surgery vs. 28.6%, p = 0.771). Multiple procedures were more needed in PCNL group (60.7% vs. 32% in open surgery, p = 0.032). The stone-free rate was 71.4% after PCNL and 78.6% after open surgery (p = 0.537). A significant difference was observed in shorter hospital stay after PCNL (5 vs. 8.8 days, p < 0.001). Our study's limitations include its retrospective design and relatively small sample size. CONCLUSIONS: For the treatment of staghorn stones in children, PCNL was comparable to open surgery in complication and stone-free rates. PCNL had the advantage of a shorter hospital stay and open surgery showed a decreased need for multiple procedures.

13.
Arab J Urol ; 12(2): 130-6, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26019937

RESUMO

OBJECTIVES: To review our 10-year experience with uncommon testicular tumours in children (prepubertal testicular and paratesticular), to review previous reports, and to determine the appropriate management of these rare tumours, specifically the role of testicular-sparing surgery. PATIENTS AND METHODS: We retrospectively reviewed all cases of testicular tumours managed at our institution between 1999 and 2009. Boys aged <16 years were included in the study. The patients' characteristics, presentation, the diagnostic tools, tumour markers, mode of treatment, pathological findings and outcome were assessed. We reviewed previous reports that addressed testicular and paratesticular tumours in prepubertal boys, using a Medline/PubMed search. RESULTS: From 80 patients, 13 boys (median age 8.7 years) presented with testicular tumours (16%) and were included in the study. Two boys presented with precocious puberty and one with gynaecomastia. The level of α-fetoprotein was high in three boys, and the human chorionic gonadotrophin level was elevated in one, and both markers were high in one. Testicular-sparing surgery was performed in three boys. Six of the 13 tumours were malignant and seven were benign. None of the patients developed a recurrence or testicular atrophy after testicular-sparing surgery. From the review of previous reports we devised an evidence-based algorithm for managing prepubertal testicular tumours. CONCLUSIONS: Paediatric testicular tumours are rare but they require an inguinal approach for either orchidectomy or testicular-sparing surgery; we recommend the latter option as long as frozen sections are analysed and a safety margin is maintained.

14.
Urology ; 82(6): 1405-9, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24139350

RESUMO

OBJECTIVE: To evaluate the prognostic role of antenatal diagnosis of posterior urethral valves (PUVs) on ultimate renal function. METHODS: Between 1990 and 2010, 315 patients with PUVs were diagnosed and treated at 2 separate tertiary centers. Primary valve ablation was performed in all patients except 18, who underwent initial vesicostomy. Patients were divided into two groups: group 1 included 144 patients who were diagnosed antenatally, and group 2 included 171 patients with a postnatal diagnosis. Long-term functional and radiologic outcomes were assessed. RESULTS: Follow-up was a median 5.5 years (range, 2-15 years). Mean age at ablation was 2.5 years (range, 1 day-15 years). Chronic kidney disease developed at the end of follow-up in 96 patients (30%): 27 (19%) in group 1 and 69 (40%) in group 2 (P <.05). The mean nadir serum creatinine was 0.6 and 0.8 mg/dL in groups 1 and 2, respectively, and the mean final serum creatinine was 0.9 and 1.7 mg/dL, respectively (P <.05). Persistent upper tract dilatation was noted in 43% of group 1 patients and in 69% of group 2 patients (P <.05). CONCLUSION: The potential for recovering renal function is believed to be significant in patients in whom early detection of PUVs and, hence, early intervention was performed. Antenatal screening and detection of these patients might play a significant role in protecting the upper tract and reducing the incidence of chronic kidney disease.


