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1.
Cleft Palate Craniofac J ; : 1055665619874979, 2019 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-31522540

RESUMO

OBJECTIVE: To analyze congenital lateral maxillary growth for patients with bilateral cleft lip and palate (BCLP). DESIGN: A retrospective study. SETTING: Kanagawa Children's Medical Center. MATERIALS: Images from computed tomography (CT) of patients with BCLP and control patients that were previously used for treatment. MAIN OUTCOME MEASURES: The following landmarks were used: A, the posterior most point of the piriform aperture; B, the superior most point of the acoustic meatus; C, the point at which line A-B intersects the line drawn perpendicular from line A-B to the maxillary tuberosity; and D, the apical most point of the nasal bone. The following distances were then measured using these landmarks: (1) A-B distance; (2) A-C distance; (3) A-C/A-B; (4) the angle between lines A-B and A-D (∠BAD); and (5) B-D distance. RESULT: Mean A-B and A-C distances and A-C/A-B were significantly smaller in the BCLP group than in the control group (P < .01 each). Mean ∠BAD was significantly larger in the BCLP group than in the control group (P < .01). Mean B-D distance did not differ significantly between groups. CONCLUSIONS: Our results indicated that the lateral maxillary segments of patients with BCLP were more posterior than those of the control group, and segment length was shorter compared to the control group on 3D-CT analysis. The lateral maxillary segments of patients with BCLP were basically suggested to originally be underdeveloped.

2.
Stud Health Technol Inform ; 264: 1518-1519, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438210

RESUMO

Laboratory tests results have potential secondary usage. Each healthcare facility has a laboratory test code. Hence, test code mapping is required to support laboratory technicians. An automatic code mapping can reduce the burden of manual mapping during data preparation. The authors developed a semi-automatic mapping support system that uses the newest test results generated in the electronic health record.


Assuntos
Registros Eletrônicos de Saúde
3.
J Craniofac Surg ; 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31449225

RESUMO

Infantile immature teratoma located in the nasopharynx is a rare congenital tumor that is not easily removed. Three surgeries and chemotherapy for recurrence of the tumor have been performed since a male infant with a nasopharyngeal mass was born at a gestational age of 35 weeks. Extended maxillotomy combining Le Fort I osteotomy with midline palatal split was performed at 2 years and 6 months of age. Residual tumor left in the intracranial region had not increased as of 4 years of age. Careful follow-up is needed until the patient reaches adulthood.

4.
Stud Health Technol Inform ; 264: 739-743, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438022

RESUMO

Electronic Health Records (EHRs) are at the heart of reforms aiming for improving the efficiency and quality of citizens healthcare services. Although there is still some skepticism, open source (OS) EHR is a growing phenomenon in health informatics. Given the widespread adoption of OS software (OSS) in several domains, including operating systems, and enterprise systems, the repeated shortfalls faced by healthcare organizations with dominant proprietary EHRs create an opportunity for other alternatives, such as OSS to demonstrate their abilities in addressing these well-documented problems, including inflexibility, high costs, and low interoperability. However, scholars have expressed extensive concerns about the sustainability of OS EHR. Recognizing that OSS project sustainability relies on their governance arrangements, this case study reports on the evolution of the governance and sustainability of a Japanese OS EHR project and provides rich insights to other open source EHR initiative stakeholders, including physicians, developers, researchers, and policymakers.


Assuntos
Registros Eletrônicos de Saúde , Governança Clínica , Humanos , Japão , Informática Médica , Software
5.
Stud Health Technol Inform ; 264: 1702-1703, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438301

RESUMO

Medication processes are consisted with multiple steps by professionals and consumers. Physicians prescribe drugs to patient with conformance, but sometimes they were changed to other drugs. We designed concept models to capture medication workflow process records by openEHR archetype models, and four templates were determined with each step of the medication process. We will show the detail of clinical modeling about medication workflow in this article.


