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1.
Heart Rhythm ; 17(2): 238-242, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31476412

RESUMO

BACKGROUND: Complete tumor resection is a standard strategy in the surgical treatment of ventricular tachycardia (VT) associated with cardiac tumors. Recently, an intraoperative electroanatomic mapping system (CARTO) has enabled surgeons to target the localized arrhythmogenic substrate for partial resection and/or cryoablation in nonresectable cardiac tumors. OBJECTIVE: The purpose of this study was to evaluate the surgical procedures and late outcomes of the treatment of VT associated with cardiac tumors. METHODS: We examined six patients (age 1-65 years) who had undergone surgical treatment of VT associated with cardiac tumors between 2010 and 2016. The 4 pathologies of the cardiac tumors were lipoma 2, fibroma 2, hemangioma 1, and lymphoma 1. Intraoperative epicardial mapping using CARTO was performed in 5 patients(80%). Surgical procedures and long-term outcomes were evaluated. RESULTS: Arrhythmogenic substrates with abnormal electrograms, such as fractionated or late potential, were identified locally or circumferentially beside the tumor in every patient. Complete tumor resection with cryoablation was performed in 3 patients. Two patients underwent partial tumor resection with cryoablation. Cryoablation without tumor resection was performed in 1 patient. No mortality and morbidity occurred. Additional catheter ablation was required in 2 patients to treat occurrence of nonclinical VT and induction of clinical VT during hospital stay. Mean follow-up time was 90 ± 52.5 months. There was no recurrence of clinical VT. CONCLUSION: The outcomes of surgical treatment of VT associated with cardiac tumors were excellent. Intraoperative CARTO mapping was beneficial to eliminate the VT substrates associated with nonresectable cardiac tumors.

3.
Jpn J Radiol ; 38(1): 77-84, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31664664

RESUMO

PURPOSE: To present long-term results obtained with endovascular abdominal aortic aneurysm (AAA) repair (EVAR) using the Zenith AAA endovascular graft from a single institution. MATERIALS AND METHODS: Between 2007 and 2013, 95 consecutive patients (median age 77 years) underwent EVAR using Zenith. Data were prospectively collected and retrospectively analyzed until 2019. Primary outcomes were overall survival, freedom from AAA rupture, and freedom from AAA-related death. Secondary outcomes were freedom from late (> 30 days) re-intervention and surgical conversion, and freedom from aneurysm sac growth (> 5 mm). RESULTS: The initial technical success rate was 96.8%. There were no deaths or intraoperative conversions. Overall survival at 1, 3, 5, and 10 years was 90.8%, 81.7%. 74.3%, and 57.2%, respectively. AAA rupture occurred in one patient (1.1%). Freedom from AAA-related death was 100% during the follow-up period. Freedom from aneurysm sac growth at 1, 3, 5, and 10 years was 98.8%, 86.4%, 76.9%, 53.0%, respectively. Freedom from late re-intervention and open surgical conversion at 1, 3, 5, and 10 years was 98.9%, 88.9%, 86.7, and 57.9%, respectively. CONCLUSION: EVAR with Zenith endografts represents a safe and durable means of AAA repair, and risk of rupture and aneurysm-related death are low.

