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1.
Artigo em Inglês | MEDLINE | ID: mdl-33916791

RESUMO

To identify gender- and age-related associations between adult dental checkups and unmet dental care needs, we analyzed data of 14,000 participants, from the Seventh Korea National Health and Nutrition Examination Survey (2016-2018). Data were collected via self-report questionnaires and interviews. The complex sample chi-square test and multiple logistic regression analysis indicated that 31.7% of participants had unmet dental care needs. Within the previous 12 months, 56.5% did not undertake dental checkups, and 29.3% did not use a dental service. Odds ratios (ORs) of the unmet dental needs were 8.87 (confidence interval (CI) = 7.80-10.09, p < 0.001) for those who did not use dental services and 1.28 (CI = 1.13-1.44, p < 0.001) for those who did not have dental checkups. Significant age-dependent associations between those not receiving dental checkups and the rate of unmet dental care included men and women aged 50-59 years and women ≥70 years. However, unmet dental care needs for men aged ≥70 years not undergoing dental checkups were not statistically significant (p = 0.311). Overall, it was found that the use of dental service and dental checkups were the influencing factors for unmet dental care needs.

2.
Healthcare (Basel) ; 9(3)2021 Mar 23.
Artigo em Inglês | MEDLINE | ID: mdl-33806836

RESUMO

Physically disabled persons can have sleep problems, which affects their mental health more than those in non-disabled people. However, there are few studies on the relationship between sleep duration and mental health targeting physically disabled people in South Korea, and existing studies on the disabled have mostly used data collected from convenience rather than nationally representative samples, limiting the generalization of the results. This study used data from the second wave of the Panel Survey of Employment for the Disabled (PSED, 2016-2018, 1st-3rd year). Participants included 1851 physically disabled individuals. The Chi-square test and generalized estimating equation (GEE) were used and the Akaike information criterion (AIC) value and the AIC log Bayes factor approximation were used to select sleep trajectories. This is the first study to elucidate multiple sleep trajectories in physically disabled people in Korea, and the relationship between sleep duration trajectories and self-rated depressive symptoms. People with physical disabilities who sleep more than 9 h have the highest risk of depression and need more intensive management as a priority intervention.

3.
Nutrients ; 13(3)2021 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-33806628

RESUMO

Cone of Pinus densiflora (CP), or Korean red pinecone, is a cluster of Pinus densiflora fruit. CP has also been verified in several studies to have anti-oxidation, anti-fungal, anti-bacterial, and anti-melanogenic effects. However, anti-inflammatory effects have not yet been confirmed in the inflammatory responses of pinecones to allergic contact dermatitis. The purpose of this study is to prove the anti-inflammatory effect of CP on allergic contact dermatitis (ACD) in vitro and in vivo. CP inhibited the expression of TSLP, TARC, MCP-1, TNF-α, and IL-6 in TNF-α/IFN-γ-stimulated HaCaT cells and MCP-1, GM-CSF, TNF-α, IL-6, and IL-8 in PMACI (phorbol-12-myristate-13-acetate plus A23187)-stimulated HMC-1 cells. CP inhibited the phosphorylation of mitogen-activated protein kinase (MAPKs), as well as the translocation of NF-κB on TNF-α/IFN-γ stimulated in HaCaT cells. In vivo, CP decreased major symptoms of ACD, levels of IL-6 in skin lesion, thickening of the epidermis and dermis, infiltration of eosinophils and mast cells, and the infiltration of CD4+ T cells and CD8+ T cells. This result suggests that CP represents a potential alternative medicine to ACD for diseases such as chronic skin inflammation.

