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1.
Trends Psychiatry Psychother ; 41(3): 268-275, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31644693

RESUMO

INTRODUCTION: Instruments aimed to investigate general aspects of quality of life are scarce in the literature. Flanagan's Quality of Life Scale (QoLS) is an alternative instrument which provides a more comprehensive evaluation of quality of life in different contexts. OBJECTIVE: To investigate some psychometric properties of the QoLS and discuss the measurement of quality of life using this scale in heterogeneous and large populations. METHODS: The QoLS comprises 16 items divided into five dimensions. Responses were measured using a 7-point rating scale. Data were collected from a stratified sample of primary health care users in the municipality of Ribeirão Preto, state of São Paulo, Brazil. Polychoric correlation matrix and exploratory and confirmatory factor analyses were performed. RESULTS: A total of 1,054 primary health care users in 12 health care facilities were interviewed: 79.7% female; mean age = 36.97 years (standard deviation = 15.1). Moderate to low correlation coefficients were observed between almost all pairs of QoLS items. Items 7 and 9 as well as items 14 and 15 were the pairs presenting the highest correlation coefficient. The original structure of the QoLS, with five dimensions, showed adequate psychometric properties regarding the data collected. The inclusion of a single item on life satisfaction was proposed. CONCLUSION: The original structure of the QoLS was validated and found to be reliable when applied to primary health care users. A new general item was suggested for future studies to improve the interpretations and associations regarding general aspects of quality of life in large and heterogeneous populations.

2.
Rev Saude Publica ; 53: 55, 2019 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-31432912

RESUMO

OBJECTIVE: To examine the effect of seasonality on femoral fracture incidence among people residing in the state of São Paulo, Brazil. METHODS: Ecological study based on a consecutive series of 216,348 reports of hospital admissions caused by femoral fractures. A Bayesian statistical model was used for time series analysis, considering the monthly average number of events of femoral fractures per day as a dependent variable. RESULTS: Among the female population, significant seasonal effects were observed only for older women, aged 60 years or more. Among younger men (aged less than 20 years) there is not a clear seasonal effect, but among the other age groups there seems to exist a higher number of cases of femoral fractures during the coldest months of the year. CONCLUSIONS: In general, more cases of fractures occur during the coldest months of the year; however, men and women have different patterns of incidence according to each age group.


Assuntos
Fraturas do Fêmur/epidemiologia , Adolescente , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Teorema de Bayes , Brasil/epidemiologia , Criança , Pré-Escolar , Feminino , Humanos , Incidência , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Estações do Ano , Fatores Sexuais , Adulto Jovem
3.
Rev Soc Bras Med Trop ; 52: e20180532, 2019 Jul 18.
Artigo em Inglês | MEDLINE | ID: mdl-31340359

RESUMO

INTRODUCTION: Although congenital syphilis is preventable, its incidence has increased in Brazil. METHODS: In this ecological study, a Bayesian spatio-temporal model was used to estimate the attributable fraction of congenital syphilis cases due to the lack of prenatal care recorded between 2010 and 2015 in the state of São Paulo, Southeast Brazil. RESULTS: For the year 2016, it was estimated that between 79.4% and 95.3% of the congenital syphilis cases among women who did not have prenatal care could have been prevented. CONCLUSIONS: A significant proportion of congenital syphilis cases can be prevented if prenatal care coverage is expanded.


Assuntos
Transmissão Vertical de Doença Infecciosa/estatística & dados numéricos , Complicações Infecciosas na Gravidez/epidemiologia , Cuidado Pré-Natal , Sífilis Congênita/epidemiologia , Teorema de Bayes , Brasil/epidemiologia , Notificação de Doenças , Feminino , Sistemas de Informação em Saúde , Humanos , Incidência , Gravidez , Características de Residência
4.
J Ethnopharmacol ; 242: 112060, 2019 Oct 05.
Artigo em Inglês | MEDLINE | ID: mdl-31279865