4.
J Magn Reson Imaging ; 51(1): 183-194, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31044459

RESUMO

BACKGROUND: H2 15 O-positron emission tomography (PET) is considered the reference standard for absolute cerebral blood flow (CBF). However, this technique requires an arterial input function measured through continuous sampling of arterial blood, which is invasive and has limitations with tracer delay and dispersion. PURPOSE: To demonstrate a new noninvasive method to quantify absolute CBF with a PET/MRI hybrid scanner. This blood-free approach, called PC-PET, takes the spatial CBF distribution from a static H2 15 O-PET scan, and scales it to the whole-brain average CBF value measured by simultaneous phase-contrast MRI. STUDY TYPE: Observational. SUBJECTS: Twelve healthy controls (HC) and 13 patients with Moyamoya disease (MM) as a model of chronic ischemic disease. FIELD STRENGTH/SEQUENCES: 3T/2D cardiac-gated phase-contrast MRI and H2 15 O-PET. ASSESSMENT: PC-PET CBF values from whole brain (WB), gray matter (GM), and white matter (WM) in HCs were compared with literature values since 2000. CBF and cerebrovascular reactivity (CVR), which is defined as the percent CBF change between baseline and post-acetazolamide (vasodilator) scans, were measured by PC-PET in MM patients and HCs within cortical regions corresponding to major vascular territories. Statistical Tests: Linear, mixed effects models were created to compare CBF and CVR, respectively, between patients and controls, and between different degrees of stenosis. RESULTS: The mean CBF values in WB, GM, and WM in HC were 42 ± 7 ml/100 g/min, 50 ± 7 ml/100 g/min, and 23 ± 3 ml/100 g/min, respectively, which agree well with literature values. Compared with normal regions (57 ± 23%), patients showed significantly decreased CVR in areas with mild/moderate stenosis (47 ± 17%, P = 0.011) and in severe/occluded areas (40 ± 16%, P = 0.016). Data Conclusion: PC-PET identifies differences in cerebrovascular reactivity between healthy controls and cerebrovascular patients. PC-PET is suitable for CBF measurement when arterial blood sampling is not accessible, and warrants comparison to fully quantitative H2 15 O-PET in future studies. LEVEL OF EVIDENCE: 3 Technical Efficacy Stage: 2 J. Magn. Reson. Imaging 2019. J. Magn. Reson. Imaging 2020;51:183-194.

5.
ACS Omega ; 4(2): 2547-2553, 2019 Feb 28.
Artigo em Inglês | MEDLINE | ID: mdl-31459492

RESUMO

We prepared iodine molecules encapsulated in single-walled carbon nanotubes (I@SWCNTs) by electro-oxidation of iodide ions with empty SWCNT electrode. Li-ion battery electrode properties of I@SWCNTs were investigated. It was found that the I@SWCNT sample can catch and release Li ions reversibly. We performed Raman measurements to reveal the Li-ion storage mechanism of I@SWCNT. It is plausible that chemical reactions of I2 from/into LiI in SWCNTs occur during Li-ion charging/discharging of I@SWCNT. We also prepared the CsI@SWCNT sample to verify that alkali metal ions can be extracted from alkali metal halide in SWCNTs. The extraction of cesium ions from CsI@SWCNT was confirmed by Raman measurements. It was also found that I@SWCNT can work as a Li-ion battery electrode in solid electrolyte as well.

6.
J Orthop Sci ; 2019 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-31350063

RESUMO

BACKGROUND: Lateral thrust is known to be risk factors for knee osteoarthritis progression. Medial meniscus extrusion is also known to be risk factors for knee osteoarthritis progression; moreover, the amount of change in medial meniscus extrusion from non-weight bearing to weight bearing is an important factor for the progression of knee osteoarthritis. This study aimed to investigate the correlation between lateral thrust and the change in medial meniscus extrusion. METHODS: In total, 44 knees from 44 patients (mean age, 68.9 years) with knee osteoarthritis were divided into two groups according to the Kellgren-Lawrence grade: early-stage osteoarthritis (Kellgren-Lawrence = 2) and severe osteoarthritis (Kellgren-Lawrence = 3 or 4). The lateral thrust during gait, represented as the lateral acceleration peak immediately after heel strike, was recorded by an inertial sensor. The amount of change in medial meniscus extrusion, which was the difference between weight-bearing (unipedal standing) and non-weight-bearing (supine) conditions, was evaluated using ultrasonography. RESULTS: The mean value of the lateral acceleration peak in the severe osteoarthritis group was higher than that of the early-stage osteoarthritis group (p < 0.05). The non-weight-bearing and weight-bearing medial meniscus extrusion in the severe OA group were significantly higher than those of the early-stage osteoarthritis group (p < 0.001). However, the amount of change in medial meniscus extrusion in severe osteoarthritis group was significantly lower than in the early-stage osteoarthritis group (p < 0.05). The amount of change in medial meniscus extrusion showed a significant correlation with the lateral acceleration peak in the early-stage osteoarthritis group (r = 0.56, p < 0.001). On the other hand, there was no significant correlation in the severe osteoarthritis group. CONCLUSION: The lateral thrust shows a positive correlation with the amount of change in medial meniscus extrusion by weight bearing in patients with early-stage knee osteoarthritis.