4.
Lang Speech Hear Serv Sch ; : 1-18, 2021 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-33848195

RESUMO

Purpose This study reports on data from a survey of speech-language pathologists' (SLPs) language assessment practices for elementary school-age children. The objective was to investigate the regularity with which SLPs use different types of assessments (described across data types, task types, environmental contexts, and dynamic features). This study also investigated factors that influence assessment practice, the main sources from which SLPs obtain information on language assessment and the main challenges reported by SLPs in relation to language assessment. Method A web-based survey was used to collect information from 407 Australian SLPs regarding the types of assessments they use. Factors that influenced the regularity with which different types of assessments were used were investigated using regression analysis. Results Most SLPs regularly used assessments that are norm-referenced, decontextualized, and conducted in a clinical context and less regularly used other types of assessments. Service agency, Australian state, and SLPs' years of experience were found to influence the regularity with which some types of assessments were used. Informal discussions with colleagues were the most frequently identified source of information on assessment practice. Main challenges related to limited time, lack of assessment materials, and lack of confidence in assessing children from culturally and linguistically diverse backgrounds. Conclusions SLPs could improve current language assessment practice for elementary school-age children through more regular use of some types of assessments. Actions to facilitate evidence-based assessment practice should consider the contextual differences that exist between service agencies and states and address challenges that SLPs experience in relation to language assessment. Supplemental Material https://doi.org/10.23641/asha.14378948.

5.
Orthod Craniofac Res ; 24 Suppl 1: 31-38, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33652500

RESUMO

INTRODUCTION: The purpose of this study was to evaluate the long-term position of erupted third molars after maxillary total arch distalization using modified C-palatal plates (MCPPs) in adolescents and to identify factors associated with these positions. SETTING AND SAMPLE POPULATION: Sixty-two third molars (male: 20, female: 42) in Class II patients treated with MCPPs and thirty-nine teeth for the Control group (male: 22, female: 17). MATERIALS AND METHODS: Samples were analyzed using panoramic radiographs taken initially (T0), after treatment (T1) and after >3 years retention (T2). Third molars were classified as downward (Group A, N = 31; males: 12, females: 19) and upward (Group B, N = 31; males: 8, females: 23) based on their vertical position after treatment. Analysis of variance and multiple logistic regression analysis were performed. RESULTS: The vertical position of the third molars of Group A, Group B, and the Control showed a 2.2, 3.5 and 2.7 mm downward movement at T2. However, there was no difference in the amount of third molar eruption among the groups. Regarding factors affecting the vertical distance of the third molar, Age, C8-OP, ∠8-OP and D7-T at the initial affected vertical position of the third molars after molar distalization (P < .05). CONCLUSIONS: Group A and B showed no difference in the third molar eruption during retention after total arch distalization. This study suggests that it might be unnecessary to extract the developing third molar before molar distalization in Class II adolescents.


Assuntos
Má Oclusão de Angle Classe II , Dente Serotino , Adolescente , Cefalometria , Feminino , Humanos , Masculino , Maxila/diagnóstico por imagem , Dente Molar/diagnóstico por imagem , Dente Serotino/diagnóstico por imagem , Dente Serotino/cirurgia , Técnicas de Movimentação Dentária
6.
Sci Rep ; 11(1): 6061, 2021 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-33723333

RESUMO

Herein, using data from the Korean Longitudinal Study of Aging (2006-2018), we evaluated denture use and chewing ability to determine the status of oral health in middle-aged adults who exercised regularly; further, we investigated the relationship of oral health with all-cause mortality. From the basic survey conducted in 2006, we interviewed 10,254 participants who were followed up until death. The participants were grouped based on regular exercise into REG (n = 3921) and non-REG (n = 6290) groups. The mortality rate was higher in the non-REG group than in the REG group (35.8% versus 26.9%; p < 0.001). The mortality rate was higher in denture users (versus non-denture users), non-drinkers (versus alcohol drinkers), and those on medical aid (versus national health insurance). The mortality rate was higher in participants with poor masticatory ability, lower education level, and poor subjective health perception (p < 0.001). Denture use and masticatory discomfort were not significant risk factors for mortality in the non-REG group (p > 0.05). In conclusion, masticatory discomfort was a risk factor for increased mortality in middle-aged Korean adults who exercised regularly, at least once a week. Thus, assessment of masticatory ability could be a useful indicator of life expectancy in middle-aged adults.

