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Food Chem ; 275: 739-745, 2019 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-30724257


Palm mid-fraction (PMF), which has a high content of symmetric POP, was converted to asymmetric PPO (APMF) via acyl migration. After solvent fractionation, the liquid phase of acyl migrated PMF (APMF-L) was obtained and blended with hydrogenated coconut oil (HCO, 50:50, w/w) to produce a fat blend (namely, an alternative fat blend) which had reduced saturated fatty acid content while having similar melting behavior to HCO. In an alternative fat blend, the major fatty acids were lauric (27.94), palmitic (26.93) and oleic (15.75 mol%) acid. The solid fat index was quite similar to that of HCO, especially at 28-44 °C. Nevertheless, an alternative fat blend had lower saturated fatty acid content, by 18%, compared to HCO. The content of highly atherogenic myristic acid was reduced by approximately 40%. The alternative fat blend in this study could be used as a raw material for non-dairy cream with low saturated fat content.

Cromatografia Gasosa , Óleo de Coco/química , Ácidos Graxos/análise , Varredura Diferencial de Calorimetria , Óleo de Coco/metabolismo , Emulsões/química , Hidrogenação , Ácidos Láuricos/análise , Ácido Oleico/análise , Ácido Palmítico/análise , Óleos Vegetais/química , Óleos Vegetais/metabolismo
BMC Infect Dis ; 18(1): 610, 2018 Dec 03.
Artigo em Inglês | MEDLINE | ID: mdl-30509196


BACKGROUND: Environmental disinfection with continuously antimicrobial surfaces could offer superior control of surface bioburden. We sought to decide the efficacy of photocatalyst antimicrobial coating in reducing methicillin-resistant Staphylococcus aureus (MRSA) acquisition in high incidence setting. METHODS: We performed prospective cohort study involving patients hospitalized in medical intensive care unit. A titanium dioxide-based photocatalyst was coated on high touch surfaces and walls. Five months of pre-intervention data were compared with five months of post-intervention data. The incidence rates of multidrug-resistant organism acquisition and the rates of hospital-acquired blood stream infection, pneumonia, urinary tract infection, and Clostridium difficile-associated diseases were compared using Cox proportional hazards regression analysis. RESULTS: In total, 621 patients were included. There was significant decrease in MRSA acquisition rate after photocatalyst coating (hazard ratio, 0.37; 95% confidence interval, 0.14-0.99; p = 0.04). However, clinical identification of vancomycin-resistant Enterococcus spp. and multidrug-resistant Acinetobacter baumannii did not decrease significantly. The hazard of contracting hospital-acquired pneumonia during the intervention period compared to baseline period was 0.46 (95% confidence interval, 0.23-0.94; p = 0.03). CONCLUSIONS: In conclusion, MRSA rate was significantly reduced after photocatalyst coating. We provide evidence that photocatalyst disinfection can be an adjunctive measure to control MRSA acquisition in high-incidence settings. TRIAL REGISTRATION: ISRCTN Registry ( ISRCTN31972004 ). Registered retrospectively on November 19, 2018.

Materiais Revestidos Biocompatíveis/química , Infecção Hospitalar/prevenção & controle , Desinfecção/métodos , Controle de Infecções/métodos , Staphylococcus aureus Resistente à Meticilina , Infecções Estafilocócicas/prevenção & controle , Titânio/química , Adulto , Idoso , Idoso de 80 Anos ou mais , Catálise , Infecção Hospitalar/epidemiologia , Planejamento Ambiental , Feminino , Humanos , Incidência , Unidades de Terapia Intensiva/normas , Masculino , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Staphylococcus aureus Resistente à Meticilina/efeitos da radiação , Pessoa de Meia-Idade , Processos Fotoquímicos , Fotoquímica , Estudos Retrospectivos , Infecções Estafilocócicas/epidemiologia , Propriedades de Superfície