8.
J Stroke Cerebrovasc Dis ; 28(5): 1371-1380, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30803784

RESUMO

BACKGROUND AND PURPOSE: Therapeutic indications for recombinant tissue plasminogen activator therapy and endovascular therapy need to be assessed for patients with hyperacute ischemic stroke. We investigated the relationship between the minimum apparent diffusion coefficient ratios in each Alberta Stroke Program Early CT Score region and reversible lesion in patients with hyperacute ischemic stroke receiving recombinant tissue plasminogen activator therapy and/or treated with endovascular therapy. MATERIALS AND METHODS: We retrospectively evaluated 29 patients with first ischemic stroke due to stenosis/occlusion of the internal carotid artery or horizontal portion of the middle cerebral artery that was successfully recanalized by recombinant tissue plasminogen activator therapy and/or treated with endovascular therapy. We measured the minimum apparent diffusion coefficient value in each Alberta Stroke Program Early CT Score region (11 regions) and calculated the ratio. RESULTS: There was a significant difference in minimum apparent diffusion coefficient ratios between regions that included and did not include infarction (P < .0001), which were distinguishable with a cutoff value of .808 (area under the curve = .80, P < .001). A statistical difference in the proportion of infarction with the cutoff value was observed between patients treated with endovascular therapy and receiving recombinant tissue plasminogen activator therapy alone (9.9% versus 24.6%, P = .0041) and between patients with affected middle cerebral and internal carotid arteries (7.0% versus 24.2%, P = .0002). The lowest apparent diffusion coefficient ratio was associated with the time to recombinant tissue plasminogen activator injection. CONCLUSIONS: Minimum apparent diffusion coefficient ratios in Alberta Stroke Program Early CT Score regions are useful in predicting therapeutic effect.


Assuntos
Artéria Carótida Interna/diagnóstico por imagem , Estenose das Carótidas/diagnóstico por imagem , Tomada de Decisão Clínica , Imagem de Difusão por Ressonância Magnética , Infarto da Artéria Cerebral Média/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Idoso , Idoso de 80 Anos ou mais , Artéria Carótida Interna/fisiopatologia , Estenose das Carótidas/fisiopatologia , Estenose das Carótidas/terapia , Procedimentos Endovasculares , Feminino , Fibrinolíticos/administração & dosagem , Humanos , Infarto da Artéria Cerebral Média/fisiopatologia , Infarto da Artéria Cerebral Média/terapia , Masculino , Pessoa de Meia-Idade , Seleção de Pacientes , Valor Preditivo dos Testes , Estudos Retrospectivos , Terapia Trombolítica , Fatores de Tempo , Tempo para o Tratamento , Ativador de Plasminogênio Tecidual/administração & dosagem , Resultado do Tratamento
9.
Stroke ; 50(2): 373-380, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30636572