7.
Sensors (Basel) ; 21(4)2021 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-33672454

RESUMO

Green tide, which is a serious water pollution problem, is caused by the complex relationships of various factors, such as flow rate, several water quality indicators, and weather. Because the existing methods are not suitable for identifying these relationships and making accurate predictions, a new system and algorithm is required to predict the green tide phenomenon and also minimize the related damage before the green tide occurs. For this purpose, we consider a new network model using smart sensor-based federated learning which is able to use distributed observation data with geologically separated local models. Moreover, we design an optimal scheduler which is beneficial to use real-time big data arrivals to make the overall network system efficient. The proposed scheduling algorithm is effective in terms of (1) data usage and (2) the performance of green tide occurrence prediction models. The advantages of the proposed algorithm is verified via data-intensive experiments with real water quality big-data.

8.
J Alzheimers Dis ; 80(1): 197-207, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33523000

RESUMO

BACKGROUND: While atypical antipsychotic medications are widely used for treating depressive disorders, their long-term effects on the risk of subsequent dementia have not been studied adequately. OBJECTIVE: To investigate whether the risk of dementia differs according to the use of atypical antipsychotic drugs, and compare the effects of antipsychotic agents on dementia risk in individuals with late-life depressive disorders. METHODS: A nationwide population-based retrospective cohort study was conducted using data from the National Health Insurance Service-Senior Cohort of South Korea. Atypical antipsychotic dosages were standardized using a defined daily dose, and the cumulative dosage was calculated. Participants were observed from January 2008 to December 2015. Cox proportional hazard regression analysis was used to estimate the hazard ratios. RESULTS: The cohort included 43,788 elderly adults with depressive disorders: 9,901 participants (22.6%) were diagnosed with dementia. Findings showed that atypical antipsychotics were prescribed to 1,967 participants (4.5%). Compared with non-users, users of atypical antipsychotics experienced a significantly higher risk for dementia with an adjusted hazard ratio (aHR) of 1.541 (95% confidence interval [CI], 1.415-1.678). A cumulative dose-response relationship was observed (test for trend, p < 0.0001). Among atypical antipsychotics, risperidone displayed the highest risk for dementia (aHR 1.767, [95% CI, 1.555-2.009]). CONCLUSION: In this study of elderly individuals with depressive disorders, atypical antipsychotic use was associated with a significantly higher risk of subsequent dementia. Healthcare professionals should be aware of this potential long-term risk. A limitation that should be mentioned is that we could not exclude patients with bipolar depression.

9.
J Control Release ; 332: 109-126, 2021 Apr 10.
Artigo em Inglês | MEDLINE | ID: mdl-33571549

RESUMO

Cancer immunotherapy has revolutionized the standard of care for solid tumors in multiple disease sites. In light of this, immune checkpoint blockade, directly interfering with various immunosuppressive mechanisms in tumor sites, has been actively studied. Inhibitors of cytotoxic T-lymphocyte-associated protein 4 (CTLA 4) and programmed cell death 1 receptor (PD-1) / programmed cell death receptor ligand 1 (PD-L1) could successfully increase survival rate in patients with advanced cancers including melanoma and non-small cell lung cancer, leading to increased survival and different patterns of response including durable response and pseudo-progression. Despite continued development of the immune checkpoint blockades, however, fairly low overall response rate (ORR) levels have been reported for patients with various types of cancer. Fewer than 13% of patients with cancer were reported to respond to immune checkpoint blockades and some patients were diagnosed with severe immune-related adverse events (irAEs). The tumor microenvironment, controlled via various components and mediators, is regarded as the primary cause responsible for failure of immune checkpoint blockades in clinical investigations. In fact, there has been a clinical report that epidermal growth factor receptor (EGFR) inhibition in tumor microenvironment enhanced ORR of PD-1 inhibitors for 29.7% in EGFR-mutated non-small-cell lung carcinoma (NSCLC) patients. Therefore, to enhance the effectiveness and reduce adverse effects of immune checkpoint blockades, the majority of studies have focused on targeting and suppressing the immunosuppressive characteristics of the tumor microenvironment. Herein, we review the components and mediators of tumor microenvironment responsible for failure of immune checkpoint blockades and introduce the recent approaches of tumor microenvironment component-targeted nanomedicine delivery capable of enhancing the efficacy of immune checkpoint blockades. Understanding the active targeting candidates of tumor microenvironment components and the associated treatment strategies could offer insights into the development of combination therapeutics boosting immune checkpoint blockades for clinical applications.

