Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 13 de 13
Filtrar
1.
Herz ; 2022 Jan 10.
Artigo em Inglês | MEDLINE | ID: mdl-35006290

RESUMO

BACKGROUND: We investigated the feasibility of evaluating coronary arteries with a contrast-enhanced (CE) self-navigated sparse isotropic 3D whole heart T1-weighted magnetic resonance imaging (MRI) study sequence. METHODS: A total of 22 consecutive patients underwent coronary angiography and/or cardiac computed tomography (CT) including cardiac MRI. The image quality was evaluated on a 3-point Likert scale. Inter-reader variability for image quality was analyzed with Cohen's kappa for the main coronary segments (left circumflex [LCX], left anterior descending [LAD], right coronary artery [RCA]) and the left main trunk (LMT). RESULTS: Inter-reader agreement for image quality of the coronary tree ranged from substantial to perfect, with a Cohen's kappa of 0.722 (RCAmid) to 1 (LCXprox). The LMT had the best image quality. Image quality of the proximal vessel segments differed significantly from the mid- and distal segments (RCAprox vs. RCAdist, p < 0.05). The LCX segments showed no significant difference in image quality along the vessel length (LCXprox vs. LCXdist, p = n.s.). The mean acquisition time for the study sequence was 553 s (±46 s). CONCLUSION: Coronary imaging with a sparse 3D whole-heart sequence is feasible in a reasonable amount of time producing good-quality imaging. Image quality was poorer in distal coronary segments and along the entire course of the LCX.

2.
Antimicrob Resist Infect Control ; 10(1): 170, 2021 12 20.
Artigo em Inglês | MEDLINE | ID: mdl-34930466

RESUMO

A survey of hospitals on three continents was performed to assess their infection control preparedness and measures, and their infection rate in hospital health care workers during the COVID-19 pandemic. All surveyed hospitals used similar PPE but differences in preparedness, PPE shortages, and infection rates were reported.


Assuntos
COVID-19/epidemiologia , Controle de Infecções/métodos , Recursos Humanos em Hospital/estatística & dados numéricos , Hospitais , Humanos , Internacionalidade , Pandemias , Equipamento de Proteção Individual , Inquéritos e Questionários
3.
Anticancer Res ; 41(10): 5053-5058, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34593454

RESUMO

BACKGROUND/AIM: Investigation of the influence of different ultra-low dose computed tomography (ULDCT) protocols on the detection of solid and subsolid nodules in a phantom study. PATIENTS AND METHODS: A chest phantom with pulmonary nodules was scanned with different CT protocols ranging from ultra-low dose settings with spectral shaping to a standard low dose lung cancer screening protocol. Image analysis was performed with different reconstruction algorithms and dedicated computer aided detection (CAD), which was compared to manual readout. RESULTS: The highest sensitivity rates (83%) were achieved for the 90 mAs and 120 mAs protocols when reconstructed with ADMIRE 3 or 5 and manual readout. The only statistically significant difference was found for subsolid nodules with preference of manual readout compared to CAD (p<0.05). Dose levels for the mAs settings ranged from 0.029 to 0.2 mSv. CONCLUSION: Reliable detectability rates for solid nodules were achieved; CAD software did not prove reliable for subsolid nodules.


Assuntos
Detecção Precoce de Câncer/métodos , Processamento de Imagem Assistida por Computador/métodos , Neoplasias Pulmonares/diagnóstico , Nódulos Pulmonares Múltiplos/diagnóstico , Imagens de Fantasmas , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Tomografia Computadorizada por Raios X/métodos , Algoritmos , Seguimentos , Humanos , Neoplasias Pulmonares/diagnóstico por imagem , Nódulos Pulmonares Múltiplos/diagnóstico por imagem , Prognóstico , Estudos Prospectivos , Doses de Radiação
4.
Surg Radiol Anat ; 43(12): 2009-2023, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34599355

