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1.
Soins ; 64(841): 40-45, 2019 Dec.
Artigo em Francês | MEDLINE | ID: mdl-31864512

RESUMO

Located across three sites in Ile-de-France, the Institut Curie combines care, research and teaching activities to fight cancer. Faced with the progression of ambulatory care, the departments have had to adapt in order to improve patient support and oversee community-hospital coordination. Nurses become involved just after the disclosure of the diagnosis by the doctor, but also coordinate the patient's pathway in ambulatory care. They anticipate the needs of the teams, the patients and their carers. Patients appreciate their availability and the fact that they have a single contact person.


Assuntos
Hospital Dia , Neoplasias/tratamento farmacológico , França , Humanos
2.
Rev Infirm ; 67(240): 29, 2018 Apr.
Artigo em Francês | MEDLINE | ID: mdl-29609788

RESUMO

A health application is aimed at patients undergoing treatment at home, with chemotherapy or targeted therapy, administered orally. Medical safety, the collaborative approach, data protection and the respect of patients' rights form part of the ethical charter of this innovative project.


Assuntos
Serviços Hospitalares de Assistência Domiciliar , Aplicativos Móveis , Neoplasias/tratamento farmacológico , Telemedicina , Humanos
3.
J Ind Microbiol Biotechnol ; 34(6): 423-31, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17333091

RESUMO

Two Rhodococcus erythropolis isolates, named A66 and A69, together with the well-characterized R. erythropolis strain IGTS8 were compared biochemically and genetically. Both isolates, like strain IGTS8, desulfurized DBT to 2-hydroxybiphenyl (2-HBP), following the 4S pathway of desulfurization. Strain IGTS8 showed the highest (81.5%) desulfurization activity in a medium containing DBT at 30 degrees C. Strain A66 showed approximately the same desulfurization activity either when incubated at 30 degrees C or at 37 degrees C, while strain A69 showed an increase of desulfurization efficiency (up to 79%) when incubated at 37 degrees C. Strains A66 and A69 were also able to grow using various organosulfur or organonitrogen-compounds as the sole sulfur or nitrogen sources. The biological responses of A66, A69 and IGTS8 strains to a series of mutagens and environmental agents were evaluated, trying to mimic actual circumstances involved in exposure/handling of microorganisms during petroleum biorefining. The results showed that strains A69 and IGTS8 were much more resistant to UVC treatment than A66. The three desulfurization genes (dszA, dszB and dszC) present in strains A66 and A69 were partially characterized. They seem to be located on a plasmid, not only in the strain IGTS8, but also in A66 and A69. PCR amplification was observed using specific primers for dsz genes in all the strains tested; however, no amplification product was observed using primers for carbazole (car) or quinoline (qor) metabolisms. All this information contributes to broaden our knowledge concerning both the desulfurization of DBT and the degradation of organonitrogen compounds within the R. erythropolis species.


Assuntos
Rhodococcus/classificação , Microbiologia do Solo , Poluentes do Solo/metabolismo , Enxofre/metabolismo , Tiofenos/metabolismo , Técnicas de Tipagem Bacteriana , Meios de Cultura , DNA Bacteriano/análise , DNA Bacteriano/isolamento & purificação , Genes de RNAr , Genótipo , Dados de Sequência Molecular , Nitrogênio/metabolismo , Petróleo , Fenótipo , RNA Ribossômico 16S/genética , Rhodococcus/genética , Rhodococcus/isolamento & purificação , Rhodococcus/metabolismo , Análise de Sequência de DNA
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