10.
PLoS One ; 16(1): e0245446, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33444365

RESUMO

The resveratrol-producing rice (Oryza sativa L.) inbred lines, Iksan 515 (I.515) and Iksan 526 (I.526), developed by the expression of the groundnut (Arachis hypogaea) resveratrol synthase 3 (AhRS3) gene in the japonica rice cultivar Dongjin, accumulated both resveratrol and its glucoside, piceid, in seeds. Here, we investigated the effect of the AhRS3 transgene on the expression of endogenous piceid biosynthesis genes (UGTs) in the developing seeds of the resveratrol-producing rice inbred lines. Ultra-performance liquid chromatography (UPLC) analysis revealed that I.526 accumulates significantly higher resveratrol and piceid in seeds than those in I.515 seeds and, in I.526 seeds, the biosynthesis of resveratrol and piceid reached peak levels at 41 days after heading (DAH) and 20 DAH, respectively. Furthermore, RNA-seq analysis showed that the expression patterns of UGT genes differed significantly between the 20 DAH seeds of I.526 and those of Dongjin. Quantitative real-time PCR (RT-qPCR) analyses confirmed the data from RNA-seq analysis in seeds of Dongjin, I.515 and I.526, respectively, at 9 DAH, and in seeds of Dongjin and I.526, respectively, at 20 DAH. A total of 245 UGTs, classified into 31 UGT families, showed differential expression between Dongjin and I.526 seeds at 20 DAH. Of these, 43 UGTs showed more than 2-fold higher expression in I.526 seeds than in Dongjin seeds. In addition, the expression of resveratrol biosynthesis genes (PAL, C4H and 4CL) was also differentially expressed between Dongjin and I.526 developing seeds. Collectively, these data suggest that AhRS3 altered the expression pattern of UGT genes, and PAL, C4H and 4CL in developing rice seeds.

11.
Nat Commun ; 12(1): 97, 2021 01 04.
Artigo em Inglês | MEDLINE | ID: mdl-33397978

RESUMO

Globally, soybean is a major protein and oil crop. Enhancing our understanding of the soybean domestication and improvement process helps boost genomics-assisted breeding efforts. Here we present a genome-wide variation map of 10.6 million single-nucleotide polymorphisms and 1.4 million indels for 781 soybean individuals which includes 418 domesticated (Glycine max), 345 wild (Glycine soja), and 18 natural hybrid (G. max/G. soja) accessions. We describe the enhanced detection of 183 domestication-selective sweeps and the patterns of putative deleterious mutations during domestication and improvement. This predominantly selfing species shows 7.1% reduction of overall deleterious mutations in domesticated soybean relative to wild soybean and a further 1.4% reduction from landrace to improved accessions. The detected domestication-selective sweeps also show reduced levels of deleterious alleles. Importantly, genotype imputation with this resource increases the mapping resolution of genome-wide association studies for seed protein and oil traits in a soybean diversity panel.