RESUMO

ETHNOPHARMACOLOGICAL RELEVANCE: Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) is a plant traditionally used as medicine for anxiety symptoms. This activity was confirmed in preclinical studies. However, its efficacy was never studied in human clinical trials. AIM OF THE STUDY: We aimed to test the hypothesis that the herbal medicine of A. polystachya is superior to placebo for the treatment of anxiety-related symptoms in adults after 8 weeks. PATIENTS AND METHODS: This was a randomized, double-blind, placebo-controlled, phase-2 clinical trial. Fifty-four adults with self-reported anxiety symptoms were randomly allocated to receive either capsules containing A. polystachya powdered leaves (300 mg, twice a day) or placebo (maltodextrin), for 8 weeks. The intensity of anxiety symptoms was assessed by the Hamilton Anxiety Ranking Scale (HAM-A) at baseline and after 2, 4 and 8 weeks. All analyses were adjusted for physical activity (assessed by the International Physical Activity Questionnaire [IPAQ], short version) and gender. RESULTS: We confirmed the presence of acteoside (chromatographic analysis) and carvone and limonene (gas chromatography) as major constituents in our plant material. Only patients that received A. polystachya experienced a significant decrease in their HAM-A scores, with none or mild side-effects. CONCLUSION: Administration of powdered leaves of A. polystachya, rich in acteoside, carvone and limonene, to adults with anxiety symptoms was significantly superior to placebo in decreasing HAM-A scores after 8 weeks. This finding confirms the ethnopharmacological use of this plant for anxiety symptoms.

5.
Cad. saúde colet., (Rio J.) ; 27(2): 146-157, abr.-jun. 2019. tab
Artigo em Inglês | LILACS-Express | ID: biblio-1011742

RESUMO

Abstract Background A number of studies have been reported on the role of religiosity in health beliefs and behaviors. Objective The objective of this cross-sectional study is to examine the association between religious involvement and patterns of alcohol consumption in a large representative sample of users of primary healthcare facilities in Ribeirão Preto, Southeast Brazil. Method Data were collected through personal interviews. Religiosity was measured using the Duke University Religion Index (DUREL) and the alcohol consumption was measured using the Alcohol Use Disorders Identification Test (AUDIT) questionnaire. Multinomial logistic regression models were used to evaluate the associations between the participant characteristics, the AUDIT risk levels, and the drinking groups. Results The sample was composed of 841 women with a mean age of 39.5 years old and 214 men with a mean age of 45.1 years old. A significant relationship between patterns of alcohol consumption and the multiple dimensions of religiosity was detected, such as religious affiliation, religious practices, self-perception of the level of religiosity and the ORA, NORA and IR components of DUREL. Lower levels of drinking risk were detected among religious individuals and among those who practice their religions compared to individuals who have no religion and/or non-practicing individuals, respectively. Conclusion A lifestyle motivated by religious concerns is associated with alcohol use habits among the Brazilian users of the public healthcare facilities.


Resumo Introdução Vários estudos têm mostrado o papel da religiosidade nas crenças e comportamentos em saúde. Objetivo O objetivo deste estudo transversal é examinar a associação entre envolvimento religioso e padrões de consumo de álcool em uma amostra representativa de usuários de unidades de atenção primária à saúde de Ribeirão Preto, Brasil. Método Os dados foram obtidos por entrevistas pessoais. A religiosidade foi mensurada usando o Duke University Religion Index (DUREL) e o consumo de álcool foi mensurado pelo Alcohol Use Disorders Identification Test (AUDIT). Modelos de regressão logística multinomiais foram usados para avaliar as associações entre as características dos participantes, os níveis do AUDIT e os grupos de consumo de álcool. Resultados A amostra foi composta por 841 mulheres com idade média de 39,5 anos e 214 homens com média de idade de 45,1 anos. Foram evidenciadas associações significativas entre padrões de consumo de álcool e as múltiplas dimensões da religiosidade, como afiliação religiosa, práticas religiosas, autopercepção do nível de religiosidade e os componentes do DUREL. Baixos níveis de ingestão de álcool foram detectados entre indivíduos religiosos e entre aqueles que praticam sua religião, comparados com aqueles que não possuem uma religião e/ou não praticam uma religião, respectivamente. Conclusão Um estilo de vida motivado por interesses religiosos é associado com os hábitos de uso de álcool entre os usuários de unidades de atenção primária à saúde.

6.
Physiother Theory Pract ; : 1-8, 2019 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-31046526

RESUMO

This study aimed to verify whether there are differences in foot type, physical function, and performance between children and adolescents with Charcot-Marie-Tooth disease (CMT) and their healthy counterparts, and whether an interval of 6 months, from the initial assessment, reveals any significant changes on physical performance and other specific physical measures of the lower limbs. SUBJECTS AND METHODS: Participants between 6 and 17 years of age, with CMT (CMT group n = 40), were compared to healthy participants (Control group, n = 49). Twenty participants with CMT completed the follow-up. We collected anthropometric, goniometric (ankle and knee), and dynamometric (inversion, eversion, plantar flexors, dorsiflexors, knee, hip extensors) measures, agonist/antagonist ratios, feet alignment (Foot Posture Index - FPI), muscle power (Long Jump), Pediatric Balance Scale (PBS), and 10-meter walk test (10MWT). RESULTS: Compared to Control, CMT showed reduced passive range of motion (ROM), weakness in all evaluated muscles, increased agonist/antagonist ratios, predominance of varus and lower performance (PBS and Long Jump). After 6 months, CMT measures did not change. CONCLUSION: The cross-sectional analysis showed reduced ROM, strength, power, and distal muscle imbalance, as well as secondary limitations (PBS and 10MWT) in children and adolescents with CMT. These biomechanical and functional alterations did not change at the 6-month follow-up.

7.
Rev Soc Bras Med Trop ; 52: e20180020, 2019 Apr 11.
Artigo em Inglês | MEDLINE | ID: mdl-30994791

RESUMO

INTRODUCTION: AIDS remains a major public health concern in Brazil. METHODS: This study investigated spatiotemporal patterns of reported AIDS cases among adults in São Paulo between 2000 and 2016, and their associations with human development index. RESULTS: In the early 20th century, the more developed administrative districts (ADs) indicated higher AIDS incidences among men. From the 2010s, ADs with lower development indicate higher rates of the disease among women. CONCLUSIONS: The results are useful to support the planning of actions aimed at controlling the incidence and transmission of AIDS in certain areas, based on diversification by gender and risk populations.


Assuntos
Síndrome de Imunodeficiência Adquirida/epidemiologia , Adulto , Brasil/epidemiologia , Notificação de Doenças , Feminino , Humanos , Incidência , Masculino , Modelos Teóricos , Fatores de Risco , Fatores Socioeconômicos , Análise Espaço-Temporal
8.
Codas ; 31(2): e20180174, 2019 Apr 01.
Artigo em Português, Inglês | MEDLINE | ID: mdl-30942292

RESUMO

PURPOSE: Investigating the perception and self-reported behavior of speech-language therapist about ethical and legal aspects related to the use of images of patients in social networks, comparing such findings with sociodemographic data. METHODS: An online questionnaire with 13 questions was the instrument used to collect data related to the demographic data of the participants and to the perception of speech-language therapists. The questionnaire was available on the Google Forms platform e was answered by 765 participants. RESULTS: Most participants agreed that the Code of Ethics of Speech-Language Pathology gives information about the use of images in social networks (67.98%), that the publication of photos and / or videos of patients in social networks without authorization by written is an ethical infraction (93.33%) and that the image´s rights is guaranteed by the Brazilian Constitution (89.94%). 18.56% of speech-language pathologists stated that they had never used the Code of Ethics in Speech-Language Pathology. Concerning the exhibition of images in social networks, 5.1% stated that they had shown on their social networks photographs and / or videos without authorization, and 21.18% did so with only verbal authorization. Almost all participants (95.16%) mentioned having seen photographs or videos of patients on virtual social networks posted by speech-language therapist. CONCLUSION: It was possible to verify the relevance of the results obtained and the impact of the research to encourage reflection on the subject.


Assuntos
Atitude do Pessoal de Saúde , Ética Profissional , Redes Sociais Online , Percepção , Patologia da Fala e Linguagem/ética , Adulto , Idoso , Brasil , Humanos , Pessoa de Meia-Idade , Fatores Socioeconômicos , Patologia da Fala e Linguagem/estatística & dados numéricos , Inquéritos e Questionários , Adulto Jovem
9.
Pediatr Phys Ther ; 31(2): 185-190, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30907836

RESUMO

PURPOSE: This study aimed to develop a prediction model for peak oxygen uptake ((Equation is included in full-text article.)O2peak) in children with spina bifida (SB), considering peak workload (Wpeak), peak heart rate, age, sex, anthropometric measures, walking level, physical activity level, and level of the lesion. METHODS: Data of 26 participants with SB performing a graded arm crank test were used to develop the prediction model. An unrelated data set of participants with SB was used for validation. RESULTS: The following equation was developed to predict (Equation is included in full-text article.)O2peak of participants with SB: (Equation is included in full-text article.)O2peak (mL/min) = 194+18 × Wpeak - 110 × sex (adjusted R(2) = 0.933, SEE = 96 mL/min). Bland-Altman analysis showed a nonsignificant mean difference between the measured and predicted values of (Equation is included in full-text article.)O2peak (-0.09 L/min) and limits of agreement of -0.4036 and 0.2236 L/min. CONCLUSIONS: The prediction model shows promising results; however, further validation using the same protocol is warranted before implementation in clinical practice.


Assuntos
Ergometria/métodos , Ergometria/normas , Consumo de Oxigênio/fisiologia , Disrafismo Espinal/fisiopatologia , Adolescente , Fatores Etários , Braço , Pesos e Medidas Corporais , Criança , Exercício , Teste de Esforço/métodos , Teste de Esforço/normas , Tolerância ao Exercício , Feminino , Frequência Cardíaca/fisiologia , Humanos , Masculino , Reprodutibilidade dos Testes , Fatores Sexuais , Carga de Trabalho
10.
Homeopathy ; 108(2): 102-107, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30736083

RESUMO

BACKGROUND: Hot flashes are common in women during menopause, and are an important cause of discomfort, increasing the number of medical appointments. Hormone replacement therapy is an effective treatment, but it can bring undesirable consequences. Alternative treatments exist but they are not universally accepted or effective. The ingestion of malagueta peppers (popular name for fruits of Capsicum frutescens L., Solanaceae) causes sensations similar to those experienced by women during hot flashes. Using the homeopathic law of similars (let like be cured by like), we hypothesized that a homeopathic remedy made of malagueta peppers can be effective in alleviating menopausal hot flashes. We named this remedy Malagueta. METHODS: This randomized, placebo-controlled, double-blind, phase-2 clinical trial was designed to test the hypothesis that, in menopausal women, the homeopathic medicine Malagueta (30 CH), compared with placebo, will significantly reduce the intensity of hot flashes, after 4 weeks of treatment. The primary outcome was the intensity of hot flashes, measured by the Measure Yourself Medical Outcome Profile (MYMOP) instrument. A total of 40 women were enrolled in the study, 20 in each group. RESULTS: The effect of Malagueta on the primary outcome, the intensity of hot flashes, assessed by MYMOP, was superior to that of placebo over the 4 weeks of treatment, with worsening in both groups after treatment was interrupted (after week 4, p < 0.001 in ordinal logistic regression). The odds ratio for treatment response (reduction of at least three MYMOP categories) was 2.78 (95% confidence interval, 0.77 to 10.05). Treatment with Malagueta, compared with placebo, also reduced the intensity of the secondary symptoms (p = 0.001) and improved level of activity (p = 0.025) and well-being (p = 0.008). CONCLUSION: The homeopathic medicine of Capsicum frutescens (Malagueta) was superior to placebo in reducing the intensity of hot flashes in menopausal women after 4 weeks of treatment.

11.
Rev. saúde pública (Online) ; 53: 55, jan. 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1014538

RESUMO

ABSTRACT OBJECTIVE To examine the effect of seasonality on femoral fracture incidence among people residing in the state of São Paulo, Brazil. METHODS Ecological study based on a consecutive series of 216,348 reports of hospital admissions caused by femoral fractures. A Bayesian statistical model was used for time series analysis, considering the monthly average number of events of femoral fractures per day as a dependent variable. RESULTS Among the female population, significant seasonal effects were observed only for older women, aged 60 years or more. Among younger men (aged less than 20 years) there is not a clear seasonal effect, but among the other age groups there seems to exist a higher number of cases of femoral fractures during the coldest months of the year. CONCLUSIONS In general, more cases of fractures occur during the coldest months of the year; however, men and women have different patterns of incidence according to each age group.

12.
CoDAS ; 31(2): e20180174, 2019. tab, graf
Artigo em Português | LILACS-Express | ID: biblio-989661

RESUMO

RESUMO Objetivo Investigar a percepção e a conduta autodeclarada de fonoaudiólogos sobre aspectos éticos e legais relacionados ao uso de imagens de pacientes em redes sociais, comparando tais achados com dados sociodemográficos. Método Para a coleta de dados, utilizou-se um questionário online disponibilizado na plataforma do GoogleDrive, que continha 13 questões abrangendo dados sociodemográficos e questões voltadas para a percepção de fonoaudiólogos quanto ao assunto estudado. A amostra da pesquisa foi composta por 765 participantes. Resultados A maior parte dos respondentes concordou, em algum grau, que o Código de Ética da Fonoaudiologia esclarece sobre o uso de imagens em redes, assim como a publicação de fotos e/ou vídeos de pacientes em redes sociais sem autorização por escrito, constitui infração ética e o direito de imagem está garantido pela Constituição Brasileira. Apenas 18,6% dos fonoaudiólogos afirmaram nunca terem recorrido ao Código de Ética em Fonoaudiologia. Quanto à exibição de fotografias ou vídeos em redes sociais, 5,1% afirmaram ter publicado, em alguma frequência, sem autorização e 21,18% o fizeram apenas com autorização verbal. Praticamente todos os participantes mencionaram já ter visto fotografias ou vídeos de pacientes em redes sociais virtuais postados por fonoaudiólogos. Conclusão Foi possível notar a relevância do estudo para impulsionar debates sobre o assunto e a essencialidade de novos estudos no tema abordado.


ABSTRACT Purpose Investigating the perception and self-reported behavior of speech-language therapist about ethical and legal aspects related to the use of images of patients in social networks, comparing such findings with sociodemographic data. Methods An online questionnaire with 13 questions was the instrument used to collect data related to the demographic data of the participants and to the perception of speech-language therapists. The questionnaire was available on the Google Forms platform e was answered by 765 participants. Results Most participants agreed that the Code of Ethics of Speech-Language Pathology gives information about the use of images in social networks (67.98%), that the publication of photos and / or videos of patients in social networks without authorization by written is an ethical infraction (93.33%) and that the image´s rights is guaranteed by the Brazilian Constitution (89.94%). 18.56% of speech-language pathologists stated that they had never used the Code of Ethics in Speech-Language Pathology. Concerning the exhibition of images in social networks, 5.1% stated that they had shown on their social networks photographs and / or videos without authorization, and 21.18% did so with only verbal authorization. Almost all participants (95.16%) mentioned having seen photographs or videos of patients on virtual social networks posted by speech-language therapist. Conclusion It was possible to verify the relevance of the results obtained and the impact of the research to encourage reflection on the subject.

13.
Artigo em Inglês | LILACS | ID: biblio-1013445

RESUMO

Abstract The aim of this cross-sectional study was to estimate the prevalence of self-reportedhypertension and diabetes among elderly users of primary healthcare facilities in Ribeirão Preto, Brazil, and to investigate the association between these chronic conditions and physical activity and the degree of independence on the performance of activities of daily living. The study included 357 subjects aged 60 years or older. The classification of physical activity was based on the International Physical Activity Questionnaire (IPAQ) and the Pfeffer FunctionalActivities Questionnaire (PFAQ) was applied to assess activities of daily living. Prevalence of diabetes was associated with the level of physical activity, the self-perception of health and the degree of independence on the performance of activities of daily living. No significant associations were found between the prevalence of hypertension and these variables. These findings reinforce the relevance of continuous strategies of management of diabetes in the primary healthcare facilities based on the promotion of physical and occupational activities.


Resumo O objetivo deste estudo transversal foi estimar a prevalência auto-reportada de hipertensãoe diabetes entre idosos usuários das unidades de atenção primária à saúde de Ribeirão Preto, Brasil, e investigar a associação entre estas condições crônicas e a atividade física e o grau de independência na realização das atividades da vida diária. O estudo incluiu 357 participantes com idade de 60 anos ou mais. A classificação da atividade física baseou-se no International Physical Activity Questionnaire (IPAQ), e o Pfeffer Functional Activities Questionnaire (PFAQ) foi aplicado para avaliar a realizaçãodas atividades da vida diária. Prevalência de diabetes foi associada com o nível de atividade física, a autopercepção da saúde e o grau de independência na realização das atividades da vida diária. Não foram encontradas associações significantes entre a prevalência de hipertensão e estas variáveis. Estes achados reforçam a relevância de estratégias contínuas de manejo da diabetes nas unidades de atenção primária à saúde, baseadas na promoção de atividades físicas e ocupacionais.


Assuntos
Humanos , Saúde do Idoso , Diabetes Mellitus , Hipertensão , Atividade Motora , Estilo de Vida
14.
Rev Lat Am Enfermagem ; 26: e3057, 2018 Oct 25.
Artigo em Inglês, Português, Espanhol | MEDLINE | ID: mdl-30379244

RESUMO

OBJECTIVE: to evaluate the effect of preheating on the maintenance of body temperature of patients submitted to elective gynecological surgeries. METHOD: eighty-six patients were randomized, without blinding, to receive usual care (heating with a cotton sheet and blanket) or preheating with a forced air system for 20 minutes (38°C). All patients were actively heated during the intraoperative period. Data were collected from admission of the patient in the surgical center until the end of the surgery. Body temperature was measured during the preoperative and intraoperative periods with an infrared tympanic thermometer. A thermo-hygrometer was used to monitor air temperature and humidity of the operating room. RESULTS: data indicated homogeneity between the groups investigated. There was no statistically significant difference between groups after preheating (p = 0.27). At the end of the surgery, the mean temperature of the groups studied was the same (36.8°C), with a statistically non-significant difference (p = 0.66). CONCLUSION: preheating with the heated forced air system had a similar effect to the usual care in the body temperature of patients submitted to elective gynecological surgeries. ClinicalTrials.gov n. NCT02422758. CAAE, n. 38320814.2.0000.5393.

15.
Vox Sang ; 2018 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-30485453

RESUMO

BACKGROUND AND OBJECTIVES: The objective of the present study was to investigate the fear of blood, injections and fainting as barriers to blood donation in a sample of primary healthcare users in a Brazilian municipality. MATERIALS AND METHODS: This is a cross-sectional survey of primary care patients in 12 randomly selected healthcare facilities in Ribeirão Preto, Brazil in 2015-2016. Key variables were lifetime blood donation history, intentions to donate blood among non-donors and current donation practice. To assess fear of blood in general (FBG), fear of injections in general (FIG) and fear of fainting due to fear of injection (FFI), we used the Blood Injection/Fear Scale (BIFS). We tested associations between variables using regression models and conditional inference trees (CIT). RESULTS: A total of 1055 primary healthcare users participated (79·7% female, mean age 40·6 years [SD = 15·2]), 63·4% never donated blood, 13·3% reported they are unable to donate, 6·1% donated only once, 17·2% donated multiple times. Women had higher scores for FIG and FBG. FFI was associated with middle socioeconomic status. Those who never intended to donate exhibited the highest scores in the three dimension of fear. By CIT analysis, being female and high scores for FBG are associated with decreased blood donation. Among males, blood donation frequency is low among those aged 33 years and under. CONCLUSION: Fear of blood, injections and fainting are barriers to blood donation in Brazil. Efforts to recruit and retain blood donors should convey information on blood donation processes and address misconceptions that may increase fear.

16.
Hematol Transfus Cell Ther ; 40(4): 368-376, 2018 Oct-Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30370416

RESUMO

Background: To present the results of the application of the Blood Donation Knowledge Questionnaire in a large and representative sample of users of primary care services in order to extend the evaluation of the metrics of the items and to assess knowledge about blood donation in association with sociodemographic variables. Method: The Blood Donation Knowledge Questionnaire is composed of 24 items based on blood donation requirements of the Brazilian Ministry of Health and on some popular beliefs and concepts of the Brazilian population regarding the blood donation process. Data collection was carried out in 12 healthcare facilities of Ribeirão Preto, São Paulo. The analysis of items was performed using classical test theory with associations being assessed using the multivariate Tobit regression model. Results: A total of 1055 individuals participated (79.7% females and a mean age of 40.6 years). Previous blood donation was reported by 246 (23.3%) participants, 669 (63.4%) had never donated, and 140 (13.3%) reported being ineligible to donate blood. This questionnaire is comprised of items considered easy-to-understand, with a facility level of medium to high and generally an adequate capability of discrimination. Higher means of correct answers were detected among females, individuals with more schooling, and subjects who had already donated blood. Conclusion: The Blood Donation Knowledge Questionnaire is an instrument that aims to measure some general aspects of knowledge regarding blood donation and can be used in different contexts. There is evidence that knowledge of primary healthcare users regarding blood donation is correlated to sex, educational level, and previous blood donation.

17.
Artigo em Inglês | MEDLINE | ID: mdl-30352028

RESUMO

Purpose To investigate, through a spatio-temporal analysis, the association between the percentages of live births of adolescent mothers (LBAM) and the human development index (HDI), including the three components: income, education and longevity. Methods The percentage of LBAM was obtained from the Brazilian Live Births Information System for the state of Minas Gerais, Brazil in the period 2000-2015 and the HDI data and its components were obtained from United Nations Development Program's (UNDP) Human Development Reports. A generalized additive model (GAM) was used to estimate the relative risk of LBAM in relation to the HDI and to identify spatial clusters of the geographical distribution of LBAM, the Moran global and local index was used. Results There is an association between the HDI and its components with LBAM. The high values of relative risk are spatially concentrated in the northern part of the state of Minas Gerais. The graphs indicated a nonlinear relationship between LBAM over the years. Conclusions There is a strong spatial dependence of LBAM in Minas Gerais, which suggests that a geographical location plays a fundamental role in understanding it. The regional disparity confirmed in this study is inherent in the process of human development, it is important for planning actions aimed at the development of these regions in order to minimize existing disparities.

18.
Hematol., Transfus. Cell Ther. (Impr.) ; 40(4): 368-376, Oct.-Dec. 2018. tab
Artigo em Inglês | LILACS-Express | ID: biblio-984499

RESUMO

ABSTRACT Background: To present the results of the application of the Blood Donation Knowledge Questionnaire in a large and representative sample of users of primary care services in order to extend the evaluation of the metrics of the items and to assess knowledge about blood donation in association with sociodemographic variables. Method: The Blood Donation Knowledge Questionnaire is composed of 24 items based on blood donation requirements of the Brazilian Ministry of Health and on some popular beliefs and concepts of the Brazilian population regarding the blood donation process. Data collection was carried out in 12 healthcare facilities of Ribeirão Preto, São Paulo. The analysis of items was performed using classical test theory with associations being assessed using the multivariate Tobit regression model. Results: A total of 1055 individuals participated (79.7% females and a mean age of 40.6 years). Previous blood donation was reported by 246 (23.3%) participants, 669 (63.4%) had never donated, and 140 (13.3%) reported being ineligible to donate blood. This questionnaire is comprised of items considered easy-to-understand, with a facility level of medium to high and generally an adequate capability of discrimination. Higher means of correct answers were detected among females, individuals with more schooling, and subjects who had already donated blood. Conclusion: The Blood Donation Knowledge Questionnaire is an instrument that aims to measure some general aspects of knowledge regarding blood donation and can be used in different contexts. There is evidence that knowledge of primary healthcare users regarding blood donation is correlated to sex, educational level, and previous blood donation.

19.
Medicina (Ribeiräo Preto) ; 51(3): 177-188, jul.-set. 2018.
Artigo em Português | LILACS | ID: biblio-979599

RESUMO

Modelo do estudo: Estudo transversal. Introdução: O tratamento farmacológico é a primeira opção para o tratamento da epilepsia, e cerca de 40% dos pacientes necessitam de politerapia para melhor controle das crises epilépticas, o que pode estar associado ao aumento de eventos adversos e comprometimento da qualidade de vida. Objetivos: Avaliar a qualidade de vida de pacientes com epilepsia farmacoresistente em uso de lamotrigina (LTG), bem como verificar a associação dos eventos adversos dos antiepilépticos com a qualidade de vida. Metodologia: Este estudo transversal foi realizado com 75 pacientes com epilepsia farmacorresistente em uso LTG atendidos em um Ambulatório de Epilepsia de Difícil Controle de Ribeirão Preto-SP, no período de maio/2011 a abril/2012. As variáveis clínicas analisadas foram a qualidade de vida (Quality of Life in Epilepsy - Qolie-31) e o perfil de eventos adversos (AEP ­ Adverse Events Profile Questionnaire). Dados sociodemográficos e farmacoterapêuticos foram coletados através dos prontuários dos pacientes. Este trabalho foi aprovado pelo Comitê de Ética em Pesquisa do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HCFMRP-USP), cujo número do processo é 8791/2010. Resultados: Os eventos adversos mais frequentes foram sonolência e dificuldade de concentração. Além disso, observou-se baixos escores em todos os domínios relacionados à qualidade de vida (Qolie-31). Conclusão: A qualidade de vida possui associação inversamente significativa com os eventos adversos, nos pacientes em uso de antiepilépticos (p<0,01). (AU)


Study design: Cross-sectional study. Introduction: Pharmacological treatment is the first option to treat epilepsy, and about 40% of patients require polytherapy to better control epileptic seizures, which may be associated with an increase in adverse events and impairment of quality of life. Objective: To evaluate the quality of life of patients with pharmacoresistant epilepsy using lamotrigine (LTG), as well as to verify the association of adverse events with antiepileptic drugs with quality of life. Methods: This cross-sectional study was carried out with 75 patients with drugresistant epilepsy using LTG, in a Clinic of Epilepsy of Difficult Control of Ribeirão Preto-SP, from May/2011 to April / 2012. The clinical variables analyzed were Quality of Life in Epilepsy (QOLIE31) and the Adverse Events Profile Questionnaire (AEP). Socio-demographic and pharmacotherapeutic data were collected through patient records. This study was approved by the Research Ethics Committee of the General Hospital of the Medical School of Ribeirão Preto of the University of São Paulo (HCFMRP-USP), whose case number is 8791/2010. Results: The most frequent adverse events were somnolence and difficulty concentrating. In addition, low scores were observed in all domains related to quality of life (Qolie-31). Conclusion: Quality of life has an inverse association with adverse events in patients using antiepileptic drugs (p <0.01). (AU)


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Qualidade de Vida , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos , Epilepsia Resistente a Medicamentos
20.
Virol J ; 15(1): 112, 2018 07 24.
Artigo em Inglês | MEDLINE | ID: mdl-30041676

RESUMO

BACKGROUND: Chikungunya (CHIKV) virus is an important mosquito-borne virus causing outbreaks of acute febrile illness with arthropathy. The detection of specific antibodies against CHIKV is used for diagnosis after the acute viremic phase of the disease. However, a major challenge for serologic diagnosis of CHIKV and other alphaviruses is the cross-reactivity of antibodies to common antigens among these viruses. In the present study, we have developed an enzyme-linked immunosorbend assay using a recombinant envelope protein 2 of CHIKV produced in Escherichia coli system, as a capture antigen. RESULTS: High titers (1600 to 12,800) of anti-CHIKV antibodies were detected in human sera analyzed by the CHIKV assay, suggesting it may detect low levels of the antibodies presence. On the other side, cross-reactivity was not observed in mouse hyperimmune sera to Mayaro virus and other alphaviruses analyzed by the CHIKV immunosorbend assay, suggesting it is a CHIKV-specific test. Fifty-nine human serum samples of CHIKV infection suspected cases were tested for immunoglobulin G (IgG) and M (IgM) antibodies detection using the CHIKV immunosorbend assay. A total of 44% (26/59) of samples were positive for IgG to CHIKV, determining 89.66% sensitivity and 100% specificity when the assay is compared to a CHIKV-specific neutralization assay. In addition, 40.6% (24/59) of samples were positive for IgM, determining 92.48% sensitivity and 79.04% specificity by a Bayesian method in the absence of a gold standard. Moreover, CHIKV immunosorbend assay showed similar sensibilities to a commercial immunochromatography assay (Lumiquick, USA) for CHIKV IgG and IgM detection. CONCLUSION: In short, we have developed a rapid, simple, specific and sensitive CHIKV immunosorbend assay for IgG and IgM detection and our results showed potential applicability on the diagnosis of infections by this virus.


Assuntos
Antígenos Virais/imunologia , Febre de Chikungunya/diagnóstico , Febre de Chikungunya/imunologia , Vírus Chikungunya/imunologia , Ensaio de Imunoadsorção Enzimática , Proteínas do Envelope Viral/imunologia , Anticorpos Neutralizantes/imunologia , Anticorpos Antivirais/imunologia , Humanos , Imunoglobulina G/sangue , Imunoglobulina G/imunologia , Imunoglobulina M/sangue , Imunoglobulina M/imunologia , Testes de Neutralização , Proteínas Recombinantes , Sensibilidade e Especificidade
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