RESUMO

Background and Purpose- Noninvasive imaging of brain perfusion has the potential to elucidate pathophysiological mechanisms underlying Moyamoya disease and enable clinical imaging of cerebral blood flow (CBF) to select revascularization therapies for patients. We used hybrid positron emission tomography (PET)/magnetic resonance imaging (MRI) technology to characterize the distribution of hypoperfusion in Moyamoya disease and its relationship to vessel stenosis severity, through comparisons with a normative perfusion database of healthy controls. Methods- To image CBF, we acquired [15O]-water PET as a reference and simultaneously acquired arterial spin labeling (ASL) MRI scans in 20 Moyamoya patients and 15 age-matched, healthy controls on a PET/MRI scanner. The ASL MRI scans included a standard single-delay ASL scan with postlabel delay of 2.0 s and a multidelay scan with 5 postlabel delays (0.7-3.0s) to estimate and account for arterial transit time in CBF quantification. The percent volume of hypoperfusion in patients (determined as the fifth percentile of CBF values in the healthy control database) was the outcome measure in a logistic regression model that included stenosis grade and location. Results- Logistic regression showed that anterior ( P<0.0001) and middle cerebral artery territory regions ( P=0.003) in Moyamoya patients were susceptible to hypoperfusion, whereas posterior regions were not. Cortical regions supplied by arteries with stenosis on MR angiography showed more hypoperfusion than normal arteries ( P=0.001), but the extent of hypoperfusion was not different between mild-moderate versus severe stenosis. Multidelay ASL did not perform differently from [15O]-water PET in detecting perfusion abnormalities, but standard ASL overestimated the extent of hypoperfusion in patients ( P=0.003). Conclusions- This simultaneous PET/MRI study supports the use of multidelay ASL MRI in clinical evaluation of Moyamoya disease in settings where nuclear medicine imaging is not available and application of a normative perfusion database to automatically identify abnormal CBF in patients.


Assuntos
Bases de Dados Factuais , Imagem por Ressonância Magnética , Artéria Cerebral Média , Doença de Moyamoya , Tomografia por Emissão de Pósitrons , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Artéria Cerebral Média/diagnóstico por imagem , Artéria Cerebral Média/fisiopatologia , Doença de Moyamoya/diagnóstico por imagem , Doença de Moyamoya/fisiopatologia , Marcadores de Spin
10.
J Orthop Sci ; 24(2): 207-213, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30322623

RESUMO

BACKGROUND: Lumbar alignment of posterior or anterior tilts affects the exacerbation and remission of symptoms of lumbar spinal stenosis patients. This study aimed to clarify the correlation between spinal and pelvic movements during gait and the aggravation of low back pain after gait loading in lumbar spinal stenosis patients. METHODS: A total of 29 patients with lumbar spinal stenosis completed leg and low back pain assessments and gait analysis before and after gait loading tests. Patients were divided into leg and low back pain change (n = 8), leg pain only change (n = 12), and non-change (n = 9) groups based on the differences of leg and low back pain between before and after the tests. Peak kinematic values of the anterior tilts of the trunk, thoracic spine, lumbar spine, and pelvis during the stance phase were obtained via three-dimensional gait analysis. RESULTS: In the leg and low back pain change group, the anterior lumbar and pelvic tilts were larger after than before the tests; however, in the leg pain only change and non-change groups, only the anterior lumbar tilt was larger after than before the tests. Anterior lumbar tilt before and after the tests negatively correlated with the aggravation of low back pain, and an increase in the anterior pelvic tilt positively correlated with the aggravation of low back pain. CONCLUSIONS: In lumbar spinal stenosis patients, smaller anterior lumbar tilt and larger anterior pelvic tilt during gait loading may affect the aggravation of low back pain by gait loading. Increasing in lumbar lordosis during gait might be one of the factors leading to low back pain in lumbar spinal stenosis patients.


Assuntos
Avaliação da Deficiência , Marcha/fisiologia , Dor Lombar/fisiopatologia , Vértebras Lombares , Equilíbrio Postural/fisiologia , Estenose Espinal/complicações , Adulto , Idoso , Fenômenos Biomecânicos , Estudos de Coortes , Progressão da Doença , Feminino , Humanos , Dor Lombar/etiologia , Masculino , Pessoa de Meia-Idade , Ossos Pélvicos , Postura/fisiologia , Prognóstico , Amplitude de Movimento Articular/fisiologia , Medição de Risco , Índice de Gravidade de Doença , Estenose Espinal/diagnóstico , Suporte de Carga/fisiologia
11.
Surg Today ; 49(2): 124-129, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30178212

