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1.
J Environ Manage ; 297: 113335, 2021 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-34375227

RESUMO

During the last few decades, China's transformation from a low-income country to an emerging economy causes carbon emission to rise extensively. Being the largest carbon emitter, China's continuous economic growth may inevitably cause more carbon emissions in the future. To achieve carbon neutrality targets, the country is striving to promote cleaner technologies. However, to finance these environmentally friendly projects, a well-developed financial system is a pre-requisite. This study examines the role of financial development along with output, financial risk index, renewable energy electricity and human capital on carbon emissions. This study uses updated time series data from 1988 to 2018 for China employing novel econometric approaches, i.e., Narayan and Pop unit root test with structural breaks, Maki cointegration and frequency domain causality test for long, short and medium run causality. The empirical outcome shows that improvement in financial development, renewable energy electricity, and human capital index cause to limit carbon emissions. In contrast, gross domestic product, financial risk index and structural break of 2001 increase carbon emissions. Moreover, structural break year of 2008 and financial development index reduces carbon emissions. The negative association between financial development and carbon emissions supports the positive school of thoughts of financial development that promotes a sustainable environment. This study recommends the promotion of quality human capital and green financial development along with increasing the shares of renewable energy in electricity for achieving China 2030 climate targets of reducing pollution.


Assuntos
Dióxido de Carbono , Carbono , Desenvolvimento Econômico , Eletricidade , Humanos , Energia Renovável
2.
J Environ Manage ; 295: 113119, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34216897

RESUMO

To achieve zero carbon or achieving carbon neutrality target is of great importance to many countries around the globe especially post Paris climate agreement. This study, unlike previous studies, evaluates the role of environmental policy, green innovation, composite risk index, and renewable energy R&D in achieving carbon neutrality targets for G7 economies from 1990 to 2019. The results confirmed the validity of the EKC hypothesis for G7 economies. Further, the result shows that environmental policy, green innovation, composite risk index, and renewable energy R&D help control carbon emissions. In contrast, income reveals a positive influence on environmental degradation. Furthermore, bidirectional causality has been reported in environmental policy, composite risk index, green innovation, and the CO2 emissions, while unidirectional causality running from GDP and renewable energy R&D to CO2 emissions. Based on the empirical findings, it is suggested that environmental policies should be strengthened, promote green innovation and renewable energy research and development expenditures, and political stability and institutional quality must be stabilized to lowers sectoral risks that would help a sustainable environment.


Assuntos
Desenvolvimento Econômico , Política Ambiental , Carbono , Dióxido de Carbono , Energia Renovável
3.
Huan Jing Ke Xue ; 42(7): 3215-3222, 2021 Jul 08.
Artigo em Chinês | MEDLINE | ID: mdl-34212647

RESUMO

In the present study, the spatio-temporal distribution characteristics of heavy metals (Cd, Hg, As, Pb, Cr, Cu, Ni, and Zn) in soil around 19 centralized drinking water sources in Wuhan were investigated. Single-factor and comprehensive pollution indexes were used to determine soil pollution levels. The potential ecological hazard index was employed to evaluate soil potential ecological risks. The correlation and cluster analysis were conducted to identify pollution sources. The results showed that higher concentrations of heavy metals were present in soil from centralized drinking water source located in core area than suburb area of Wuhan. The concentrations of heavy metals in soil from centralized drinking water sources near the Yangtze River were higher than that in the sites near the tributaries of the Yangtze River. The average single potential ecological risk index of Hg, As, Pb, Cr, Cu, Ni, and Zn were lower than 40, which suggests a slight potential ecological risk. The average single potential ecological risk index of Cd was 80-160, which indicates a high potential ecological risk. The average comprehensive potential ecological risk index of heavy metals in soil around centralized drinking water sources in Wuhan was 142.12, which corresponded to a slight potential ecological risk. The correlation analysis showed that the sources of Cu, Pb, and Cr were similar and came from transport. The sources of Ni, As, Cr, and Cu were similar and could be attributed to metallurgical industries. The sources of Zn, Hg, and Cr were similar and could be related to antiseptic and catalytic industries. The long-term monitoring of Wuhan Dijiao and Baishazhou waterworks indicated that the concentrations of heavy metals around centralized drinking water sources in Wuhan were markedly decreased after 2017 and that ecological risk may be further reduced in the future.


