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1.
Rev Med Inst Mex Seguro Soc ; 57(1): 30-35, 2019 Apr 01.
Artigo em Espanhol | MEDLINE | ID: mdl-31071252

RESUMO

The residual risk of transfusion-related infections has decreased dramatically in countries that have routinely implemented serological screening. Most of the donation in Mexico is from replacement practice, a risk factor for positive serology. In Mexico, the altruistic donation is only 2.7%. The heterogeneity of technical factors, regional factors and internal policies of each center influences the variability of data on the prevalence of positive screening, as well as the prevalence of confirmed cases. The main advantage of nucleic acid technology is the detection of donors in the period of serological window or occult infections, being occult hepatitis reports in Mexican donors from 1 to 3.4%. The limitation of available technology, the scope of the clinic and perspectives, invites us to improve technology and health policies in the interest of transfusion safety.

2.
Rev. peru. med. exp. salud publica ; 35(4): 684-688, oct.-dic. 2018. graf
Artigo em Espanhol | LILACS-Express | ID: biblio-985791

RESUMO

RESUMEN La hidatidosis es una infección zoonótica que puede invadir múltiples órganos en el ser humano. Sin embargo, el tejido subcutáneo es el órgano menos afectado por esta enfermedad, cuando esto ocurre se aprecia escasa sintomatología, lo que ocasiona periodos prolongados de enfermedad asociado a diagnóstico tardío y a una pobre respuesta a la terapia antiparasitaria. La sierra central del Perú es la zona con mayor prevalencia, presumiblemente por las inadecuadas medidas de saneamiento ambiental, la falta de educación y las casi inexistentes medidas de control de la enfermedad. Con el objetivo de discutir los problemas relacionados a la localización subcutánea y su probable fisiopatología, reportamos dos casos de hidatidosis subcutánea que se presentaron con lesiones tumorales de evolución prolongada y que no afectaron al hígado ni a los pulmones y que finalmente fueron tratados mediante extirpación quirúrgica debido a la falta de respuesta al tratamiento con albendazol.


ABSTRACT Hydatidosis is a zoonotic infection that can invade many organs in the human being. Nevertheless, the subcutaneous tissue is the less affected organ by this disease. When this disease appears, little symptomatology is observed, which causes prolonged periods of disease associated to delayed diagnosis and a poor answer to the antiparasitic therapy. The central mountain range of Peru is the geographical zone with the greatest prevalence, presumably due to the inadequate measures of environmental sanitation, the lack of education and the almost non-existent control measures of the disease. With the aim to discuss the problems related to the subcutaneous location and its probable physiopathology, this study reports two cases of subcutaneous hydatidosis that appeared with tumor lesions with a prolonged evolution and that did not affect the liver or the lungs and which were finally treated by means of surgical removal due to the lack of response to treatment with albendazol.

3.
Am J Infect Control ; 2018 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-30442444

RESUMO

According to the US Advisory Committee on Immunization Practices recommendations, only health care personnel (HCP) with adequate evidence of immunity should be exposed to patients with a suspected diagnosis of mumps. Here we report a hospital-outbreak scenario among medical residents with no previous vaccination record against mumps who had a high rate of complications. We also describe the importance and impact of full and proper vaccination, as well as isolation, of HCP in stopping the outbreak and, finally, review opportunities for improving the safety of HCP.

4.
Afr J Infect Dis ; 12(2): 47-54, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30109286

RESUMO

Background: The changes in body composition markers (weight, fat mass, lean mass, and BMI) over time can be associated with TB treatment outcome among HIV-infected patients. The aim of this study was to investigate whether changes in fat mass and lean mass were associated with the treatment response among patients with HIV infection and pulmonary tuberculosis. Materials and Methods: This was a prospective cohort study. Data from HIV-infected patients commencing TB therapy were analyzed. This included body weight measurement using bioimpedance equipment at baseline, one month, and two months after starting TB treatment. Results: The study was conducted in 125 patients, 17 patients (13.6%) died during treatment, of which 5 died during the first month of treatment, 4 during the second month and 8 after the second month. The group of patients with good response, increased their weight by 1.3 kg (p <0.001) at the end of the first month of TB treatment and 2.6 kg in the second month (p <0.001), and body fat increase was 1.2 Kg (p <0.001) and 2.3 kg (p <0.001), the first and second month respectively. The group of patients who died had lost 2.1 kg fat mass after the first month (p <0.001) and 3.7 kg in the second month (p <0.001). Conclusions: Our results show that the weight change during TB treatment (increased fat mass) helps us predict therapeutic response. Weight loss during the first month of starting therapy should be evaluated thoroughly to identify the probable cause of treatment failure.