Assuntos
Insuficiência Renal Crônica/diagnóstico , Uretra/anormalidades , Adolescente , Anti-Infecciosos/uso terapêutico , Criança , Pré-Escolar , Creatinina/sangue , Feminino , Humanos , Incidência , Lactente , Masculino , Gravidez , Diagnóstico Pré-Natal , Prognóstico , Insuficiência Renal Crônica/epidemiologia , Combinação Trimetoprima e Sulfametoxazol/uso terapêutico , Refluxo Vesicoureteral/tratamento farmacológico
15.
Urology ; 82(5): 1153-5, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23830082

RESUMO

Augmentation enterocystoplasty has been extensively used to attain high-capacity low-pressure urinary reservoirs in patients with neuropathic bladder, exstrophy-epispadias complex, valve bladder syndrome, and contracted bladder. Enterovesical fistula might occur as an early complication after enterocystoplasty. We report the case of a 16-year-old boy, who presented with chronic watery diarrhea 7 years after augmentation ileocystoplasty. A colovesical fistula was diagnosed. We discuss the clinical presentation, management plan, and operative findings.


Assuntos
Extrofia Vesical/cirurgia , Fístula Intestinal/diagnóstico , Fístula da Bexiga Urinária/cirurgia , Procedimentos Cirúrgicos Urológicos/efeitos adversos , Procedimentos Cirúrgicos Urológicos/métodos , Adolescente , Extrofia Vesical/complicações , Humanos , Fístula Intestinal/complicações , Masculino , Bexiga Urinária/fisiopatologia , Bexiga Urinária/cirurgia , Fístula da Bexiga Urinária/etiologia , Bexiga Urinaria Neurogênica/complicações , Bexiga Urinaria Neurogênica/cirurgia , Coletores de Urina
16.
Urology ; 82(2): 425-8, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23639239

RESUMO

OBJECTIVE: To study vesicoureteral reflux (VUR) resolution and risk of pyelonephritis after augmentation ileocystoplasty in a cohort of patients with noncompliant neuropathic bladder. METHODS: We reviewed data for all children who underwent augmentation ileocystoplasty for noncompliant neuropathic bladder with associated VUR between July 2002 and July 2009. All patients were kept on oral antibiotic prophylaxis. Patients were followed up with renal/bladder ultrasound and voiding cystourethrography at 3 months postoperatively and annually thereafter. RESULTS: A total of 52 patients with mean age 8.7 years (range 4-17 years) were identified. VUR was unilateral in 21 patients (40%) and bilateral in 31 patients (60%). VUR was low-grade (1-3) in 20 patients (38.5%) and high-grade (4-5) in 32 patients (61.5%). Mean follow-up duration was 27 months (range 12-80 months). VUR resolved in 35 of 52 patients (67%). Low-grade VUR resolved in 18 of 20 patients (90%), whereas high-grade reflux resolved in 17 of 32 patients (53%). This difference is statistically significant (P = .006). Although no patient with initial low-grade VUR developed pyelonephritis during follow-up, 8 of 32 patients (25%) with initial high-grade VUR developed pyelonephritis. Only 1 of 17 patients (6%) with resolved high-grade VUR developed pyelonephritis vs 7 of 15 patients (47%) with persistent high-grade VUR. Again the difference is statistically significant (P = .008). CONCLUSION: Bilateral high-grade VUR in patients with neuropathic bladder persist after bladder augmentation in nearly half of patients. Half of those develop pyelonephritis during follow-up. Therefore, at the time of bladder augmentation for noncompliant neuropathic bladder, concomitant antireflux surgery should be performed for all patients with bilateral high-grade VUR.


Assuntos
Pielonefrite/etiologia , Bexiga Urinaria Neurogênica/cirurgia , Bexiga Urinária/patologia , Bexiga Urinária/cirurgia , Refluxo Vesicoureteral/cirurgia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Íleo/cirurgia , Masculino , Tamanho do Órgão , Radiografia , Índice de Gravidade de Doença , Estruturas Criadas Cirurgicamente , Bexiga Urinaria Neurogênica/complicações , Refluxo Vesicoureteral/complicações , Refluxo Vesicoureteral/diagnóstico por imagem
17.
J Endourol ; 27(6): 693-6, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23441683