Assuntos
Domesticação , Mutação/genética , Soja/genética , Cromossomos de Plantas/genética , Bases de Dados Genéticas , Variação Genética , Genética Populacional , Genoma de Planta , Estudo de Associação Genômica Ampla , Haplótipos/genética , Filogenia , Seleção Genética
12.
J Affect Disord ; 281: 174-182, 2021 02 15.
Artigo em Inglês | MEDLINE | ID: mdl-33321383

RESUMO

OBJECTIVE: This study estimates the association between fall experiences during the last two years and risk of depression. METHODS: Data from 9,355 subjects of the Korean Longitudinal Study of Ageing from 2006 to 2016 were included with baseline at 2006. To analyze the association between fall experiences during the last two years and depression, a generalized estimating equation (GEE) model and chi-square tests were used. RESULTS: At baseline 2006, the odds ratio (OR) of depressive symptoms in those with fall experiences was 1.36 times higher (p < .0001) than those with non-fall experience. In those 64 years or younger and 65 years or older, the OR of depressive symptoms in fall experience was 1.45 times higher (p =0.003) and 1.34 times higher (p =0.000) than those with non-fall experience, respectively. In males and females, the OR of depressive symptoms in those with fall experience was 1.47 times higher (p 0.008) and 1.34 times higher (p =0.000) than those with non-fall experience, respectively. CONCLUSION: Fall experiences during the last two years are associated with depressive symptoms. Therefore, self-reported screening for fall experiences might aid in population-based prevention strategies for depressive symptoms.


Assuntos
Acidentes por Quedas , Depressão , Envelhecimento , Depressão/epidemiologia , Feminino , Humanos , Estudos Longitudinais , Masculino , República da Coreia/epidemiologia
13.
Artigo em Inglês | MEDLINE | ID: mdl-33332112

RESUMO

Optoelectronic applications using perovskites have emerged as one of the most promising platforms such as phototransistors, photovoltaics, and photodetectors. However, high-performance and reliable perovskite photonic devices are often hindered by the limited spectral ranges of the perovskite system along with the lack of appropriate processing technologies for the implementation of reliable device architectures. Here, we explore a hybrid phototransistor with a heterojunction of a Sn-Pb binary mixed halide perovskite (CsSn0.6Pb0.4I2.6Br0.4) light absorber and an amorphous-In-Ga-Zn-O (a-IGZO) charge carrying layer. By incorporating Sn-Pb binary components with an all-inorganic base, broadening of light-absorbing spectral ranges with enhanced stability has been achieved, indicating inevitable highly increased conductivity, which triggers a high off-current of the devices. Accordingly, the selectively ultraviolet (UV)-irradiated electrical deactivation (SUED) process is carried out to suppress the high off-current with a reliable device structure. Particularly, it is noted that the selective UV irradiation can facilitate oxidation and distortion of the chemical structure in specific perovskite regions, providing enhanced gate bias modulation of the phototransistor with an increased on/off-current ratio from ∼103 to ∼106. Finally, the SUED-processed phototransistor exhibits an improvement in the photosensitivity by more than 3 orders of magnitude up to 8.0 × 104 and detects in the spectral range from visible to near-infrared (NIR) light (∼860 nm) with good on/off switching behaviors.

14.
Arch Gerontol Geriatr ; 93: 104285, 2020 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-33232916

RESUMO

This study investigates the interaction between the neighborhood effect of cognitive function on self-rated health among middle aged and older adults. Data from the Korean Longitudinal Study on Aging (KLoSA) were analyzed. A total of 9,998 participants were selected for biennial follow-ups from 2006 to 2018 to estimate the probability of change in cognitive function according to individual, regional and dependent variables. A generalized estimating equation (GEE) model and chi-square test were used. The odds ratio (OR) of underestimation, when an individual's cognitive function is lower than his/her regional average of cognitive function, was 1.173 times higher (95 % Confidence Interval [CI]: 1.108-1.241, p-value: <.0001) compared to accurate, when an individual's cognitive function is equal to his/her regional average of cognitive function. The OR of individuals with low cognitive function in regions with low cognitive function levels had the highest probability of poor SRH (self-rated health) (OR: 3.525; 95 % CI: 3.182-3.905, p-value: <.0001) compared to individuals with high cognitive function in regions with high cognitive function levels. Findings speak of the importance of the neighborhood effect of cognitive function on self-rated health among Korean middle aged and older adults. Further research is needed to investigate the potential mediation of pleasurable mechanisms in the rapidly aging population of Korea.