RESUMO

PURPOSE: We examined the outcome of modified-maze procedures reflecting a single-center strategy in the treatment of atrial fibrillation (AF) associated with atrial septal defect (ASD) in adults. METHODS: A retrospective chart review was performed for 29 patients who underwent surgical ASD closure and 2 types of maze procedures (full and simplified maze procedures) for AF. The outcome related to the each procedure was examined. A Cox proportional hazards analysis was performed to assess the independent predictors of AF and atrial tachycardia (AT) recurrence. RESULTS: The rates of freedom from AF and AT recurrence at 1 and 4 years were 86.6% and 72.2% in the full maze group and 78.5% and 62.8% in the simplified maze group, respectively (p = 0.70). The only risk factor for recurrence was the age at the time of surgery. A receiver operating characteristic curve analysis gave an optimum cut-off value of 58 years of age for predicting recurrence within 2 years (58.4% for ≥ 58 years versus 5.9% for < 58 years, p = 0.003). CONCLUSIONS: Simplification of the maze procedure was not associated with AF or AT recurrence. The age at the time of surgery might be a clinical predictor of success or failure in adult patients.


Assuntos
Fibrilação Atrial/etiologia , Fibrilação Atrial/cirurgia , Procedimentos Cirúrgicos Cardíacos/métodos , Comunicação Interatrial/complicações , Comunicação Interatrial/cirurgia , Adulto , Fatores Etários , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos de Riscos Proporcionais , Curva ROC , Ablação por Radiofrequência , Recidiva , Estudos Retrospectivos , Fatores de Risco , Fatores de Tempo , Resultado do Tratamento
12.
J Nippon Med Sch ; 2019 Dec 27.
Artigo em Inglês | MEDLINE | ID: mdl-31902857

RESUMO

BACKGROUND: Spatial dispersion of the atrial activation is one cause of post-operative atrial fibrillation (PoAF) after cardiac surgery. This study aimed to evaluate whether temporal dispersion of the atrial activation also causes PoAF after surgery in the clinical setting. METHODS: Nineteen patients were enrolled to evaluate their postoperative atrial activation from atrial pacing wires on the right atrium by 24h Holter electrocardiography for 5 days after cardiac surgery. No patients had taken any antiarrhythmic drugs including beta-blockers. The cycle length of 15 continuous atrial beats was measured at 4 time points: (i) more than 12 hours before the PoAF as a control, (ii) just before the PoAF onset, (iii) during PoAF, and (iv) just before the termination of PoAF. The inhomogeneity of the atrial activation was quantified by the variation coefficient of the cycle length of 15 atrial beats during each phase. RESULTS: The median inhomogeneity index of the atrial activation (first quartile, third quartile) was 0.102 (0.046, 0.136) in the control, 0.943 (0.582, 1.610) just before the PoAF onset (vs. control; p=0.009), 0.966 (0.631, 1.117) during PoAF, and 0.471 (0.138, 0.645) just before the termination of PoAF, respectively. CONCLUSIONS: Dispersion of the atrial activation significantly increased just before the PoAF onset. Temporal dispersion of the atrial activation is one of the precursory variations of PoAF.

13.
Kyobu Geka ; 71(10): 794-799, 2018 09.
Artigo em Japonês | MEDLINE | ID: mdl-30310029

RESUMO

Fundamental procedure of arrhythmia surgery is to bock conduction of macro-reentry or focal activation. Traditional "cut and sew" technique is effective to make a conduction block without any special devices although it is time consuming and there is some bleeding risk. Surgical ablation devices are easily able to make a conduction block during surgery. It could undergo the minimally invasive cardiovascular surgery (MICS) -maze procedure through the right mini thoracotomy. It is most important to make complete conduction block because incomplete ablation causes residual conduction, resulting in recurrence of atrial fibrillation or atrial tachycardia. Moreover, the left atrial clip is new surgical treatment for atrial fibrillation. This device could avoid thrombus formation and make a conduction block arising from the left atrial appendage.