Assuntos
Registros Eletrônicos de Saúde , Fluxo de Trabalho , Assistência à Saúde , Tratamento Farmacológico , Humanos
6.
J Artif Organs ; 2019 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-31327062

RESUMO

We studied a control method of rotary blood pumps (RBPs), which is called as the cardiac beat synchronization (CBS) system. Usually, RBPs operate at constant target rotational speed, meanwhile, the CBS system modulates target speed synchronizing with cardiac beat. We built a computer simulation method to evaluate the CBS system. This simulator acquires a mathematical model of a circulatory system including a RBP and can provide us the theoretical hemodynamics when our control method is applied. We compared theoretical results with experimental ones with the model focusing on both pulsatility and aortic valve (AV) opening interval enhanced by the CBS system. Our simulator could reproduce behavior of the circulatory system whether the RBP is connected or not. Comparison among no RBP, constant assist, systolic assist, and diastolic assist modes indicated that pulsatility is enhanced with systolic assist theoretically. While systolic assist decreased AV opening interval, diastolic assist made it longer than the ones in other control strategies.

7.
Artigo em Inglês | MEDLINE | ID: mdl-31272878

RESUMO

Patients with bilateral cleft lip and palate (BCLP) generally require several stages of treatment, and adequate maxillary development without orthognathic surgery is not easy to achieve. The purpose of this study was to determine short-term outcomes of orthodontic premaxillary setback (OPS) and premaxillary osteotomy (PO) for complete BCLP treatment. PATIENTS AND METHODS: Twenty-six patients with BCLP were consecutively treated for 4 years by a single surgeon. All patients were categorized by three indications for the first operation: OPS1, cheiloplasty + gingivoperiosteoplasty (GPP) + palatoplasty; OPS2, cheiloplasty + GPP; and PO, cheiloplasty + GPP + PO. Cephalograms for maxillary growth and velopharyngeal function (VPF) were judged at 4 years old, before orthodontic treatment. RESULTS: OPS1 was performed in 14 cases, OPS2 in 8 cases, and PO in 4 cases. As for cephalometric analysis at 4 years old, no significant differences between groups were seen in any cephalometric measurements. As for speech outcomes, assessment of VPF at 80.8±14.8 months was good in 17 cases, slightly impaired in 8 cases, and marginally impaired in 1 case, with no severely impaired cases. DISCUSSION: No significant differences in maxillary growth or speech outcomes were seen between OPS1, OPS2, and PO groups at 4 years old, possibly because all groups showed the same position of the premaxilla after the first operation. CONCLUSIONS: No significant differences in maxillary growth or speech outcomes were seen for 26 patients with BCLP between OPS1, OPS2, and PO groups at 4 years old. However, the long-term growth characteristics remain unclear.

8.
Yearb Med Inform ; 28(1): 47-51, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31022753

RESUMO

OBJECTIVES: Artificial Intelligence (AI) offers significant potential for improving healthcare. This paper discusses how an "open science" approach to AI tool development, data sharing, education, and research can support the clinical adoption of AI systems. METHOD: In response to the call for participation for the 2019 International Medical Informatics Association (IMIA) Yearbook theme issue on AI in healthcare, the IMIA Open Source Working Group conducted a rapid review of recent literature relating to open science and AI in healthcare and discussed how an open science approach could help overcome concerns about the adoption of new AI technology in healthcare settings. RESULTS: The recent literature reveals that open science approaches to AI system development are well established. The ecosystem of software development, data sharing, education, and research in the AI community has, in general, adopted an open science ethos that has driven much of the recent innovation and adoption of new AI techniques. However, within the healthcare domain, adoption may be inhibited by the use of "black-box" AI systems, where only the inputs and outputs of those systems are understood, and clinical effectiveness and implementation studies are missing. CONCLUSIONS: As AI-based data analysis and clinical decision support systems begin to be implemented in healthcare systems around the world, further openness of clinical effectiveness and mechanisms of action may be required by safety-conscious healthcare policy-makers to ensure they are clinically effective in real world use.