15.
Arthroscopy ; 2020 Nov 12.
Artigo em Inglês | MEDLINE | ID: mdl-33188853

RESUMO

PURPOSE: To compare postoperative objective knee stability and clinical outcomes between double-bundle (DB) anterior cruciate ligament reconstruction (ACLR) and single-bundle (SB) ACLR combined with lateral extra-articular tenodesis (LET). METHODS: ACL-injured patients with grade 3 pivot-shift who underwent either DB ACLR (DB ACLR group) or SB ACLR with LET (SB ACLR+LET group) were enrolled. All patients who met inclusion and exclusion criteria were retrospectively evaluated for knee laxity (the anterior translation and pivot-shift grade), clinical outcomes using the International Knee Documentation Committee (IKDC) examination form, Kellgren-Lawrence grade, graft maturation score on second-look arthroscopy, and revision rates at the last follow-up. RESULTS: From an initial cohort of 171 consecutive patients over a 3-year period, 95 (56%) met inclusion and exclusion criteria. The SB ACLR+LET group (n = 47) showed significantly better results in pivot-shift grade at the last follow-up as compared with the DB ACLR group (n = 48) (P = .021). In the SB ACLR+LET group, 93.6% (44/47) were grade 0, whereas 72.9% (35/48) in the DB ACLR group were grade 0. The SB ACLR+LET group (grade A: 42, grade B: 4 and grade C: 1) showed significantly superior results in IKDC objective grade compared with the DB ACLR group (grade A: 32; grade B: 8; and grade C: 8) (P = .017). However, no statistically significant difference could be shown in anterior translation, subjective functional IKDC score, or revision rate between the 2 groups. The mean follow-up duration was 49.7 ± 5.7 months. CONCLUSIONS: SB ACLR + LET demonstrated fewer pivot-shifts (P = .021) and superior IKDC objective grades (P = .017) than a DB ACLR at a mean follow-up of almost 50 months. LEVEL OF EVIDENCE: Level III, retrospective comparative study.

16.
ACS Omega ; 5(43): 27749-27755, 2020 Nov 03.
Artigo em Inglês | MEDLINE | ID: mdl-33163757

RESUMO

As the light-emitting diode (LED) size gradually decreases, it is difficult to conventionally transfer an LED onto a donor substrate. In this paper, we propose a print transfer method that selectively transfers an LED onto a UV release tape, i.e., the donor substrate, via focused laser scanning with Lissajous patterns. We implemented an optical system based on focused laser scanning to perform selective transfer; this can adjust the scanning area immediately without changing the donor substrate size according to the LED size. Because the commercialized UV release tape is utilized as a donor substrate, the adhesion between the LED and donor substrate can be constantly maintained even after repeated experiments. In this study, several LEDs were transferred to a flexible printed circuit board-arranged in a circular and square shape to demonstrate a high degree of freedom of the system-and turned on.

17.
Health Promot Int ; 2020 Oct 16.
Artigo em Inglês | MEDLINE | ID: mdl-33063107

RESUMO

A few studies explored the relationships among leisure-time physical activity (LTPA), coping, and life satisfaction among individuals with physical disabilities. This study aims to investigate how LPTA contributes to coping and life satisfaction among Korean individuals with physical disabilities. Using a purposive sampling strategy, a total of 351 people with physical disabilities participated in this study. The results of this study find that participation in LTPA leads to the development of active coping strategies that contribute to increased life satisfaction. This study suggests that encouraging LTPA participation can be a critical task to healthcare providers working with individuals with physical disabilities.