RESUMO

PURPOSE: Defining normal anthropometric ranges of proximal femur and femoral head for each age group in children/adolescents is a necessity when differentiating normal anatomical variants from pathological deformities. Aim of this study is to define a set of normal anthropometric parameters based on 3D-CT measurements in normal asymptomatic children/adolescents and analyse the variations arising depending on age, side, and/or gender. METHODS: Morphology of the proximal femur was retrospectively assessed in 170 hips (85 children, < 15 years). Measurements included covered femoral head volume (CFHV), femoral head diameter (FHD), femoral head extrusion index (FHEI), coronal alpha angle (CAA), lateral centre-edge angle (LCEA), anterior (AOS) and posterior head-neck offset (POS) and femoral neck-shaft angle (FNSA). Correlation analyses as well as inter- and intra-rater reliability were performed. RESULTS: CFHV, LCEA, FHD and AOS/POS increased with age and FHEI, CAA, and FNSA decreased with age. None of the measurements correlated with the side. AOS showed a poor correlation with gender. Rapid growth phases were observed at the age of 1, 7 and 11. The inter- and intra-rater reliability was high (range ICC 0.8-0.99 Cronbach alpha 0.86-0.99). CONCLUSION: This data delivers a description of growth phases as well as gender and age-correlated reference values of the proximal femoral morphology that could be used by paediatricians and orthopaedic/paediatric surgeons to early diagnose proximal femur deformities and provide guidance in the planning of possible operations.

5.
Eur Radiol ; 31(4): 2126-2131, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33021703

RESUMO

Faced with the COVID-19 pandemic, many countries both in Europe and across the world implemented strict stay-at-home orders. These measures helped to slow the spread of the coronavirus but also led to increased mental and physical health issues for the domestically confined population, including an increase in the occurrence of intimate partner violence (IPV) in many countries. IPV is defined as behavior that inflicts physical, psychological, or sexual harm within an intimate relationship. We believe that as radiologists, we can make a difference by being cognizant of this condition, raising an alert when appropriate and treating suspected victims with care and empathy. The aim of this Special Report is to raise awareness of IPV among radiologists and to suggest strategies by which to identify and support IPV victims. KEY POINTS: • The COVID-19 pandemic led to a marked increase in the number of intimate partner violence (IPV) cases, potentially leading to increased emergency department visits and radiological examinations. • Most IPV-related fractures affect the face, fingers, and upper trunk, and may easily be misinterpreted as routine trauma. • Radiologists should carefully review the medical history of suspicious cases, discuss the suspicion with the referring physician, and proactively engage in a private conversation with the patient, pointing to actionable resources for IPV victims.


Assuntos
COVID-19 , Violência por Parceiro Íntimo , Europa (Continente) , Humanos , Pandemias/prevenção & controle , Radiologistas , SARS-CoV-2
6.
Magn Reson Imaging ; 75: 116-123, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32987123

RESUMO

Development of a deterministic algorithm for automated detection of the Arterial Input Function (AIF) in DCE-MRI of colorectal cancer. Using a filter pipeline to determine the AIF region of interest. Comparison to algorithms from literature with mean squared error and quantitative perfusion parameter Ktrans. The AIF found by our algorithm has a lower mean squared error (0.0022 ±â€¯0.0021) in reference to the manual annotation than comparable algorithms. The error of Ktrans (21.52 ±â€¯17.2%) is lower than that of other algorithms. Our algorithm generates reproducible results and thus supports a robust and comparable perfusion analysis.


Assuntos
Algoritmos , Artérias/diagnóstico por imagem , Artérias/fisiopatologia , Circulação Sanguínea , Neoplasias Colorretais/diagnóstico por imagem , Neoplasias Colorretais/fisiopatologia , Imageamento por Ressonância Magnética , Automação , Meios de Contraste , Humanos , Processamento de Imagem Assistida por Computador , Reprodutibilidade dos Testes
7.
PLoS One ; 15(11): e0241590, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33180805

RESUMO

OBJECTIVES: The aim of this study was to establish quantitative CT (qCT) parameters for pathophysiological understanding and clinical use in patients with acute respiratory distress syndrome (ARDS). The most promising parameter is introduced. MATERIALS AND METHODS: 28 intubated patients with ARDS obtained a conventional CT scan in end-expiratory breathhold within the first 48 hours after admission to intensive care unit (ICU). Following manual segmentation, 137 volume- and lung weight-associated qCT parameters were correlated with 71 clinical parameters such as blood gases, applied ventilation pressures, pulse contour cardiac output measurements and established status and prognosis scores (SOFA, SAPS II). RESULTS: Of all examined qCT parameters, excess lung weight (ELW), i.e. the difference between a patient's current lung weight and the virtual lung weight of a healthy person at the same height, displayed the most significant results. ELW correlated significantly with the amount of inflated lung tissue [%] (p<0.0001; r = -0.66) and was closely associated with the amount of extravascular lung water (EVLW) (p<0.0001; r = 0.72). More substantially than the oxygenation index (PaO2/FiO2) or any other clinical parameter it correlated with the patients' mean SOFA- (p<0.0001, r = 0.69) and SAPS II-Score (p = 0.0005, r = 0.62). Patients who did not survive intensive care treatment displayed higher values of ELW in the initial CT scans. CONCLUSIONS: ELW could serve as a non-invasive method to quantify the amount of pulmonary oedema. It might serve as an early radiological marker of severity in patients with ARDS.