Assuntos
Água Potável , Metais Pesados , Poluentes do Solo , China , Monitoramento Ambiental , Metais Pesados/análise , Medição de Risco , Solo , Poluentes do Solo/análise
4.
Materials (Basel) ; 13(22)2020 Nov 10.
Artigo em Inglês | MEDLINE | ID: mdl-33182834

RESUMO

Titanium dioxide (TiO2), the golden standard among the photocatalysts, exhibits a varying level of photocatalytic activities (PCA) amongst the synthetically prepared and commercially available products. For commercial applications, superior photoactivity and cost-effectiveness are the two main factors to be reckoned with. This study presents the development of simple, cost-effective post-treatment processes for a less costly TiO2 to significantly enhance the PCA to the level of expensive commercial TiO2 having demonstrated superior photoactivities. We have utilized sequential calcination and ball milling (BM) post-treatment processes on a less-costlier KA100 TiO2 and demonstrated multi-fold (nearly 90 times) enhancement in PCA. The post-treated KA100 samples along with reference commercial samples (P25, NP400, and ST01) were well-characterized by appropriate instrumentation and evaluated for the PCA considering acetaldehyde photodegradation as the model reaction. Lattice parameters, phase composition, crystallite size, surface functionalities, titanium, and oxygen electronic environments were evaluated. Among post-treated KA100, the sample that is subjected to sequential 700 °C calcination and BM (KA7-BM) processes exhibited 90-fold PCA enhancement over pristine KA100 and the PCA-like commercial NP400 (pure anatase-based TiO2). Based on our results, we attribute the superior PCA for KA7-BM due to the smaller crystallite size, the co-existence of mixed anatase-srilankite-rutile phases, and the consequent multiphase heterojunction formation, higher surface area, lattice disorder/strain generation, and surface oxygen environment. The present work demonstrates a feasible potential for the developed post-treatment strategy towards commercial prospects.

5.
BMC Complement Med Ther ; 20(1): 304, 2020 Oct 08.
Artigo em Inglês | MEDLINE | ID: mdl-33032580

RESUMO

BACKGROUND: Hypertension, a major risk factor of cardiovascular mortality, is a critical issue for public health. Although Baduanjin (Eight Brocades, EB), a traditional Chinese exercise, might influence blood pressure, glucose, and lipid status, the magnitude of true effects and subgroup differences remains unclear. Therefore, we performed a systematic review of relevant randomized controlled trials (RCTs) to evaluate the effect of EB on patient-important outcomes. METHODS: We systematically searched PubMed, the Cochrane Library, Web of Science, and Chinese databases since inception until March 30, 2020. Meta-analysis was carried out using "meta" package in R 3.4.3 software. A prespecified subgroup analysis was done according to the type of comparisons between groups, and the credibility of significant subgroup effects (P < 0.05) were accessed using a five-criteria list. A GRADE evidence profile was constructed to illustrate the certainty of evidence. RESULTS: Our meta-analysis, including 14 eligible trials with 1058 patients, showed that compared with routine treatment or health education as control groups, the mean difference (MD) in systolic blood pressure (SBP) of the EB groups was - 8.52 mmHg (95%CI:[- 10.65, - 6.40], P < 0.01) and diastolic blood pressure (DBP) was - 4.65 mmHg (95%CI: [- 6.55, - 2.74], P < 0.01). For blood pressure, the evidence was, however, of low certainty because of risk of bias and inconsistency, and for the outcomes of most interest to patients (cardiovascular morbidity and mortality directly), of very low certainty (measurement of surrogate only). Subgroup analysis showed there was no significant interaction effect between different type of comparisons (SBP P = 0.15; DBP P = 0.37), so it could be easily attributed to chance. CONCLUSION: Regularly EB exercising may be helpful to control blood pressure, but the evidence is only low certainty for blood pressure and very low certainty for cardiovascular morbidity and mortality. Rigorously designed RCTs that carry out longer follow-up and address patient-important outcomes remain warranted. TRIAL REGISTRATION: PROSPERO Registration number: CRD42018095854 .