18.
PeerJ ; 8: e10007, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33024639

RESUMO

We collected an undescribed laophontid copepod from a coarse sand habitat on the east coast of Korea and named it Quinquelaophonte enormis sp. nov. We compared the detailed morphological characteristics of the new species with those of congeneric species. Among them, the new species shows a superficial resemblance to the Californian species Quinquelaophonte longifurcata Lang, 1965. However, the two species are easily distinguishable by the setation of the syncoxa on the maxilliped and the fourth swimming leg. The new species has the variable setation on the second to fourth swimming legs. The variations appear among individuals or between the left and right rami of a pair of legs in a single specimen. Although complex chaetotaxical polymorphism occur in this new species, we used myCOI and Cytb to confirm that the new species is not a species complex. Also, partial sequences of 18S and 28S ribosomal RNA genes were used to analyze the position of the new species within the family Laophontidae. The new speciesis the fourteenth Quinquelaophonte species in the world and the second species in Korea.

19.
PLoS One ; 15(10): e0241360, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33119673

RESUMO

OBJECTIVE: The purpose of this study was to investigate the association between grip strength and hypertension in the Korean population aged 65 years or older. Furthermore, individual differences in BMI were taken into account to examine whether grip strength or a relative grip strength predicted hypertension better. METHODS: Data from the Korean Longitudinal Study of Ageing from 2006 to 2016 were assessed, and a total of 3,383 participants were analyzed in our study (Male: 1,527, Female: 1,856). Using the generalized estimating equation model, the association between grip strength and hypertension, assessed by the response to the question 'have you ever been diagnosed with hypertension from your doctor?', over the follow-up period was analyzed. The relative grip strength, calculated by dividing the mean grip strength by BMI, was also analyzed in association of hypertension. RESULTS: Both grip strength and relative grip strength were significantly associated with hypertension in our sample. However, the results were more significant in the total sample when relative grip strength was used. In terms of grip strength, as the High group as reference: Low (Odds Ratio (OR): 1.238, 95% Confidence Interval (CI): 1.096, 1.397), Middle Low (OR: 1.104, 95% CI: 0.990, 1.231), and Middle high (OR: 1.024, 95% CI: 0.934, 1.122). In the analysis using relative grip strength, as High group as reference: Low (OR: 1.393, 95% CI: 1.234, 1.573), Middle low (OR: 1.232, 95% CI: 1.104, 1.374), and Middle high (OR:1.104, 95% CI: 1.009, 1.209). Furthermore, the lower QIC measure in the model with relative grip strength (QIC: 25,251) compared with the one using grip strength (QIC: 25,266) indicated a better model fit in the former. CONCLUSIONS: The results of the current study strengthen the previous findings in regards to hand grip strength and health. Furthermore, the results of our study shines light on the necessity of considering individual differences in BMI, when using a physical measure as a study variable.

20.
Jpn J Nurs Sci ; : e12390, 2020 Oct 27.
Artigo em Inglês | MEDLINE | ID: mdl-33107213

RESUMO

AIM: The aim of this study was to verify the long-term effect between social activity, cognitive function and life satisfaction in Korean older adults after adjusting for gender, age, and education. In addition, we test the mediating impact of cognitive function on the relationship between social activity and life satisfaction. METHODS: This study used the data from Korean Longitudinal Study of Aging survey, which was conducted biennially from 2006 to 2016. Data of 4,164 adults aged 65 years and older (mean age = 73.0 years) were analyzed with multivariate latent growth modeling. RESULTS: Results indicate that increases in social activity were related to increases in cognitive function and life satisfaction. Increases in cognitive function were associated with increases in life satisfaction. Finally, social activity indirectly impacted life satisfaction through cognitive function. CONCLUSION: Results suggest that efforts to maintain social activity and cognitive function are needed to improve life satisfaction in older adults.

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