Assuntos
Pulmão/diagnóstico por imagem , Edema Pulmonar/diagnóstico , Síndrome do Desconforto Respiratório/diagnóstico , Tomografia Computadorizada por Raios X , Adulto , Idoso , Estudos de Viabilidade , Feminino , Mortalidade Hospitalar , Humanos , Unidades de Terapia Intensiva/estatística & dados numéricos , Pulmão/fisiopatologia , Medidas de Volume Pulmonar/métodos , Masculino , Pessoa de Meia-Idade , Edema Pulmonar/etiologia , Edema Pulmonar/mortalidade , Edema Pulmonar/fisiopatologia , Síndrome do Desconforto Respiratório/complicações , Síndrome do Desconforto Respiratório/mortalidade , Síndrome do Desconforto Respiratório/fisiopatologia , Testes de Função Respiratória , Índice de Gravidade de Doença
8.
Surg Oncol ; 34: 109-112, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32891314

RESUMO

BACKGROUND: Local recurrence (LR) of retroperitoneal soft tissue sarcoma (RPS) is a common and life-threatening event. The evaluation of the exact anatomical patterns of local recurrence might help to improve local treatment in RPS. METHODS: Of our local database we extracted ten patients with LR of RPS with axial MRI and/or CT datasets of the primary tumor (PT) and the LR. Using the Osirix DICOM viewer Version v.3.9.4 64-bit (Pixmeo, Geneva, Switzerland) we performed a three-step fusion algorithm consisting of: a) 3-point co-registration of the axial datasets depicting the PT and the LR using three abdominal landmarks b) re-orientation of the datasets and c) image fusion. We evaluated the feasibility of this technique with regard to categorizing the localization of LR as within or distant from the PT. RESULTS: Fusion imaging was feasible in seven out of ten patients. In the other three patients anatomical shifting of organs after surgery led to a relevant mismatch of anatomical landmarks and impeded interpretation of the fused images. In five of seven patients with successful fusion imaging, local recurrences were located within the anatomical borders of the primary tumor, in two out of seven patients local recurrences were distant to the primary. CONCLUSIONS: Fusion imaging of primary tumors and local recurrences is feasible in most patients with RPS. Most local recurrences occurred within the anatomical localization of the primary tumor. For further investigations validation of the technique in larger patient cohorts is required.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/métodos , Recidiva Local de Neoplasia/patologia , Neoplasias Retroperitoneais/patologia , Sarcoma/patologia , Tomografia Computadorizada por Raios X/métodos , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/diagnóstico por imagem , Recidiva Local de Neoplasia/cirurgia , Projetos Piloto , Prognóstico , Estudos Prospectivos , Neoplasias Retroperitoneais/diagnóstico por imagem , Neoplasias Retroperitoneais/cirurgia , Sarcoma/diagnóstico por imagem , Sarcoma/cirurgia
9.
Eur Radiol ; 30(12): 6933-6936, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32607631

RESUMO

KEY POINTS: • The COVID-19 crisis resulted in a variety of physical and mental health issues beyond the viral infection itself, as indicated by an increase in domestic violence.• Radiologists should be aware of typical intimate partner violence (IPV) injury patterns, actively ask potential IPV victims about the cause of injury, and be familiar with support systems for IPV victims of their institutions.• Emergency and radiology departments should review their protocols for identifying and supporting IPV victims, and train their staff to work together to implement these measures during and beyond the COVID-19 crisis.


