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1.
Braz J Biol ; 84: e256486, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35293544

RESUMO

This study explores the antioxidant activity, phytochemical screening, total phenolic and flavonoids contents in the extracts of four locally available weeds plants namely Convolvulus arvensis, Chenopodium murale, Avena fatua and Phalaris minor with different solvents. The antioxidant activities of these extracts were determined via various in-vitro methods such as total antioxidant activity (TAA), reducing power (RP), DPPH (2,2-Diphenyl-1-Picrylhydrazyl) free radical scavenging and hydrogen peroxide scavenging assays. Phytochemical screening was performed both qualitatively as well as quantitatively. Total phenolic content (TPC) and total flavonoid content (TFC) were determined through Folin- Ciocalteu reagent and aluminium chloride methods respectively. Methanol-chloroform solvent showed the presence of a high amount of TPC in milligram of gallic acid equivalent per gram of dry weight (mg of GAE/g of DW) in the extracts of all weeds. Their descending sequence was Avena fatua (74.09) ˃ Phalaris minor (65.66) ˃ Chenopodium murale (64.04) ˃ Convolvulus arvensis (61.905), while, chloroform solvent found to be best solvent for the extraction of TFC. Methanol-chloroform solvent was also found to be best solvent for TAA (Total antioxidant activity assay) which showed values in milligram of ascorbic acid equivalent per gram of dry weight (mg of AAE /g of DW), for DPPH scavenging activity, reducing power (antioxidant activity) and hydrogen peroxide scavenging activity. Phytochemical screening indicated the presence of polyphenols, flavonoids, tannins, saponins, alkaloids and glycosides in these weeds.


Assuntos
Antioxidantes , Flavonoides , Antioxidantes/química , Flavonoides/química , Sequestradores de Radicais Livres/química , Compostos Fitoquímicos , Picratos , Triticum
2.
Eur Rev Med Pharmacol Sci ; 25(22): 7058-7065, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34859870

RESUMO

OBJECTIVE: Diabetes mellitus is a chronic metabolic disease which has an adverse impact on the quality of patient's life, so patients often need to receive treatment for a long time. Selection of medications with high therapeutics effects and low cost is very important for patients to take medicine for a longer period of time. Sitagliptin is a drug which is widely used in clinics and can effectively control blood glucose level. This article explores the pharmacoeconomic value of Sitagliptin in the treatment of diabetes mellitus. PATIENTS AND METHODS: A total of 100 patients with diabetes mellitus treated were recruited in this study. The patients were randomly divided into 4 groups with 25 cases in each group. Patients in group A were treated with pioglitazone, group B with Sitagliptin, group C with metformin and group D with glimepiride. The cost of the drugs, the treatment results and adverse effects were compared. RESULTS: Compared with group A, C and D, the cost-effectiveness ratio of group B was low (p<0.05), and the therapeutic effect was high (p<0.05). In addition, the incidence of adverse reactions in group B was lower than that in group A, C and D (p<0.05). There was no significant difference in the levels of FPG, 2hPG and HbAlc in patients among the four groups before treatment (p>0.05). After treatment, the levels of FPG, 2hPG and HbAlc in group B were significantly lower than those in groups A, C and D (p<0.05). Finally, there was no significant difference in waist circumference and BMI among the four groups before treatment (p>0.05). After treatment, the waist circumference and BMI in group B were lower than those in groups A, C and D (p<0.05). CONCLUSIONS: The application of Sitagliptin in the treatment of diabetic patients can effectively enhance the therapeutic effect. The cost effectiveness is satisfactory, and the blood glucose level can be maintained at a stable state.


Assuntos
Diabetes Mellitus/tratamento farmacológico , Hipoglicemiantes/uso terapêutico , Fosfato de Sitagliptina/uso terapêutico , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise Custo-Benefício , Diabetes Mellitus/economia , Farmacoeconomia , Feminino , Humanos , Hipoglicemiantes/efeitos adversos , Hipoglicemiantes/economia , Masculino , Metformina/economia , Metformina/uso terapêutico , Pessoa de Meia-Idade , Pioglitazona/economia , Pioglitazona/uso terapêutico , Fosfato de Sitagliptina/efeitos adversos , Fosfato de Sitagliptina/economia , Compostos de Sulfonilureia/economia , Compostos de Sulfonilureia/uso terapêutico
6.
Neth J Med ; 75(7): 307, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28956790
7.
Int J Cosmet Sci ; 37(2): 253-8, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25402429

RESUMO

BACKGROUND: Vitis vinifera 'muscat hamburg' (Vitaceae) is a blue-black grape variety commonly found in Pakistan. It has been consumed and used in traditional medicine for centuries. Compared to other grapes, M. hamburg records one of the greatest amount of polyphenols and displays potent antioxidant activities, which make it a great candidate for its exploitation in the development of stable cream emulsions destined to improve the skin appearance. OBJECTIVE: Evaluate the effects of stable water-in-oil (W/O) emulsion containing 2% M. hamburg grape seed extract ('formulation') on human cheek skin in comparison with the placebo ('base'). METHODS: An occlusive patch test, containing either the formulation or the base, was topically tested for 8 weeks during a winter period in young adult and healthy Pakistani male volunteers. The subjects were instructed to use twice a day the base and the formulation on their right and left cheek skin, respectively. Non-invasive measurements on these skin areas were carried out every week to assess any effects produced on melanin, elasticity and sebum. Skin compatibility assay (Burchard test) was used to report any potential skin reactivity. ANOVA, paired sample t-test and LSD test were applied to determine the statistical data significance. RESULTS: Significant differences (P ≤ 0.05) were found between the placebo and the formulation in terms of their respective skin effects elicited on melanin, elasticity and sebum content. Nevertheless, placebo and formulation exerted similar effects on skin erythema and moisture contents. Importantly, no skin hypersensitivity cases were reported during the whole course of the study. CONCLUSION: The developed grape-based cream could be efficiently and safely applied to improve a number of skin conditions (e.g. hyper-pigmentation, premature ageing, acne).


Assuntos
Extratos Vegetais/farmacologia , Sementes/química , Pele/efeitos dos fármacos , Vitis/química , Humanos , Óleos , Método Simples-Cego , Vitis/embriologia , Água
8.
J Helminthol ; 89(2): 232-7, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24429044

RESUMO

Serological diagnosis of cystic echinococcosis (CE) is usually made by detecting specific antibodies in serum samples. However, collection of blood samples is difficult and may be hazardous and unsafe. Thus, it is important to assess alternative simple methods of sampling body fluids that give similar results. Saliva and urine have been suggested as possible alternatives to detect specific antibodies for the diagnosis of various diseases. To the best of our knowledge, there has been no previously published study regarding the detection of CE-specific immunoglobulin (Ig) G subclass antibodies (IgG1-4) in urine. Therefore, the present study was designed to assess the value of hydatid-specific antibodies of IgG, IgM, IgE and IgG subclass in urine and serum samples for the diagnosis of CE. Serum and urine samples of 41 surgically confirmed patients of CE, 40 patients with other diseases and 16 healthy subjects were included in the study. CE-specific total IgG, IgE and IgG4 in sera and total IgG, IgG4 and IgG1 in the urine of CE patients were the most important specific antibodies for the diagnosis of CE. However, total IgG usually persists for an extended period and has a very high cross-reactivity. The diagnostic sensitivity of hydatid-specific IgM in serum and urine samples was very low and therefore cannot be used as a diagnostic marker. There was no significant difference between IgG1 and IgG4 in serum and urine and both showed the best correlation for the diagnosis of CE. These considerations suggest that detection of antibodies in urine could provide a new approach in the diagnosis of CE.


Assuntos
Anticorpos Anti-Helmínticos/sangue , Anticorpos Anti-Helmínticos/urina , Equinococose/diagnóstico , Echinococcus/isolamento & purificação , Testes Sorológicos/métodos , Adulto , Animais , Equinococose/sangue , Equinococose/parasitologia , Equinococose/urina , Echinococcus/imunologia , Feminino , Humanos , Índia , Masculino , Pessoa de Meia-Idade
9.
Pharmazie ; 67(1): 54-8, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22393831

RESUMO

This study was aimed to formulate and evaluate anti-aging effects of a topical cream (w/o emulsion) containig extract of Fennel (Foeniculum vulgare) versus its base. Formulation containing 4% concentrated extract of Foeniculum vulgare was developed by entrapping in the inner aqueous phase of w/o emulsion and base contained no extract. Both the base and formulation were stored under different storage conditions to predict their stability. The formulation and base were evaluated for effect on skin moisture and transepidermal water loss (TEWL). The base showed insignificant while the formulation showed significant effects on skin moisture and TEWL. The parameter volume and surface evaluation of living skin (SELS) parameters SEr, SEsc, SEsm, SEw were also evaluated and showed a significant (p < or = 0.05) decline. The texture parameter energy showed a significant increase proving that the formulation possesses potential anti-aging effects.


Assuntos
Foeniculum/química , Envelhecimento da Pele/efeitos dos fármacos , Adulto , Antioxidantes/química , Antioxidantes/farmacologia , Compostos de Bifenilo/química , Química Farmacêutica , Cor , Condutividade Elétrica , Emulsões , Humanos , Umidade , Concentração de Íons de Hidrogênio , Masculino , Pessoa de Meia-Idade , Pomadas , Testes do Emplastro , Picratos/química , Extratos Vegetais/efeitos adversos , Extratos Vegetais/química , Extratos Vegetais/farmacologia , Pele/química , Solubilidade , Propriedades de Superfície , Temperatura , Perda Insensível de Água
11.
Transpl Infect Dis ; 13(3): 324-8, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21631655

RESUMO

Human metapneumovirus (hMPV) is an emerging human pulmonary pathogen that is genetically related to respiratory syncytial virus. It has been increasingly associated with respiratory illnesses over the last few decades. Immunocompromised patients are particularly susceptible with resultant morbidity and mortality. We describe our experience with 9 immunocompromised patients diagnosed with pneumonia secondary to hMPV, 2 of whom were successfully treated with aerosolized and oral ribavirin along with intravenous immunoglobulin (IVIG). We suggest that hMPV should be considered in the differential diagnosis of immunocompromised patients with acute respiratory illness. Ribavirin (oral and aerosolized) with IVIG is potentially an effective treatment option for those with severe disease.


Assuntos
Transplante de Células-Tronco Hematopoéticas/efeitos adversos , Transplante de Pulmão/efeitos adversos , Metapneumovirus , Infecções por Paramyxoviridae , Infecções Respiratórias , Adulto , Idoso , Antivirais/uso terapêutico , Feminino , Humanos , Hospedeiro Imunocomprometido , Imunoglobulinas Intravenosas/uso terapêutico , Masculino , Pessoa de Meia-Idade , Infecções por Paramyxoviridae/tratamento farmacológico , Infecções por Paramyxoviridae/fisiopatologia , Infecções por Paramyxoviridae/virologia , Infecções Respiratórias/tratamento farmacológico , Infecções Respiratórias/fisiopatologia , Infecções Respiratórias/virologia , Ribavirina/uso terapêutico , Resultado do Tratamento
12.
Neurology ; 75(2): 152-9, 2010 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-20625168

RESUMO

BACKGROUND: Anticholinergic properties of certain medications often go unrecognized, and are frequently used by the elderly population. Few studies have yet defined the long-term impact of these medications on the incidence of cognitive impairment. METHODS: We report a 6-year longitudinal, observational study, evaluating 1,652 community-dwelling African American subjects over the age of 70 years who were enrolled in the Indianapolis-Ibadan Dementia Project between 2001 and 2007 and who had normal cognitive function at baseline. The exposure group included those who reported the baseline use of possible or definite anticholinergics as determined by the Anticholinergic Cognitive Burden scale. Our main outcome measure was the incidence of cognitive impairment, defined as either dementia or cognitive impairment not dementia, or poor performance on a dementia screening instrument during the follow-up period. RESULTS: At baseline, 53% of the population used a possible anticholinergic, and 11% used a definite anticholinergic. After adjusting for age, gender, educational level, and baseline cognitive performance, the number of definite anticholinergics was associated with an increased risk of cognitive impairment (odds ratio [OR] 1.46, 95% confidence interval [CI] 1.07-1.99; p = 0.02), whereas the number of possible anticholinergics at baseline did not increase the risk (OR 0.96, 95% CI 0.85-1.09; p = 0.55). The risk of cognitive impairment among definite anticholinergic users was increased if they were not carriers of the APOE epsilon4 allele (OR 1.77, 95% CI 1.03-3.05; p = 0.04). CONCLUSIONS: Limiting the clinical use of definite anticholinergics may reduce the incidence of cognitive impairment among African Americans.