Assuntos
Pressão Sanguínea/fisiologia , Hipertensão/terapia , Qigong/métodos , Humanos , Ensaios Clínicos Controlados Aleatórios como Assunto
6.
Nanomaterials (Basel) ; 10(9)2020 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-32948034

RESUMO

Titanium dioxide (TiO2) has been extensively investigated in interdisciplinary research (such as catalysis, energy, environment, health, etc.) owing to its attractive physico-chemical properties, abundant nature, chemical/environmental stability, low-cost manufacturing, low toxicity, etc. Over time, TiO2-incorporated building/construction materials have been utilized for mitigating potential problems related to the environment and human health issues. However, there are challenges with regards to photocatalytic efficiency improvements, lab to industrial scaling up, and commercial product production. Several innovative approaches/strategies have been evolved towards TiO2 modification with the focus of improving its photocatalytic efficiency. Taking these aspects into consideration, research has focused on the utilization of many of these advanced TiO2 materials towards the development of construction materials such as concrete, mortar, pavements, paints, etc. This topical review focuses explicitly on capturing and highlighting research advancements in the last five years (mainly) (2014-2019) on the utilization of various modified TiO2 materials for the development of practical photocatalytic building materials (PBM). We briefly summarize the prospective applications of TiO2-based building materials (cement, mortar, concretes, paints, coating, etc.) with relevance to the removal of outdoor/indoor NOx and volatile organic compounds, self-cleaning of the surfaces, etc. As a concluding remark, we outline the challenges and make recommendations for the future outlook of further investigations and developments in this prosperous area.

7.
Glycoconj J ; 37(3): 373-394, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32103424

RESUMO

Currently, the definitive diagnosis in breast cancer requires biopsy and histopathology, such the most effective markers are tissue-based. However, the advantages of saliva in collection and storage make it possible for assessing human pathology and contributing to the development of cancer-related biomarkers for clinical application. The present study validated alteration of salivary protein glycopatterns recognized by Bandeiraea simplicifolia lectin I (BS-I) in the saliva of patients with breast diseases using saliva microarrays, and the N/O-glycan profiles of their salivary glycoproteins isolated by the BS-I-magnetic particle conjugates from 259 female subjects (66 healthy volunteers (HV), 65 benign breast cyst or tumor patients (BB), 66 patients with breast cancer in stage I (BC-I) and 62 patients with breast cancer in stage II (BC-II)) were analyzed by MALDI-TOF/TOF-MS. The results showed that the expression level of galactosylated glycans recognized by BS-I was significantly increased in patients with breast cancer compared with HV (p < 0.05). Totally, there were 11/10, 10/19, 7/24 and 7/9 galactosylated N-/O-linked glycans were identified and annotated from the pooled salivary samples of HV, BB, BC-I and BC-II, respectively. One galactosylated N-glycan peak (m/z 2773.977), and 4 galactosylated O-glycan peaks (m/z 868.295, 882.243, 884.270 and 1030.348) were found only in BC-I. These findings could provide pivotal information on galactosylated N/O-linked glycans related to breast cancer, and promote the study of biomarkers for early-stage breast cancer based on precise alterations of galactosylated N/O-glycans in saliva.