5.
Rev Peru Med Exp Salud Publica ; 35(4): 684-688, 2018.
Artigo em Espanhol | MEDLINE | ID: mdl-30726435

RESUMO

Hydatidosis is a zoonotic infection that can invade many organs in the human being. Nevertheless, the subcutaneous tissue is the less affected organ by this disease. When this disease appears, little symptomatology is observed, which causes prolonged periods of disease associated to delayed diagnosis and a poor answer to the antiparasitic therapy. The central mountain range of Peru is the geographical zone with the greatest prevalence, presumably due to the inadequate measures of environmental sanitation, the lack of education and the almost non-existent control measures of the disease. With the aim to discuss the problems related to the subcutaneous location and its probable physiopathology, this study reports two cases of subcutaneous hydatidosis that appeared with tumor lesions with a prolonged evolution and that did not affect the liver or the lungs and which were finally treated by means of surgical removal due to the lack of response to treatment with albendazol.


Assuntos
Equinococose , Tela Subcutânea/parasitologia , Idoso , Equinococose/diagnóstico , Equinococose/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Peru
6.
Rev Peru Med Exp Salud Publica ; 34(3): 445-450, 2017 Jul-Sep.
Artigo em Espanhol | MEDLINE | ID: mdl-29267768

RESUMO

The objective of the present study was to calculate the economic loss caused by the treatment of human hydatidosis. For this purpose, a cost analysis of the cases reported in the Junin region of Peru in 2013 was conducted. The total cost (direct and indirect) per patient assisted by the Ministry of Health (Ministerio de Salud-Minsa), the social security system (EsSalud), and private health care was 1,220, 3,051, and 4,090 US dollars (USD), respectively. The mean annual loss considering the number of health care services for uncomplicated cases of human hydatidosis was USD 24,542 in Minsa, USD 369,292 in EsSalud, and USD 130,566 in private health care. Overall, the rate of loss of human productivity was a small proportion. Our findings indicate that hydatidosis imposes a heavy economic burden in the Junin region of Peru.


Assuntos
Equinococose/economia , Gastos em Saúde , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Custos e Análise de Custo , Equinococose/diagnóstico , Equinococose/terapia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Peru , Adulto Jovem
7.
Rev. peru. med. exp. salud publica ; 34(3): 445-450, jul.-sep. 2017. tab
Artigo em Espanhol | LILACS-Express | ID: biblio-902928

RESUMO

RESUMEN El objetivo del presente estudio fue determinar la pérdida económica que ocasiona el tratamiento de la hidatidosis humana, para lo cual se realizó un análisis de costos de los casos reportados en la región Junín en Perú, durante el año 2013. El costo total (directo e indirecto) en dólares americanos por paciente atendido por el Ministerio de Salud (Minsa) fue USD 1 220,0; por el seguro social (EsSalud) fue USD 3 051,0 y por la atención privada fue USD 4 090,7. La pérdida media anual según el número de atenciones por hidatidosis humana no complicada fue USD 24 542,0 en el Minsa, USD 369 292,0 en EsSalud y USD 130 566,4 en la atención privada. Las pérdidas de productividad humana constituyen la minoría. Nuestros hallazgos indican que la hidatidosis impone una pesada carga económica en la región Junín.


ABSTRACT The objective of the present study was to calculate the economic loss caused by the treatment of human hydatidosis. For this purpose, a cost analysis of the cases reported in the Junin region of Peru in 2013 was conducted. The total cost (direct and indirect) per patient assisted by the Ministry of Health (Ministerio de Salud-Minsa), the social security system (EsSalud), and private health care was 1,220, 3,051, and 4,090 US dollars (USD), respectively. The mean annual loss considering the number of health care services for uncomplicated cases of human hydatidosis was USD 24,542 in Minsa, USD 369,292 in EsSalud, and USD 130,566 in private health care. Overall, the rate of loss of human productivity was a small proportion. Our findings indicate that hydatidosis imposes a heavy economic burden in the Junin region of Peru.

8.
Infectio ; 20(1): 38-41, ene.-mar. 2016. ilus, tab
Artigo em Espanhol | LILACS-Express | ID: lil-770876

RESUMO

La otitis externa maligna es considerada una infección invasiva del conducto auditivo externo, infrecuente y sumamente agresiva, que llega, en ocasiones, a comprometer la base del cráneo. Se presenta habitualmente en inmunocomprometidos, incluidos aquellos con infección por VIH. El ectima gangrenoso es una infección cutánea localizada, inusual, causada, en la mayoría de los casos por Pseudomonas aeruginosa, con compromiso multisistémico y evolución tórpida. La asociación entre ambas entidades es aún más rara. A continuación, presentamos el caso de una mujer de 37 años, con el antecedente principal de infección por VIH desde hace 10 años, adherente al tratamiento antirretroviral y, a pesar de mantener una adecuada respuesta inmunológica y virológica, se presenta a la urgencia de nuestro hospital en shock séptico por otitis externa maligna, con ectima gangrenoso y posible síndrome hemofagocítico como complicación, aislándose Pseudomonas aeruginosa como agente causal.


Malignant otitis externa is an aggressive, infrequent and invasive infection of the external auditory canal. In some cases it leads to skull base compromise, particularly in immunocompromised individuals, including HIV-positive patients. Ecthyma gangrenosum is an unusual, localized cutaneous infection, caused mostly by Pseudomonas aeruginosa, with systemic compromise and a torpid evolution. An association between these 2 entities is even more rare. We present the case of a 37-year old woman with a history of 10 years’ HIV infection and good adherence to antiretroviral therapy. Although she had an adequate immunological and virological response, she presented at our emergency department in septic shock due to malignant otitis externa with ecthyma gangrenosum and possible haemophagocytic syndrome as a complication, with Pseudomonas aeruginosa determined to be the causative agent.

9.
Am J Infect Control ; 44(2): 250-2, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26585250

RESUMO

A comparison of 2 different influenza seasons (2013-2014 and 2014-2015) where early vaccination among health care providers (HCPs) in the latter was the difference. Differences in leave of absence because of influenza-like illness (ILI) (52 vs 15 [total number of leave of absence issued], P < .001) and total days of lost work (218 vs 68, P < .001) were found for the 2013-2014 and 2014-2015 seasons, respectively. An association between earlier influenza vaccination among HCPs and a reduction in ILI, leave of absence, and days of lost work was found.


Assuntos
Pessoal de Saúde/estatística & dados numéricos , Vacinas contra Influenza/administração & dosagem , Influenza Humana/prevenção & controle , Vacinação , Hospitais de Ensino , Humanos , Influenza Humana/epidemiologia , México/epidemiologia , Estudos Retrospectivos , Síndrome , Fatores de Tempo
10.
Rev Med Inst Mex Seguro Soc ; 51(5): 522-31, 2013 Sep-Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-24144146

RESUMO

BACKGROUND: women with endometriosis may have a decreased bone mineral density (BMD). Several studies have shown that accumulation of adipose tissue profoundly affects BMD. It has also been documented that excess body fat is associated with risk of developing endometriosis. The aim was to analyze the relationship between BMD, fat mass, and the insulin-glucose axis in women with endometriosis. METHODS: thirty women with a diagnosis of endometriosis established by surgery were enrolled to participate in an observational prospective study. Anthropometry was performed to determine body mass index, and a dual X-ray densitometry to collect data on body composition and BMD. Glucose and insulin determinations were performed. Women were divided in two groups: with normal weight (n = 18) or overweight (n = 12). For the analysis of the results, we used descriptive statistics and Pearson's test. RESULTS: normal weight/overweight: mean age 32.5/35.2 years; body mass index 21.5/30.2; adiposity index: 27.7 %/36.1 %; fat mass index: 35.4/45.8 %; overweight women showed a significant value with p < 0.05. CONCLUSIONS: overweight, high values of adiposity index and fat mass index were related to endometriosis. This could support the hypothesis about a common pathogenesis among endometriosis, osteoporosis, diabetes and obesity.


Assuntos
Composição Corporal , Pesos e Medidas Corporais , Densidade Óssea , Endometriose/metabolismo , Glucose/metabolismo , Adulto , Estudos Transversais , Feminino , Humanos , Projetos Piloto , Estudos Prospectivos
11.
Rev Peru Med Exp Salud Publica ; 30(2): 326-30, 2013 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-23949523

RESUMO

The Cystoisospora belli, before denominated as Isospora belli, is the etiologic agent of cystoisosoporiasis, an opportunistic infection affecting immunocompromised patients, characterized by chronic diarrhea and weight loss. The incidence of chronic diarrhea for this agent, in HIV patients, has decreased considerably. This thanks to the advent of highly active antiretroviral therapy (HAART), which has improved the patient's immune response and decrease viral load. We present six cases of cystoisosoporiasis recurrent and refractory to treatment in HIV patients, who was being treated with with trimethoprim / sulfamethoxazole (TMP / SMX) orally as a prophylaxis. Five of these patients passed away due to the infection, despite of the fact that they had a good response to HAART (adequate increase in CD4 and viral load undetectable) and they had been treated with second line drugs.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS , Terapia Antirretroviral de Alta Atividade , Coccidiose , Infecções por HIV/tratamento farmacológico , Sarcocystidae , Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Infecções Oportunistas Relacionadas com a AIDS/terapia , Síndrome de Imunodeficiência Adquirida/tratamento farmacológico , Adulto , Coccidiose/diagnóstico , Coccidiose/tratamento farmacológico , Diarreia/parasitologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva
12.
Rev. peru. epidemiol. (Online) ; 17(2): 1-6, mayo.-ago. 2013. ilus, tab, graf
Artigo em Espanhol | LILACS | ID: lil-706064

RESUMO

Objetivo: Determinar los factores asociados a mortalidad en pacientes con neumon¡a nosocomial en el Hospital Dos de Mayo, Lima-Perú entre el per¡odo enero 2006-diciembre 2010. Métodos: Se realizó un estudio de cohorte única, retrospectivo, de pacientes con diagnóstico de neumon¡a nosocomial. Los pacientes elegibles para el estudio fueron mayores de 18 años, tiempo de enfermedad y condicón de egreso conocido (alta o fallecido). Para el análisis de supervivencia se utilizó el método de Kaplan-Meier y regresión de Cox. Resultados: Se identificaron 658 pacientes con diagnóstico de neumon¡a nosocomial, el agente causal fue identificado en 173 (26,75%) casos. La edad media fue 58,4ñ19,6 años, fallecieron 238 (36,2%) pacientes, la mediana de supervivencia fue de 16 d¡as. El sexo masculino presentó un hazard ratio (HR) de 1,15 (IC 95%: 0,89 a 1,49). A los 10 y 20 d¡as la tasa de supervivencia fue de 70% y 40% en aquellos pacientes con Klebsiella, 85% y 75% en aquellos con Pseudomonas, y el 70% y 65% en aquellos con Staphylococcus aureus. En el análisis multivariado, se identificaron a la exposición a ventilación mecánica (HR 1,98; IC95% 1,35-2,89), el uso de una sonda nasogástrica (HR 1,33; IC95% 1,01-1,76) y la edad mayor de 65 años (HR 1,96; IC95% 1,51-2,55) como factores asociados a mortalidad, mientras que la resistencia a ceftazidima y amikacina presentó HR 1,45 (IC95% 0,74-2,84). Conclusiones: En la neumon¡a nosocomial, la exposición a ventilación mecánica, sonda nasogástrica y edad mayor de 65 años, se asoció con una menor supervivencia. Esto sugiere la instauración de medidas preventivas en este grupo de riesgo.


Objective: To determine factors associated with mortality in patients with nosocomial pneumonia at the Hospital Dos de Mayo, Lima-Peru between January 2006 to December 2010. Methods: Retrospective cohort study, patients eligible for the study were over 18 years of age, sick time record and known exit condition (discharge or deceased). For survival analysis we used the Kaplan-Meier and Cox regression. Results: We identified 658 patients diagnosed with nosocomial pneumonia, and the causative agent was identified in 173 (26,75%). The mean age was 58,4ñ19,6 years, 238 patientes died (36,2%); median survival time was 16 days. Male sex presented HR=1,15, 95%CI 0.89-1.49. At 10 and 20 days the survival rate was 70% and 40% in those with Klebsiella, 85% and 75% in those with Pseudomonas, and 70% and 65% in those with Staphylococcus aureus. In the multivariate analysis, we identified exposure to mechanical ventilation (HR 1,98; 95%CI 1,35 to 2,89), use of a nasogastric tube (HR 1,33; 95%CI 1,01 to 1,76) and age over 65 years (HR 1,96; (95%CI 1,51 to 2,55) as factors associated with mortality, while resistance to ceftazidime and amikacin present HR 1,45 (95%CI 0,74 -2,84). Conclusions: In nosocomial pneumonia, the exposure to mechanical ventilation, nasogastric tube and age over 65 years, are associated with lower survival. This suggests the introduction of preventive measures in this risk group.


Assuntos
Feminino , Pessoa de Meia-Idade , Adulto Jovem , Infecção Hospitalar , Pneumonia/mortalidade , Estudos de Coortes , Estudos Retrospectivos
13.
Rev. peru. med. exp. salud publica ; 30(2): 326-330, abr.-jun. 2013. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-681000

RESUMO

La Cystoisospora belli, antes denominada Isospora belli, es el agente etiológico de la cystoisosporiasis, una infección oportunista que afecta a pacientes inmunodeprimidos, caracterizada por diarrea crónica y pérdida ponderal. La incidencia de diarrea crónica por este agente, en pacientes infectados por el VIH, ha disminuido considerablemente. Ello gracias al advenimiento de la terapia antirretroviral de gran actividad (TARGA), con la que se ha logrado mejorar la respuesta inmunológica del paciente y disminuir su carga viral. Se presentan seis casos de cystoisosporiasis recurrente y refractaria en pacientes con infección por VIH, en quienes se diagnosticó cystoisosporiasis pese a que previamente se encontraban recibiendo profilaxis con trimetropin/sulfametoxazol (TMP/SMX). Cinco de ellos evolucionaron de manera tórpida y fallecieron, a pesar de una buena respuesta al TARGA (adecuado incremento de CD4 y disminución de la carga viral hasta rangos indetectables), y de tratamiento con TMP/SMX por vía oral y otros medicamentos de segunda línea.


The Cystoisospora belli, before denominated as Isospora belli, is the etiologic agent of cystoisosoporiasis, an opportunistic infection affecting immunocompromised patients, characterized by chronic diarrhea and weight loss. The incidence of chronic diarrhea for this agent, in HIV patients, has decreased considerably. This thanks to the advent of highly active antiretroviral therapy (HAART), which has improved the patient’s immune response and decrease viral load. We present six cases of cystoisosoporiasis recurrent and refractory to treatment in HIV patients, who was being treated with with trimethoprim / sulfamethoxazole (TMP / SMX) orally as a prophylaxis. Five of these patients passed away due to the infection, despite of the fact that they had a good response to HAART (adequate increase in CD4 and viral load undetectable) and they had been treated with second line drugs.


Assuntos
Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Infecções Oportunistas Relacionadas com a AIDS , Terapia Antirretroviral de Alta Atividade , Coccidiose , Infecções por HIV/tratamento farmacológico , Sarcocystidae , Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Infecções Oportunistas Relacionadas com a AIDS/terapia , Síndrome de Imunodeficiência Adquirida/tratamento farmacológico , Coccidiose/diagnóstico , Coccidiose/tratamento farmacológico , Diarreia/parasitologia , Recidiva
14.
Rev Peru Med Exp Salud Publica ; 27(3): 466-9, 2010 Sep.
Artigo em Espanhol | MEDLINE | ID: mdl-21152742

RESUMO

We report the case of a male newborn, product of a 36 week pregnancy, with diagnosis of congenital pneumonia and with a confirmatory test for influenza A (H1N1) virus, without any other suspicious contact. The mother was admitted to the hospital with respiratory failure and the history of a flu-like episode of 5 days of evolution, during the first days of the pandemic in Peru. Due to the severe evolution of the respiratory process, assisted ventilation was given to her and then a cesarean section was performed due to acute fetal distress and oligoamnios. The mother was later confirmed as a case of epidemic influenza A (H1N1) and pulmonary tuberculosis.


