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1.
Malawi Med J ; 33(1): 15-20, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-34422229

RESUMO

Purpose: To evaluate the clinical and socio-demographic profile of patients living with glaucoma and receiving care in a tertiary eye center in Zimbabwe. Method: A hospital-based retrospective study of clinical records of glaucoma patients from January 2014 to December 2018. The study involved collating demographic information of patients, visual acuities, (VA) intraocular pressure, (IOP), cup-to-disc ratios, (CDRs), average retinal nerve fibers thickness, (RNFL), cup volume, cup-to-disc area, vertical cup-to-disc ratio, (VCDR), rim area, disc area, glaucoma hemifield test, visual field indices and the management of glaucoma. Results: Nine thousand one hundred and eighty-five (9,185) folders were retrieved. Out of these, 432 (4.7%) qualified for the study and were analyzed. There were 267 (61.8%) males and 165 (38.2%) females. The mean age (± Standard deviation, SD) of the patients was 62.66 ± 15.94 years, (range 10 - 110 years). The means visual acuity (VA): OD =1.30 ± 1.06 Logarithm of the Minimum Angle of Resolution, (logMAR), OS = 1.33 ± 1.06 logMAR; IOP: OD = 29.51 ± 12.89 mmHg, OS: 29.17 ± 12.59 mmHg; CDRs: OD = 0.91 ± 0.14 D, OS = 0.92 ± 0.14 D; and the average RNFL thickness was 72.76 ± 18.26 µm and 71.24 ± 23.17 µm in the right and left eye respectively. The mainstay of treatment was medication only. Conclusion: There were more males than females receiving glaucoma care at the tertiary level. Glaucoma cases included juveniles but the mean age was mostly the elderly. It was characterized by high IOPs, large CDRs, and thin RNFL suggestive of late presentation.


Assuntos
Glaucoma/diagnóstico , Glaucoma/epidemiologia , Encaminhamento e Consulta/estatística & dados numéricos , Adolescente , Adulto , Grupo com Ancestrais do Continente Africano , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Glaucoma/terapia , Glaucoma de Ângulo Aberto/epidemiologia , Humanos , Pressão Intraocular/fisiologia , Masculino , Pessoa de Meia-Idade , Fibras Nervosas/patologia , Retina/anatomia & histologia , Estudos Retrospectivos , Fatores Socioeconômicos , Campos Visuais/fisiologia , Adulto Jovem , Zimbábue/epidemiologia
2.
PLoS One ; 16(1): e0245486, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33449975

RESUMO

The purpose of this study was to evaluate the epidemiological and clinical profile of patients living with glaucoma and receiving care in a tertiary eye center in Ghana. This was a hospital-based retrospective study of clinical records of glaucoma patients from January 2010 to December 2019. The study involved collating demographic information of patients, clinical presentation, and the management of glaucoma. A total of nineteen thousand (19,000) charts were retrieved from the eye center's archives. Out of these, 660 (3.5%) records of patients qualified for the study and were analyzed. There were 398 (60.3%) males and 262 (39.7%) females. Their ages ranged from 9 to 86 years (mean age = 47.30; SD ± 16.86 years). The averages of ocular parameters of 1,320 eyes (660 patients) were visual acuity = 0.26 ± 0.55 logMAR; intraocular pressure: 17.31 ± 6.11 mmHg; cup-to-disc ratios: 0.67 ± 0.17 D; and the average retinal nerve fibers thickness was 95.03 ± 21.74 µm. The mainstay of treatment was the sole use of medication. Males were the major group receiving glaucoma care at the tertiary level. Glaucoma cases included juveniles but the mean age suggests most were of adult-onset. Socio-demographic characteristics affected the diagnosis and management of glaucoma among patients receiving care at a referral center. Public health, stakeholders, and policymakers' interventions can help identify individuals with glaucoma.