8.
Food Chem Toxicol ; 135: 110973, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31738983

RESUMO

The construction, expression and functional analysis of codon-optimized single-chain variable fragment (coscFv) against clenbuterol (CBL) prepared from the Escherichia coli system is described. First, the ionic concentration for coscFv expression was optimized through single-factor experiments. Then, the extraction conditions of inclusion bodies were optimized, and coscFv was affinity-purified. Finally, the functional analysis of coscFv was elucidated by indirect competitive enzyme-linked immunosorbent assay (icELISA) and molecular docking. After optimizing the ionic concentration, the yield of coscFv increased from 21.69% to 23.26%. The molecular weight of coscFv was determined to be approximately 27 kDa according to the SDS-PAGE and Western blot assay. The percentage of coscFv was as high as 43.9% after the inclusion bodies were extracted, washed, and dissolved. Functional analysis indicated that the coscFv recognized CBL, and the 50% inhibition average concentration of CBL (IC50) was 4.22 ± 0.01 (n = 3) ng/mL. The binding site between coscFv and CBL consisted of Asp33H, Met34H, Ser50H, Arg52H, Tyr57H, Leu59H, Asp99H, and Tyr93L. Our study confirms that coscFv can bind with CBL through the key amino acid residues and can be used to sensitively detect CBL.


Assuntos
Agonistas Adrenérgicos beta/imunologia , Clembuterol/imunologia , Anticorpos de Cadeia Única/imunologia , Agonistas Adrenérgicos beta/metabolismo , Sequência de Aminoácidos , Sítios de Ligação , Clembuterol/metabolismo , Clonagem Molecular/métodos , Ensaio de Imunoadsorção Enzimática , Escherichia coli/genética , Simulação de Acoplamento Molecular , Ligação Proteica , Proteínas Recombinantes/genética , Proteínas Recombinantes/imunologia , Proteínas Recombinantes/metabolismo , Alinhamento de Sequência , Anticorpos de Cadeia Única/genética , Anticorpos de Cadeia Única/metabolismo
9.
Braz J Med Biol Res ; 51(5): e6632, 2018 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-29561953

RESUMO

The aim of this study was to find related pathogenic genes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy in (CADASIL)-like patients. The direct sequencing and high-throughput multiplex polymerase chain reaction (PCR) was performed to screen for related genes. The clinical and imaging data of a CADASIL-like patient (the pro-band) and his family members were collected. At first, the known hereditary cerebral vascular genes of the pro-band were screened with direct sequencing to find candidate gene mutations. High-throughput multiplex PCR was then used to analyze the single nucleotide polymorphism of the candidate gene in the family members. The results showed that there was missense mutation of the high temperature requirement protease A1 (HTRA1) gene in the pro-band, which may be a pathogenic factor according to the biological software analysis. The following SNP results revealed that the other family members also had the HTRA1 gene mutation. Thus, the CADASIL-like family disease may be caused by heterozygous HTRA1 gene mutation, which leads to autosomal dominant hereditary cerebral small vessel disease.


Assuntos
CADASIL/genética , Serina Peptidase 1 de Requerimento de Alta Temperatura A/genética , Mutação de Sentido Incorreto/genética , Adulto , Feminino , Predisposição Genética para Doença , Genótipo , Heterozigoto , Humanos , Masculino , Reação em Cadeia da Polimerase Multiplex , Linhagem , Polimorfismo de Nucleotídeo Único
10.
Braz. j. med. biol. res ; 51(5): e6632, 2018. graf
Artigo em Inglês | LILACS | ID: biblio-889075

RESUMO

The aim of this study was to find related pathogenic genes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy in (CADASIL)-like patients. The direct sequencing and high-throughput multiplex polymerase chain reaction (PCR) was performed to screen for related genes. The clinical and imaging data of a CADASIL-like patient (the pro-band) and his family members were collected. At first, the known hereditary cerebral vascular genes of the pro-band were screened with direct sequencing to find candidate gene mutations. High-throughput multiplex PCR was then used to analyze the single nucleotide polymorphism of the candidate gene in the family members. The results showed that there was missense mutation of the high temperature requirement protease A1 (HTRA1) gene in the pro-band, which may be a pathogenic factor according to the biological software analysis. The following SNP results revealed that the other family members also had the HTRA1 gene mutation. Thus, the CADASIL-like family disease may be caused by heterozygous HTRA1 gene mutation, which leads to autosomal dominant hereditary cerebral small vessel disease.