Assuntos
Antagonistas Colinérgicos/uso terapêutico , Transtornos Cognitivos/epidemiologia , /genética , Idoso , Idoso de 80 Anos ou mais , Apolipoproteínas E/genética , Distribuição de Qui-Quadrado , Transtornos Cognitivos/diagnóstico , Transtornos Cognitivos/genética , Feminino , Humanos , Incidência , Estudos Longitudinais , Masculino , Testes Neuropsicológicos , Razão de Chances , Risco , Fatores de Risco
13.
Indian J Gastroenterol ; 25(1): 37, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16567895

RESUMO

We report a 37-year-old man with portal cavernoma who developed pericardial effusion two weeks following sclerotherapy for esophageal varices. It responded to conservative management.


Assuntos
Varizes Esofágicas e Gástricas/terapia , Derrame Pericárdico/etiologia , Escleroterapia/efeitos adversos , Adulto , Humanos , Masculino , Derrame Pericárdico/terapia
14.
Eur J Drug Metab Pharmacokinet ; 29(2): 125-32, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15230341

RESUMO

This randomized, six-treatment, six-period, six sequence, single dose, crossover pharmacokinetic study assessed the effect of different types of food on the bioavailability of 500-mg cefaclor extended release tablet in 23 healthy male volunteers. A single dose of cefaclor extended release 500-mg tablet was administered at six occasions: after overnight fasting, after two vegetarian (high-fat and low-fat), two non-vegetarian (high-fat and low-fat) and rice diets. Serial blood samples were collected up to 12 h after dose. Serum cefaclor concentrations were determined by a validated HPLC method. An almost equivalent increase in both Cmax and AUC was observed with both high-fat non-vegetarian and low-fat vegetarian breakfasts. However, when MIC90 values, a pharmacodynamic end-point were compared, the low-fat vegetarian diet fared better than the high-fat non-vegetarian diet. The results obtained favor low-fat vegetarian diet (breakfast) to be taken with cefaclor extended release tablet to achieve maximum benefit in terms of clinical efficacy.


Assuntos
Cefaclor/administração & dosagem , Cefaclor/farmacocinética , Cefalosporinas/administração & dosagem , Cefalosporinas/farmacocinética , Interações Alimento-Droga , Adulto , Área Sob a Curva , Disponibilidade Biológica , Cromatografia Líquida de Alta Pressão , Estudos Cross-Over , Preparações de Ação Retardada , Dieta com Restrição de Gorduras , Dieta Vegetariana , Gorduras na Dieta/farmacologia , Humanos , Modelos Lineares , Masculino , Oryza , Triticum
15.
J Pak Med Assoc ; 52(9): 417-22, 2002 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-12532578

RESUMO

OBJECTIVE: To study the risk factors, etiology and management of ischemic stroke in young adults in a South Asian population. METHODS: Retrospective study conducted at a large tertiary hospital in Karachi. One hundred and eighteen patients between fifteen and forty-five years admitted over a five year period with a diagnosis of ischemic infarct constituted the study population. The study variables included the full clinical spectrum, spanning historical, laboratory, radiological and outcome parameters. RESULTS: Forty-three percent of patients were hypertensive and 30% were diabetic. The combination of diabetes and hypertension was found in 19.5% of patients, intra-cranial and carotid artherosclerosis in 22% and embolism in 11% of the cases. The in-hospital mortality was 11%. The outcome was excellent in 27%, good in 50% and poor in 23% of patients. CONCLUSION: The risk factors for artherosclerosis and the contribution of intra and extra-cranial artherosclerosis were found to be much higher than those from the Western Hemisphere.