Assuntos
Infecções por Coronavirus/diagnóstico , Serviço Hospitalar de Emergência , Violência por Parceiro Íntimo/psicologia , Pandemias , Pneumonia Viral/diagnóstico , Radiologistas , Betacoronavirus , COVID-19 , Infecções por Coronavirus/psicologia , Feminino , Humanos , Masculino , Pneumonia Viral/psicologia , SARS-CoV-2
11.
J Clin Med ; 9(3)2020 Mar 03.
Artigo em Inglês | MEDLINE | ID: mdl-32138259

RESUMO

Background: Machine-learning-based computed-tomography-derived fractional flow reserve (CT-FFRML) obtains a hemodynamic index in coronary arteries. We examined whether it could reduce the number of invasive coronary angiographies (ICA) showing no obstructive lesions. We further compared CT-FFRML-derived measurements to clinical and CT-derived scores. Methods: We retrospectively selected 88 patients (63 ± 11years, 74% male) with chronic coronary syndrome (CCS) who underwent clinically indicated coronary computed tomography angiography (cCTA) and ICA. cCTA image data were processed with an on-site prototype CT-FFRML software. Results: CT-FFRML revealed an index of >0.80 in coronary vessels of 48 (55%) patients. This finding was corroborated in 45 (94%) patients by ICA, yet three (6%) received revascularization. In patients with an index ≤ 0.80, three (8%) of 40 were identified as false positive. A total of 48 (55%) patients could have been retained from ICA. CT-FFRML (AUC = 0.96, p ≤ 0.0001) demonstrated a higher diagnostic accuracy compared to the pretest probability or CT-derived scores and showed an excellent sensitivity (93%), specificity (94%), positive predictive value (PPV; 93%) and negative predictive value (NPV; 94%). Conclusion: CT-FFRML could be beneficial for clinical practice, as it may identify patients with CAD without hemodynamical significant stenosis, and may thus reduce the rate of ICA without necessity for coronary intervention.

12.
J Clin Med ; 9(3)2020 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-32155743

RESUMO

BACKGROUND: The aim is to compare the machine learning-based coronary-computed tomography fractional flow reserve (CT-FFRML) and coronary-computed tomographic morphological plaque characteristics with the resting full-cycle ratio (RFRTM) as a novel invasive resting pressure-wire index for detecting hemodynamically significant coronary artery stenosis. METHODS: In our single center study, patients with coronary artery disease (CAD) who had a clinically indicated coronary computed tomography angiography (cCTA) and subsequent invasive coronary angiography (ICA) with pressure wire-measurement were included. On-site prototype CT-FFRML software and on-site CT-plaque software were used to calculate the hemodynamic relevance of coronary stenosis. RESULTS: We enrolled 33 patients (70% male, mean age 68 ± 12 years). On a per-lesion basis, the area under the receiver operating characteristic curve (AUC) of CT-FFRML (0.90) was higher than the AUCs of the morphological plaque characteristics length/minimal luminal diameter4 (LL/MLD4; 0.80), minimal luminal diameter (MLD; 0.77), remodeling index (RI; 0.76), degree of luminal diameter stenosis (0.75), and minimal luminal area (MLA; 0.75). CONCLUSION: CT-FFRML and morphological plaque characteristics show a significant correlation to detected hemodynamically significant coronary stenosis. Whole CT-FFRML had the best discriminatory power, using RFRTM as the reference standard.

13.
Anthropol Anz ; 77(1): 75-82, 2020 Feb 13.
Artigo em Inglês | MEDLINE | ID: mdl-31939989

RESUMO

In the course of a scientific cooperation between the German Mummy Project at the Reiss-Engelhorn-Museen, Mannheim (Germany) and the Musée National d'Histoire et d'Art Luxembourg (Luxembourg), an ancient Egyptian mummy head was analyzed using a multidisciplinary approach including radiocarbon dating, ultra-high resolution computed tomography, physical anthropology, forensic medicine and Egyptology. Dated to the Roman Period, the mummy head belonged to an upper-class woman between 25 and 35 years of age. Computed tomography revealed a lethal blunt force trauma affecting the dorsal parts of the parietal bones, below the intact overlaying soft tissue. Moreover, ancient medical treatment was evidenced through localized shaving of the hair on the affected area, which indicates that efforts have been made to keep the woman alive. This astonishing example of homicide demonstrates the enormous scientific benefit brought by the multidisciplinary investigation of mummified bodies and body parts, and sheds light on life, death and medical care of a woman from Roman Period Egypt.


Assuntos
Traumatismos Craniocerebrais , Múmias , Ferimentos não Penetrantes , Adulto , Antigo Egito , Feminino , Cabeça , História Antiga , Humanos
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...