Assuntos
Humanos , Masculino , Feminino , Adulto , Mutação de Sentido Incorreto/genética , CADASIL/genética , Serina Peptidase 1 de Requerimento de Alta Temperatura A/genética , Linhagem , Predisposição Genética para Doença , Polimorfismo de Nucleotídeo Único , Reação em Cadeia da Polimerase Multiplex , Genótipo , Heterozigoto
11.
Pharm Biol ; 52(6): 681-7, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24824320

RESUMO

CONTEXT: Alismatis rhizome (RA) (Water Plantain Family, also called "Zexie" in Chinese), one of the commonly used components of traditional Chinese medicines, is derived from the dried rhizomes of Alisma orientalis (Sam.) Juzep. (Alismataceae). OBJECTIVE: This study explores the RA influences on rat cytochrome P450 (CYP) enzymes (CYP1A2, CYP2C9, CYP2E1 and CYP3A4) by using cocktail probe drugs in vivo. MATERIALS AND METHODS: A cocktail solution at a dose of 5 mL/kg, which contained phenacetin (20 mg/kg), tolbutamide (5 mg/kg), chlorzoxazone (20 mg/kg) and midazolam (10 mg/kg), was orally administration to rats treated twice daily with RA (10, 20 and 40 g/kg) for consecutive 14 days. Blood samples (0.2 mL) were collected at a series of time-points and the concentrations of probe drugs in plasma were determined by HPLC-MS/MS. The corresponding pharmacokinetic parameters were calculated by the software of DAS 2.0 (Wenzhou Medical College, Zhejiang, China). RESULTS: In the experiment, there was a statistically significant difference in the t1/2, Cmax, AUC(0-∞) and CL for phenacetin and midazolam, while there was no statistical pharmacokinetics difference for tolbutamide and chlorzoxazone. Our study showed that treatment with multiple doses of RA had an inductive effect on rat CYP1A2 and an inhibitory effect on rat CYP3A4 enzyme activity. However, RA has no inductive or inhibitory effect on the activities of CYP2C9 and CYP2E1. CONCLUSIONS: Caution is needed when RA is co-administration with some CYP1A2 or CYP3A4 substrates in clinic, because it may result in treatment failure and herb-drug interactions.


Assuntos
Alisma , Sistema Enzimático do Citocromo P-450/metabolismo , Medicamentos de Ervas Chinesas/farmacologia , Rizoma , Animais , Medicamentos de Ervas Chinesas/isolamento & purificação , Indução Enzimática/efeitos dos fármacos , Indução Enzimática/fisiologia , Inibidores Enzimáticos/isolamento & purificação , Inibidores Enzimáticos/farmacologia , Masculino , Ratos , Ratos Sprague-Dawley , Resultado do Tratamento
12.
Eur J Radiol ; 81(10): 2576-84, 2012 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-22138121