9.
J Asthma ; 56(11): 1147-1158, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30822174

RESUMO

Background: There are limited data on the prevalence and burden of severe eosinophilic asthma (SEA) both in Japan and globally. This study aimed to assess the prevalence and burden of SEA in Japan. Methods: This study was a retrospective, observational cohort analysis using health records or health insurance claims from patients with severe asthma treated at Kyoto University Hospital. The primary outcome was the prevalence of SEA, defined as a baseline blood eosinophil count ≥300 cells/µL. Secondary outcomes included frequency and risk factors of asthma exacerbations, and asthma-related healthcare resource utilization and costs. Results: Overall, 217 patients with severe asthma were included; 160 (74%) had eosinophil assessments. Of these, 97cases (61%), 54cases (34%), and 33cases (21%) had a blood eosinophil count ≥150, ≥300, and ≥500 cells/µL, respectively. Proportion of SEA was 34%. Blood eosinophil count was not associated with a significantly increased frequency of exacerbations. In the eosinophilic group, lower % forced expiratory volume in 1 second and higher fractional exhaled nitric oxide were predictive risk factors, while the existence of exacerbation history was a predictive risk factor for asthma exacerbations in the non-eosinophilic group. Severe asthma management cost was estimated as ¥357,958/patient-year, and asthma exacerbations as ¥26,124/patient-year. Conclusions: Approximately, one-third of patients with severe asthma in Japan have SEA. While risk factors for exacerbations differed between SEA and severe non-eosinophilic asthma, both subgroups were associated with substantial disease and economic burden. From subgroup analysis, blood eosinophil counts could be an important consideration in severe asthma management.

10.
J Craniofac Surg ; 2018 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-30444777

RESUMO

INTRODUCTION: Treatment of patients with severe Pfeiffer syndrome types II and III is difficult. The purpose of this article is to present our method of overcorrecting midface advancement to improve airway problems in such patients. MATERIALS AND METHODS: One boy and two girls with types II and III Pfeiffer syndrome and who underwent Le Fort III midface advancement using our previously described corrected cephalometric analysis and distraction system were included in the study. RESULTS: The authors overcorrected by advancing the midface to make it look as similar as possible to an adult face. While the overcorrected midface advancement widened the upper airway spaces in the 3 patients, the tracheostomy that had already been placed during infancy could not be closed, probably because of an underlying tracheal abnormality or tracheomalacia. DISCUSSION: Overcorrected midface advancement cannot enable tracheostomy closure, probably because of severe tracheal anomalies, such as tracheomalacia, below the tracheostomy. However, with the possibility of gradual improvement of the tracheomalacia with age, closure of the tracheostomy can eventually be expected. Therefore, efforts to close a tracheostomy should be pursued even if the probability of its removal is low. CONCLUSION: Overcorrected midface advancement did not enable tracheostomy closure, probably because of severe tracheal anomalies such as tracheomalacia. However, the severe exophthalmos and angle III malocclusion were improved, and with the possibility of gradual improvement of the tracheomalacia with age, closure of the tracheostomy can eventually be expected. Therefore, efforts to close a tracheostomy should be pursued even if the probability of its removal is low.

11.
J Craniofac Surg ; 2018 Nov 09.
Artigo em Inglês | MEDLINE | ID: mdl-30418289

RESUMO

Le Fort II and III procedures have generally been performed for syndromic craniosynostosis with midfacial hypoplasia and skeletal class III malocclusion. However, some patients have midfacial hypoplasia without malocclusion. Perinasal osteotomy was performed with distraction osteogenesis to move the midface forward in 2 patients (a 17-year old female patient with Crouzon-like disease and a 15-year-old female patient with Antely-Bixler syndrome) with mild midface hypoplasia without malocclusion. The success of the procedure was assured by 3 features: the intermaxillary sutures were fixed by a mini metal plate to prevent separation during distraction; the distraction wires were fixed through the bone of the piriform aperture with the mini metal plates to prevent the wires from coming off; and the osteotomy line was designed in front of the palatomaxillary suture to avoid suture damage. These were expected to secure the procedure. Perinasal osteotomy with distraction osteogenesis is considered one of the recommended procedures for mild midfacial hypoplasia as seen in mild syndromic craniosynostosis without malocclusion.

12.
Artigo em Inglês | MEDLINE | ID: mdl-30276223

RESUMO

Only one case of second ipsilateral autologous reconstruction for the same breast that had previously undergone reconstruction has been reported. Here we present a patient who underwent breast reconstruction twice using free flap from different donor sites, using a buttock after a local recurrence following the previous reconstruction with a lower abdomen.