Assuntos
Arritmias Cardíacas/cirurgia , Ablação por Cateter , Sistema de Condução Cardíaco/cirurgia , Fibrilação Atrial/etiologia , Fibrilação Atrial/cirurgia , Ablação por Cateter/efeitos adversos , Ablação por Cateter/instrumentação , Ablação por Cateter/métodos , Átrios do Coração , Humanos , Complicações Pós-Operatórias/etiologia , Recidiva , Instrumentos Cirúrgicos , Taquicardia Supraventricular/etiologia , Taquicardia Supraventricular/cirurgia , Resultado do Tratamento
14.
J Acoust Soc Am ; 144(1): 53, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30075681

RESUMO

Recently, a perturbation approach was adopted for the non-collinear mixing of plate waves in an isotropic elastic plate with quadratic nonlinearity by Ishii, Biwa, and Adachi [J. Sound Vib. 419, 390-404 (2018)] and a resonance condition was derived theoretically, namely, that a significant scattered plate wave is generated when its frequency and wavevector coincide with the sum/difference of those of its primary waves. However, that analysis assumed monochromatic plane waves that interacted everywhere in the plate. To apply the non-collinear mixing of plate waves to nondestructive evaluation of plate-like structures, the influence of the spatial and temporal finiteness of the primary waves on the generation of the scattered wave must be elucidated. To that end, the present study conducts three-dimensional dynamic finite-element analyses on the mixing of lowest-order antisymmetric Rayleigh-Lamb waves that have finite beam widths and time durations. The generation of scattered lowest-order symmetric Rayleigh-Lamb and shear horizontal waves with sum frequencies is discussed for various beam widths, intersection angles, and primary frequencies. The resonance condition derived originally for monochromatic plane waves in the aforementioned study is found to be valid even when the wave interaction is allowed only within limited space and time.

15.
Circ J ; 82(6): 1481-1486, 2018 05 25.
Artigo em Inglês | MEDLINE | ID: mdl-29445060

RESUMO

Prevention of sudden cardiac death (SCD) has become an important issue in today's cardiovascular field, together with various developments in secondary prevention of basic cardiac diseases. The importance of the implantable cardioverter defibrillator (ICD) is now widely accepted because it has exhibited significant improvement in patients' prognoses in ischemic and non-ischemic cardiovascular diseases. However, there is an unignorable gap between the ICD indication in the guidelines and real-world high-risk patients for SCD, especially in the acute recovery phase of cardiac injury. Although various studies have demonstrated a clinical benefit of defibrillation devices, the studies of immediate ICD use in the acute recovery phase have failed to exhibit a benefit in patients from the point of the view of a decrease in total deaths. To bridge this gap, the wearable cardioverter defibrillator (WCD) provides a safer observation period in the acute phase and eliminates inappropriate overuse of ICD in the subacute phase. Here, we discuss the usefulness of the WCD and current understanding of its indications based on various clinical data. In conclusion, WCD is a feasible bridge to therapy and/or safe observation for patients at high risk of SCD, especially in the acute recovery phase of cardiac diseases.


Assuntos
Morte Súbita Cardíaca/prevenção & controle , Desfibriladores/normas , Dispositivos Eletrônicos Vestíveis , Doenças Cardiovasculares/terapia , Desfibriladores/tendências , Humanos , Japão
16.
Semin Thorac Cardiovasc Surg ; 30(3): 271-278, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29410135