RESUMO

BACKGROUND: Real-time elastography (RTE), as a non-invasive method, is used for the classification of benign and malignant lymph nodes (LNs) and developed as an alternative to biopsy. Elasticity score (ES) and strain ratio (SR) are used for the interpretation of RTE. We studied the performance of RTE for diagnosis of malignant LNs using meta-analysis. METHODS: PubMed, the Cochrane Library, ISI Web of Knowledge, China National Knowledge Infrastructure were searched. The studies published in English or Chinese relating to the diagnostic value of RTE for superficial LNs were collected. Hierarchical summary receiver operating characteristic (HSROC) curve was used to examine the RTE accuracy. Clinical utility of RTE for LNs was evaluated by Fagan plot analysis. RESULTS: A total of 9 studies which included 835 LNs were analyzed. The summary sensitivity and specificity for the diagnosis of malignant LNs were 0.74 (95% confidence interval (CI), 0.66-0.81) and 0.90 (95% CI, 0.82-0.94) for ES, and 0.88 (95% CI, 0.79-0.93) and 0.81 (95% CI, 0.49-0.95) for SR, respectively. Compared to ES, SR obviously improved the diagnostic sensitivity value. The HSROCs were 0.88 for ES and 0.91 for SR, respectively. After RTE results over the cut-off value for malignant LNs ("positive" result), the corresponding post-test probability for the presence (if pre-test probability was 50%) was 88% for ES and 82% for SR, respectively; while, in "negative" measurement, the post-test probability was 22% and 13%, respectively. CONCLUSION: RTE has a high accuracy in the classification of superficial LNs and can potentially help to select suspicious LNs for biopsy.


Assuntos
Técnicas de Imagem por Elasticidade/métodos , Técnicas de Imagem por Elasticidade/estatística & dados numéricos , Linfonodos/diagnóstico por imagem , Metástase Linfática/diagnóstico por imagem , Sistemas Computacionais , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
14.
J Trauma ; 65(1): 116-22, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18580519

RESUMO

BACKGROUND: The mechanism of injury in dorsal dislocation is usually a hyperextensive stress simultaneous with some degree of longitudinal compression. Operative treatment is indicated for those unstable and reduction is not achieved. We report the surgical outcome of volar plate arthroplasty of the proximal interphalangeal (PIP) joint using the Mitek Micro GII suture anchor. METHODS: We reviewed the medical records of 20 patients with acute or chronic dorsal dislocation or subluxation of the PIP joint who were managed using the Mitek Micro GII suture anchor over the past 5 years by the same surgeon (J.T.S.). Fourteen patients had acute injuries (<4 weeks before surgery) and six patients had chronic injuries (average interval of 4.1 week from injury to surgery; range, 1-8 weeks). The patients had persistent pain and loss of range of motion after trauma, and the reductions were still unstable. RESULTS: All patients were evaluated an average of 25 months postoperatively (range, 12-30 months). The average arc of motion of the PIP joints of the fingers was 82 degrees . There were no obvious perioperative complications, and no patient reported pain at rest or with activity. CONCLUSION: Volar plate arthroplasty using the Mitek Micro GII suture anchor is an effective treatment choice for acute or chronic PIP joint dorsal dislocation or subluxation.


Assuntos
Artroplastia/instrumentação , Articulações dos Dedos , Luxações Articulares/cirurgia , Placa Palmar , Âncoras de Sutura , Adolescente , Adulto , Estudos de Coortes , Feminino , Humanos , Luxações Articulares/diagnóstico por imagem , Luxações Articulares/fisiopatologia , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Radiografia , Amplitude de Movimento Articular , Recuperação de Função Fisiológica , Estudos Retrospectivos , Resultado do Tratamento
15.
J Orthop Surg Res ; 3: 16, 2008 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-18435845

