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1.
PLoS One ; 15(11): e0242210, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33211733

RESUMO

BACKGROUND: Around 50% of hospital readmissions due to heart failure are preventable, with lack of adherence to prescribed self-care as a driving factor. Remote tracking and reminders issued by mobile health devices could help to promote self-care, which could potentially reduce these readmissions. OBJECTIVE: We sought to investigate two factors: (1) feasibility of enrolling heart failure patients in a remote monitoring regimen that uses wireless sensors and patient-reported outcome measures; and (2) their adherence to using the study devices and completing patient-reported outcome measures. METHODS: Twenty heart failure patients participated in piloting a remote monitoring regimen. Data collection included: (1) physical activity using wrist-worn activity trackers; (2) body weight using bathroom scales; (3) medication adherence using smart pill bottles; and (4) patient -reported outcomes using patient-reported outcome measures. RESULTS: We evaluated 150 hospitalized heart failure patients and enrolled 20 individuals. Two factors contributed to 50% (65/130) being excluded from the study: smartphone ownership and patient discharge. Over the course of the study, 60.0% of the subjects wore the activity tracker for at least 70% of the hours, and 45.0% used the scale for more than 70% of the days. The pill bottle was used less than 10% of the days by 55.0% of the subjects. CONCLUSIONS: Our method of recruiting heart failure patients prior to hospital discharge may not be feasible as the enrollment rate was low. Once enrolled, the majority of subjects maintained a high adherence to wearing the activity tracker but low adherence to using the pill bottle and completing the follow-up surveys. Scale usage was fair, but it received positive reviews from most subjects. Given the observed usage and feedback, we suggest mobile health-driven interventions consider including an activity tracker and bathroom scale. We also recommend administering a shorter survey more regularly and through an easier interface.

2.
Hu Li Za Zhi ; 67(5): 26-32, 2020 Oct.
Artigo em Chinês | MEDLINE | ID: mdl-32978763

RESUMO

The popularization of smart technology is a global phenomenon. The increasing ubiquity of smartphones offers the potential to apply smart technology in areas such as healthcare and behavioral change interventions. Mobile health services may enhance the effectiveness and resolve the shortcomings of traditional medical services, which cannot continuously and instantly track changes in disease symptoms. The popularity of mobile phones has led to the emergence of mobile health applications. Mobile health applications use active and passive methods to collect data and transmit information. Studies have confirmed the feasibility and acceptance of these applications in assessing and detecting diseases and in mental health interventions. In this article, the limitations of traditional psychiatric medical diagnosis and the opportunity to develop mobile health using information and communication technology are discussed, and related empirical research on using smart technology to evaluate and detect symptoms is explored using the example of bipolar disorders. In addition, the benefits and future prospects of onset alert and the development of healthcare models for action are highlighted. In the future, we look forward to developing mobile health applications that meet the needs of healthcare in Taiwan. Furthermore, we recommend more research and investment in related fields to accumulate more extensive empirical evidence.


Assuntos
Transtornos Mentais/terapia , Aplicativos Móveis , Smartphone , Telemedicina/métodos , Humanos , Taiwan
3.
J Tissue Viability ; 2020 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-32773358

RESUMO

AIM: This study aimed to develop and test the validity and reliability of the Knowledge, Attitudes and Practices of Incontinence-associated Dermatitis Questionnaire (KAP-IAD-Q) for Nurses. METHODS: A psychometric validation design was employed. Phase I of the study entailed the development of items through an extensive literature review and a double Delphi procedure with 11 experts specialised in wound, ostomy and continence to examine content validity of the KAP-IAD-Q. Phase II involved administering the KAP-IAD-Q to a convenience sample of 263 Registered Nurses from a public hospital in Singapore to evaluate its construct validity, internal consistency and test-retest reliability. RESULTS: The instrument showed acceptable content validity (S-CVI = 0.85). Exploratory factor analysis showed all 22 items demonstrated strong factor loadings >0.4 and the four factors KAP-IAD-Q explained 58.1% of total variance. The four factors were☹1) knowledge om IAD aetiology and identification, (2) knowledge on IAD risk factors; (3) attitudes, and (4) practices. The overall internal consistency was excellent (Cronbach's α = 0.913). The KAP-IAD-Q showed good overall test-retest reliability as well (ICC = 0.89 (95% CI 0.69-0.96, p < 0.001). CONCLUSION: The KAP-IAD-Q demonstrated good psychometric properties and is effective in measuring levels of IAD-related KAP among nurses. Further confirmation of the proposed factor structure is recommended. Future research should explore determinants of nurses' KAP and associations between IAD knowledge, attitudes and practices.

4.
JMIR Cardio ; 3(2): e14332, 2019 Oct 29.
Artigo em Inglês | MEDLINE | ID: mdl-31758788

RESUMO

BACKGROUND: Heart failure is a serious public health concern that afflicts millions of individuals in the United States. Development of behaviors that promote heart failure self-care may be imperative to reduce complications and avoid hospital re-admissions. Mobile health solutions, such as activity trackers and smartphone apps, could potentially help to promote self-care through remote tracking and issuing reminders. OBJECTIVE: The objective of this study was to ascertain heart failure patients' interest in a smartphone app to assist them in managing their treatment and symptoms and to determine factors that influence their interest in such an app. METHODS: In the clinic waiting room on the day of their outpatient clinic appointments, 50 heart failure patients participated in a self-administered survey. The survey comprised 139 questions from previously published, institutional review board-approved questionnaires. The survey measured patients' interest in and experience using technology as well as their function, heart failure symptoms, and heart failure self-care behaviors. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) was among the 11 questionnaires and was used to measure the heart failure patients' health-related quality of life through patient-reported outcomes. RESULTS: Participants were aged 64.5 years on average, 32% (16/50) of the participants were women, and 91% (41/45) of the participants were determined to be New York Heart Association Class II or higher. More than 60% (30/50) of the survey participants expressed interest in several potential features of a smartphone app designed for heart failure patients. Participant age correlated negatively with interest in tracking, tips, and reminders in multivariate regression analysis (P<.05). In contrast, MLHFQ scores (worse health status) produced positive correlations with these interests (P<.05). CONCLUSIONS: The majority of heart failure patients showed interest in activity tracking, heart failure symptom management tips, and reminder features of a smartphone app. Desirable features and an understanding of factors that influence patient interest in a smartphone app for heart failure self-care may allow researchers to address common concerns and to develop apps that demonstrate the potential benefits of mobile technology.

5.
Hu Li Za Zhi ; 65(2): 64-74, 2018 Apr.
Artigo em Chinês | MEDLINE | ID: mdl-29564858

RESUMO

BACKGROUND: The ideology of recovery addresses the autonomy of patients with mental illness and their ability to reconstruct a normal life. Empirical knowledge of this process of recovery and related factors remains unclear. PURPOSE: To assess the process of recovery and related factors in patients with mental illness. METHODS: This cross-sectional, correlational study was conducted on a convenience sample in a psychiatric hospital. Two-hundred and fifty patients with mental illness were recruited and were assessed using 3 instruments: Questionnaire about the Process of Recovery (QPR), Perceived Psychiatric Stigma Scale (PPSS), and Personal and Social Performance Scale (PSP). Data were analyzed using descriptive statistics, χ2, analysis of variance, and multiple linear regression analysis. RESULTS: Most of the participants were male, middle-aged, unmarried, educated to the senior high school level, employed, receiving home-care treatment, and diagnosed with schizophrenia. Those who were unemployed, living in a community rehabilitative house, and living in the community, respectively, earned relatively higher recovery scores (p < .05). The total scores of QPR and the 3 subscales were negatively correlated with PPSS (p < .01) and positively correlated with PSPS (p < .01; p < .05). Multiple regression analysis indicated that the factors of education, employment, having received community rehabilitative models, and stigma, respectively, significantly explained the recovery capacity of patients with mental illness. CONCLUSIONS: Community psychiatric nurses should provide care to help employed patients adapt to stresses in the workplace, strengthen their stigma-coping strategies, and promote public awareness of mental health issues by increasing public knowledge and acceptance of mental illness in order to minimize patient-perceived stigma and facilitate their recovery.


Assuntos
Transtornos Mentais/psicologia , Adaptação Psicológica , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estigma Social
6.
Hu Li Za Zhi ; 64(5): 59-68, 2017 Oct.
Artigo em Chinês | MEDLINE | ID: mdl-28948592

RESUMO

BACKGROUND: The negative attitudes of the general public toward mental illness frequently influence the integration of mental illness patients into the community. Auditory hallucination simulation may be considered as a creative teaching strategy to improve the attitudes of learners toward mental illness. However, the empirical effects of auditory hallucination simulation to change the negative attitudes toward mental illness remains uncertain. PURPOSE: To compare and analyze, using a systematic review and meta-analysis, the effectiveness of auditory hallucination simulation in improving empathy, knowledge, social distance, and attitudes toward mental illness in undergraduates. METHODS: A search using the keywords "auditory hallucination" and "simulation" and the 4 outcome indicators of empathy, knowledge, social distance, and attitudes toward mental illness was conducted to identify related articles published between 2008 and 2016 in 6 Chinese and English electronic databases, including Cochrane Library, EBSCO-CINAHL, MEDLINE, PsycINFO, PubMed, and Airiti Library. Research quality was appraised using the Modified Jadad Scale (MJS), the Oxford Centre for Evidence-Based Medicine Level of Evidence (OCEBM LoE), and the Cochrane Risk of Bias tool. RESULTS: Eleven studies were recruited, and 7 studies with sufficient data were included in the meta-analysis. The meta-analysis showed that hallucination simulation significantly improved the empathy and knowledge of participants, with respective effect sizes of 0.63 (95% CI [0.21, 1.05]) and 0.69 (95% CI [0.43-0.94]). However, this intervention also increased social distance, with an effect size of 0.60 (95% CI [0.01, 1.19]), and did not change attitudes toward mental illness significantly, with an effect size of 0.33 (95% CI [-0.11, 0.77]). CONCLUSIONS / IMPLICATIONS FOR PRACTICE: Auditory hallucination simulation is an effective teaching strategy for improving the empathy and knowledge of undergraduates. However, related evidence for the effects of social distance and attitudes toward mental illness need to be further strengthened. Most of the extant research on this subject was conducted in the United States and Australia and was of moderate quality. Future studies should use sufficiently rigorous research designs to explore the safety issues and the effectiveness of the auditory hallucination simulation intervention in different countries and ethnic populations.


Assuntos
Atitude , Empatia , Alucinações , Conhecimento , Transtornos Mentais/psicologia , Estudantes/psicologia , Humanos , Projetos de Pesquisa
7.
Hu Li Za Zhi ; 64(3): 19-26, 2017 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-28580555

RESUMO

Bipolar disorder (BD) is a severe mental illness that is characterized by chronicity, pervasive instability, and relatively high rates of recurrence and suicide. Current evidence supports that adverse circles among hereditary and genetic factors, neuroinflamation, and social rhythm constitute a crucial etiology. Pharmacological treatment is the first priority for BD patients during the acute stage. Pharmacological and psychosocial treatments should be combined during the maintenance stage in order to help patients self-manage medication, effectively control mood swings, enhance disease self-management and social functions, decrease the risks of relapse and re-hospitalization, and stabilize overall health. The present article firstly introduces the characteristics and etiological assumptions related to BD, the related evidence-based care models and their effects, and the early development of an evidence-based care model, the BalancingMySwing group, for BD patients in Taiwan. This article provides updated information to clinicians who are involved in caring for this population. Moreover, the existing data related to biological and psychosocial factors for BD in Taiwan is insufficient and developing individual-tailored psychosocial intervention is urgently needed. The authors hope that this article will elicit greater concern for this issue from policy decision-makers and healthcare providers.


Assuntos
Transtorno Bipolar/terapia , Transtorno Bipolar/etiologia , Transtorno Bipolar/enfermagem , Enfermagem Baseada em Evidências , Humanos
8.
Adv Mater ; 29(20)2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28106303

RESUMO

Electrochemical energy storage technology is of critical importance for portable electronics, transportation and large-scale energy storage systems. There is a growing demand for energy storage devices with high energy and high power densities, long-term stability, safety and low cost. To achieve these requirements, novel design structures and high performance electrode materials are needed. Porous 1D nanomaterials which combine the advantages of 1D nanoarchitectures and porous structures have had a significant impact in the field of electrochemical energy storage. This review presents an overview of porous 1D nanostructure research, from the synthesis by bottom-up and top-down approaches with rational and controllable structures, to several important electrochemical energy storage applications including lithium-ion batteries, sodium-ion batteries, lithium-sulfur batteries, lithium-oxygen batteries and supercapacitors. Highlights of porous 1D nanostructures are described throughout the review and directions for future research in the field are discussed at the end.

9.
ACS Nano ; 10(1): 324-32, 2016 Jan 26.
Artigo em Inglês | MEDLINE | ID: mdl-26593851

RESUMO

Glucose oxidase-based biofuel cells are a promising source of alternative energy for small device applications, but still face the challenge of achieving robust electrical contact between the redox enzymes and the current collector. This paper reports on the design of an electrode consisting of glucose oxidase covalently attached to gold nanoparticles that are assembled onto a genetically engineered M13 bacteriophage using EDC-NHS chemistry. The engineered phage is modified at the pIII protein to attach onto a gold substrate and serves as a high-surface-area template. The resulting "nanomesh" architecture exhibits direct electron transfer (DET) and achieves a higher peak current per unit area of 1.2 mA/cm(2) compared to most other DET attachment schemes. The final enzyme surface coverage on the electrode was calculated to be approximately 4.74 × 10(-8) mol/cm(2), which is a significant improvement over most current glucose oxidase (GOx) DET attachment methods.


Assuntos
Bacteriófago M13/química , Fontes de Energia Bioelétrica , Elétrons , Glucose Oxidase/química , Glucose/química , Ouro/química , Técnicas Eletroquímicas , Eletrodos , Transporte de Elétrons , Enzimas Imobilizadas , Flavina-Adenina Dinucleotídeo/química , Nanopartículas/química , Oxirredução
10.
Hu Li Za Zhi ; 61(6): 48-56, 2014 Dec.
Artigo em Chinês | MEDLINE | ID: mdl-25464956

RESUMO

BACKGROUND: Public attitudes toward mental illness influence the success with which patients reenter the community. An attitude instrument suitable to the Chinese cultural setting with good reliability and validity is essential to examining public attitudes toward mental illness. Exploring the perspectives of adolescents is relevant because most mental illness occurs during adolescence. PURPOSE: This study developed and tested the psychometric quality of the Chinese-version Attitudes Toward Mental Illness (CAMI) scale among senior high school students. METHODS: The original AMI was translated into Chinese using a back and forth translation method and its content validity was examined. A cross-sectional survey of 479 senior high school students was conducted to assess the construct validity, cross validity, and internal consistency of the CAMI. RESULTS: The CAMI showed adequate content validity. The confirmatory factor analysis support: the appropriateness of CAMI's original two-factor structure of negative attitude and recovery outcomes after deleting items 9 and 11; the measurement of the negative perceptions of mentally ill patients and their risks to community; and the perceptions of recovery of mentally ill patients. The construct validity and cross validity are appropriate and the internal consistency of the total scale and two subscales are acceptable (Cronbach's α: .76, .75, .81). CONCLUSIONS / IMPLICATIONS FOR PRACTICE: The reliability and validity of the CAMI is appropriate for the sample of senior high students in this study. Future studies should target a broader range of people in order to establish the reliability and validity of the scale in different groups and to build up empirical knowledge on public attitudes toward mental illness. The application of this scale is expected to contribute to the development of anti-stigma interventions and to the creation of friendly communities for mentally ill patients.


Assuntos
Atitude Frente a Saúde , Transtornos Mentais/psicologia , Estudantes/psicologia , Humanos , Reprodutibilidade dos Testes
11.
ACS Appl Mater Interfaces ; 5(21): 10966-74, 2013 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-24175870

RESUMO

We have devised a moderate temperature hot-pressing route for preparing metal-matrix composites which possess tunable thermal expansion coefficients in combination with high electrical and thermal conductivities. The composites are based on incorporating ZrW2O8, a material with a negative coefficient of thermal expansion (CTE), within a continuous copper matrix. The ZrW2O8 enables us to tune the CTE in a predictable manner, while the copper phase is responsible for the electrical and thermal conductivity properties. An important consideration in the processing of these materials is to avoid the decomposition of the ZrW2O8 phase. This is accomplished by using relatively mild hot-pressing conditions of 500 °C for 1 h at 40 MPa. To ensure that these conditions enable sintering of the copper, we developed a synthesis route for the preparation of Cu nanoparticles (NPs) based on the reduction of a common copper salt in aqueous solution in the presence of a size control agent. Upon hot pressing these nanoparticles at 500 °C, we are able to achieve 92-93% of the theoretical density of copper. The resulting materials exhibit a CTE which can be tuned between the value of pure copper (16.5 ppm/°C) and less than 1 ppm/°C. Thus, by adjusting the relative amount of the two components, the properties of the composite can be designed so that a material with high electrical conductivity and a CTE that matches the relatively low CTE values of semiconductor or thermoelectric materials can be achieved. This unique combination of electrical and thermal properties enables these Cu-based metal-matrix composites to be used as electrical contacts to a variety of semiconductor and thermoelectric devices which offer stable operation under thermal cycling conditions.


Assuntos
Cobre/química , Nanopartículas Metálicas/química , Condutividade Térmica , Termodinâmica , Tamanho da Partícula , Propriedades de Superfície , Temperatura
12.
Hu Li Za Zhi ; 58(3): 80-6, 2011 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-21678257

RESUMO

Public health nurses are the largest manpower component in community-based psychiatric care in Taiwan. However, controversies related to primary responsibility for such have erupted and must be addressed in order to ensure patients receive the most appropriate care and healthcare professionals are adequately trained and supported. This article used the STEP (social-technological-economical-political assessment) method to assess the macro-level contextual changes that have affected healthcare centers and public health nurses providing community psychiatric care as well as their role function and development. This study recommends several policy changes based on findings.


Assuntos
Serviços Comunitários de Saúde Mental , Enfermagem em Saúde Pública , Serviços Comunitários de Saúde Mental/economia , Humanos , Política , Taiwan
13.
J Am Chem Soc ; 130(50): 16908-13, 2008 Dec 17.
Artigo em Inglês | MEDLINE | ID: mdl-19053479

RESUMO

We report an effective method to fabricate two-dimensional (2D) periodic oxide nanopatterns using S-layer proteins as a template. Specifically, S-layer proteins with a unit cell dimension of 20 nm were reassembled on silicon substrate to form 2D arrays with ordered pores of nearly identical sizes (9 nm). Octadecyltrichlorosilane (ODTS) was utilized to selectively react with the S-layer proteins, but not the Si surface exposed through the pores defined by the proteins. Because of the different surface functional groups on the ODTS-modified S-layer proteins and Si surface, area-selective atomic layer deposition of metal oxide-based high-k materials, such as hafnium oxide, in the pores was achieved. The periodic metal oxide nanopatterns were generated on Si substrate after selective removal of the ODTS-modified S-layer proteins. These nanopatterns of high-k materials are expected to facilitate further downscaling of logic and memory nanoelectronic devices.


Assuntos
Proteínas de Bactérias/química , Desoxirribonucleases/química , Nanoestruturas/química , Óxidos/química , Proteínas de Bactérias/genética , Proteínas de Bactérias/metabolismo , Proteínas de Bactérias/ultraestrutura , Desoxirribonucleases/genética , Desoxirribonucleases/metabolismo , Desoxirribonucleases/ultraestrutura , Microscopia de Força Atômica , Nanoestruturas/ultraestrutura , Silício/química , Espectrofotometria , Espectroscopia de Infravermelho com Transformada de Fourier , Propriedades de Superfície
14.
Arch Psychiatr Nurs ; 22(5): 266-76, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18809119

RESUMO

Community care has been a paradigm shift for psychiatric treatment worldwide; however, it has not been successfully implemented in many developing countries, including Taiwan. This qualitative study aimed to explore the Taiwanese mentally ill persons' difficulties living in the community. Social disadvantages and illness adaptation were recognized as two domains of difficulties encountered by Taiwanese mentally ill patients living in the community, while six themes were identified: getting a "shameful" illness, unmet needs for community care, being overcome by a distorted world, denying the illness, living with the illness, and adapting to changed level of functioning. Related cultural issues were also discussed.


Assuntos
Adaptação Psicológica , Atitude Frente a Saúde/etnologia , Transtornos Mentais/etnologia , Pessoas Mentalmente Doentes/psicologia , Atividades Cotidianas/psicologia , Adolescente , Adulto , Idoso , Serviços Comunitários de Saúde Mental/organização & administração , Desinstitucionalização , Negação em Psicologia , Países em Desenvolvimento , Família/etnologia , Feminino , Grupos Focais , Necessidades e Demandas de Serviços de Saúde , Humanos , Masculino , Transtornos Mentais/prevenção & controle , Pessoa de Meia-Idade , Pesquisa Metodológica em Enfermagem , Enfermagem Psiquiátrica , Pesquisa Qualitativa , Vergonha , Comportamento Social , Estereotipagem , Inquéritos e Questionários , Taiwan
15.
Nat Mater ; 4(3): 220-4, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15696172

RESUMO

Sol-gel immobilization of soluble proteins has proven to be a viable method for stabilizing a wide variety of proteins in transparent inorganic matrices. The encapsulation of membrane-bound proteins has received much less attention, although work in this area suggests potential opportunities in microarray technology and high-throughput drug screening. The present paper describes a liposome/sol-gel architecture in which the liposome provides membrane structure and protein orientation to two transmembrane proteins, bacteriorhodopsin (bR) and F(0)F(1)-ATP synthase; the sol-gel encapsulation converts the liposomal solution into a robust material without compromising the intrinsic activity of the incorporated proteins. Here we report on two different proteoliposome-doped gels (proteogels) whose properties are determined by the transmembrane proteins. Proteogels containing bR proteoliposomes exhibit a stable proton gradient when irradiated with visible light, whereas proteogels containing proteoliposomes with both bR and F(0)F(1)-ATP synthase couple the photo-induced proton gradient to the production of ATP. These results demonstrate that materials based on the liposome/sol-gel architecture are able to harness the properties of transmembrane proteins and enable a variety of applications, from power generation and energy storage to the powering of molecular motors, and represent a new technology for performing complex chemical synthesis in a solid-state matrix.


Assuntos
Trifosfato de Adenosina/síntese química , Proteínas de Bactérias/química , Bacteriorodopsinas/química , Lipossomos/química , Prótons , Dióxido de Silício/química , ATPases Bacterianas Próton-Translocadoras
16.
Methods Mol Biol ; 300: 53-79, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15657479

RESUMO

The sol-gel process is a chemical technique for immobilizing biomolecules in an inorganic, transparent matrix. The dopant biomolecules reside in an interconnected mesoporous network and become part of the nanostructured architecture of the entire material. In this chapter, we review the sol-gel immobilization approach and discuss how it leads to the stabilization of a number of proteins against aggressive chemical and thermal environments. We also review the sensor applications of this material that result from having analyte molecules diffuse through the matrix and reach the immobilized biomolecule.


Assuntos
Nanotecnologia , Técnicas Biossensoriais , Dicroísmo Circular , Creatina Quinase/química , Estabilidade Enzimática/fisiologia , Vidro/química , Temperatura Alta , Imunoensaio , Fatores de Tempo
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