RESUMO

PURPOSE: To evaluate the long-term outcome of visual internal urethrotomy (VIU) after perineal anastomotic urethroplasty for posttraumatic pediatric posterior urethral strictures. PATIENTS AND METHODS: Data of 22 boys who had undergone internal urethrotomy for recurrent stricture after perineal anastomotic urethroplasty for posttraumatic posterior urethral strictures between 1998 and 2008 were analyzed retrospectively regarding patient age, interval between anastomotic urethroplasty and internal urethrotomy, stricture length, surgical technique, and postoperative complications. VIU was performed in patients in whom a guidewire could be passed beyond the stricture segment. The eventual surgical success was defined as asymptomatic voiding without clinical evidence of residual stricture (good flow rate and absence of residual urine). RESULTS: The mean (range) age of patients was 12.2 (3-17) years. All patients had a road traffic accident with associated pelvic fracture. The perineal approach for anastomotic urethroplasty was adopted in all. The estimated stricture length was 0.5 cm or less in 15 patients and was 0.5 to 1 cm in 7 patients. The interval between anastomotic urethroplasty and internal urethrotomy was early-after 12 weeks or less-in 13 children or late-beyond 12 weeks-in the remaining 9. The overall mean interval was 18 (5-63) weeks. In all patients, a guidewire could be passed through the strictured area. One VIU was performed in 17 patients, 2 VIU in 3 patients, while 3 VIU were performed in 2 patients. There was no extravasation reported. The mean follow-up duration was 98 (38-210) months. VIU was successful in 20 of 22 (90%) patients. All patients voided with no symptoms and were continent. CONCLUSIONS: VIU offers high success rate and can be sufficient in recurrent strictures of less than 1 cm length after anastomotic urethroplasty in children whenever a guidewire can be passed through the stricture area.


Assuntos
Uretra/lesões , Uretra/cirurgia , Estreitamento Uretral/etiologia , Estreitamento Uretral/cirurgia , Adolescente , Anastomose Cirúrgica/métodos , Criança , Pré-Escolar , Fraturas Ósseas/complicações , Humanos , Masculino , Ossos Pélvicos/lesões , Períneo , Recidiva , Estudos Retrospectivos , Resultado do Tratamento , Procedimentos Cirúrgicos Urológicos Masculinos/métodos
18.
J Urol ; 190(4 Suppl): 1468-73, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-23313201

RESUMO

PURPOSE: Previous series showed controversial differential renal function outcomes after pyeloplasty in children. However, they were limited by study power, methodology and lack of comparable end points. We determined the status of differential renal function after pyeloplasty in children in what is to our knowledge the largest series to date. MATERIALS AND METHODS: After excluding patients with renal anomalies, solitary kidney or bilateral pyeloplasty from analysis, we retrospectively identified 196 younger than 18 years who were treated with pyeloplasty between May 2002 and January 2010 and had preoperative and postoperative renal scintigraphy available. Primary outcome measures were greater than 5% improvement in baseline differential renal function and baseline weighted differential renal function at last followup. Clinical variables predicting outcome measures were determined using univariable and multivariable analyses. RESULTS: During a median followup of 12 months, mean ± SD differential renal function improved from 35.8% ± 10% to 38.7% ± 11% (p <0.001). In the poor and intermediate groups baseline differential renal function improved, while in the good group function was static postoperatively (p <0.001). The linear regression model showed that only baseline differential renal function explained the variance in baseline weighted differential renal function (ß = -0.393, p <0.001). In the Cox proportional hazards model baseline differential renal function (less than 35% HR 3.196, p <0.001 and 35% to 40% HR 2.733, p = 0.002) and cortical thickness (HR 2.114, p = 0.029) were the only predictors of a greater than 5% improvement in postoperative differential renal function. CONCLUSIONS: Renal function improves after pyeloplasty in children. Baseline differential renal function and cortical thickness predict improvement after surgery.