RESUMO

BACKGROUND: The purpose of the study is to retrospectively review the clinical outcome of our study population of middle-aged RA patients who had suffered extensor-tendon rupture. We reported the outcome of autogenous palmaris tendon grafting of multiple extensor tendons at wrist level in 14 middle-aged rheumatoid patients. METHODS: Between Feb. 2000 to Feb. 2004, thirty-six ruptured wrist level extensor tendons were reconstructed in fourteen rheumatoid patients (11 women and three men) using autogenous palmaris longus tendon as a free interposition graft. In each case, the evaluation was based on both subjective and objective criteria, including the range of MCP joint flexion after surgery, the extension lag at the metacarpophalangeal joint before and after surgery, and the ability of the patient to work. RESULTS AND DISCUSSION: The average of follow-up was 54.1 months (range, 40 to 72 months). The average range of MCP joint flexion after reconstruction was 66 degrees . The extension lag at the metacarpophalangeal joint significantly improved from a preoperative mean of 38 degrees (range, 25 degrees -60 degrees ) to a postoperative mean of 16 degrees (range, 0 degrees -30 degrees ). Subjectively all patients were satisfied with the clinical results, and achieved a return to their level of ability before tendon rupture. We found good functional results in our series of interposition grafting using palmaris longus to reconstruct extensor tendon defects in the rheumatoid patients. CONCLUSION: Reconstruction for multiple tendon ruptures is a salvage procedure that is often associated with extensor lag and impairment of overall function. Early aggressive treatment of extensor tendon reconstruction using autogenous palmaris longus tendon as a free interposition graft in the rheumatoid wrist is another viable option to achieve good clinical functional result.

16.
Arthroscopy ; 21(5): 620-6, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15891731

RESUMO

PURPOSE: This study used percutaneous techniques augmented by simultaneous wrist arthroscopy to visualize the fracture and thus confirm the fracture alignment and reduction and also to assesses the concurrent associated ligament injuries. TYPE OF STUDY: Retrospective study. METHODS: Arthroscopy was used to help to reduce scaphoid fractures and assess soft-tissue injuries in 15 acute cases (13 male and 2 female patients). The fractures were treated by reduction under arthroscopic control and percutaneous fixation with the cannulated interosseous compression screw. Soft-tissue lesions were also treated at the same time using debridement, suture repair, or K-wire transfixation. The average age of the patients was 29.2 years (range, 19 to 48 years). RESULTS: Two patients (13.3%) had scapholunate (SL) ligament injuries, and both exhibited partial tear of the SL ligament. Four patients (26.7%) suffered lunotriquetral (LT) ligament injuries and received ligament debridement, K-wire fixation of the LT joint, and splinting. Six patients (40%) had chondral fractures. Additionally, the triangular fibrocartilage complex (TFCC) was torn in 5 patients (33%). Finally, 5 patients (33%) suffered radioscaphocapitate ligament or long radiolunate ligament injuries. All fractures healed without malunion or nonunion and, at follow-up of 24 to 28 months, 11 patients had excellent results and 4 had good results based on Mayo Modified Wrist Scores. CONCLUSIONS: We believe that arthroscopic reduction may be considered for scaphoid fractures because this approach can use a single procedure to achieve acceptable restoration of fractures as well as assessment and management of soft-tissue lesions. LEVEL OF EVIDENCE: Level IV Therapeutic Study, case series with no, or historical, control group.


Assuntos
Fixadores Externos , Fraturas Ósseas/cirurgia , Osso Escafoide/lesões , Osso Escafoide/cirurgia , Adulto , Artroscopia/métodos , Fibrocartilagem/lesões , Fibrocartilagem/cirurgia , Seguimentos , Humanos , Ligamentos/lesões , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
17.
J Chin Med Assoc ; 66(7): 423-8, 2003 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-14509405

RESUMO

BACKGROUND: The tibial pilon fracture is a relatively uncommon but a most difficult fracture to manage. Most orthopedic surgeons agree that the goal of treating such kind of fracture should be anatomic restoration of the articular surface, rigid and stable fixation, early restoration of joint motion, and finally, good functional recovery. We report our experience in managing the fracture and evaluate the operative results for patients who were treated with the Link May Anatomic Bone Plate. METHODS: A retrospective study was performed for tibial pilon fracture from January 1997 to February 2000. A total of thirty patients underwent surgical treatment using Link Distal Fibular Anatomic May Bone Plate, including twenty males and ten females with an average age of 42.6 years (range, 18 to 88 years). According to Rüedi-Allgöwer classification, the fracture patterns were type I in 30% (n = 9), type II in 53.3% (n = 16), and type III in 16.7% (n = 5). Twenty-two fractures (73.3%) were closed type; three (10%) were classified (Gustilo) as grade I open fracture; and five (16.7%) as grade II open fracture. Associated injuries included multiple fractures in five cases and head injury in four cases. All patients were evaluated clinically and radiologically after a mean time of 27.1 months (range, 17 to 39 months). RESULTS: Satisfactory results were obtained in 83.3% of cases. Complications were found in four patients (13.3%), with one nonunion, two superficial wound infections and one deep wound infection. CONCLUSIONS: We concluded that this plating system is one choice of treatment for tibial pilon fracture which provides relatively good outcome.


