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Handb Exp Pharmacol ; 268: 367-390, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34196809


The prevalence of allergic diseases is increasing rapidly and has already reached an epidemic level. Two major drivers of this development are climate change and globalization, which both induce an increase in allergens. Concomitant climate change fosters the spreading of the latter on a global scale. The increase in allergens not only aggravates the symptoms and the degree of suffering for patients who already are allergic, but also gives rise to new cases of allergies. The distribution of allergies in society follows a steep socioeconomic gradient worldwide. According to well-established theories of justice such a distribution of the allergy burden is unfair. This fact adds a major ethical dimension and challenge to the allergy epidemic. This chapter draws on the key points of policies for allergy prevention and treatment. It shows how related programs and measures can be conceptualized and prioritized according to the principles of distributional justice.

Hipersensibilidade , Pólen , Alérgenos , Mudança Climática , Humanos , Hipersensibilidade/epidemiologia , Internacionalidade
Artigo em Alemão | MEDLINE | ID: mdl-29789892


The skin, together with gut and respiratory tract, harbor a central epithelial barrier function in regards to the interaction of an individual with the environment. Continuing exposure to environmental influences can cause epithelial barrier damages and thus pave the way for atopy development. The latter describes the tendency for allergies, i. e. hypersensitivity of the skin, intestine, and respiratory tract towards per se unharmful environmental substances.Allergies are classified as non-communicable diseases (NCDs). According to the World Health Organization (WHO), they are presently the most demanding medical challenge. Allergies are the most frequent NCDs and are characterized by a high and multi-facetted level of suffering. An enormous socio-economic burden and the urgent need for effective prevention follows as consequence. Prevention options have by no means been sufficiently used. Within the skin barrier's key function in regards to the defense of atopic diseases are so far inadequately used prevention possibilities. They are based on ambitious environmental and climatic policy that pointedly addresses the barrier disrupting environmental factors.On the basis of this proposition, the present article assigns appropriate environmental and climatic policy measures. The two main arguments for such measures are a disburdening of the healthcare system as well as a far better life quality for the affected people. They are the legitimization towards an ambitious environmental and climatic policy. For its realization an integrated approach of (allergy) prevention and environmental research is necessary. Now, campaigning for its acceptance in politics and society is an urgent matter.

Saúde Ambiental , Hipersensibilidade , Mudança Climática , Alemanha , Humanos