Assuntos
Transmissão Vertical de Doença Infecciosa , Vírus da Influenza A Subtipo H1N1 , Influenza Humana/diagnóstico , Influenza Humana/transmissão , Humanos , Recém-Nascido , Masculino
15.
Rev Peru Med Exp Salud Publica ; 27(2): 292-5, 2010 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-21072484

RESUMO

We describe a case of a 47 years old male, with a history of 2 days of progressive, ascendant, symmetrical weakness in the lower extremities; a lumbar puncture was performed after the brain CT scan, as well as an electromyography, evidencing pure motor polyradiculopathy with axonal pattern, compatible with Guillain Barre syndrome. Afterwards, he received four plasmapheresis sessions, with clinical improvement from the second session. Due to his epidemiological background, Brucella set testing was done. Rose Bengal was positive, antibiotic treatment with rifampin and doxicicline was initiated, as well as rehabilitation. Three months later the patient recovered completely. The relevance of early treatment with plasmapheresis and the definition of the etiologic diagnosis determine that the prognosis of the Guillain Barre syndrome is favorable.


Assuntos
Brucelose/complicações , Síndrome de Guillain-Barré/microbiologia , Adulto , Humanos , Masculino
16.
Rev. peru. med. exp. salud publica ; 27(3): 466-469, jul.-set. 2010. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-571083

RESUMO

Se reporta el caso de un recién nacido varón, producto de embarazo de 36 semanas, con diagnóstico de neumonía congénita y examen confirmatorio de infección por el virus de la influenza A (H1N1), sin ningún otro tipo de contacto sospechoso. La madre ingresó al hospital con insuficiencia respiratoria y antecedente de proceso gripal de cinco días de evolución, durante los primeros días de la pandemia en el Perú. Por la evolución grave del proceso respiratorio, se le administró ventilación mecánica para luego ser sometida a cesárea por sufrimiento fetal agudo y oligoamnios. Se confirmó en la madre infección por el virus de la influenza A H1N1 epidémico y tuberculosis pulmonar.


We report the case of a male newborn, product of a 36 week pregnancy, with diagnosis of congenital pneumonia and with a confirmatory test for influenza A (H1N1) virus, without any other suspicious contact. The mother was admitted to the hospital with respiratory failure and the history of a flu-like episode of 5 days of evolution, during the first days of the pandemic in Peru. Due to the severe evolution of the respiratory process, assisted ventilation was given to her and then a cesarean section was performed due to acute fetal distress and oligoamnios. The mother was later confirmed as a case of epidemic influenza A (H1N1) and pulmonary tuberculosis.


Assuntos
Humanos , Sofrimento Fetal , Transmissão Vertical de Doença Infecciosa , Vírus da Influenza A Subtipo H1N1 , Trabalho de Parto Prematuro , Pneumonia Viral , Peru
17.
Rev. peru. med. exp. salud publica ; 27(3): 466-469, jul.-set. 2010. ilus, tab
Artigo em Espanhol | PERNAL | ID: pnc-7896

RESUMO

Se reporta el caso de un recién nacido varón, producto de embarazo de 36 semanas, con diagnóstico de neumonía congénita y examen confirmatorio de infección por el virus de la influenza A (H1N1), sin ningún otro tipo de contacto sospechoso. La madre ingresó al hospital con insuficiencia respiratoria y antecedente de proceso gripal de cinco días de evolución, durante los primeros días de la pandemia en el Perú. Por la evolución grave del proceso respiratorio, se le administró ventilación mecánica para luego ser sometida a cesárea por sufrimiento fetal agudo y oligoamnios. Se confirmó en la madre infección por el virus de la influenza A H1N1 epidémico y tuberculosis pulmonar. (AU)


We report the case of a male newborn, product of a 36 week pregnancy, with diagnosis of congenital pneumonia and with a confirmatory test for influenza A (H1N1) virus, without any other suspicious contact. The mother was admitted to the hospital with respiratory failure and the history of a flu-like episode of 5 days of evolution, during the first days of the pandemic in Peru. Due to the severe evolution of the respiratory process, assisted ventilation was given to her and then a cesarean section was performed due to acute fetal distress and oligoamnios. The mother was later confirmed as a case of epidemic influenza A (H1N1) and pulmonary tuberculosis. (AU)