13.
Yearb Med Inform ; 27(1): 41-47, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29681042

RESUMO

OBJECTIVE: The International Medical Informatics Association (IMIA) Open Source Working Group (OSWG) initiated a group discussion to discuss current privacy and security issues in the open data movement in the healthcare domain from the perspective of the OSWG membership. METHODS: Working group members independently reviewed the recent academic and grey literature and sampled a number of current large-scale open data projects to inform the working group discussion. RESULTS: This paper presents an overview of open data repositories and a series of short case reports to highlight relevant issues present in the recent literature concerning the adoption of open approaches to sharing healthcare datasets. Important themes that emerged included data standardisation, the inter-connected nature of the open source and open data movements, and how publishing open data can impact on the ethics, security, and privacy of informatics projects. CONCLUSIONS: The open data and open source movements in healthcare share many common philosophies and approaches including developing international collaborations across multiple organisations and domains of expertise. Both movements aim to reduce the costs of advancing scientific research and improving healthcare provision for people around the world by adopting open intellectual property licence agreements and codes of practice. Implications of the increased adoption of open data in healthcare include the need to balance the security and privacy challenges of opening data sources with the potential benefits of open data for improving research and healthcare delivery.


Assuntos
Confidencialidade , Bases de Dados Factuais , Disseminação de Informação , Segurança Computacional , Conjuntos de Dados como Assunto , Assistência à Saúde , Humanos , Informática Médica , Sociedades Médicas
14.
Plast Reconstr Surg Glob Open ; 5(11): e1402, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29263944

RESUMO

Background: In bilateral cleft lip and palate (BCLP) patients with protrusion and/or torsion of the premaxillae, it is difficult to achieve a good outcome. We have developed a series of procedures of premaxillary osteotomy with primary cheiloplasty for BCLP patients who did not respond well to presurgical orthodontics (PSO). Methods: A total of 27 BCLP patients with protrusion and/or torsion of the premaxillae underwent PSO. For 3 BCLP patients in whom the protruded premaxillae could not be returned to a good position, a primary premaxillary osteotomy and gingivoperiosteoplasty (GPP) with cheiloplasty were performed simultaneously. Subsequently, Furlow palatoplasty was performed by one and a half years of age. Maxillary growth was evaluated by dental occlusion at 4 years of age. Results: A premaxillary osteotomy and GPP with cheiloplasty were performed at 6 months. The patients' facial structures improved, their premaxillae were positioned more superiorly, and normal inclination of the incisors was achieved. They had edge-to-edge occlusions or cross bites at 4 years of age. Conclusions: As advantages, the patients' facial structures improved, and the alveolar bones were formed by GPP. As a disadvantage, premaxillary necrosis might occur because of poor blood circulation. It is important to secure the following 2 blood supplies: from the periosteum and soft-tissue of the anterior premaxillae and from the periosteum and mucosa of the nasal septum. Synchronous premaxillary osteotomy and GPP with primary cheiloplasty are appropriate when the premaxillae cannot be properly repositioned by PSO or PSO cannot be done.

15.
Plast Reconstr Surg Glob Open ; 5(9): e1482, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29062650

RESUMO

BACKGROUND: The purpose of this study was to confirm the utility of a corrected cephalometric analysis to facilitate the planning of distraction osteogenesis with Le Fort III osteotomy for syndromic craniosynostosis. METHODS: This prospective study involved 4 male and 2 female patients (mean patient age, 8 years 9 months; age range, 4 years 6 months to 13 years 2 months) with Crouzon syndrome who were treated with Le Fort III maxillary distraction using our previously described system of analysis of a corrected cephalogram and who underwent clinical follow-up. Lateral cephalograms were obtained immediately after device removal. RESULTS: Distraction of orbitale moved the vector downward to the adult profile, but there was slightly less elongation than the adult profile for the distraction distance. The desired and real mean angles after distraction of point A were 29.2 ± 7.9° and 6.1 ± 8.5°, respectively, and the desired and the real mean distances after distraction of point A were 30.6 ± 12.7 mm and 29.4 ± 4.1 mm, respectively. CONCLUSIONS: Using the corrected cephalometric analysis, the distance and vector of distraction osteogenesis with Le Fort III osteotomy could be determined in patients with syndromic craniosynostosis. The distraction system brought the patients' facial bones to the planned position using controlling devices.