Assuntos
Estenose das Carótidas/complicações , Acidente Vascular Cerebral , Adolescente , Adulto , Arteriosclerose/complicações , Isquemia Encefálica/epidemiologia , Isquemia Encefálica/etiologia , Estenose das Carótidas/diagnóstico por imagem , Ecocardiografia , Feminino , Mortalidade Hospitalar , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Paquistão/epidemiologia , Estudos Retrospectivos , Fatores de Risco , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/epidemiologia , Acidente Vascular Cerebral/etiologia , Acidente Vascular Cerebral/terapia
16.
Am J Med ; 111(4): 280-4, 2001 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-11566458

RESUMO

BACKGROUND: Therapeutic endoscopy has provided a new means of treating bleeding peptic ulcers. Additional medical therapy may enhance the therapeutic benefit. Hemostasis is highly pH dependent and is severely impaired at low pH. Proton pump inhibitors, by achieving a significantly higher inhibition of gastric acidity, may improve the therapeutic outcomes after endoscopic treatment of ulcers. PATIENT AND METHODS: We enrolled 166 patients with hemorrhage from duodenal, gastric, or stomal ulcers and signs of recent hemorrhage, as confirmed by endoscopy. Twenty-six patients had ulcers with an arterial spurt, 41 patients had active ooze, 37 had a visible vessel, and 62 patients had an adherent clot. All patients received endoscopic injection sclerotherapy using 1:10,000 adrenaline and 1% polidocanol and were randomly assigned to receive omeprazole (40 mg orally) every 12 hours for 5 days or an identical-looking placebo. The outcome measures used were recurrent bleeding, surgery, blood transfusion, and hospital stay. RESULTS: Six (7%) of 82 patients in the omeprazole group had recurrent bleeding, as compared with 18 (21%) in the placebo group (P = 0.02). Two patients in the omeprazole group and 7 patients in the placebo group needed surgery to control their bleeding (P = 0.17). One patient in the omeprazole group and 2 patients in the placebo group died (P = 0.98). Twenty-nine patients (35%) in the omeprazole group and 61 patients (73%) in the placebo group received blood transfusions (P <0.001). The average hospital stay was 4.6 +/- 1.1 days in the omeprazole group and 6.0 +/- 0.7 days in the placebo group (P <0.001). CONCLUSION: The addition of oral omeprazole to combination injection sclerotherapy decreases the rate of recurrent bleeding, reduces the need for surgery and transfusion, and shortens the hospital stay for patients with stigmata of recent hemorrhage.


Assuntos
Antiulcerosos/uso terapêutico , Úlcera Duodenal/complicações , Omeprazol/uso terapêutico , Úlcera Péptica Hemorrágica/tratamento farmacológico , Escleroterapia/métodos , Úlcera Gástrica/complicações , Distribuição de Qui-Quadrado , Quimioterapia Combinada , Endoscopia Gastrointestinal , Feminino , Hemostase Endoscópica , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva , Resultado do Tratamento
18.
J Pak Med Assoc ; 49(4): 97-9, 1999 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-10540539

RESUMO

BACKGROUND: The present study focuses on the role of carotid doppler ultrasonography (CDUS) in the diagnosis and management of carotid stenosis in young stroke patients. METHODS: The findings of carotid doppler in 45 ischemic stroke patients between 15-45 years of age were reviewed retrospectively. The variables of interest for this study included risk factors for atherosclerotic disease, primary abnormality detected on carotid doppler ultrasonography (ulceration vs. stenosis), degree of stenosis and the type of plaque (soft vs. calcified). RESULTS: The prevalence of hypertension and diabetes was 50% and 35% respectively. The rate of carotid stenosis in the study population was found to be 31%. The degree of stenosis was mild in 35% and moderate in 21%. High-grade stenosis was found in 21% of patients. The plaque was soft in the majority of cases (43%). CONCLUSION: The proportion of carotid stenosis in young stroke patients was relatively high compared with previous studies. This may be due to an increase in the risk factors for atherosclerotic disease in developing countries.


