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1.
Community Dent Oral Epidemiol ; 45(6): 545-551, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28653758

RESUMO

OBJECTIVES: The aim of this case-control study was to evaluate the association between periodontitis and breast cancer in a sample of adult Brazilian women. METHODS: This was a hospital-based study, which included 67 cases and 134 controls (1:2). Women were selected consecutively between April, 2013 and June, 2015 among those attending the Department of Gynecology at the University Hospital of Santa Maria. Cases were selected among women diagnosed with breast cancer (ICD-10 C50), and controls were matched for age (±2 years), and smoking status (never, former and current smoker). Conditional logistic regression was used to model the association between periodontitis and breast cancer with and without adjustment for potential confounders. Four case definitions for periodontitis were used. RESULTS: Cases had significantly greater clinical attachment loss than controls (P=.04). After adjusting for important covariates, women diagnosed with periodontitis had two to three times higher odds of breast cancer than women without periodontitis depending on the case definition of periodontitis (P<.05). CONCLUSIONS: A significant association was observed between periodontitis and breast cancer.


Assuntos
Neoplasias da Mama/epidemiologia , Periodontite/epidemiologia , Brasil/epidemiologia , Estudos de Casos e Controles , Feminino , Humanos , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Fumar/epidemiologia
2.
J Endod ; 43(3): 370-376, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28231976

RESUMO

INTRODUCTION: The aim of this study was to perform a critical review of the literature that investigated the association between diabetes and apical periodontitis. METHODS: An electronic search was performed on PubMed/MEDLINE, LILACS, Scientific Electronic Library Online (Scielo), and Cochrane Collaboration databases. Human studies assessing the effect of diabetes in apical periodontitis development or in healing after root canal treatment were included. The outcome was apical periodontitis. RESULTS AND CONCLUSIONS: Nine articles were included. The results presented in the literature to date are still scarce and incipient, and the evidence for such an association is not yet conclusive. However, the published results trend to converge on a positive association between diabetes and a larger number of periapical lesions.


Assuntos
Complicações do Diabetes , Periodontite Periapical/etiologia , Humanos
3.
Periodontia ; 27(1): 34-39, 2017.
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-836947

RESUMO

Introdução: Estudos sugerem a relação entre doença periodontal e condições sistêmicas, dentre elas o câncer. A plausibilidade biológica desta possível associação é o aumento de marcadores inflamatórios na corrente sanguínea devido a uma infecção crônica. Objetivo: Revisar a literatura sobre a associação entre a condição periodontal e câncer em sítios específicos, bem como analisar a influência de fatores de risco e confundimento nessa inter-relação. Materiais e Métodos: A busca da literatura foi realizada na base de dados PubMed, utilizando as palavras-chave: "periodontal diseases"; "tooth loss"; "inflammation"; "risk factors" e "cancer". A busca foi limitada a artigos a partir do ano 2000, com delineamento caso-controle e coorte incluindo seres humanos. Resultados: Alguns estudos demonstraram associações estatisticamente significantes entre avaliações das medidas periodontais e/ ou a perda dentária, principalmente para o câncer oral e do trato gastrointestinal superior, além do câncer de mama, hematológico, de pâncreas e de pulmão, em diferentes populações. Essas associações persistem em alguns estudos mesmo após o ajuste para fatores de risco como o fumo, a condição socioeconômica e o consumo de álcool. Conclusões: Esta revisão de literatura sugere que o quadro inflamatório associado às doenças periodontais tem um possível papel no processo de carcinogênese, independente de outros fatores de risco associados. Porém, nenhum estudo apresentou resultados conclusivos sobre influência do quadro inflamatório periodontal na carcinogênese.(AU)


Introduction: Studies suggest the relationship between periodontal disease and systemic conditions, among them cancer. The biological plausibility of this possible association is the increase in inflammatory markers in the bloodstream due to a chronic infection. Aim: To review the literature about the association between periodontal status and cancer at specific sites and to analyze the influence of risk factors and confounding in this interrelationship. Methodology: The literature search was conducted in PubMed database using the keywords: "periodontal diseases"; "tooth loss"; "inflammation"; "risk factors" and "cancer". The search was limited to articles from 2000, with case-control and cohort including humans. Results: Some studies have shown statistically significant association between periodontal evaluation of measures and/ or tooth loss, especially for oral and upper gastrointestinal tract cancer, and breast cancer, hematologic, pancreas and lung, in different populations. These associations persist in some studies even after adjusting for risk factors such as smoking, socioeconomic status and alcohol consumption. Conclusion: This literature review suggests that the inflammatory process associated with periodontal disease have a possible role in the carcinogenesis process, independent of other risk factors. However, no study showed conclusive results about the influence of periodontal inflammatory process in carcinogenesis. (AU)


