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1.
J Biotechnol ; 145(4): 341-9, 2010 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-20045032

RESUMO

Advances in proteomic technologies have led to the creation of large-scale proteome databases that can be used to elucidate invaluable information on the dynamics of the metabolic, signaling and regulatory networks and to aid understanding of physiological changes. In particular, proteomics can have practical applications, for example, through the identification of proteins that may be potential targets for the biotechnology industry, and through the extension of our understanding of the physiological action of these proteins. In this review, we describe proteomic approaches for the discovery of targets that have potential biotechnological applications. These targets include promoters, chaperones, soluble fusion partners, anchoring motifs, and excretion fusion partners. In addition, we discuss the potential applications of proteomic techniques for the design of future bioprocesses and the optimization of existing ones. Successful applications of proteomic information have proven to have enormous value for both scientific and practical applications.


Assuntos
Bactérias/metabolismo , Biotecnologia/métodos , Proteoma/metabolismo , Proteômica
2.
Nanotechnology ; 19(43): 435302, 2008 Oct 29.
Artigo em Inglês | MEDLINE | ID: mdl-21832689

RESUMO

A simple, scalable, and cost-effective technique for controlling the growth density of ZnO nanorod arrays based on a layer-by-layer polyelectrolyte polymer film is demonstrated. The ZnO nanorods were synthesized using a low temperature (T = 90 °C), solution-based method. The density-control technique utilizes a polymer thin film pre-coated on the substrate to control the mass transport of the reactant to the substrate. The density-controlled arrays were investigated as potential field emission candidates. The field emission results revealed that an emitter density of 7 nanorods µm(-2) and a tapered nanorod morphology generated a high field enhancement factor of 5884. This novel technique shows promise for applications in flat panel display technology.

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