Assuntos
Artérias Carótidas/diagnóstico por imagem , Estenose das Carótidas/diagnóstico por imagem , Acidente Vascular Cerebral/diagnóstico por imagem , Ultrassonografia Doppler , Adolescente , Adulto , Arteriosclerose/prevenção & controle , Estenose das Carótidas/complicações , Estenose das Carótidas/epidemiologia , Feminino , Humanos , Masculino , Paquistão/epidemiologia , Estudos Retrospectivos , Fatores de Risco , Acidente Vascular Cerebral/epidemiologia , Acidente Vascular Cerebral/etiologia
19.
J Pak Med Assoc ; 49(3): 66-8, 1999 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-10531784

RESUMO

BACKGROUND: This study investigates the role of CT and MR imaging in the diagnosis and management of young stroke patients. METHODS: CT scan findings of 108 patients and MR findings of 30 patients between 15-45 years of age were reviewed retrospectively. The variables included the territory of infarct on CT and MR imaging, the cortical distribution and size of infarct. RESULTS: About 80% of the patients had infarcts of the carotid territory and 20% the vertebro-basilar distribution. More than half of the infarcts were cortical (56%). The yield of MR imaging was much higher for deeper structures such as basal ganglia, thalamus and brainstem. In half the cases, the infarct size was more than 3 cm. CONCLUSION: The ratio of carotid to vertebro-basilar infarcts was similar to that reported previously. A large proportion of the carotid territory infarcts were cortical. Deeper infarcts were better imaged with MR scan. There was a high proportion of large infarcts.


Assuntos
Acidente Vascular Cerebral/diagnóstico , Adolescente , Adulto , Encéfalo/diagnóstico por imagem , Infarto Cerebral/diagnóstico , Humanos , Imageamento por Ressonância Magnética , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Insuficiência Vertebrobasilar/diagnóstico
20.
World J Surg ; 23(11): 1191-4, 1999 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-10501884

RESUMO

The prevalence, symptomatology, and outcome of Ascaris-induced liver abscess was studied prospectively in Kashmir, India, which is an endemic area of ascariasis, from December 1987 to December 1997. Of 510 patients with liver abscess admitted during this period, 74 had biliary ascariasis as the cause (14.51%). Of these 74 patients, 11 had intact ascaridae (live or dead) within the abscess. Six patients had a single abscess, and five had multiple abscesses. Seven patients had associated worms in the bile ducts. Ultrasonography was the main diagnostic procedure used. Ten patients were diagnosed based on clinical and ultrasound findings, and one was diagnosed during laparotomy. Most of the patients were young (age range 3-40 years) with a mean age of 17.20 years. Seven were females, and four were males. Ten patients underwent surgery; nine recovered completely, and one died postoperatively due to septicemia. Another patient died as well: a young child who presented late, was in refractory septic shock following suppurative cholangitis and liver abscess, and could not be taken for surgery. The mortality thus was 9.9%. Liver abscess following invasion of intrahepatic biliary radicles by ascaridae through the ampulla is an unusual complication of an otherwise common disease in Kashmir Valley, affecting children and young adults. The outcome depends on early diagnosis and surgical drainage of the abscess with extraction of worms from the ducts.


Assuntos
Ascaríase/epidemiologia , Abscesso Hepático/parasitologia , Adolescente , Adulto , Fatores Etários , Ampola Hepatopancreática/parasitologia , Ascaríase/fisiopatologia , Ascaríase/cirurgia , Doenças dos Ductos Biliares/epidemiologia , Doenças dos Ductos Biliares/parasitologia , Doenças dos Ductos Biliares/fisiopatologia , Doenças dos Ductos Biliares/cirurgia , Ductos Biliares Intra-Hepáticos/parasitologia , Causas de Morte , Criança , Pré-Escolar , Colangite/parasitologia , Doenças Endêmicas , Feminino , Humanos , Índia/epidemiologia , Abscesso Hepático/epidemiologia , Abscesso Hepático/fisiopatologia , Abscesso Hepático/cirurgia , Masculino , Prevalência , Estudos Prospectivos , Fatores Sexuais , Choque Séptico/parasitologia , Taxa de Sobrevida , Resultado do Tratamento
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