Assuntos
Neoplasias , Doenças Periodontais , Fatores de Risco , Perda de Dente
4.
J Clin Periodontol ; 43(3): 250-60, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26790108

RESUMO

BACKGROUND: Adjuvant antibiotics have been suggested to improve periodontal therapy in diabetic subjects. AIM: The aim of this study was to systematically review randomized clinical trials assessing systemic antimicrobial use adjuvant to scaling and root planing (SRP) versus SRP alone in diabetic subjects. MATERIAL AND METHODS: The PubMed, Cochrane Central Register of Controlled Trials, EMBASE, TRIP, Web of Science and LILACS databases and the grey literature were searched through May 2015. Of 2534 potentially eligible studies, 13 were included in the systematic review. Weighted mean differences (WMDs) in probing depth (PD) reduction and clinical attachment level (CAL) gain (primary outcomes), and plaque index (PI) and bleeding on probing (BOP) reductions, were estimated using a random effect model. RESULTS: The WMD in PD reduction [-0.15 mm, n = 11, p = 0.001, 95% confidence interval (CI) -0.24, -0.06] favoured antibiotic use. WMDs in CAL gain, PI and BOP reductions (-0.14 mm, n = 9, p = 0.11, 95% CI -0.32, 0.03; 4.01%, n = 7, p = 0.05, 95% CI -0.04, 8.07; and -1.91%, n = 7, p = 0.39, 95% CI -6.32, 2.51 respectively) did not favour adjunctive antibiotic use. CONCLUSION: Adjunctive therapy may improve the efficacy of SRP in reducing PD in diabetic subjects.


Assuntos
Anti-Infecciosos/uso terapêutico , Adulto , Idoso , Antibacterianos/uso terapêutico , Raspagem Dentária , Diabetes Mellitus/tratamento farmacológico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Perda da Inserção Periodontal/tratamento farmacológico , Índice Periodontal , Bolsa Periodontal/tratamento farmacológico , Aplainamento Radicular
5.
Rev. odontol. UNESP (Online) ; 44(3): 152-156, May-Jun/2015. tab, graf
Artigo em Inglês | LILACS-Express | ID: lil-749885

RESUMO

Introduction Smoking is a risk factor for prevalence, severity and progression of periodontal disease and appears to suppress marginal periodontium inflammatory response. Purpose To correlate Visible Plaque Index (VPI) and Gingival Bleeding Index (GBI) in smokers and never-smokers, as well as GBI and bleeding on probing (BOP ) in these groups. Material and method We used baseline data of one quasi-experimental study in which 11 smokers and 14 subjects who never smoked were submitted to clinical periodontal examinations between September 2010 and October 2011. Result The correlation between VPI and GBI was positive for both groups, it was strong and statistically significant in subjects who had never smoked and moderate in smokers. Regarding GBI and BOP correlations were moderate for smokers and weaker for individuals who had never smoked. Conclusion Smokers have lower strength correlation between VPI and GBI compared to individuals who had never smoked resulting in a less pronounced marginal gingival bleeding. .


Introdução O hábito de fumar é um fator de risco importante na prevalência, progressão e gravidade das doenças periodontais e parece suprimir a resposta inflamatória marginal no periodonto. Objetivo Correlacionar Índice de Placa visível (IPV) e Índice de Sangramento Gengival (ISG) em fumantes e indivíduos que nunca fumaram, bem como correlacionar ISG e o sangramento à sondagem (SS) nesses dois grupos. Material e método Foram utilizados dados de baseline de um estudo quasi-experimental, no qual 11 pacientes fumantes e 14 indivíduos que nunca fumaram foram submetidos a exames clínicos periodontais no período de setembro de 2010 e outubro de 2011. Resultado A correlação entre IPV e ISG foi positiva para ambos os grupos, sendo forte e estatisticamente significante nos indivíduos que nunca fumaram e moderada nos fumantes. Com relação ao ISG e SS houve moderada correlação para os fumantes e fraca para os indivíduos que nunca fumaram. Conclusão Fumantes apresentam uma correlação entre IPV e ISG de menor força em relação aos indivíduos que nunca fumaram resultando em um sangramento gengival marginal menos pronunciado. .

