Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Seizure ; 56: 115-120, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29475094

RESUMO

PURPOSE: BECTS (benign childhood epilepsy with centrotemporal spikes) is associated with characteristic EEG findings. This study examines the influence of anti-convulsive treatment on the EEG. METHODS: In a randomized controlled trial including 43 children with BECTS, EEGs were performed prior to treatment with either Sulthiame or Levetiracetam as well as three times under treatment. Using the spike-wave-index, the degree of EEG pathology was quantified. The EEG before and after initiation of treatment was analyzed. Both treatment arms were compared and the EEG of the children that were to develop recurrent seizures was compared with those that were successfully treated. RESULTS: Regardless of the treatment agent, the spike-wave-index was reduced significantly under treatment. There were no differences between the two treatment groups. In an additional analysis, the EEG characteristics of the children with recurrent seizures differed statistically significant from those that did not have any further seizures. CONCLUSION: Both Sulthiame and Levetiracetam influence the EEG of children with BECTS. Persistent EEG pathologies are associated with treatment failures.


Assuntos
Anticonvulsivantes/uso terapêutico , Ondas Encefálicas/efeitos dos fármacos , Epilepsia Rolândica/tratamento farmacológico , Piracetam/análogos & derivados , Tiazinas/uso terapêutico , Criança , Método Duplo-Cego , Eletroencefalografia , Feminino , Alemanha , Humanos , Levetiracetam , Masculino , Piracetam/uso terapêutico , Estudos Retrospectivos , Estatísticas não Paramétricas , Resultado do Tratamento
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA