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Zhongguo Zhen Jiu ; 40(4): 352-6, 2020 Apr 12.
Artigo em Chinês | MEDLINE | ID: mdl-32275360


OBJECTIVE: To observe the effect of electronic moxibustion on memory function in the patients with amnestic mild cognitive impairment (aMCI). METHODS: A total of 59 aMCI patients were randomized into an electronic moxibustion group (30 cases) and a placebo moxibustion group (29 cases). In the electronic moxibustion group, the electronic moxibustion was applied to Baihui (GV 20), Dazhui (GV 14), Mingmen (GV 4) and Taixi (KI 3), 45 ℃ in temperature, 20 min each time. The treatment was given once a day, 5 times a week. The treatment for 4 weeks was as one course and 2 courses were required totally. In the placebo moxibustion group, the moxa-free patch was used, 38 ℃ in temperature. The acupoint selection and the treatment frequency were same as the electronic moxibustion group. Before and after treatment, Rivermead behavior memory test (RBMT) was adopted to evaluate the global memory function of the patients in the two groups and the N-back task test was adopted to evaluate working memory function separately. Additionally, the mini-mental state examination (MMSE) and its immediate memory, Montreal cognitive assessment (MoCA) and its delay recall were adopted to evaluate the global cognitive function and memory function. RESULTS: In the electronic moxibustion group, after treatment, RBMT score, N-back accuracy rates, MMSE and MoCA scores and the scores of immediate memory and delay recall were improved significantly as compared with those before treatment (P<0.01). In the placebo moxibustion group, the accuracy rates of 1-back and 2-back task and the scores of immediate memory and delay recall were improved obviously as compared with those before treatment (P<0.05, P<0.01). After treatment, the improvements of RBMT score, the accuracy rates of N-back task and MMSE and MoCA scores in the electronic moxibustion group were higher than those in the placebo moxibustion group (P<0.05). CONCLUSION: Electronic moxibustion improves memory function in the patients with amnestic mild cognitive impairment.

Amnésia/terapia , Disfunção Cognitiva/terapia , Memória , Moxibustão/métodos , Pontos de Acupuntura , Humanos , Testes de Estado Mental e Demência
Chemosphere ; 253: 126663, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32278914


In this study, a comparative investigation of palm bark and corncob (a well-investigated material) for enhancing nitrogen removal efficiency in partially saturated vertical constructed wetland (PSVCW) was performed to evaluate an effective and cost-effective supplementary carbon source. The characteristics of the released organic matter and the release processes were analyzed through optical property characterization and a first-order release-adsorption model, respectively, and the nitrogen removal performance was evaluated in a series of pilot-scale PSVCWs. Results showed that the amount of organic matter released per unit mass of corncob was larger than that released per unit mass of palm bark under the same pretreatment conditions (control, heat, and alkaline pretreatment). The organic matter released from corncob has a higher apparent molecular weight and a higher degree of aromatic condensation than those of the organic matter released from palm bark, whereas the organic matter released from palm bark has higher and more stable bioavailability. Moreover, palm bark showed a more significant improvement of release capacity with the heat and alkaline pretreatment methods. Pilot-scale studies revealed that PSVCW using palm bark as the supplementary carbon source has a longer replacement cycle and higher total nitrogen (TN) removal efficiency than that using corncob, indicating that palm bark can be considered an effective and inexpensive supplementary carbon source. This study provides initial guidance for the ongoing research on supplementary carbon sources for improving nitrogen removal efficiency in constructed wetlands.

Eliminação de Resíduos Líquidos/métodos , Áreas Alagadas , Adsorção , Carbono , Desnitrificação , Cinética , Nitrogênio , Projetos Piloto , Casca de Planta
Zhongguo Zhen Jiu ; 39(3): 299-302, 2019 Mar 12.
Artigo em Chinês | MEDLINE | ID: mdl-30942019


In the aspects of the acupoint prescription, acupuncture techniques and typical cases, the characteristics and experience of professor ZHANG Qing-ping in the clinical treatment of vascular dementia with acupuncture and moxibustion were introduced. Vascular dementia is treated on the base of etiology, focusing on the brain as the root cause, with the reinforcing and the promoting as the dominant principle of acupuncture. The treatment is emphasized on tonifying the kidney to fill up marrow, strengthening the spleen to nourish the brain and promoting the collateral circulation to improve the intelligence. Concerning to the general situation of the disease, regulating mind stressed in treatment. In clinical practice, Baihui (GV 20) is the chief acupoint to benefit the brain. Yuan-source points and the eight influential points are predominated to tonify the functions of zangfu organs and fill up vessels. Moxibustion is adopted to resolve the stagnation and promote circulation in meridian as well as regulate qi and blood circulation. Specially, the moxibustion technique for resolving the stagnation and promoting circulation in meridian achieves the satisfactory therapeutic effects in clinical treatment.

Terapia por Acupuntura , Demência Vascular , Meridianos , Moxibustão , Demência Vascular/terapia , Humanos
Cancer Med ; 8(6): 2840-2857, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31016890


BACKGROUND: To evaluate the significance and benefit of radiotherapy (RT) in young early-stage breast cancer patients according to different molecular subtypes. METHODS: We conducted a retrospective cohort study utilizing the Surveillance, Epidemiology, and End Results database with known hormone receptor (HoR) and human epidermal growth factor receptor 2 (HER2) status. Female patients aged 18-45, received RT treatment, and diagnosed with stage T1-3, N0-3, M0 primary breast cancer between 2010 and 2013 were identified. RESULTS: Of all the 23 148 included patients, 14 708 (63.54%), 3385 (14.62%), 1225 (5.29%), and 3830 (16.55%) were diagnosed with luminal-A (HoR + HER2-), luminal-B (HoR + HER2+), HER2-enriched (HoR-HER2+), and triple-negative (HoR-HER2-) breast cancer, respectively. RT was significantly correlated with improved overall survival (OS, HR: 0.295; 95% CI:0.138-0.63, P = 0.002) and breast cancer-specific survival (BCSS, HR: 0.328; 95% CI: 0.153-0.702, P = 0.004) in HER2-enriched patients. In addition, a significantly prolonged OS was also observed when RT was given to luminal-A (HR: 0.696; 95% CI: 0.538-0.902, P = 0.006) and luminal-B (HR: 0.385; 95% CI:0.199-0.744, P = 0.005) breast cancer patients compared to those without RT. Multivariable-adjusted analyses showed that HER2 was a significant favorable factor for RT benefit in breast cancer patients. CONCLUSIONS: RT could offer significant survival benefit in luminal-A, luminal-B, and especially HER2-enriched young early-stage breast cancer female patients. The results enabled clinicians to predict the benefits of RT and improve evidence-based treatment for breast cancer patients.