RESUMO

The purpose of this study was to determine the 22-year experience of the relationship between preoperative left atrial diameter (LAD) and atrial fibrillation (AF) recurrence after AF surgery. Between November 1993 and April 2015, 244 patients underwent AF surgery concomitant with mitral valve surgery, and were completely followed up in our institute. The full-maze procedure was performed in 231 patients and pulmonary vein isolation in 13. Three quartiles divided the list of sorted LAD data into 4 groups: group Q1: LAD = 40.5 ± 4.3 (n = 55), group Q2: LAD = 47.9 ± 2.0 (n = 61), group Q3: LAD = 54.2 ± 1.6 (n = 66), and group Q4: LAD = 64.2 ± 5.6 (n = 62). The AF cure rates for 22 years were verified between the groups. Although the AF cure rate of the full-maze procedure was 94%, 80%, 63%, and 51% at 1, 5, 10, and 20 years after AF surgery, respectively, it was 100% at 5 and 10 years after the pulmonary vein isolation (P = 0.088). Although there were no significant differences in the AF cure rate between groups Q1-Q3, the AF cure rate was significantly lower in group Q4 than the other groups (P < 0.001). A multivariate Cox proportional hazard model revealed that the preoperative LAD and cardiothoracic ratio were significant risk factors of AF recurrence (hazard ratio 1.063 per 1-mm increase, P = 0.003, and hazard ratio 1.064 per 1% increase, P = 0.043, respectively). AF surgery was effective for 22 years after surgery for AF concomitant with mitral valve disease. A preoperative LAD of ≥58.0 mm and the cardiothoracic ratio were risk factors of AF recurrence after AF surgery.


Assuntos
Técnicas de Ablação/efeitos adversos , Fibrilação Atrial/cirurgia , Átrios do Coração/cirurgia , Doenças das Valvas Cardíacas/cirurgia , Valva Mitral/cirurgia , Veias Pulmonares/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Fibrilação Atrial/complicações , Fibrilação Atrial/diagnóstico por imagem , Fibrilação Atrial/fisiopatologia , Feminino , Átrios do Coração/diagnóstico por imagem , Átrios do Coração/fisiopatologia , Doenças das Valvas Cardíacas/complicações , Doenças das Valvas Cardíacas/diagnóstico por imagem , Doenças das Valvas Cardíacas/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Valva Mitral/diagnóstico por imagem , Valva Mitral/fisiopatologia , Veias Pulmonares/diagnóstico por imagem , Veias Pulmonares/fisiopatologia , Recidiva , Estudos Retrospectivos , Fatores de Risco , Fatores de Tempo , Resultado do Tratamento
17.
ACS Omega ; 3(11): 15598-15605, 2018 Nov 30.
Artigo em Inglês | MEDLINE | ID: mdl-31458216

RESUMO

9,10-Anthraquinone and 9,10-phenanthrenequinone (PhQ) were grafted onto two kinds of single-walled carbon nanotube (SWCNT) samples having different mean tube diameters by diazo-coupling reactions. The structural details of PhQ-grafted SWCNT (PhQ/SWCNT) samples were analyzed by X-ray diffraction and Raman measurements. It was discussed that a few-nanometer-thick layer of polymerized PhQs covers the outside of SWCNT bundles. The obtained PhQ/SWCNT works very well as lithium-ion battery and sodium-ion battery electrodes, not only at room temperature but also at 0 °C. It should be noted that the cycle performance of the PhQ/SWCNT electrode is much better than that of PhQ encapsulated in SWCNT (PhQ@SWCNT). We also calculated molecular base reaction energies by density functional theory calculations to gain a qualitative insight into the observed discharge potentials of the PhQ/SWCNT electrode.

18.
Knee ; 24(6): 1408-1413, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28970118

RESUMO

BACKGROUND: It is known that a lateral wedge insole (LWI) decreases medial loading stress in the knee. Medial meniscus pathology, such as a degenerative tear or a root tear, leading to malfunction and medial meniscus extrusion (MME), is a critical condition that leads to severe osteoarthritis (OA). However, the effect of LWI on MME is still unknown. The objective of this study was to investigate the effect of LWI use on MME in knee OA using ultrasonography. METHODS: Thirty-one knees from 18 patients with knee OA diagnosed radiographically were allocated to the OA group (mean age, 73.6years; sex M:F, 2:16). Twenty-two knees from 11 volunteers without knee OA were also enrolled as an age-matched control group. MME was evaluated using ultrasonography with the patients in three positions: supine, standing without LWI, and standing with LWI. RESULTS: In both groups, the mean values of the MME increased significantly when patients were in the standing position compared to the supine position. In the OA group, MME significantly decreased with LWI use. There was no significant difference in MME between use and non-use of an LWI in the control group. CONCLUSIONS: The LWI could significantly decrease MME in patients with knee OA.