Assuntos
Glaucoma/epidemiologia , Saúde Pública , Encaminhamento e Consulta/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Gana/epidemiologia , Glaucoma/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
3.
Int Ophthalmol ; 41(3): 981-990, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33185821

RESUMO

PURPOSE: The objective of this study was to determine the structure-function association of the optical coherence tomography (OCT) indices (retinal nerve fibre layer (RNFL), ganglion cell complex (GCC) and optic nerve head (ONH) parameters) with the visual field sensitivity and their diagnostic ability at different stages of primary open-angle glaucoma (POAG) among a population West-African descent. METHODS: The study was a clinic-based prospective study which employed purposive sampling in the recruitment of clinically diagnosed POAG and non-glaucoma patients. OCT and visual field test (VFT) results were collated. Classification of the POAG cases was done using the Hodapp-Parrish-Anderson criteria. ROC was used for assessing the diagnostic ability of OCT indices. Pearson's correlation was used to assess the structure-function association. P value < 0.05 was considered statistically significant. CONCLUSIONS: Of the 497 subjects (497 eyes), 301 (60.6%) were males and 196 (39.4%) were females. The average, superior and inferior RNFL and GCC showed a strong positive correlation with the visual field sensitivity, but the average RNFL had the highest correlation (r = 0.673, p < 0.001). The parameters of the ONH showed a moderate-to-weak correlation with the visual field sensitivity. However, there was no significant correlation between structure and function in early POAG (p > 0.05). Superior GCC showed the highest diagnostic ability for POAG (AUC = 0.655; p < 0.001) comparable to the RNFL. Macula (GCC) and (RNFL) have a comparable ability to diagnose POAG at all the stages of POAG and can be used complimentarily for glaucoma assessment and diagnosis.


Assuntos
Glaucoma de Ângulo Aberto , Estudos Transversais , Feminino , Glaucoma de Ângulo Aberto/diagnóstico , Humanos , Pressão Intraocular , Masculino , Fibras Nervosas , Estudos Prospectivos , Células Ganglionares da Retina , Tomografia de Coerência Óptica
4.
Ethiop J Health Sci ; 30(6): 999-1004, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33883845

RESUMO

Background: The aim of this study was to determine whether Central Corneal Thickness (CCT) is associated with intraocular pressure measurement (IOP) with a Non-contact tonometer and the Goldmann applanation tonometer in glaucoma patients. Materials and Methods: The study involved two hundred and thirty-two eyes of clinically diagnosed glaucoma patients receiving care at a referral facility. IOP measurements were obtained using both the Non-Contact Tonometer (NCT) and Goldmann Applanation Tonometer (GAT). The association between age, ethnicity, and CCT, as well as CCT on the measures of NCT and GAT, were analyzed. Results: There were 64(55.2%) males and 52 (44.8%) females and their ages ranged from 18 to 85 years (mean age = 47.72; SD ± 15.75 years). There was a weak positive correlation between the CCT and NCT findings in the right eye (r = 0.19, n = 116, p < 0.05) and in the left eye (r = 0.25, n = 116, p < 0.05). However, there was no correlation between CCT and GAT measurements. Age had a significant correlation with CCT while gender and ethnicity had no significant correlation. Conclusion: The study found a significant association between CCT and NCT. However, there was no significant association between CCT and GAT. CCT had an association with age but independent of gender and ethnicity since there was no significant relationship between these variables.


Assuntos
Glaucoma , Pressão Intraocular , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Córnea , Feminino , Glaucoma/diagnóstico , Humanos , Masculino , Manometria , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Tonometria Ocular , Adulto Jovem
5.
Afr Health Sci ; 19(4): 2945-2953, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32127869

RESUMO

Aim: To design and validate a MNREAD Asante Twi version reading chart, to aid in the assessment of near visual acuity of natives Ghanaians. Methods: Cross-sectional and experimental designs were employed in phases I and II respectively of this study. The chart was developed using 20 transited pupils in class four in the Kumasi metropolis in phase I and validated in a clinical setting at the Manhyia District Hospital, Kumasi, using students in phase II. Results: A total of 100 participants (mean age; 22.19 ± 1.61 years) were involved in the second phase of this study. A Pearson product-moment correlation coefficient was computed to assess the relationship between MNREAD Asante Twi charts logMAR scores in both eyes. The MNREAD-Asante Twi acuity charts had very strong correlations (r = 0.94, p < 0.001) for MNREAD set 1A (black on white background) scores and MNREAD set 2A (black on white background) for acuity scores. Correlation between MNREAD set 1B (white on black background) scores and MNREAD set 2B (white on black background) scores was r = 0.95, p < 0.001. Conclusion: MNREAD Asante Twi reading chart will enhance the measurement of near visual function in native Ghanaians.


Assuntos
Leitura , Testes Visuais/normas , Baixa Visão , Acuidade Visual/fisiologia , Adolescente , Estudos Transversais , Feminino , Gana , Humanos , Masculino , Reprodutibilidade dos Testes , Adulto Jovem
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