Assuntos
Humanos , Vírus da Influenza A Subtipo H1N1 , Transmissão Vertical de Doença Infecciosa , Trabalho de Parto Prematuro , Pneumonia Viral , Sofrimento Fetal , Peru
18.
Rev. peru. med. exp. salud publica ; 27(2): 292-295, abr.-jun. 2010. tab
Artigo em Espanhol | LILACS | ID: lil-565466

RESUMO

Se describe el caso de un varón de 47 años, con tiempo de enfermedad de dos días, caracterizado por pérdida de fuerza progresiva, simétrica y ascendente de miembros inferiores, se realizó punción lumbar luego de la tomografía cerebral y electromiografía lo cual evidenció polirradiculopatía motora pura con patrón axonal, compatible con el síndrome de Guillain Barré. Posteriormente, recibió cuatro sesiones de plasmaféresis, con mejoría clínica significativa desde la segunda sesión. Debido al antecedente epidemiológico se solicitó set para Brucellas, con rosa de Bengala positivo, se inició tratamiento antibiótico con rifampicina y doxiciclina, además de rehabilitación. Tres meses después el paciente mejoró completamente. La importancia del tratamiento temprano con plasmaféresis y determinar su diagnóstico etiológico hacen que el pronóstico del síndrome de Guillain Barré sea favorable.


We describe a case of a 47 years old male, with a history of 2 days of progressive, ascendant, symmetrical weakness in the lower extremities; a lumbar puncture was performed after the brain CT scan, as well as an electromyography, evidencing pure motor polyradiculopathy with axonal pattern, compatible with Guillain Barre syndrome. Afterwards, he received four plasmapheresis sessions, with clinical improvement from the second session. Due to his epidemiological background, Brucella set testing was done. Rose Bengal was positive, antibiotic treatment with rifampin and doxicicline was initiated, as well as rehabilitation. Three months later the patient recovered completely. The relevance of early treatment with plasmapheresis and the definition of the etiologic diagnosis determine that the prognosis of the Guillain Barre syndrome is favorable.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Brucella , Síndrome de Guillain-Barré , Doenças do Sistema Nervoso Periférico
19.
Rev. peru. epidemiol. (Online) ; 13(2)2009. graf, tab
Artigo em Espanhol | LILACS | ID: lil-619916

RESUMO

Objetivo: Determinar la prevalencia de colonización nasal de Staphylococcus aureus meticilino resistente (SARM), en el personal de salud del servicio de cuidados intensivos del Hospital Nacional Dos de Mayo. Material y métodos: Se realizó un estudio descriptivo transversal. Mediante hisopado nasal se aislaron cepas de S. aureus usando métodos clásicos y se determinó la susceptibilidad a antibióticos de las cepas aisladas, mediante el método de difusión por disco según los estándares del NCCLS. Resultados Se obtuvieron siete aislamientos positivos para S. aureus, de un total de 41 participantes, lo que correspondió a una prevalencia de 17.1%. La prevalencia de SARM fue de 7.3%. El personal de enfermería presentó la mayor prevalencia (4.9%). Conclusiones. El porcentaje de portadores nasales por S. aureus encontrada en este estudio es menor que lo reportado en estudios similares, teniendo en cuenta que la población en estudio es vulnerable a la colonización con este patógeno.


Objective: To determine the prevalence of nasal colonization by methicillin-resistant Staphylococcus aureus (MRSA) in health workers of the intensive care units at Hospital Nacional Dos de Mayo. Methods: A descriptive transversal study was performed. We isolated strains of S. aureus by nasal swabs and using classic methods, and identified antibiotics susceptibility by disk diffusion method according to CLSI standards. Results: We obtained 7 positive results for S. aureus from a total of 41 participants, which corresponded to a prevalence of 17.1%. The prevalence of MRSA was 7.3%. The nursing staff showed the highest prevalence (4.9%). Conclusions: The proportion of S. aureus nasal carriers found in this study is much lower than those reported in similar studies, taking into account that the study population is vulnerable to colonization with this pathogen.


Assuntos
Humanos , Masculino , Feminino , Pessoal de Saúde , Unidades de Terapia Intensiva , Staphylococcus aureus Resistente à Meticilina , Cavidade Nasal , Prevalência , Staphylococcus aureus , Estudos Transversais , Epidemiologia Descritiva , Peru
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