Assuntos
Órtoses do Pé , Osteoartrite do Joelho/diagnóstico por imagem , Osteoartrite do Joelho/terapia , Índice de Gravidade de Doença , Idoso , Estudos de Casos e Controles , Feminino , Humanos , Masculino , Postura , Ultrassonografia
19.
World Neurosurg ; 108: 427-435, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28893695

RESUMO

OBJECTIVE: Although indirect bypass surgery is an effective treatment option for patients with ischemic-onset moyamoya disease (MMD), the time point after surgery at which the patient's hemodynamic status starts to improve and the time point at which the improvement reaches a maximum have not been known. The objective of the present study is to evaluate the hemodynamic status time course after indirect bypass surgery for MMD, using dynamic susceptibility contrast-magnetic resonance imaging (DSC-MRI). METHODS: We retrospectively analyzed the cases of 25 patients with MMD (37 sides; mean age, 14.7 years; range, 3-36 years) who underwent indirect bypass surgery and repeated DSC-MRI measurement within 6 months after the operation. The difference in the mean transit time (MTT) between the target regions and the control region (cerebellum) was termed the MTT delay, and we measured the MTT delay's chronologic changes after surgery. RESULTS: The postoperative MTT delay was 1.81 ± 1.16 seconds within 1 week after surgery, 1.57 ± 1.01 at weeks 1-2, 1.55 ± 0.68 at weeks 2-4, 1.32 ± 0.68 at months 1-2, 0.95 ± 0.32 at months 2-3, and 0.77 ± 0.33 at months 3-6. Compared with the preoperative value (2.11 ± 0.98 seconds), the MTT delay decreased significantly from 2 to 4 weeks after surgery (P < 0.05). CONCLUSIONS: The amelioration of cerebral hemodynamics by indirect bypass surgery began soon after surgery and gradually reached a maximum at 3 months after surgery. DSC-MRI detected small changes in hemodynamic improvement, which are suspected to be caused by the initiation of angiogenesis and arteriogenesis in the early postoperative period.


Assuntos
Circulação Cerebrovascular , Doença de Moyamoya/fisiopatologia , Doença de Moyamoya/cirurgia , Adolescente , Adulto , Fatores Etários , Criança , Pré-Escolar , Meios de Contraste , Feminino , Humanos , Imagem por Ressonância Magnética , Masculino , Doença de Moyamoya/diagnóstico por imagem , Estudos Retrospectivos , Resultado do Tratamento , Adulto Jovem
20.
Nanotechnology ; 28(35): 355401, 2017 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-28660854

RESUMO

We have performed Li and Na ion charge-discharge experiments of 9,10-phenanthrene quinone (PhQ) molecules encapsulated in single-walled carbon nanotubes (SWCNTs) with mean tube diameters of 1.5 and 2.5 nm at room temperature and also at low temperatures. The Na ion reversible capacity of PhQ encapsulated in the larger diameter SWCNTs, measured at a low temperature of 0 °C, remained as high as that measured at room temperature (RT), while the capacity of PhQ in the smaller diameter SWCNTs at 0 °C was about a half of that at RT. The diameter dependence of the capacity should be attributed to the difference in the interactions between the encapsulated PhQ molecules and the host SWCNTs, which was revealed by Raman peak profile analysis. Charge-transfer reaction from metallic tubes to PhQ molecules encapsulated in the smaller diameter SWCNTs was detected by Raman measurements. The electrostatic interaction between charged SWCNTs and PhQ molecules, induced by the charge-transfer reaction, would partly contribute to the stabilization of PhQ molecules in the smaller diameter SWCNTs, while only van der Waals interaction stabilizes PhQ molecules in the larger diameter SWCNTs. The difference in stability was confirmed by thermogravimetric, x-ray photoelectron spectroscopy, and Raman measurements. Charge-discharge curves of PhQ encapsulated in SWCNTs were also discussed based on the stability difference.

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