6.
J Appl Oral Sci ; 22(5): 450-8, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25466478

RESUMO

OBJECTIVE: Considering that periodontal ligament simulation may influence the stress distribution over teeth restored with intraradicular retainers, this study aimed to assess the combined effect of mechanical cycling and periodontal ligament simulation on both the bond strength between fiber posts and root dentin and the fracture resistance of teeth restored using glass fiber posts. MATERIAL AND METHODS: Ninety roots were randomly distributed into 3 groups (n=10) (C-MC: control; P-MC: polyether; AS-MC: addition silicone) to test bond strength and 6 groups (n=10) (C: control; P: polyether; AS: addition silicone, without mechanical cycling, and C-MC, P-MC and AS-MC with mechanical cycling) to test fracture strength, according to the material used to simulate the periodontal ligament. For the bond strength test, fiber posts were cemented, cores were built, mechanical cycling was applied (2×10(6) cycles, 88 N, 2.2 Hz, and 45º incline), and the teeth cut into 3 slices (2 mm), which were then subjected to the push-out test at 1 mm/min. For the fracture strength test, fiber posts were cemented, cores were built, and half of the groups received mechanical cycling, followed by the compressive strength (45° to the long axis and 1 mm/min) performed on all groups. RESULTS: Periodontal ligament simulation did not affect the bond strength (p=0.244) between post and dentin. Simulation of periodontal ligament (p=0.153) and application of mechanical cycling (p=0.97) did not affect fracture resistance. CONCLUSIONS: The materials used to simulate the periodontal ligament did not affect fracture or bond strength, therefore periodontal ligament simulation using the tested materials could be considered optional in the conditions of the study.


Assuntos
Colagem Dentária/métodos , Ligamento Periodontal , Técnica para Retentor Intrarradicular , Fraturas dos Dentes , Animais , Bovinos , Resinas Compostas/química , Força Compressiva , Falha de Restauração Dentária , Análise do Estresse Dentário , Vidro/química , Teste de Materiais , Microscopia Eletrônica de Varredura , Distribuição Aleatória , Reprodutibilidade dos Testes , Estresse Mecânico , Propriedades de Superfície , Resistência à Tração
7.
J. appl. oral sci ; 22(5): 450-458, Sep-Oct/2014. tab, graf
Artigo em Inglês | LILACS | ID: lil-729851

RESUMO

Objective: Considering that periodontal ligament simulation may influence the stress distribution over teeth restored with intraradicular retainers, this study aimed to assess the combined effect of mechanical cycling and periodontal ligament simulation on both the bond strength between fiber posts and root dentin and the fracture resistance of teeth restored using glass fiber posts. Material and Methods: Ninety roots were randomly distributed into 3 groups (n=10) (C-MC: control; P-MC: polyether; AS-MC: addition silicone) to test bond strength and 6 groups (n=10) (C: control; P: polyether; AS: addition silicone, without mechanical cycling, and C-MC, P-MC and AS-MC with mechanical cycling) to test fracture strength, according to the material used to simulate the periodontal ligament. For the bond strength test, fiber posts were cemented, cores were built, mechanical cycling was applied (2×106 cycles, 88 N, 2.2 Hz, and 45º incline), and the teeth cut into 3 slices (2 mm), which were then subjected to the push-out test at 1 mm/min. For the fracture strength test, fiber posts were cemented, cores were built, and half of the groups received mechanical cycling, followed by the compressive strength (45° to the long axis and 1 mm/min) performed on all groups. Results: Periodontal ligament simulation did not affect the bond strength (p=0.244) between post and dentin. Simulation of periodontal ligament (p=0.153) and application of mechanical cycling (p=0.97) did not affect fracture resistance. Conclusions: The materials used to simulate the periodontal ligament did not affect fracture or bond strength, therefore periodontal ligament simulation using the tested materials could be considered optional in the conditions of the study. .


Assuntos
Animais , Bovinos , Colagem Dentária/métodos , Ligamento Periodontal , Técnica para Retentor Intrarradicular , Fraturas dos Dentes , Força Compressiva , Resinas Compostas/química , Falha de Restauração Dentária , Análise do Estresse Dentário , Vidro/química , Teste de Materiais , Microscopia Eletrônica de Varredura , Distribuição Aleatória , Reprodutibilidade dos Testes , Estresse Mecânico , Propriedades de Superfície , Resistência à Tração
8.
Periodontia ; 23(2): 52-57, 2013. ilus, tab, graf
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-707605

RESUMO

A doença periodontal está entre as principais doenças que podem afetar a cavidade bucal e é uma das causas mais expressivas de perda dentária no mundo. Sabe-se que, na maioria das pessoas, com medidas preventivas e terapêuticas adequadas há a possibilidade de manutenção dos dentes na cavidade bucal em conforto e função por toda a vida. O objetivo do presente estudo foi avaliar o nível de ligamento periodontal remanescente em dentes extraídos, recolhidos no gabinete odontológico da Secretaria Municipal de Rosário do Sul-RS. Consiste em um estudo piloto, realizado por meio de coleta de dentes extraídos no período de um mês. Fichas contendo gênero, idade e motivo da extração foram preenchidas pelo dentista e recolhidas juntamente com os dentes. Trinta e oito dentes foram corados e avaliados microscopicamente para a verificação de quanto apresentavam de inserção periodontal. A média da área de ligamento periodontal residual foi de 53,83%. A maior parte dos dentes apresentou coroa íntegra ou pequena destruição coronária e doença periodontal foram a principal razão encontrada para as exodontias. Pode ser concluído que uma quantidade significativa de ligamento periodontal residual foi observada. Porém, por ter sido este um estudo piloto, outros estudos são necessários para que os resultados sirvam de base para o planejamento de tratamento periodontal no atendimento público de saúde.


Periodontal disease is among the major diseases that can affect the oral cavity and it is one of the most significant causes of tooth loss in the world. It is known that with appropriate preventive and therapeutic measures is possible to maintain the teeth in the oral cavity in comfort and function throughout life for most people. The aim of this study was to evaluate the level of remaining periodontal ligament in extracted teeth, collected in the dental office of Secretaria Municipal de Saúde de Rosário do Sul – RS. It consists of a pilot study, conducted through the collection of extracted teeth in a month. Records containing gender, age and reason for extraction were filled by the dentist and collected together with the teeth. Thirtyeight teeth were stained and evaluated microscopically for verification of how much periodontal attachment they had. The mean residual area of the periodontal ligament was 53,83%. Most of the teeth was fully crown or small coronal destruction and periodontal disease is the main reason found for extractions. It can be concluded that a significant amount of residual periodontal ligament was observed. However, because it was a pilot study, further studies are needed to make results as a basis for planning periodontal treatment in public health care.


Assuntos
Humanos , Extração Dentária , Perda de Dente
9.
Clín. int. j. braz. dent ; 7(1): 98-105, jan.-mar.2011. ilus, tab
Artigo em Português | LILACS | ID: lil-757828

RESUMO

A cárie dentária é uma doença multifatorial, mediada por um biofilme oportunista que, para se manifestar clinicamente, necessita da interação de vários fatores em condições críticas. Atualmente, sua lenta evolução propicia manejo clínico mais voltado para a detecção de lesões incipientes. Assim, torna-se possível controlar a progressão da doença antes que ela atinja uma fase irreversível. Este trabalho relata um caso clínico de diagnóstico e tratamento de lesões cariosas incipientes em dentes anteriores e seu manejo clínico e discute as evidências disponíveis...


Dental caries is a multifactorial disease produced by an opportunistic biofilm that needs the interaction of several factors at specific conditions to occur. Currently, the slow progression trend provides allows for the clinical management more focused on the detection of incipient lesions. This makes possible to control the progression of the disease before reaching an irreversible stage. This article is a case report of the diagnostic and treatment of incipient carious lesion in permanent incisors discussing the available evidence...


Assuntos
Humanos , Feminino , Criança , Assistência Odontológica para Crianças , Cárie Dentária , Fluorose Dentária , Higiene Bucal
10.
Clín. int. j. braz. dent ; 6(4): 458-463, out.-dez.2010. ilus
Artigo em Português | LILACS | ID: lil-757819

RESUMO

Com o uso disseminado dos dentifrícios fluoretados, tem-se observado aumento na prevalência da fluorose dentária, e são mais comuns casos de pacientes que buscam solução estética para manchamentos do esmalte dentário. Estudos recentes mostram que a percepção da perda estética causada pela fluorose acorre apenas nos graus mais severos da patologia. Este artigo relata o caso de uma jovem de 22 anos que buscou solução para manchas de fluorose de grau quatro de Thylstrup e Fejerskov, o que foi realizado por meio de uma técnica simplificada de erosão-abrasão (microabrasão)...


The widespread use of fluoride-containing dentifrices led to an increased prevalence of dental fluorosis. Patients seeking for esthetic solutions for enamel staining are more frequent. Recent studies show that the perception of esthetic impairment caused by fluorosis occur only in patients with most severe cases. This article is a case report of a 22 year-old female that was seeking for the solution for her severely stained enamel (dental fluorosis, Thylstrup & Fejerskov scale, TF-4 degree). The case was adequately treated with a simplified microabrasion technique...


Assuntos
Humanos , Feminino , Adulto Jovem , Microabrasão do Esmalte , Estética Dentária , Fluoretos , Fluorose Dentária
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