16.
Tohoku J Exp Med ; 242(4): 327-334, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-28883214

RESUMO

Atypical femoral fractures (AFFs) have been reported to occur with minimal or spontaneous subtrochanteric and femoral shaft fractures with a characteristic transverse pattern, compared with typical femoral fractures in young patients with high-energy trauma. AFFs are related to long-term use of bisphosphonates (BPs), glucocorticoids and rheumatic diseases. We have estimated a blind analysis of AFFs in rheumatic patients receiving BPs and glucocorticoids ordinary over a long time in all Yamagata prefectural area through radiographic examination. The 123 AFFs including suspected cases over six years were collected and reviewed by two independent orthopedic surgeons. We found 86 patients with a total of 99 AFFs between 2009 and 2014 (1.43 cases/100,000 person/year). Of these 99 AFFs, 11 were in 8 rheumatic patients including three patients with bilateral AFFs. The incidence of AFFs in rheumatic patients had trend to increase from 2012. The mean age of all 8 patients was 54.9 years. All 8 patients received BPs and 7/8 received prednisolone (PSL). The mean dose of PSL was 14 mg/day. Compared to patients with unilateral AFFs, those with bilateral AFFs in rheumatic patients were on a higher dose of PSL (20 mg/day vs. 7 mg/day) and had less femoral neck-shaft angle (129° vs. 136°, p < 0.05). In conclusion, the incidence of AFFs in rheumatic patients showed a trend to increase from 2012 to 2014 in Yamagata prefecture. Careful management of AFFs is of particular importance in rheumatic patients who have taken high doses of PSL and have small femoral neck-shaft angle.


Assuntos
Fraturas do Fêmur/complicações , Fraturas do Fêmur/epidemiologia , Doenças Reumáticas/complicações , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Fraturas do Fêmur/diagnóstico por imagem , Humanos , Incidência , Japão/epidemiologia , Masculino , Pessoa de Meia-Idade , Doenças Reumáticas/diagnóstico por imagem , Doenças Reumáticas/epidemiologia
17.
Lasers Surg Med ; 49(8): 750-755, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28432775

RESUMO

INTRODUCTION: Liposuction and mesotherapy are popular treatments for fat reduction of lower face, but because these treatments are invasive, a novel non-invasive treatment with similar or better efficacy has been sought. There are various devices such as CoolSculpt, laser, RF, and HIFU that are used as non-invasive treatments for fat reduction and body contouring, but these applications have not been applied to facial fat reduction. In this study, we selected Monopolar 1-MHz RF for body contouring to be applied for fat reduction and tightening of the lower face. MATERIAL AND METHODS: From March through August of 2016, we treated fourteen Asian women (average age: 44.6 years old) for fat reduction and tightening of the lower face using 1-MHz Monopolar RF (truSculpt™, Cutera, Inc., Brisbane, CA). We performed the treatment primarily in the nasolabial fold and buccal area weekly for five consecutive weeks, and evaluated the effects for fat reduction and tightening before each treatment and for 2 months after the treatment using handy VECTRA 3D® (Canfield Scientific, Inc.) for imaging. Three-dimensional (3D) volumetric assessments were performed at pre- and post-two-months after treatment. Patients rated their satisfaction for tightening using a 5-points scale. RESULTS: During the study, more than ninety percent of patients showed volumetric change by fat reduction at the treated area, with an average of 2.7 ml. Sixty percent of patients were either "satisfied" or "very satisfied" with the tightening effects. The treatments were accompanied only by very mild heat pain. Efficacy was maintained for 2 months after the treatments, and three patients showed a higher fat reduction effect at 2 months after the final treatment compared with the final treatment. A mild redness was observed just for few hours after the treatment, but complications such as, swelling, induration, burn, sensory disturbance or facial paralysis, were not observed. CONCLUSION: In this study, we found that Monopolar 1-MHz RF applied with a stationary applicator was effective especially for lower face fat reduction and with a tightening effect in facial contouring. A highly efficacious treatment with satisfactory comfort and safety can be achieved with no downtime, and the device has the potential for becoming one of the standard non-invasive treatments for fat reduction of facial contouring. Lasers Surg. Med.49:750-755, 2017. © 2017 Wiley Periodicals, Inc.