Assuntos
Taxa de Filtração Glomerular/fisiologia , Córtex Renal/fisiopatologia , Procedimentos Cirúrgicos Reconstrutivos/métodos , Ureter/cirurgia , Obstrução Ureteral/cirurgia , Procedimentos Cirúrgicos Urológicos/métodos , Adolescente , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Lactente , Córtex Renal/diagnóstico por imagem , Testes de Função Renal , Masculino , Período Pós-Operatório , Estudos Retrospectivos , Resultado do Tratamento , Ultrassonografia , Obstrução Ureteral/diagnóstico , Obstrução Ureteral/fisiopatologia , Urografia
19.
Urology ; 80(6): 1357-60, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23102440

RESUMO

OBJECTIVE: To evaluate the functional and morphologic outcome after open pyeloplasty for ureteropelvic junction obstruction (UPJO) in ectopic pelvic kidneys. MATERIALS AND METHODS: A retrospective review of all patients who underwent open pyeloplasty in ectopic pelvic kidneys was conducted. Records were evaluated with respect to age at presentation, preoperative imaging, surgical details, and postoperative course. Patients were followed up regularly for functional and morphologic outcome. Success was defined as symptomatic relief and radiographic improvement of obstruction at the last follow-up. RESULTS: Between 1995 and 2010, 680 patients with primary UPJO underwent open dismembered pyeloplasty at our center. Of these patients, 43 (6.3%) had UPJO in ectopic pelvic kidneys. No perioperative complications were encountered in the study group. Mean follow-up was 42 months (range, 18-90 months), and 5 patients were lost to follow-up. The overall success rate was 82.6%. Postoperative hydronephrosis was improved in 20 (52.6%), stable in 11 (29%), and worsened in 7 (18.4%). Postoperative renal function was improved in 12 (31.6%), stable in 19 (50%), and deteriorated in 7 (18.4%). Redo pyeloplasty was required in 4 patients and secondary nephrectomy in 3. Preoperative differential renal function and surgeon experience were statistically significant predictors of improvement in renal function after pyeloplasty. CONCLUSION: Open pyeloplasty for UPJO in ectopic pelvic kidneys is feasible, but varying degrees of hydronephrosis and radiologic obstruction persist after pyeloplasty that could be attributed to anatomy-related pelvocaliectasis, and so regular follow-up is warranted in this subpopulation.


Assuntos
Coristoma/complicações , Rim/anormalidades , Rim/cirurgia , Obstrução Ureteral/cirurgia , Procedimentos Cirúrgicos Urológicos/métodos , Criança , Pré-Escolar , Feminino , Humanos , Hidronefrose/etiologia , Lactente , Pelve Renal/cirurgia , Masculino , Estudos Retrospectivos , Resultado do Tratamento , Obstrução Ureteral/etiologia
20.
Curr Opin Urol ; 22(6): 457-61, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22918038

RESUMO

PURPOSE OF REVIEW: Complete penile disassembly (CPD) is a widely utilized procedure for epispadias repair. The rarity of the anomaly and limited number of patients in published series limit our ability to fully evaluate the outcome of such a technique. RECENT FINDINGS: We reviewed the literature for published data on CPD. We looked at different complications of the procedure and the main modifications to alleviate such complications. We looked at functional data on the effect of such a technique on erectile function. This review should be helpful in parents/patient counseling. Future areas for research are suggested. SUMMARY: CPD is a safe and highly successful technique for epispadias repair in infants, boys and adults. There is an ongoing concern with the procedure in neonates. The procedure has a satisfactory outcome when performed for isolated epispadias. In the exstrophy population, long-term data are required to evaluate the outcome of the technique on urinary continence and sexual functions.


Assuntos
Epispadia/cirurgia , Pênis/cirurgia , Uretra/cirurgia , Procedimentos Cirúrgicos Urológicos Masculinos , Adolescente , Adulto , Criança , Pré-Escolar , Ejaculação , Epispadia/fisiopatologia , Humanos , Lactente , Recém-Nascido , Masculino , Satisfação do Paciente , Ereção Peniana , Pênis/anormalidades , Pênis/fisiopatologia , Recuperação de Função Fisiológica , Comportamento Sexual , Disfunções Sexuais Fisiológicas/etiologia , Disfunções Sexuais Fisiológicas/fisiopatologia , Fatores de Tempo , Resultado do Tratamento , Uretra/anormalidades , Uretra/fisiopatologia , Incontinência Urinária/etiologia , Incontinência Urinária/fisiopatologia , Procedimentos Cirúrgicos Urológicos Masculinos/efeitos adversos , Adulto Jovem
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