Assuntos
Placas Ósseas , Fraturas da Tíbia/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento
18.
Hand Surg ; 8(2): 173-8, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15002093

RESUMO

Scapholunate (SL) instability is the most common cause of carpal instability. Pre-dynamic and dynamic type SL instability is difficult to diagnose and treat. This series reviews 17 soldiers with pre-dynamic or dynamic SL instability diagnosed by midcarpal arthroscopy and treated with dorsal capsulodesis and augmentation ligamentoplasty with partial dorsal radiocarpal (DRC) ligament procedure between 1997 and 2000. The sample included 14 males and three females. The dominant hand was involved in 15 patients. Moreover, the average patient age was 29.3 years (range 19-36 years). The diagnosis was based on clinical and arthroscopic criteria. Fifteen patients were followed up at our clinic regularly, with the follow-up period ranging from 12 to 39 months (mean 25.2 months). Fourteen patients had excellent or good results, and one patient had poor result based on Mayo Modified Wrist Score. Wrist motion in the flexion-extension plane loss averaged 18.4 degrees. Grip force increased significantly following treatment, with improvement totaling 15% of normal side. No complications were found in this series. Consequently, dorsal capsulodesis and ligamentoplasty with partial DRC ligament is considered a valuable therapeutic option for cases of pre-dynamic and dynamic SL instability.


Assuntos
Cápsula Articular/cirurgia , Instabilidade Articular/cirurgia , Ligamentos Articulares/cirurgia , Osso Semilunar/cirurgia , Osso Escafoide/cirurgia , Articulação do Punho/cirurgia , Adulto , Artroscopia , Ossos do Carpo/cirurgia , Feminino , Humanos , Instabilidade Articular/diagnóstico , Masculino , Militares , Resultado do Tratamento
19.
J Orthop Surg (Hong Kong) ; 8(1): 1-8, 2000 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12468868

RESUMO

From September 1996 to September 1997, 27 adult patients were diagnosed with chronic triangular fibrocartilage complex (TFCC) tears with distal radioulna joint (DRUJ) instability in our clinic. They all received the procedure of TFCC reconstruction with partial extensor carpi ulnaris (ECU) tendon combined with or without ulnar shortening. There were 26 males and one female in the study with a mean age of 22.4 years. The follow-up period ranged from 22 to 28 months with a mean of 26.2 months. 24 patients who had positive or zero ulnar variance received the procedure of ulnar shortening. Three patients who had minus ulnar variance only received TFCC reconstruction. After the operation, the DRUJ was fixed by a 2.0 mm K-wire for 4 weeks. All patients underwent a rehabilitation program and they were reexamined at our outpatient department (OPD). The results were graded according to the Mayo Modified Wrist Score. Five of the 27 patients rated their wrists 'excellent', 18 rated 'good', and 4 rated 'fair. Overall, a total of 23 patients (85%) rated satisfactorily and returned to work or sport activities. In the 4 patients rated 'fair', mild pain at work and/or exercise, and mildly limited supination were found; however their grip strength was improved at least by 65% compared to the opposite hand. Therefore, as suggested by this study, TFCC reconstruction with partial ECU tendon combined with the ulnar shortening procedure is an alternative method for chronic TFCC tears with DRUJ instability.

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