Assuntos
Contorno Corporal/métodos , Face/cirurgia , Ondas de Rádio/uso terapêutico , Gordura Subcutânea/cirurgia , Adulto , Grupo com Ancestrais do Continente Asiático , Feminino , Humanos , Pessoa de Meia-Idade , Avaliação de Resultados (Cuidados de Saúde) , Satisfação do Paciente/estatística & dados numéricos
18.
Lymphat Res Biol ; 15(1): 77-86, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-28323573

RESUMO

BACKGROUND: Intermittent pneumatic compression (IPC) is a widely used lymph drainage therapy that can be performed at home. However, the effectiveness of IPC for lymph drainage remains unclear. The aim of this study is to investigate the real-time change in the lymph flow velocity during IPC and consider which mode and pressure are best for treating lower limb lymphedema. METHODS AND RESULTS: Eight lower left limbs of 8 healthy volunteers and 17 lower limbs of 15 secondary lymphedema patients were investigated. Indocyanine green lymphography was performed with the subject covered with a transparent six-chambered IPC garment. The IPC treatment was administered in several modes (sequential or nonsequential inflation mode, sequential or interrupted deflation mode, and under high or low pressure). Using a brightness intensity analysis software program, the real-time change in the fluorescence intensity during the treatment was recorded and graphed. The maximum inclination of the graph between 2 seconds in the inflation phase (SLOPE) and the mean SLOPE value of all subjects (average SLOPE) were calculated. The average SLOPEs of each mode of treatment were then compared. The average SLOPEs were also compared between patients with mild and moderate lymphedema. There were no significant differences among the SLOPEs in the healthy group. However, in the patient group, the average SLOPE was significantly higher in the sequential inflation mode as well as under high pressure than in the nonsequential inflation mode. On comparing the mild and moderate lymphedema groups, the average SLOPE tended to be higher in the mild group; however, the difference was not statistically significant. CONCLUSIONS: Sequential programs and high pressure resulted in a faster lymphatic flow than other modes. These results suggest that a greater treatment effect could be obtained by adjusting the mode of treatment and the pressure of IPC.


Assuntos
Dispositivos de Compressão Pneumática Intermitente , Extremidade Inferior/fisiopatologia , Vasos Linfáticos/fisiopatologia , Linfedema/fisiopatologia , Linfedema/terapia , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Casos e Controles , Feminino , Humanos , Linfedema/diagnóstico , Linfedema/etiologia , Linfocintigrafia , Masculino , Pessoa de Meia-Idade , Imagem Óptica/métodos , Pressão , Resultado do Tratamento , Adulto Jovem
19.
Neurosci Res ; 114: 30-34, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-27553707

RESUMO

Spinal reflex arcs mediated by low-threshold (group I) afferents from muscle spindles and Golgi tendon organs modulate motoneuron excitabilities to coordinate smooth movements. In this study, the reflex arcs between the brachioradialis (BR) and extensor carpi radialis muscles (ECR) were examined in nine healthy human subjects using a post-stimulus time-histogram method. Electrical conditioning stimuli (ES) to the radial nerve branches innervating BR (BR nerve) and ECR (ECR nerve) with the intensity just below the motor threshold were delivered and firings of the ECR and BR motor units were recorded in 6 and 7 of the nine subjects, respectively. ES to the BR and ECR nerves induced a peak (facilitation) in 27/59 ECR and 22/68 BR motor units, respectively, in every subject. Such facilitation was never provoked by pure cutaneous stimulation. The remaining motor units received no effects by ES. The central synaptic delay of the facilitation was almost equal to that of the homonymous facilitation. These findings suggest that facilitation between BR and ECR exists in humans. Group I afferents should mediate the facilitation through a monosynaptic path in the spinal cord.


Assuntos
Vias Aferentes/fisiologia , Cotovelo/fisiologia , Potencial Evocado Motor/fisiologia , Músculo Esquelético/fisiologia , Reflexo/fisiologia , Adulto , Cotovelo/inervação , Estimulação Elétrica , Eletromiografia , Feminino , Humanos , Masculino , Músculo Esquelético/inervação , Condução Nervosa/fisiologia , Tempo de Reação , Punho/inervação , Adulto Jovem
20.
Stud Health Technol Inform ; 245: 1266, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29295351

RESUMO

openEHR is a widely used EHR specification. Given its technology-independent nature, different approaches for implementing openEHR data repositories exist. Public openEHR datasets are needed to conduct benchmark analyses over different implementations. To address their current unavailability, we propose a method for generating openEHR test datasets that can be publicly shared and used.


Assuntos
Acesso à Informação , Benchmarking , Conjuntos de Dados como Assunto , Registros Eletrônicos de Saúde , Humanos , Disseminação de Informação , Software
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